GO:0017124

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Name SH3 domain binding
Categary Function
Go Slim No
Go Link GO:0017124
Unique Molecular Interactions 400
Total Molecular Interactions 499
Total Single Events 3698
Pain Genes Associated 84

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for SH3 domain binding. They are ordered first by their pain relevance and then by number of times they were reported for SH3 domain binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT211694 Binding of Cntnap1 and Nav1 1 0.04 0 3.14
2 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
3 INT231971 Binding of Cpn1 and Shbdp1 1 0.04 1.39 2.26
4 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
5 INT334633 Binding of Cntnap1 and Nav1 1 0.10 1.36 1.48
6 INT158144 Binding of Gpx1 and Glyat 2 0.31 0 1.29
7 INT111211 Binding of Drd4 and Chdh 1 0.01 1.34 1.26
8 INT301166 LRP2 Regulation of TRD@ 1 0.12 1.93 1.21
9 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
10 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
11 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
12 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
13 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
14 INT56990 Cat Regulation of Efs 1 0.26 0 1.05
15 INT348175 Binding of NIDDM1 and PTPN22 1 0.01 2.36 0.99
16 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
17 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
18 INT149925 Negative_regulation of Cpox Negative_regulation of Gene_expression of Pde4d 1 0.01 0.39 0.84
19 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
20 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81
21 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8
22 INT144449 Plscr1 Positive_regulation of Gene_expression of Nqo1 1 0.15 0.18 0.8
23 INT237204 Binding of LGALS4 and Cd3e 1 0.15 2.61 0.8
24 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
25 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
26 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
27 INT37439 Binding of Shbdp1 and Tyr 1 0.01 0 0.76
28 INT353630 Binding of Psmd1 and Shbdp1 1 0.02 0 0.76
29 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
30 INT148454 Gene_expression of Inhbe Positive_regulation of Prkce 1 0.08 0.67 0.69
31 INT104301 Adam17 Regulation of Negative_regulation of Sell 1 0.39 0.58 0.69
32 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
33 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
34 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64
35 INT329961 Binding of IL2RA and PTPN22 1 0.35 1.87 0.63
36 INT73073 Binding of Cd3e and Oprk1 1 0.28 0.06 0.59
37 INT129271 Binding of ANTXR1 and Efs 1 0.00 0 0.56
38 INT182348 Binding of Cd3e and Crp 1 0.15 2.33 0.56
39 INT129269 Binding of Ts3 and Efs 1 0.01 0 0.55
40 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
41 INT129270 Binding of Wnt4 and Efs 1 0.00 0 0.55
42 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
43 INT130561 NCKIPSD Regulation of SERPINF2 1 0.22 0 0.52
44 INT144130 Binding of Gja1 and Prkcg 1 0.48 0.5 0.52
45 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
46 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
47 INT273350 Pde7a Positive_regulation of Localization of Pde4d 1 0.33 1.35 0.49
48 INT172207 Binding of Drd4 and ADHD1 2 0.03 1.56 0.48
49 INT346325 Sirpa Regulation of Obfc1 1 0.00 0.41 0.48
50 INT321045 Anpep Positive_regulation of Protein_catabolism of Ptpn6 1 0.01 0.22 0.48
51 INT151485 Negative_regulation of Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
52 INT173475 Bcar1 Regulation of Isl1 1 0.01 0 0.47
53 INT151484 Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
54 INT265359 Efs Positive_regulation of Car2 1 0.19 0.42 0.45
55 INT321047 Anpep Regulation of Negative_regulation of Ptpn6 1 0.01 0.25 0.43
56 INT161654 Gsr Regulation of Gpx1 1 0.14 0.85 0.42
57 INT168435 Positive_regulation of Binding of GLRX and Gpx1 1 0.05 0.91 0.42
58 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
59 INT168434 Binding of GLRX and Gpx1 1 0.04 0.9 0.42
60 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
61 INT160048 INPPL1 Regulation of Gene_expression of AKT1 1 0.28 0.6 0.42
62 INT351237 HRAS Regulation of CBL 1 0.00 0.48 0.4
63 INT168461 Sult1a1 Positive_regulation of Gpx1 1 0.12 0.83 0.39
64 INT263433 Abl1 Regulation of Abl1 1 0.04 0.28 0.38
65 INT37440 Binding of VCX and Shbdp1 1 0.00 0 0.38
66 INT38274 Binding of TCN1 and Cbl 1 0.11 0.24 0.38
67 INT353391 Binding of DRD4 and GRB2 1 0.37 0.62 0.37
68 INT353392 Binding of DRD4 and NCK1 1 0.37 0.62 0.37
69 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
70 INT353390 Binding of DRD4 and SRC 1 0.25 0.62 0.37
71 INT199285 Tg(Foxn1)E1Hon Regulation of Gene_expression of Mapt 1 0.01 0.52 0.36
72 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
73 INT263383 Abl1 Regulation of Trib3 1 0.01 0.28 0.35
74 INT94473 Binding of Cd3e and Trav6-3 2 0.05 0 0.34
75 INT173476 Th Regulation of Gene_expression of Bcar1 1 0.10 0 0.34
76 INT94474 Binding of Cd3e and Il27ra 1 0.02 0 0.34
77 INT23882 Npy Positive_regulation of Bcar1 1 0.34 0.67 0.34
78 INT292014 Efs Regulation of Localization of Prl 1 0.26 0 0.33
79 INT264504 Binding of CRYGD and PTPN22 1 0.04 0.42 0.31
80 INT258764 Binding of Drd4 and ADHD1 1 0.08 1.11 0.31
81 INT237641 Binding of Cntnap1 and Nfasc 2 0.36 0.1 0.29
82 INT353632 Binding of Shbdp1 and Kncn 1 0.05 0 0.28
83 INT259936 CTLA4 Regulation of PTPN22 1 0.45 1.64 0.28
84 INT47195 EFS Positive_regulation of Localization of Vip 1 0.13 0 0.26
85 INT215289 Siglec1 Regulation of Cyba 1 0.01 0.74 0.26
86 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26
87 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26
88 INT259937 Binding of CSK and PTPN22 1 0.21 1.69 0.25
89 INT351143 Binding of Cd3e and Ighg2a 1 0.00 1.56 0.25
90 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25
91 INT197232 Binding of Grik5 and Kars 1 0.17 0.1 0.25
92 INT250536 Ghrh Positive_regulation of Negative_regulation of Ptpn6 1 0.09 0 0.24
93 INT189674 CHKB Negative_regulation of ASAP1 1 0.08 0 0.24
94 INT165637 Ptpn6 Negative_regulation of Positive_regulation of Nfkb1 1 0.02 0.57 0.23
95 INT237201 Cd3e Positive_regulation of KIT 1 0.03 0 0.21
96 INT202809 Cd3e Positive_regulation of Positive_regulation of Cxcl5 1 0.00 0.5 0.21
97 INT274578 Binding of ABL1 and PSTPIP1 1 0.07 1.55 0.21
98 INT165636 Ptpn6 Regulation of Nfkb1 1 0.01 0.36 0.2
99 INT250537 Ptpn6 Negative_regulation of Igf1 1 0.08 0 0.2
100 INT316072 Binding of Cd3e and Ncam1 1 0.01 0.4 0.18
101 INT316074 Binding of Cd19 and Cd3e 1 0.02 0.39 0.17
102 INT149281 Binding of MAPT and Dbp 1 0.00 0.4 0.17
103 INT316123 Binding of HLA-DRA and BCAR1 1 0.02 0.48 0.16
104 INT277990 Binding of Cd3e and Hand1 1 0.01 0.5 0.16
105 INT172674 Ptpn6 Negative_regulation of Gene_expression of Plat 1 0.02 1.3 0.16
106 INT282708 Binding of MAPT and Y301C7L 1 0.00 0.54 0.16
107 INT354968 Shank3 Positive_regulation of Gene_expression of Gria2 1 0.05 0 0.15
108 INT7296 Binding of HCLS1 and NPPA 1 0.02 1.65 0.15
109 INT252352 Binding of THBS1 and Sirpa 1 0.00 0.26 0.15
110 INT219597 Prkaca Positive_regulation of Pde4d 1 0.29 0 0.15
111 INT279031 Binding of Sirpa and Cd47 1 0.09 0.77 0.15
112 INT287262 Binding of Cyth3 and Shbdp1 1 0.00 0.15 0.14
113 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14
114 INT253009 Igf1 Regulation of PTTG1 1 0.03 0.44 0.13
115 INT134614 Prkce Regulation of Trpv1 1 0.30 0.15 0.13
116 INT252573 Rpe Negative_regulation of Gpx1 1 0.07 2.34 0.13
117 INT253015 Egf Regulation of PTTG1 1 0.02 0.44 0.13
118 INT206424 Binding of NFIA and ASAP1 1 0.33 0 0.13
119 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13
120 INT211313 Binding of Cd3e and Cd8a 1 0.02 0.19 0.13
121 INT143661 Abl1 Regulation of Gpx1 1 0.19 0.56 0.12
122 INT214958 Ss18 Regulation of Rims1 1 0.15 0 0.12
123 INT254488 Dtx1 Regulation of Sorbs1 1 0.01 0 0.12
124 INT110107 Acot1 Positive_regulation of Localization of Prkce 1 0.11 0 0.12
125 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
126 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
127 INT214953 Syt1 Regulation of Rims1 1 0.25 0 0.12
128 INT194814 Cd3e Positive_regulation of Gene_expression of Il4 1 0.05 0 0.12
129 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12
130 INT219599 Pde4d Regulation of Prkaca 1 0.28 0 0.12
131 INT214952 Vamp2 Regulation of Rims1 1 0.17 0 0.12
132 INT254490 Dtx1 Regulation of Gopc 1 0.04 0 0.12
133 INT143662 Rere Regulation of Gpx1 1 0.69 0.56 0.12
134 INT129092 Binding of GRP and Lyn 1 0.00 0.48 0.12
135 INT214956 Vamp1 Regulation of Rims1 1 0.17 0 0.12
136 INT263429 Pdgfb Positive_regulation of Localization of Abl1 1 0.01 0 0.12
137 INT27814 CD2AP Positive_regulation of PADI1 1 0.19 0.06 0.11
138 INT259629 Binding of Adam17 and Timp3 1 0.01 0.19 0.11
139 INT312212 Binding of ADAM12 and INPP5K 1 0.16 0.46 0.11
140 INT255811 Binding of GNAS and MAPT 1 0.00 0.67 0.11
141 INT274583 Binding of ABL1 and PSTPIP2 1 0.06 0.79 0.11
142 INT27815 Regulation of CD2AP Positive_regulation of PADI1 1 0.11 0.06 0.11
143 INT164060 MYLK Positive_regulation of EFS 1 0.08 0.08 0.1
144 INT303179 Binding of Dlgap1 and Shank1 1 0.22 0.31 0.1
145 INT347647 Inpp5d Negative_regulation of Pik3r1 1 0.31 0.37 0.1
146 INT272389 Bcar1 Negative_regulation of Gene_expression of Trpv6 1 0.01 0 0.1
147 INT249117 Binding of Abl1 and Bcr 4 0.36 2.22 0.09
148 INT254492 Dtx1 Regulation of Cldn11 1 0.03 0 0.09
149 INT7295 HCLS1 Positive_regulation of NPPA 1 0.02 0.44 0.09
150 INT219600 Pde4d Regulation of Binding of Prkaca 1 0.28 0 0.09
151 INT252421 Gja1 Regulation of P2ry1 1 0.00 0.28 0.09
152 INT219602 Binding of Prkaca and Pde4d 1 0.23 0 0.09
153 INT269069 Binding of Cyba and Cybb 1 0.18 0.18 0.09
154 INT303180 Trim3 Negative_regulation of Shank1 1 0.40 0 0.09
155 INT269056 Positive_regulation of Binding of Cyba and Cybb 1 0.24 0.18 0.09
156 INT258758 Binding of Drd4 and Lmo1 1 0.04 0.64 0.08
157 INT180200 Binding of BCAR1 and MMVP1 1 0.11 8.57 0.08
158 INT354962 Gene_expression of Shank3 Positive_regulation of Gusb 1 0.10 0.45 0.08
159 INT259938 Binding of CTLA4 and PTPN22 1 0.36 0.85 0.08
160 INT254491 Positive_regulation of Binding of Cntnap1 and Nfasc 1 0.02 0.1 0.08
161 INT148096 Vasp Regulation of Pde2a 1 0.00 0.23 0.08
162 INT238625 Mef2c Regulation of Gene_expression of Syngap1 1 0.10 0.16 0.08
163 INT316792 Binding of HLA-DRB1 and Ptpn22 1 0.07 0.33 0.08
164 INT353070 ADAM17 Positive_regulation of TNF 1 0.19 1.66 0.08
165 INT189957 Binding of LDHA and Pttg1 1 0.05 0.35 0.08
166 INT249166 Phosphorylation of NCF1 Positive_regulation of Localization of GOPC 1 0.03 0.06 0.08
167 INT351142 Binding of Cd3e and Ighg2b 1 0.03 0.6 0.07
168 INT263100 Binding of EFS and COPD 1 0.14 4.14 0.07
169 INT303176 Gene_expression of Trim3 Positive_regulation of Protein_catabolism of Shank1 1 0.44 0 0.07
170 INT333243 Gene_expression of Cxcl12 Negative_regulation of Bcar1 1 0.15 1 0.07
171 INT267000 Mdk Negative_regulation of Positive_regulation of Baiap2 1 0.03 0.1 0.06
172 INT178084 EDNRA Positive_regulation of Phosphorylation of GJA1 1 0.10 0.88 0.06
173 INT293220 Cd3e Regulation of Gene_expression of CNR2 1 0.03 0.06 0.06
174 INT293221 Cd3e Regulation of Gene_expression of CNR1 1 0.03 0.06 0.06
175 INT267040 Negative_regulation of NOS1 Negative_regulation of Positive_regulation of Baiap2 1 0.02 0.1 0.06
176 INT178090 EDN1 Positive_regulation of Phosphorylation of GJA1 1 0.09 0.88 0.06
177 INT237190 Cd3e Positive_regulation of LPT 1 0.00 0.15 0.06
178 INT208432 Sms Negative_regulation of Negative_regulation of Gpx1 1 0.14 0.61 0.05
179 INT257343 Lox Regulation of Cyba 1 0.02 0.37 0.05
180 INT273353 Pde4d Regulation of Gene_expression of Twist1 1 0.26 0.25 0.05
181 INT345245 Adam9 Regulation of Adam10 1 0.09 0.18 0.05
182 INT173477 Bcar1 Regulation of Localization of Ins1 1 0.16 0.07 0.05
183 INT208433 Sms Positive_regulation of Gene_expression of Gpx1 1 0.25 0.53 0.05
184 INT178574 IL2RA Positive_regulation of Gene_expression of Cd3e 1 0.04 0.16 0.05
185 INT253023 Binding of PTTG1 and Myc 1 0.16 0.22 0.04
186 INT354963 Binding of Cttn and Shank1 1 0.12 0 0.04
187 INT295477 Binding of TLR4 and LANCL1 1 0.01 0.16 0.04
188 INT354971 Binding of HOMER1 and Shank1 1 0.01 0 0.04
189 INT148095 Vasp Regulation of Trib3 1 0.00 0.12 0.04
190 INT238803 Ager Positive_regulation of Cbl 1 0.01 1.57 0.04
191 INT293353 Binding of CD8A and Cd3e 1 0.01 0.07 0.04
192 INT347414 Tlr4 Negative_regulation of Gpx1 1 0.01 0.36 0.04
193 INT252897 Binding of PTTG1IP and PTTG1 1 0.04 0.15 0.04
194 INT250780 IRF6 Positive_regulation of ASAP1 1 0.06 0.34 0.04
195 INT252892 PTTG1IP Regulation of PTTG1 1 0.05 0.49 0.04
196 INT239402 Binding of NPPA and ASAP1 1 0.19 1.24 0.04
197 INT263377 Abl1 Regulation of Src 1 0.15 0 0.04
198 INT321683 Binding of Aicda and Mapt 1 0.36 1.23 0.04
199 INT263428 Abl1 Regulation of Pdgfra 1 0.00 0 0.04
200 INT263432 Trib3 Regulation of Abl1 1 0.00 0 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported for SH3 domain binding. They are ordered first by their pain relevance and then by number of times they were reported in SH3 domain binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07
2 INT22579 Localization of Efs 35 0.65 2.77 16.05
3 INT16321 Gene_expression of Cd3e 111 0.72 49.9 14.21
4 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77
5 INT88650 Negative_regulation of Prkce 13 0.57 11.93 11.16
6 INT91948 Positive_regulation of Prkce 16 0.64 11.36 10.32
7 INT72148 Positive_regulation of Prkce 17 0.68 5.06 9.44
8 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83
9 INT18736 Gene_expression of Ptpn6 19 0.59 4.44 8.06
10 INT7378 Negative_regulation of Efs 17 0.37 1.93 7.78
11 INT9491 Positive_regulation of Ptpn6 11 0.51 2.33 7.32
12 INT110104 Localization of Prkce 17 0.79 3.75 6.92
13 INT87775 Phosphorylation of Gja1 13 0.82 2.75 6.56
14 INT8595 Localization of Mapt 26 0.73 6.81 6.41
15 INT130875 Gene_expression of ADAM17 13 0.78 15.46 6.41
16 INT38595 Localization of BCAR1 8 0.73 2.9 6.25
17 INT50975 Localization of Ptpn6 8 0.65 2.64 5.7
18 INT31829 Positive_regulation of Efs 13 0.42 2.83 5.6
19 INT101497 Phosphorylation of Prkce 9 0.81 2.55 5.59
20 INT102836 Binding of LRP2 12 0.38 11.27 5.58
21 INT211690 Gene_expression of Cntnap1 1 0.06 1.03 5.5
22 INT91946 Regulation of Prkce 6 0.44 4.13 5.46
23 INT105775 Gene_expression of Pde4d 31 0.78 4.18 5.21
24 INT109838 Phosphorylation of Prkce 6 0.67 5.26 4.95
25 INT26058 Gene_expression of SH3BP5 12 0.23 2.81 4.88
26 INT1807 Negative_regulation of Bcar1 9 0.38 4.04 4.59
27 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59
28 INT75627 Gene_expression of Mapt 41 0.75 22.1 4.58
29 INT104299 Negative_regulation of Adam17 18 0.47 12.03 4.39
30 INT87780 Gene_expression of Gja1 22 0.77 5.84 4.24
31 INT22580 Negative_regulation of Localization of Efs 9 0.25 0.24 4.24
32 INT88274 Positive_regulation of Drd4 7 0.69 3.48 4.1
33 INT173910 Gene_expression of LRP2 24 0.75 19.99 4.09
34 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02
35 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
36 INT53584 Regulation of Gpx1 19 0.62 14.38 3.48
37 INT109840 Localization of Prkce 5 0.74 3.01 3.45
38 INT6339 Negative_regulation of Ptpn6 6 0.14 0.71 3.44
39 INT25386 Positive_regulation of Cd3e 30 0.62 13.91 3.41
40 INT5729 Negative_regulation of EFS 7 0.50 0.25 3.35
41 INT134786 Gene_expression of Adam10 17 0.68 7.61 3.29
42 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23
43 INT36286 Binding of Cd3e 33 0.36 10.11 3.21
44 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2
45 INT109095 Binding of Drd4 7 0.40 3.6 3.18
46 INT64 Regulation of Ptpn6 12 0.14 2.45 3.17
47 INT110100 Negative_regulation of Prkce 5 0.57 0.68 3.16
48 INT107962 Gene_expression of Pttg1 34 0.53 34.05 3.11
49 INT48437 Positive_regulation of SH3BP5 4 0.20 2.41 3.09
50 INT38594 Positive_regulation of Localization of BCAR1 3 0.63 0.44 3.07
51 INT90289 Positive_regulation of Gene_expression of Gpx1 10 0.17 8.07 3.05
52 INT88273 Gene_expression of Drd4 6 0.54 1.84 3.01
53 INT115348 Localization of Baiap2 1 0.68 1.76 2.99
54 INT7377 Regulation of Efs 6 0.39 0.93 2.91
55 INT102157 Gene_expression of Adam17 3 0.58 4.17 2.86
56 INT147412 Binding of DRD4 11 0.47 7.57 2.77
57 INT321018 Protein_catabolism of Ptpn6 1 0.14 0.52 2.73
58 INT189863 Gene_expression of DRD4 11 0.68 7.65 2.66
59 INT128184 Positive_regulation of Positive_regulation of Prkce 4 0.41 1.3 2.64
60 INT87340 Negative_regulation of BCAR1 8 0.38 6.96 2.63
61 INT88272 Gene_expression of Drd4 5 0.66 1.07 2.53
62 INT79399 Gene_expression of Pde4d 6 0.70 2.83 2.51
63 INT15298 Gene_expression of Efs 10 0.61 0.22 2.48
64 INT107489 Negative_regulation of Pde4d 3 0.42 0 2.47
65 INT61378 Positive_regulation of Bcar1 13 0.45 2.84 2.45
66 INT45168 Negative_regulation of ASAP1 23 0.58 10.15 2.44
67 INT211684 Regulation of Gene_expression of Cntnap1 1 0.04 0.54 2.38
68 INT231573 Binding of PTPN22 5 0.44 7.94 2.33
69 INT172078 Localization of Cd3e 22 0.37 9.88 2.27
70 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
71 INT128185 Gene_expression of Prkce 4 0.69 1.39 2.23
72 INT137629 Binding of Ptpn6 10 0.30 0.42 2.15
73 INT321023 Positive_regulation of Localization of Ptpn6 1 0.07 0.27 2.15
74 INT87778 Positive_regulation of Gene_expression of Gja1 6 0.69 1.46 2.14
75 INT107490 Positive_regulation of Pde4d 3 0.69 0.07 2.13
76 INT130649 Positive_regulation of Cyba 4 0.36 0.38 2.08
77 INT136941 Positive_regulation of Localization of Prkce 3 0.43 1.42 2.06
78 INT124052 Binding of Prkce 2 0.06 2.52 2.03
79 INT105776 Negative_regulation of Gene_expression of Pde4d 5 0.59 2.2 2.01
80 INT130648 Negative_regulation of Positive_regulation of Cyba 1 0.05 0.05 2
81 INT262364 Positive_regulation of LRP2 6 0.39 4.44 1.97
82 INT204139 Positive_regulation of Gene_expression of BCAR1 1 0.23 0.9 1.96
83 INT87779 Positive_regulation of Gja1 4 0.53 0.9 1.95
84 INT128030 Gene_expression of GJA1 23 0.75 7.81 1.88
85 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87
86 INT117346 Positive_regulation of ADAM17 5 0.50 6.69 1.86
87 INT87776 Positive_regulation of Phosphorylation of Gja1 3 0.62 0.71 1.86
88 INT45167 Positive_regulation of ASAP1 32 0.60 17.09 1.84
89 INT99416 Negative_regulation of Bcar1 1 0.34 0.64 1.84
90 INT112270 Negative_regulation of Cntnap1 4 0.57 1.74 1.76
91 INT130874 Negative_regulation of Gene_expression of ADAM17 3 0.43 5.03 1.76
92 INT94848 Negative_regulation of Gene_expression of Gpx1 11 0.30 4.91 1.7
93 INT23881 Gene_expression of Bcar1 8 0.52 2.48 1.69
94 INT263398 Positive_regulation of Abl1 1 0.60 1.44 1.66
95 INT174656 Binding of NCF1 5 0.37 6.46 1.65
96 INT22581 Positive_regulation of Localization of Efs 3 0.03 0 1.63
97 INT107341 Phosphorylation of MAPT 19 0.80 14 1.61
98 INT130332 Gene_expression of Adam17 14 0.50 4.84 1.56
99 INT67869 Transcription of Gpx1 3 0.68 0.67 1.56
100 INT138083 Positive_regulation of Gene_expression of Drd4 2 0.40 1.34 1.55
101 INT152567 Positive_regulation of Gene_expression of CYBA 1 0.17 0.67 1.51
102 INT152563 Gene_expression of CYBA 3 0.33 0.82 1.5
103 INT114270 Gene_expression of Plscr1 6 0.47 1.33 1.49
104 INT29856 Negative_regulation of Positive_regulation of Ptpn6 3 0.38 1.24 1.47
105 INT211685 Binding of Cntnap1 1 0.04 0.18 1.42
106 INT189948 Gene_expression of Pttg1 106 0.76 104.68 1.41
107 INT242902 Gene_expression of NCF1 12 0.78 9.34 1.36
108 INT115350 Positive_regulation of Localization of Baiap2 1 0.45 0.76 1.36
109 INT3404 Binding of BCAR1 10 0.33 7.97 1.33
110 INT78861 Negative_regulation of Transcription of Adam17 2 0.29 1.4 1.32
111 INT70954 Negative_regulation of Cd3e 11 0.41 4.22 1.31
112 INT78859 Transcription of Adam17 2 0.47 1.39 1.31
113 INT61999 Gene_expression of MAPT 19 0.75 15.4 1.3
114 INT69498 Positive_regulation of DRD4 3 0.50 0.95 1.3
115 INT91947 Negative_regulation of Negative_regulation of Prkce 1 0.42 0.69 1.3
116 INT316787 Binding of Ptpn22 1 0.29 3.61 1.29
117 INT135924 Positive_regulation of Gene_expression of Pde4d 2 0.59 0 1.28
118 INT205952 Gene_expression of Shbdp1 14 0.24 2.46 1.27
119 INT37432 Binding of Shbdp1 7 0.11 1.6 1.27
120 INT92941 Binding of ASAP1 24 0.39 12.38 1.25
121 INT110099 Positive_regulation of Localization of Prkce 4 0.68 1.3 1.25
122 INT56805 Localization of SH3BP5 2 0.70 0.42 1.25
123 INT26061 Positive_regulation of Gene_expression of SH3BP5 2 0.13 1.28 1.25
124 INT21167 Regulation of NCF1 3 0.15 0.75 1.24
125 INT91949 Regulation of Positive_regulation of Prkce 1 0.44 0.72 1.24
126 INT149924 Negative_regulation of Gene_expression of Pde4d 1 0.26 0.81 1.24
127 INT234893 Positive_regulation of Adam17 4 0.38 3.78 1.22
128 INT110106 Regulation of Prkce 4 0.44 0.4 1.2
129 INT63923 Binding of Mapt 4 0.47 6.28 1.19
130 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17
131 INT98595 Regulation of ILK 6 0.62 3.84 1.16
132 INT128413 Positive_regulation of Shank1 2 0.70 0.61 1.16
133 INT314388 Positive_regulation of Gene_expression of Ptpn6 3 0.11 0.05 1.15
134 INT321016 Regulation of Positive_regulation of Ptpn6 1 0.05 0.05 1.15
135 INT173916 Regulation of LRP2 6 0.44 7.96 1.14
136 INT110102 Negative_regulation of Localization of Prkce 3 0.49 0.17 1.13
137 INT131238 Negative_regulation of Positive_regulation of Prkce 1 0.41 0.44 1.12
138 INT321020 Regulation of Protein_catabolism of Ptpn6 1 0.06 0.05 1.12
139 INT102758 Negative_regulation of Abl1 2 0.51 1.13 1.1
140 INT107961 Positive_regulation of Gene_expression of Pttg1 2 0.38 11.69 1.09
141 INT183820 Regulation of BCAR1 4 0.39 3.27 1.06
142 INT274898 Positive_regulation of Positive_regulation of Lyn 1 0.35 1.51 1.05
143 INT202264 Positive_regulation of Pttg1 8 0.45 8.03 1.04
144 INT89887 Regulation of Gene_expression of Gpx1 3 0.32 0.8 1.02
145 INT132435 Negative_regulation of ADAM17 2 0.50 3.75 1.02
146 INT219589 Binding of Pde4d 13 0.47 0.51 1.01
147 INT63922 Positive_regulation of Binding of Mapt 1 0.49 0.25 1.01
148 INT134822 Gene_expression of Gja1 18 0.72 4.2 1
149 INT219568 Positive_regulation of Pde4d 9 0.49 1.74 1
150 INT126672 Binding of Bcar1 7 0.20 2.67 0.98
151 INT8594 Negative_regulation of Mapt 5 0.57 4.47 0.98
152 INT135111 Regulation of Gene_expression of Prkce 1 0.51 0.15 0.96
153 INT135115 Regulation of Localization of Prkce 1 0.38 0.15 0.96
154 INT141936 Phosphorylation of Mapt 14 0.80 10.59 0.95
155 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95
156 INT128411 Regulation of Shank1 2 0.45 0.81 0.95
157 INT125903 Gene_expression of Espn 2 0.06 0.77 0.94
158 INT123948 Positive_regulation of Plscr1 4 0.42 1.02 0.93
159 INT204136 Regulation of Gene_expression of BCAR1 2 0.21 0.62 0.93
160 INT26063 Regulation of SH3BP5 2 0.45 1.99 0.92
161 INT65835 Gene_expression of EFS 1 0.37 0 0.92
162 INT263387 Binding of Abl1 8 0.42 0.86 0.91
163 INT149383 Binding of Lyn 1 0.36 1.14 0.91
164 INT168534 Gene_expression of Grik5 3 0.38 0.64 0.9
165 INT211601 Gene_expression of Rims1 1 0.21 1.63 0.89
166 INT43947 Localization of ASAP1 11 0.68 4.49 0.88
167 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87
168 INT205949 Positive_regulation of Shbdp1 7 0.15 1.58 0.85
169 INT278709 Gene_expression of CBL 4 0.14 3.91 0.85
170 INT136944 Positive_regulation of Positive_regulation of Prkce 2 0.46 0.8 0.85
171 INT114275 Regulation of Gene_expression of Plscr1 2 0.24 0.51 0.85
172 INT180100 Positive_regulation of Adam10 6 0.33 2 0.84
173 INT70496 Positive_regulation of EFS 3 0.29 0.2 0.84
174 INT173581 Gene_expression of ADAM12 4 0.38 1.46 0.83
175 INT203739 Negative_regulation of NCF1 2 0.27 1.22 0.82
176 INT88271 Positive_regulation of Drd4 2 0.19 0.5 0.82
177 INT38272 Positive_regulation of Cbl 1 0.27 0.82 0.82
178 INT87777 Regulation of Gja1 1 0.62 0.76 0.81
179 INT219578 Negative_regulation of Pde4d 3 0.46 2.95 0.8
180 INT135923 Regulation of Gene_expression of Pde4d 2 0.44 0 0.8
181 INT118753 Regulation of Negative_regulation of Pde4d 1 0.02 0 0.8
182 INT48620 Negative_regulation of Positive_regulation of Efs 2 0.15 0 0.79
183 INT173914 Regulation of Gene_expression of LRP2 3 0.60 6.49 0.78
184 INT23269 Localization of EFS 1 0.34 0 0.78
185 INT134789 Negative_regulation of Gene_expression of Adam10 1 0.30 1.22 0.78
186 INT174492 Positive_regulation of Gene_expression of Cd3e 8 0.39 5.08 0.77
187 INT199573 Gene_expression of Abl1 33 0.65 20.79 0.75
188 INT241499 Binding of Abl1 23 0.47 8.86 0.75
189 INT68297 Binding of MAPT 9 0.47 4.45 0.75
190 INT168432 Negative_regulation of Positive_regulation of Gpx1 4 0.40 2.89 0.75
191 INT143306 Positive_regulation of Gja1 3 0.50 0.42 0.75
192 INT252975 Positive_regulation of Gene_expression of PTTG1 36 0.28 31.96 0.74
193 INT178116 Phosphorylation of GJA1 7 0.80 4.09 0.74
194 INT128402 Negative_regulation of Phosphorylation of Gja1 1 0.58 0.73 0.73
195 INT156685 Regulation of ASAP1 8 0.22 1.94 0.71
196 INT109839 Positive_regulation of Phosphorylation of Prkce 1 0.18 1.27 0.71
197 INT154761 Positive_regulation of Gene_expression of Prkce 1 0.44 0.5 0.7
198 INT154762 Negative_regulation of Phosphorylation of Prkce 1 0.38 0.48 0.69
199 INT260352 Positive_regulation of Gene_expression of NCF1 1 0.50 3.34 0.69
200 INT152909 Regulation of Gene_expression of Gja1 1 0.61 0.46 0.69
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