GO:0017187

From wiki-pain
Jump to: navigation, search
Name peptidyl-glutamic acid carboxylation
Categary Process
Go Slim No
Go Link GO:0017187
Unique Molecular Interactions 134
Total Molecular Interactions 205
Total Single Events 1238
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for peptidyl-glutamic acid carboxylation. They are ordered first by their pain relevance and then by number of times they were reported for peptidyl-glutamic acid carboxylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139723 PROC Positive_regulation of MAPK8 1 0.01 2.98 2.33
2 INT139722 PROC Positive_regulation of CDCP1 1 0.00 1.61 1.29
3 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25
4 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
5 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92
6 INT138602 Negative_regulation of BCL2L2 Positive_regulation of F2 1 0.00 0.67 0.92
7 INT138601 BCL2L2 Positive_regulation of F2 1 0.00 0.66 0.91
8 INT298730 PROC Positive_regulation of Gene_expression of Ngf 1 0.00 0.6 0.74
9 INT106999 F2 Positive_regulation of PAR4 3 0.06 1.83 0.72
10 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
11 INT126781 Binding of F10 and Serpinc1 1 0.00 1.51 0.69
12 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
13 INT150338 Binding of F2 and F2R 1 0.11 0.4 0.67
14 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62
15 INT145491 PROC Positive_regulation of Cpox 1 0.00 1.08 0.58
16 INT195666 Binding of PROC and THBD 2 0.40 2.42 0.56
17 INT298729 PROC Positive_regulation of Set 1 0.00 0.76 0.55
18 INT84515 IRF6 Positive_regulation of Gene_expression of F2 1 0.02 0.15 0.49
19 INT84520 Gene_expression of F2 Positive_regulation of F13A1 1 0.03 0.16 0.49
20 INT92803 Binding of CYP1A2 and VKORC1 1 0.31 0.12 0.48
21 INT92804 Positive_regulation of Binding of CYP1A2 and VKORC1 1 0.41 0.12 0.48
22 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
23 INT341622 Binding of F2 and CTRC 1 0.06 1.22 0.46
24 INT173295 F2 Positive_regulation of OR1S1 1 0.01 0.15 0.46
25 INT162043 F2 Positive_regulation of Gene_expression of OSM 1 0.44 1.13 0.41
26 INT162041 F2 Positive_regulation of Positive_regulation of FOS 1 0.13 1.14 0.41
27 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37
28 INT84521 Binding of F7 and TF 1 0.06 0.09 0.37
29 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35
30 INT95644 PROC Negative_regulation of NPEPPS 1 0.00 1.24 0.35
31 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33
32 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32
33 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32
34 INT123397 F2 Positive_regulation of Gene_expression of PTAFR 1 0.05 0.51 0.32
35 INT162042 F2 Regulation of OSM 1 0.17 1.17 0.31
36 INT257735 GAS6 Positive_regulation of Gene_expression of SAGE1 1 0.04 0.98 0.31
37 INT195669 Binding of F2 and PROC 1 0.04 1.44 0.31
38 INT191799 PROC Negative_regulation of Binding of F2r 1 0.00 0.92 0.3
39 INT162045 F2 Positive_regulation of Phosphorylation of MAPK3 1 0.30 0.99 0.3
40 INT162039 F2 Regulation of Gene_expression of OSM 1 0.29 0.94 0.29
41 INT162044 F2 Positive_regulation of Localization of FOS 1 0.32 0.9 0.28
42 INT247081 Binding of F5 and F7 1 0.00 0.87 0.28
43 INT162040 F2 Positive_regulation of Localization of JUN 1 0.20 0.9 0.28
44 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27
45 INT282646 Binding of PROC and PROCR 1 0.40 0.99 0.26
46 INT220681 Binding of F10 and tf 1 0.03 1.47 0.26
47 INT308120 Binding of F2 and F10 2 0.07 1.25 0.25
48 INT341538 F2 Positive_regulation of F2RL1 1 0.02 0.68 0.24
49 INT348364 PROC Negative_regulation of TNF 1 0.01 0.89 0.23
50 INT63420 F2 Positive_regulation of Gene_expression of ITGA2B 1 0.14 0.45 0.23
51 INT63421 F2 Positive_regulation of Gene_expression of SELP 1 0.09 0.45 0.23
52 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
53 INT173292 F2 Positive_regulation of EGF 1 0.00 0.07 0.23
54 INT69390 Binding of PENK and PROC 1 0.00 0.22 0.21
55 INT348363 PCTP Positive_regulation of PROC 1 0.01 0.41 0.2
56 INT348372 Binding of PROC and Stard10 1 0.01 0.41 0.2
57 INT117517 PROC Positive_regulation of PTGS2 1 0.01 0.61 0.19
58 INT220682 tf Positive_regulation of Positive_regulation of F10 1 0.04 0.67 0.19
59 INT210029 PROC Negative_regulation of PRTN3 1 0.00 1.06 0.18
60 INT247084 Binding of F7 and H1F0 1 0.00 0.38 0.17
61 INT326390 Binding of PROC and Ezr 1 0.00 1 0.17
62 INT83514 SERPINC1 Negative_regulation of F2 2 0.16 0.62 0.16
63 INT281319 Binding of F7 and tf 1 0.24 1 0.16
64 INT83512 F2 Negative_regulation of PLAU 1 0.27 0.57 0.16
65 INT109887 F2 Negative_regulation of F8 1 0.00 1.32 0.16
66 INT83513 Negative_regulation of SERPINC1 Negative_regulation of F2 1 0.16 0.64 0.16
67 INT83515 F2 Positive_regulation of PLAU 1 0.31 0.57 0.16
68 INT83511 F2 Negative_regulation of PRH1 1 0.01 0.6 0.15
69 INT37659 IGHG3 Negative_regulation of F2 1 0.06 0.79 0.15
70 INT240768 Binding of F2 and F13A1 1 0.07 2.25 0.15
71 INT288026 PROC Positive_regulation of Gene_expression of VEGFA 1 0.01 0.5 0.15
72 INT109886 F2 Negative_regulation of Serpinc1 1 0.00 1.18 0.15
73 INT191001 F3 Positive_regulation of F2 1 0.00 0.62 0.14
74 INT107005 F2 Positive_regulation of PRSS1 1 0.00 0.28 0.13
75 INT195662 Binding of PROC and KAT8 1 0.10 2.25 0.12
76 INT326387 Binding of PROC and Rhoa 1 0.00 0.59 0.12
77 INT195710 SERPINC1 Positive_regulation of F2 1 0.08 0.69 0.11
78 INT195711 Negative_regulation of SERPINC1 Positive_regulation of F2 1 0.08 0.7 0.11
79 INT266683 IL1B Positive_regulation of Gene_expression of PROC 1 0.00 1.62 0.11
80 INT8673 Binding of F2 and F8 1 0.08 0.48 0.1
81 INT8672 Positive_regulation of Binding of F2 and F8 1 0.11 0.48 0.1
82 INT8675 Positive_regulation of Binding of F2 and F3 2 0.17 0.43 0.09
83 INT8671 Binding of F2 and F3 2 0.13 0.42 0.09
84 INT298502 F10 Positive_regulation of F2 1 0.00 0.12 0.09
85 INT65958 PROC Positive_regulation of NDUFA1 1 0.00 0.31 0.09
86 INT61217 Negative_regulation of PRTN3 Negative_regulation of F2 1 0.01 0.16 0.08
87 INT195777 THBD Positive_regulation of PROC 1 0.00 1.26 0.08
88 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08
89 INT191002 F2 Positive_regulation of Gene_expression of IL8 1 0.02 0.46 0.06
90 INT326388 Binding of PROC and Slc9a3r2 1 0.00 1.26 0.06
91 INT266082 PROC Regulation of Localization of VEGFA 1 0.00 0.84 0.05
92 INT222684 TEAD1 Negative_regulation of PROC 1 0.01 0.39 0.05
93 INT348365 Binding of PROC and TNF 1 0.00 0.19 0.05
94 INT262256 Binding of PROC and AMIGO2 1 0.00 0.72 0.04
95 INT269575 F2 Positive_regulation of CSH1 1 0.00 0.09 0.04
96 INT269579 F2 Positive_regulation of PAFAH2 1 0.00 0.09 0.04
97 INT213422 MITF Negative_regulation of PROC 1 0.00 0.52 0.03
98 INT261733 F2 Regulation of COL5A2 1 0.03 0.21 0.03
99 INT324593 Binding of PROC and RNASEL 1 0.01 0.91 0.03
100 INT260318 Binding of PROC and Anxa5 1 0.00 0 0
101 INT294436 Positive_regulation of Binding of F2 and THBD 1 0.05 0.57 0
102 INT354566 F2 Positive_regulation of PRNP 1 0.00 0.05 0
103 INT308125 Binding of CA2 and F2 1 0.01 0.23 0
104 INT255012 TF Positive_regulation of F10 1 0.06 0.06 0
105 INT212527 Binding of PROC and Crp 1 0.00 1.5 0
106 INT208364 Hdl1 Positive_regulation of Localization of PROC 1 0.00 1.13 0
107 INT206055 F2 Positive_regulation of Gene_expression of IL6 1 0.01 1.24 0
108 INT70769 Fga Regulation of F2 1 0.00 0.65 0
109 INT223283 Binding of CYP2C9 and VKORC1 1 0.31 0.16 0
110 INT208365 Apoc3 Positive_regulation of Localization of PROC 1 0.00 1.13 0
111 INT326389 Binding of PROC and Eras 1 0.00 0 0
112 INT189561 Binding of F2 and GPER 1 0.00 0.34 0
113 INT354487 Binding of F9 and PLEK 1 0.52 0.14 0
114 INT297740 Cbr1 Negative_regulation of Positive_regulation of PROC 1 0.00 0.42 0
115 INT55160 Binding of PROC and REL 1 0.01 0.09 0
116 INT261732 F2 Positive_regulation of F2R 1 0.14 0 0
117 INT202987 Binding of F2 and ANGPTL5 1 0.07 0.07 0
118 INT326386 Binding of PROC and Gopc 1 0.00 0 0
119 INT195661 Binding of APC and PROC 1 0.23 0.89 0
120 INT55166 Binding of PROC and RELA 1 0.01 0.09 0
121 INT344000 PROC Positive_regulation of PRNP 1 0.00 0.07 0
122 INT234440 Binding of PROC and RARA 1 0.00 0.73 0
123 INT350168 Binding of DMD and PROC 1 0.00 0.67 0
124 INT59460 F2 Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.14 0
125 INT255019 Myo7a Positive_regulation of F10 1 0.00 0.06 0
126 INT308121 Binding of CA2 and F10 1 0.04 0.23 0
127 INT297741 Cbr1 Negative_regulation of PROC 1 0.00 0.4 0
128 INT212526 Binding of PROC and Apcs 1 0.01 2.54 0
129 INT195659 APC Positive_regulation of Gene_expression of PROC 1 0.26 0.31 0
130 INT195703 Positive_regulation of SERPINC1 Negative_regulation of F2 1 0.08 0 0
131 INT341628 Binding of ADAR and PROC 1 0.03 5.01 0
132 INT261735 Positive_regulation of F2 Positive_regulation of F2R 1 0.14 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for peptidyl-glutamic acid carboxylation. They are ordered first by their pain relevance and then by number of times they were reported in peptidyl-glutamic acid carboxylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75
2 INT4535 Localization of PROC 106 0.73 76.24 21.1
3 INT1767 Positive_regulation of PROC 83 0.67 54.14 17
4 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79
5 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
6 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
7 INT1168 Binding of PROC 62 0.38 44.15 9.04
8 INT4534 Regulation of PROC 38 0.33 19.81 8.99
9 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51
10 INT9842 Binding of F2 36 0.47 22.79 4.42
11 INT35609 Negative_regulation of F10 37 0.57 17.15 4.41
12 INT14447 Localization of F2 20 0.79 12.77 2.67
13 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53
14 INT39560 Positive_regulation of F10 25 0.67 10.67 2.5
15 INT16461 Negative_regulation of Gene_expression of PROC 13 0.24 4.39 2.17
16 INT9840 Positive_regulation of F7 17 0.57 17.83 2.08
17 INT55962 Positive_regulation of Localization of PROC 9 0.20 7.76 1.87
18 INT69000 Positive_regulation of Gene_expression of PROC 6 0.20 5.87 1.84
19 INT88523 Positive_regulation of Negative_regulation of PROC 4 0.01 3.76 1.76
20 INT122058 Negative_regulation of VKORC1 1 0.39 0.18 1.63
21 INT88667 Negative_regulation of Gene_expression of F2 11 0.41 5.53 1.62
22 INT1768 Negative_regulation of Positive_regulation of PROC 5 0.41 2.8 1.51
23 INT55979 Protein_catabolism of PROC 8 0.22 2.8 1.49
24 INT12035 Regulation of F2 21 0.45 12.66 1.47
25 INT65319 Transcription of PROC 6 0.01 2.96 1.44
26 INT96132 Gene_expression of F10 10 0.58 6.99 1.24
27 INT138343 Positive_regulation of Localization of F2 5 0.41 5.06 1.24
28 INT55980 Positive_regulation of Protein_catabolism of PROC 1 0.16 1.64 1.04
29 INT174273 Positive_regulation of Binding of F2 3 0.08 2.99 1.02
30 INT257763 Positive_regulation of Gene_expression of GAS6 1 0.32 3.4 1.02
31 INT122057 Regulation of VKORC1 1 0.18 0.05 0.83
32 INT82845 Binding of F10 25 0.37 7.07 0.81
33 INT257762 Positive_regulation of GAS6 1 0.32 2.7 0.81
34 INT56406 Regulation of Gene_expression of PROC 4 0.05 1.52 0.79
35 INT257759 Gene_expression of GAS6 1 0.36 2.61 0.78
36 INT138606 Negative_regulation of Positive_regulation of F2 2 0.12 0.54 0.74
37 INT120012 Negative_regulation of Transcription of PROC 1 0.00 0.97 0.71
38 INT107779 Negative_regulation of F7 3 0.30 2.99 0.66
39 INT305315 Positive_regulation of Positive_regulation of PROC 3 0.49 1.52 0.64
40 INT168000 Protein_catabolism of F2 6 0.63 2.19 0.63
41 INT3201 Positive_regulation of F9 11 0.49 5.12 0.56
42 INT320172 Negative_regulation of Binding of F2 2 0.41 1.92 0.5
43 INT55981 Negative_regulation of Binding of PROC 1 0.15 0 0.48
44 INT162049 Phosphorylation of F2 3 0.47 0.99 0.39
45 INT200523 Regulation of F7 2 0.01 1.82 0.38
46 INT247095 Binding of F7 2 0.03 1.91 0.37
47 INT161436 Transcription of F2 2 0.69 1.21 0.36
48 INT162051 Positive_regulation of Phosphorylation of F2 1 0.29 0.99 0.3
49 INT255014 Negative_regulation of Binding of F10 7 0.34 1.81 0.28
50 INT162802 Regulation of Gene_expression of F2 3 0.37 1.56 0.26
51 INT90653 Negative_regulation of Negative_regulation of F10 1 0.04 0.67 0.25
52 INT198659 Protein_catabolism of F10 1 0.01 0.51 0.22
53 INT221999 Gene_expression of F7 2 0.65 2.1 0.2
54 INT287790 Positive_regulation of Gene_expression of F7 1 0.49 1.55 0.2
55 INT94854 Regulation of Negative_regulation of F2 1 0.11 0.18 0.18
56 INT284156 Positive_regulation of Negative_regulation of F2 1 0.01 1.71 0.15
57 INT313645 Regulation of Positive_regulation of F10 1 0.19 0.49 0.14
58 INT313646 Regulation of F10 1 0.19 0.49 0.14
59 INT174262 Negative_regulation of Positive_regulation of F10 2 0.41 0.83 0.08
60 INT129458 Regulation of Localization of F7 1 0.19 0.33 0.08
61 INT129459 Localization of F7 1 0.31 0.33 0.08
62 INT96131 Positive_regulation of Gene_expression of F10 1 0.14 0.72 0.07
63 INT9843 Negative_regulation of Positive_regulation of F7 1 0.48 0.83 0.06
64 INT195677 Regulation of Positive_regulation of PROC 1 0.22 1.57 0.06
65 INT242195 Positive_regulation of Negative_regulation of F10 1 0.01 0.34 0.03
66 INT313644 Negative_regulation of Gene_expression of F10 1 0.34 1.02 0.03
67 INT284149 Negative_regulation of Localization of F2 1 0.05 0.13 0.03
68 INT213647 Gene_expression of F9 10 0.65 6.48 0
69 INT81028 Negative_regulation of F9 3 0.49 2.14 0
70 INT212047 Phosphorylation of PROC 2 0.13 1.41 0
71 INT240052 Negative_regulation of Gene_expression of F9 2 0.04 1.32 0
72 INT10137 Negative_regulation of Positive_regulation of F9 1 0.00 0 0
73 INT308127 Positive_regulation of Localization of F10 1 0.35 0.11 0
74 INT195682 Positive_regulation of Binding of PROC 1 0.25 0 0
75 INT217203 Positive_regulation of Phosphorylation of PROC 1 0.01 1.96 0
76 INT222000 Regulation of Gene_expression of F7 1 0.08 0.76 0
77 INT316083 Regulation of Regulation of F2 1 0.44 1.55 0
78 INT325340 Positive_regulation of Binding of F10 1 0.09 0.37 0
79 INT56405 Negative_regulation of Localization of PROC 1 0.08 0 0
80 INT222002 Negative_regulation of Gene_expression of F7 1 0.13 0.57 0
81 INT223290 Binding of VKORC1 1 0.39 0.16 0
82 INT265506 Binding of F9 1 0.03 0.38 0
83 INT209319 Gene_expression of VKORC1 1 0.01 1.95 0
84 INT308128 Localization of F10 1 0.52 0.88 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox