GO:0018107

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Name peptidyl-threonine phosphorylation
Categary Process
Go Slim No
Go Link GO:0018107
Unique Molecular Interactions 963
Total Molecular Interactions 1155
Total Single Events 10169
Pain Genes Associated 37

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for peptidyl-threonine phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for peptidyl-threonine phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
2 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
3 INT139723 PROC Positive_regulation of MAPK8 1 0.01 2.98 2.33
4 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
5 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
6 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
7 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
8 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
9 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
10 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
11 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
12 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
13 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
14 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
15 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
16 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
17 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
18 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
19 INT134679 FSCN1 Positive_regulation of MAPK8 1 0.01 0.56 1.39
20 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
21 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
22 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
23 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
24 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
25 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13
26 INT68154 Mthfs Positive_regulation of Pdpk1 1 0.01 0.63 1.12
27 INT68158 Pla2g1b Positive_regulation of Pdpk1 1 0.05 0.63 1.12
28 INT68159 Pla2g1b Positive_regulation of Positive_regulation of Pdpk1 1 0.05 0.64 1.12
29 INT68163 Mthfs Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.12
30 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12
31 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
32 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
33 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
34 INT167429 Negative_regulation of Mapk8 Negative_regulation of RYBP 1 0.01 1.11 1.09
35 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
36 INT107938 POMC Positive_regulation of Gene_expression of TGFBR2 1 0.42 1.09 1.07
37 INT83936 Binding of Mtap2 and Penk 1 0.22 0.19 1.07
38 INT223875 Negative_regulation of Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.31 0 1.07
39 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
40 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
41 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1
42 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
43 INT211745 Gnptab Regulation of Positive_regulation of Prkca 1 0.00 0 0.96
44 INT123051 Gpbar1 Regulation of Phosphorylation of Prkca 1 0.43 0 0.94
45 INT123050 Prkca Regulation of Phosphorylation of Grk4 1 0.33 0 0.94
46 INT123048 Grk4 Regulation of Phosphorylation of Prkca 1 0.33 0 0.94
47 INT123053 Prkca Regulation of Phosphorylation of Gpbar1 1 0.43 0 0.94
48 INT107335 Pdpk1 Positive_regulation of Regulation of Sigmar1 1 0.02 0 0.93
49 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
50 INT167771 Prkca Positive_regulation of Phosphorylation of Sigmar1 1 0.38 0.23 0.89
51 INT317515 Binding of Hint1 and Prkca 1 0.13 0.17 0.87
52 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
53 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
54 INT146495 Snta1 Positive_regulation of Adrbk1 1 0.14 0.68 0.85
55 INT110236 Hk1 Regulation of CSAD 1 0.01 1.57 0.84
56 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.08 0.83
57 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82
58 INT190869 Binding of Prkca and Ltp 1 0.03 0.86 0.81
59 INT107937 POMC Regulation of Gene_expression of TGFBR2 1 0.28 0.82 0.81
60 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
61 INT282063 Ngf Positive_regulation of Positive_regulation of Prkca 1 0.09 0.18 0.8
62 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8
63 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79
64 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78
65 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
66 INT157914 Trpv1 Regulation of Prkca 1 0.07 0.55 0.78
67 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78
68 INT157917 TRPV1 Regulation of Prkca 1 0.04 0.55 0.78
69 INT152234 Mapk8 Positive_regulation of Localization of Nfkb1 1 0.33 0.26 0.78
70 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
71 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77
72 INT124384 ADRBK1 Negative_regulation of MC1R 1 0.40 0.42 0.77
73 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
74 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
75 INT98179 Aap Positive_regulation of Mapk8 1 0.01 0.75 0.74
76 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
77 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
78 INT154193 Binding of KCNK2 and Mtap2 1 0.22 0.48 0.74
79 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
80 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74
81 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
82 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72
83 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71
84 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
85 INT223873 Mapk8 Regulation of Positive_regulation of Ltp 1 0.24 0 0.71
86 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
87 INT140235 ADRBK1 Positive_regulation of Binding of MC1R 1 0.46 0.31 0.68
88 INT140237 Gene_expression of ADRBK1 Positive_regulation of Gene_expression of MC1R 1 0.46 0.31 0.68
89 INT223869 Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.20 0 0.68
90 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66
91 INT110458 Binding of Atf2 and Mapk8 1 0.35 0 0.66
92 INT330046 Mapk8 Negative_regulation of Prkcg 1 0.13 0.4 0.66
93 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
94 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
95 INT158685 ROS1 Regulation of Positive_regulation of MAPK8 1 0.21 0.39 0.64
96 INT100030 TNF Positive_regulation of Mapk8 1 0.12 1.57 0.63
97 INT169295 PTPLA Positive_regulation of MAPK8 1 0.10 0.15 0.63
98 INT128812 Mapk8 Negative_regulation of Gene_expression of Nos2 1 0.19 0.37 0.61
99 INT221246 Prkca Negative_regulation of Ptpn2 1 0.04 0.54 0.6
100 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58
101 INT166300 Adrbk1 Positive_regulation of Negative_regulation of Gpbar1 1 0.39 0.63 0.58
102 INT278689 TNF Positive_regulation of MAPK8 1 0.04 0.79 0.56
103 INT296483 Prkca Positive_regulation of Localization of GRIP1 1 0.02 0.31 0.55
104 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55
105 INT200913 Dio1 Positive_regulation of Mapk8 1 0.00 0 0.53
106 INT182553 Ptger2 Regulation of Localization of Prkca 1 0.08 0.69 0.53
107 INT5631 Ubqln1 Positive_regulation of Pdpk1 1 0.05 0 0.53
108 INT106394 MAPK3 Positive_regulation of ADRBK1 1 0.48 0.06 0.53
109 INT137685 Phosphorylation of Prkca Negative_regulation of Binding of Srpx2 1 0.18 0 0.53
110 INT79593 Binding of Reg1 and LMTK2 1 0.00 0.32 0.53
111 INT235876 Hspg2 Positive_regulation of Prkca 1 0.03 0.23 0.53
112 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52
113 INT106392 ADRBK1 Regulation of Negative_regulation of OPRL1 1 0.27 0.06 0.52
114 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
115 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
116 INT151220 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Prkca 1 0.00 0.13 0.51
117 INT151222 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Adrbk1 1 0.00 0.13 0.51
118 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
119 INT151223 Negative_regulation of SIGMAR1 Negative_regulation of Adrbk1 1 0.00 0.13 0.51
120 INT151219 Negative_regulation of SIGMAR1 Negative_regulation of Prkca 1 0.00 0.13 0.51
121 INT120384 PRKCD Positive_regulation of Localization of HSPG2 1 0.29 0.42 0.51
122 INT120382 PRKCD Positive_regulation of Localization of DYT10 1 0.29 0.42 0.51
123 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
124 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
125 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
126 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
127 INT54503 Pomc Positive_regulation of Gene_expression of Pbk 1 0.00 0 0.48
128 INT81331 ADRBK1 Regulation of OPRK1 1 0.03 0.09 0.48
129 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
130 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
131 INT296466 Prkca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
132 INT254225 Mapk14 Positive_regulation of Mapk8 1 0.02 0.87 0.46
133 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46
134 INT95469 P2ry6 Positive_regulation of Positive_regulation of Pdpk1 1 0.15 0 0.46
135 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
136 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
137 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
138 INT244050 Binding of Gnb2l1 and Prkca 1 0.01 0 0.45
139 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44
140 INT191896 Pbsn Positive_regulation of Prkca 1 0.04 0.85 0.44
141 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
142 INT278950 MAPK8 Negative_regulation of Localization of EPHB2 1 0.25 0.47 0.43
143 INT264476 Il1a Positive_regulation of Gene_expression of Mapk8 1 0.04 0 0.43
144 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
145 INT15024 Prkcg Regulation of Pdpk1 1 0.09 0 0.43
146 INT116931 OPRK1 Regulation of MAPK8 1 0.31 0.07 0.43
147 INT264475 Il1a Positive_regulation of Mapk8 1 0.04 0 0.43
148 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
149 INT196881 Ly6 Positive_regulation of Prkca 2 0.01 0.25 0.42
150 INT151184 Pdpk1 Positive_regulation of Trpv1 1 0.08 0 0.42
151 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
152 INT151183 Pdpk1 Positive_regulation of Phosphorylation of Trpv1 1 0.08 0 0.42
153 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
154 INT273111 Bdnf Positive_regulation of Positive_regulation of Mtor 1 0.44 0.07 0.42
155 INT116938 Positive_regulation of GLI2 Positive_regulation of MAPK8 1 0.10 0.07 0.41
156 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
157 INT319312 Socs4 Positive_regulation of Mapk8 1 0.05 0.68 0.41
158 INT319308 Socs4 Positive_regulation of Prkca 1 0.05 0.67 0.41
159 INT75489 Binding of SGCG and Tgfbr2 1 0.23 0.83 0.41
160 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
161 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
162 INT235860 Prkca Regulation of Akap5 1 0.16 0 0.39
163 INT236111 Binding of Pdpk1 and Ppara 1 0.26 1.21 0.39
164 INT306693 Prkca Regulation of Positive_regulation of Nav1 1 0.10 0.06 0.39
165 INT244046 Binding of Gabrg1 and Prkca 1 0.06 0 0.39
166 INT235880 Binding of Mtap2 and Prkaca 1 0.07 0.41 0.38
167 INT272751 EGFR Regulation of Negative_regulation of Prkca 1 0.01 0 0.38
168 INT272726 Mdk Regulation of Negative_regulation of Prkca 1 0.00 0 0.38
169 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
170 INT179938 Negative_regulation of Mapk8 Negative_regulation of TNF 1 0.02 1.09 0.37
171 INT187233 Positive_regulation of Mapk8 Positive_regulation of Jun 1 0.12 0.92 0.37
172 INT264480 Il1a Positive_regulation of Phosphorylation of Mapk8 1 0.04 0 0.37
173 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
174 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
175 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
176 INT207643 Prkca Positive_regulation of Mapk1 1 0.09 0.17 0.37
177 INT309120 Edc4 Negative_regulation of Positive_regulation of Mapk8 1 0.01 1.03 0.36
178 INT112617 Pdpk1 Regulation of Il1b 1 0.03 1.11 0.36
179 INT112618 Pdpk1 Regulation of Tnf 1 0.03 1.11 0.36
180 INT308653 Proc Regulation of Gene_expression of Mapk8 1 0.00 1.48 0.36
181 INT211492 Positive_regulation of GRIN1 Positive_regulation of Prkca 1 0.01 0.87 0.36
182 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
183 INT265145 Calm2 Negative_regulation of Phosphorylation of Adrbk1 1 0.05 0.07 0.35
184 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
185 INT253944 Positive_regulation of Prkca Positive_regulation of Gene_expression of Ins1 1 0.01 1.53 0.35
186 INT235859 Binding of Prkca and Akap5 1 0.13 0 0.35
187 INT330106 Racgap1 Positive_regulation of Positive_regulation of Mapk8 1 0.01 1.32 0.35
188 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
189 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
190 INT222721 Binding of HTR1A and Pdpk1 1 0.00 0.35 0.33
191 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
192 INT273118 Bdnf Positive_regulation of Mtor 1 0.66 0 0.33
193 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
194 INT284689 Binding of Tspo and Map3k12 1 0.00 0.59 0.32
195 INT348016 Binding of Mapk8 and Mapk8ip3 1 0.04 2.09 0.32
196 INT110461 Binding of Mapk8 and Gtf3a 1 0.03 0 0.32
197 INT106397 Positive_regulation of OPRL1 Positive_regulation of ADRBK1 1 0.46 0.09 0.31
198 INT102976 Binding of ADRBK1 and Rbm39 1 0.00 0 0.31
199 INT339645 Binding of Cdk5r1 and Ebi3 1 0.01 0.78 0.31
200 INT282421 Mapk8 Negative_regulation of Ins1 1 0.06 2.48 0.31

Single Events

The table below shows the top 100 pain related interactions that have been reported for peptidyl-threonine phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in peptidyl-threonine phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
2 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
3 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
4 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
5 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17
6 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
7 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95
8 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
9 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75
10 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
11 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
12 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
13 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
14 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
15 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25
16 INT117527 Binding of Prkca 25 0.48 6.43 21.05
17 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
18 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
19 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
20 INT48769 Regulation of Pdpk1 20 0.35 9.78 20.36
21 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
22 INT116950 Negative_regulation of MAPK8 103 0.57 44.48 17.53
23 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
24 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24
25 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86
26 INT109929 Phosphorylation of MAPK8 102 0.81 39.98 16.54
27 INT79458 Localization of Prkca 30 0.81 11.13 15.78
28 INT26733 Gene_expression of Pdpk1 17 0.48 5.74 13.91
29 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88
30 INT80685 Gene_expression of MAPK8 90 0.72 51.91 13.36
31 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
32 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
33 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65
34 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
35 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44
36 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
37 INT5630 Localization of Pdpk1 10 0.45 5.21 11.36
38 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
39 INT54706 Regulation of Adrbk1 11 0.62 0.89 10.69
40 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
41 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
42 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
43 INT145695 Regulation of Mapk8 26 0.62 14.67 9.83
44 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51
45 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
46 INT111998 Positive_regulation of Positive_regulation of Mapk8 23 0.69 9.33 8.97
47 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
48 INT104481 Regulation of Mapk8 21 0.50 13.87 8.41
49 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
50 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
51 INT96912 Positive_regulation of Phosphorylation of Mapk8 29 0.69 18.33 8.14
52 INT81345 Gene_expression of ADRBK1 21 0.70 2.89 7.9
53 INT104013 Negative_regulation of Gene_expression of Pdpk1 4 0.31 2.36 7.89
54 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
55 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
56 INT80686 Positive_regulation of Positive_regulation of MAPK8 42 0.68 26.95 7.63
57 INT99071 Positive_regulation of Gene_expression of Mapk8 16 0.55 9.87 7.58
58 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
59 INT98856 Negative_regulation of Gene_expression of Adrbk1 5 0.56 0.43 7.29
60 INT50779 Positive_regulation of Gene_expression of Adrbk1 9 0.56 2.79 7.23
61 INT71824 Phosphorylation of Pdpk1 14 0.38 4.9 6.86
62 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
63 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
64 INT161352 Gene_expression of Map3k12 3 0.24 0.59 6.16
65 INT55077 Positive_regulation of Positive_regulation of Pdpk1 6 0.26 1.77 5.78
66 INT123045 Negative_regulation of Phosphorylation of Prkca 9 0.46 5.73 5.77
67 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
68 INT68465 Positive_regulation of Gene_expression of Pdpk1 7 0.19 2.35 5.49
69 INT128922 Negative_regulation of Gene_expression of Mapk8 6 0.34 3.93 5.36
70 INT109928 Negative_regulation of Positive_regulation of MAPK8 19 0.42 10.42 5.23
71 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
72 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2
73 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19
74 INT135291 Positive_regulation of Positive_regulation of Mapk8 24 0.64 19.37 5.16
75 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
76 INT23611 Gene_expression of Mtor 23 0.66 3.57 5.02
77 INT131717 Positive_regulation of Gene_expression of Mapk8 18 0.55 14.25 5.02
78 INT57441 Positive_regulation of Phosphorylation of Prkca 9 0.40 2.72 4.89
79 INT83205 Negative_regulation of Negative_regulation of Prkca 6 0.43 1.14 4.87
80 INT64160 Negative_regulation of Gene_expression of Prkca 8 0.43 3.01 4.72
81 INT79460 Positive_regulation of Localization of Prkca 11 0.70 2.72 4.71
82 INT75629 Gene_expression of Mtap2 41 0.66 8.19 4.51
83 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
84 INT75523 Regulation of MAPK8 21 0.33 11.18 4.28
85 INT109219 Negative_regulation of Cdk5r1 5 0.43 1.22 4.25
86 INT109935 Positive_regulation of Phosphorylation of MAPK8 35 0.68 13.13 4.18
87 INT13190 Gene_expression of Pbk 10 0.31 1.97 4.14
88 INT1231 Negative_regulation of Positive_regulation of Pdpk1 6 0.35 1.88 4.13
89 INT110181 Negative_regulation of Phosphorylation of MAPK8 20 0.57 9.43 4.06
90 INT100741 Positive_regulation of ADRBK1 10 0.64 1.01 3.95
91 INT132103 Positive_regulation of Gene_expression of MAPK8 26 0.46 16.54 3.94
92 INT76466 Regulation of Gene_expression of Prkca 6 0.45 0.94 3.91
93 INT106972 Gene_expression of MAP2 36 0.75 9.72 3.87
94 INT118154 Positive_regulation of Binding of Prkca 2 0.50 0.58 3.81
95 INT75485 Gene_expression of Tgfbr2 10 0.57 10.98 3.76
96 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
97 INT154225 Negative_regulation of Binding of Prkca 2 0.30 0.06 3.71
98 INT83206 Regulation of Regulation of Prkca 3 0.45 1.34 3.46
99 INT21569 Binding of Mapk8 8 0.48 5.55 3.44
100 INT102516 Gene_expression of Map2 29 0.69 6.73 3.41
101 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
102 INT118153 Regulation of Positive_regulation of Prkca 5 0.45 3.15 3.23
103 INT163529 Negative_regulation of Positive_regulation of Mapk8 14 0.43 8.37 3.2
104 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
105 INT59288 Negative_regulation of Map2 12 0.59 6.2 3.19
106 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
107 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
108 INT54709 Positive_regulation of Gene_expression of Adrbk1 6 0.49 0.18 3.12
109 INT190860 Regulation of Localization of Prkca 4 0.21 1.61 3.11
110 INT105840 Regulation of Gene_expression of Adrbk1 2 0.44 0.16 3.09
111 INT105884 Binding of Bcl2 19 0.35 15.67 3
112 INT110755 Negative_regulation of Positive_regulation of Mapk8 15 0.46 9.91 2.98
113 INT102969 Positive_regulation of Gene_expression of ADRBK1 7 0.46 1.21 2.87
114 INT99592 Regulation of Adrbk1 3 0.61 1.46 2.84
115 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83
116 INT228678 Phosphorylation of Mtor 15 0.78 3.18 2.76
117 INT201632 Positive_regulation of Cdk5r1 20 0.40 21.6 2.75
118 INT47846 Negative_regulation of Localization of Pdpk1 2 0.33 1.12 2.75
119 INT95105 Gene_expression of TGFBR2 15 0.64 16.36 2.74
120 INT95735 Regulation of Phosphorylation of Mapk8 7 0.50 1.88 2.69
121 INT110503 Negative_regulation of ADRBK1 4 0.53 0.71 2.69
122 INT96763 Positive_regulation of Localization of Pdpk1 1 0.39 2.08 2.65
123 INT95739 Negative_regulation of Phosphorylation of Mapk8 11 0.42 6.77 2.61
124 INT184583 Regulation of Phosphorylation of Prkca 3 0.21 1.76 2.5
125 INT35390 Phosphorylation of Map2 12 0.81 2.06 2.47
126 INT94978 Negative_regulation of Adrbk1 6 0.38 0.13 2.47
127 INT101603 Positive_regulation of Cdk5r1 4 0.56 1.12 2.35
128 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
129 INT13188 Negative_regulation of Gene_expression of Pbk 1 0.10 0 2.27
130 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
131 INT72842 Phosphorylation of Adrbk1 5 0.47 0.58 2.16
132 INT109908 Localization of MAPK8 10 0.73 3.86 2.14
133 INT146491 Binding of Adrbk1 3 0.48 1.58 2.09
134 INT156270 Regulation of Positive_regulation of Mapk8 3 0.41 2.31 2.08
135 INT55470 Regulation of Mtor 16 0.24 12.51 2.07
136 INT36293 Gene_expression of Mtor 24 0.25 14.5 2.04
137 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
138 INT152696 Negative_regulation of Negative_regulation of Mapk8 1 0.32 0.35 2
139 INT109313 Binding of Mapk8 6 0.48 1.78 1.98
140 INT96916 Negative_regulation of Phosphorylation of Mapk8 16 0.52 9.68 1.97
141 INT102866 Regulation of Negative_regulation of Prkca 2 0.43 1.27 1.95
142 INT71569 Protein_catabolism of Map2 4 1.00 2.8 1.92
143 INT85359 Negative_regulation of Map3k12 6 0.51 0.07 1.89
144 INT170345 Negative_regulation of Localization of Prkca 5 0.23 0.88 1.88
145 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
146 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
147 INT102970 Localization of ADRBK1 4 0.66 0.45 1.85
148 INT26735 Regulation of Gene_expression of Pdpk1 2 0.24 0.56 1.84
149 INT164864 Positive_regulation of Negative_regulation of Mapk8 1 0.31 1.33 1.82
150 INT115850 Localization of Mtap2 10 0.73 3.68 1.76
151 INT299365 Transcription of Mapk8 9 0.72 5.91 1.75
152 INT104014 Negative_regulation of Phosphorylation of Pdpk1 2 0.23 0.59 1.72
153 INT151323 Positive_regulation of MAP2 7 0.50 1.36 1.71
154 INT245656 Positive_regulation of Gene_expression of Mtap2 4 0.37 3.5 1.71
155 INT149944 Positive_regulation of Phosphorylation of Map2 7 0.69 1.09 1.68
156 INT101599 Gene_expression of Cdk5r1 5 0.63 1.27 1.68
157 INT281639 Binding of Map3k12 2 0.02 3.05 1.68
158 INT73870 Positive_regulation of Regulation of Adrbk1 1 0.47 0.17 1.66
159 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
160 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
161 INT168714 Negative_regulation of Binding of Mapk8 1 0.36 0.18 1.62
162 INT94965 Transcription of Adrbk1 2 0.22 0.13 1.52
163 INT129436 Negative_regulation of Hk1 1 0.48 1.02 1.52
164 INT135033 Localization of Hk1 1 0.65 0.16 1.51
165 INT101601 Regulation of Cdk5r1 3 0.50 1.2 1.46
166 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44
167 INT109507 Regulation of Map3k12 2 0.54 0 1.43
168 INT166764 Localization of Mtor 2 0.75 1.28 1.42
169 INT67464 Positive_regulation of Negative_regulation of Pdpk1 1 0.19 0.15 1.41
170 INT73673 Negative_regulation of Mtap2 9 0.32 8.25 1.4
171 INT118927 Positive_regulation of Phosphorylation of Pdpk1 2 0.04 0.76 1.38
172 INT162284 Binding of Map2 3 0.29 1.78 1.35
173 INT114969 Gene_expression of CDK5R1 3 0.75 11.24 1.33
174 INT151216 Positive_regulation of Adrbk1 2 0.46 0.9 1.3
175 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
176 INT354377 Negative_regulation of Negative_regulation of Map3k12 1 0.10 0 1.27
177 INT125079 Negative_regulation of Gene_expression of MAPK8 9 0.39 4.87 1.25
178 INT221206 Phosphorylation of Pdpk1 3 0.53 0.13 1.25
179 INT354379 Negative_regulation of Gene_expression of Map3k12 1 0.12 0 1.24
180 INT354378 Regulation of Gene_expression of Map3k12 1 0.12 0 1.23
181 INT154048 Negative_regulation of Gene_expression of Mapk8 5 0.43 4.43 1.22
182 INT25389 Localization of Pbk 2 0.51 0.17 1.22
183 INT94967 Localization of Adrbk1 2 0.26 0.33 1.21
184 INT228671 Negative_regulation of Phosphorylation of Mtor 8 0.50 1.77 1.2
185 INT104011 Transcription of Pdpk1 1 0.28 0 1.2
186 INT104012 Regulation of Transcription of Pdpk1 1 0.14 0 1.2
187 INT26734 Binding of Pdpk1 4 0.29 1.01 1.19
188 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
189 INT69053 Regulation of Map2 3 0.27 2.3 1.17
190 INT138783 Positive_regulation of Gene_expression of Cdk5r1 2 0.38 0.68 1.15
191 INT108740 Localization of Map3k12 2 0.68 0.09 1.15
192 INT112931 Negative_regulation of Localization of Adrbk1 1 0.37 0 1.13
193 INT163914 Positive_regulation of Prkcd 1 0.67 1.43 1.12
194 INT112932 Localization of Adrbk1 1 0.69 0 1.12
195 INT203890 Positive_regulation of Gene_expression of Cdk5r1 9 0.40 9.13 1.11
196 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
197 INT70021 Localization of BCL2 23 0.74 21.6 1.09
198 INT106404 Positive_regulation of Positive_regulation of ADRBK1 2 0.41 0.31 1.08
199 INT135034 Binding of Hk1 1 0.32 0.09 1.07
200 INT98849 Binding of Adrbk1 3 0.36 0.18 1.04
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