GO:0018108

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Name peptidyl-tyrosine phosphorylation
Categary Process
Go Slim No
Go Link GO:0018108
Unique Molecular Interactions 1112
Total Molecular Interactions 1579
Total Single Events 10827
Pain Genes Associated 100

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for peptidyl-tyrosine phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for peptidyl-tyrosine phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT44716 Binding of ABL2 and PDYN 2 0.40 0.66 4.77
2 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
3 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
4 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
5 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
6 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
7 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
8 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
9 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
10 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
11 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
12 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 0.15 2.85 2.13
13 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
14 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
15 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
16 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
17 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
18 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
19 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
20 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
21 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
22 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
23 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
24 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14
25 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
26 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11
27 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
28 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
29 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
30 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
31 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
32 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99
33 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
34 INT137920 Binding of Kdr and Oprm1 1 0.23 0 0.97
35 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
36 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
37 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
38 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 0.09 0.18 0.93
39 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
40 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
41 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
42 INT121700 IL12RB1 Positive_regulation of Gene_expression of MMP1 1 0.06 0.22 0.9
43 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
44 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85
45 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85
46 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
47 INT183177 Binding of FGFR3 and NUDT6 1 0.06 1.08 0.84
48 INT110236 Hk1 Regulation of CSAD 1 0.01 1.57 0.84
49 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
50 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
51 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
52 INT99578 Binding of CEL and Kit 1 0.04 1.07 0.81
53 INT42797 Egf Regulation of Gene_expression of Penk 1 0.21 0.07 0.8
54 INT114068 Agtr2 Regulation of Gene_expression of Insr 1 0.15 0.95 0.79
55 INT151453 Gtf3a Regulation of Kit 1 0.04 0.25 0.78
56 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
57 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
58 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
59 INT231031 Egf Positive_regulation of Sec22b 1 0.03 0.05 0.76
60 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
61 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
62 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
63 INT133675 NPY6R Negative_regulation of SRC 1 0.17 0.75 0.74
64 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72
65 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
66 INT148453 Gene_expression of Inhbe Positive_regulation of Src 1 0.06 0.68 0.72
67 INT231751 Binding of Il2rg and Jak3 1 0.03 1.56 0.67
68 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
69 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65
70 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
71 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64
72 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
73 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64
74 INT126614 Ppyr1 Negative_regulation of Phosphorylation of Stat5a 1 0.27 0.1 0.64
75 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64
76 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64
77 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
78 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
79 INT126615 Binding of Oprd1 and Stat5a 1 0.28 0.07 0.61
80 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
81 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
82 INT56700 Penk Regulation of FER 1 0.00 0 0.59
83 INT202160 Binding of ARSD and CSF1R 1 0.16 1.69 0.59
84 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
85 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
86 INT260845 Binding of Flt1 and Positive_regulation of Gene_expression of TNF 1 0.36 1.5 0.56
87 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
88 INT355880 Il17a Regulation of Abi3 1 0.00 1.52 0.54
89 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53
90 INT231750 LOC690550 Negative_regulation of Jak3 1 0.02 1.3 0.52
91 INT249536 Binding of EPHA1 and Efnb2 1 0.02 0.28 0.52
92 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
93 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52
94 INT274938 Ltp Positive_regulation of Localization of Ephb2 1 0.25 0 0.52
95 INT114070 Agtr2 Positive_regulation of Gene_expression of Insr 1 0.13 0.34 0.52
96 INT184096 Il7 Positive_regulation of Stat5a 1 0.07 0.26 0.51
97 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
98 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51
99 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
100 INT210878 Binding of FLT1 and HBM 1 0.06 0.83 0.5
101 INT221630 Binding of Fes and Plxna1 1 0.01 1.02 0.5
102 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
103 INT98734 Egf Negative_regulation of Tk1 1 0.13 0.15 0.49
104 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
105 INT108329 EGF Positive_regulation of Phosphorylation of EPHB2 4 0.48 3.96 0.48
106 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48
107 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
108 INT321045 Anpep Positive_regulation of Protein_catabolism of Ptpn6 1 0.01 0.22 0.48
109 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
110 INT237154 LGALS4 Positive_regulation of KIT 1 0.10 1.99 0.47
111 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
112 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
113 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
114 INT151485 Negative_regulation of Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
115 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
116 INT151484 Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
117 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
118 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
119 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
120 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
121 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
122 INT116934 OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
123 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
124 INT116933 SRC Positive_regulation of JUN 1 0.33 0.15 0.46
125 INT116937 Positive_regulation of OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
126 INT117776 Binding of Ptk2 and Regulation of Phosphorylation of Ddr1 1 0.10 0.17 0.46
127 INT295406 Egf Regulation of Gene_expression of Oprk1 1 0.01 0.72 0.43
128 INT278950 MAPK8 Negative_regulation of Localization of EPHB2 1 0.25 0.47 0.43
129 INT278964 MAPK14 Negative_regulation of Localization of EPHB2 1 0.15 0.47 0.43
130 INT321047 Anpep Regulation of Negative_regulation of Ptpn6 1 0.01 0.25 0.43
131 INT13281 Egf Regulation of Ngf 1 0.66 0.12 0.42
132 INT303857 DDR1 Positive_regulation of IL8 1 0.05 1.5 0.42
133 INT303858 DDR1 Positive_regulation of CXCR2 1 0.11 1.5 0.42
134 INT13279 Ngf Regulation of Egf 1 0.49 0.12 0.42
135 INT13283 Egf Regulation of Fgf2 1 0.49 0.11 0.41
136 INT13284 Fgf2 Regulation of Egf 1 0.49 0.11 0.41
137 INT327727 Atp6v0a2 Negative_regulation of Gene_expression of Kit 1 0.05 0.83 0.41
138 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
139 INT114067 Ace Regulation of Insr 1 0.09 0.31 0.39
140 INT184092 Il11ra1 Positive_regulation of Jak1 1 0.17 0.3 0.39
141 INT234607 Socs3 Negative_regulation of JAK1 1 0.01 0.54 0.39
142 INT148246 Binding of KITLG and Positive_regulation of Kit 1 0.04 0.43 0.38
143 INT237369 SOAT1 Negative_regulation of Phosphorylation of JAK1 1 0.00 0 0.38
144 INT167946 Binding of SRC and Stat5b 1 0.28 0 0.38
145 INT283840 Binding of Egf and hb 1 0.21 1.34 0.38
146 INT263433 Abl1 Regulation of Abl1 1 0.04 0.28 0.38
147 INT328819 Binding of Il6 and Jak1 1 0.08 0 0.38
148 INT278957 JAK3 Positive_regulation of Gene_expression of IL8 1 0.28 0.67 0.38
149 INT148247 KITLG Positive_regulation of Kit 1 0.03 0.43 0.38
150 INT328822 Binding of Jak1 and TYK2 1 0.11 0 0.38
151 INT328821 Binding of Il6st and Jak1 1 0.05 0 0.38
152 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
153 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
154 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
155 INT303994 Il6 Positive_regulation of JAK2 1 0.03 0.41 0.37
156 INT278955 JAK3 Positive_regulation of Gene_expression of PRKCA 1 0.12 0.65 0.37
157 INT143917 Binding of Src and Arrb2 1 0.27 0.07 0.37
158 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
159 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
160 INT353390 Binding of DRD4 and SRC 1 0.25 0.62 0.37
161 INT274936 Ephb2 Regulation of Gene_expression of Fos 1 0.15 0 0.36
162 INT356274 Egf Positive_regulation of Localization of Stat3 1 0.13 0.22 0.36
163 INT274941 Ephb2 Regulation of Phosphorylation of Mapk1 1 0.19 0 0.36
164 INT295407 Egf Positive_regulation of Localization of Oprk1 1 0.02 0.67 0.36
165 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
166 INT143918 Binding of Src and Rbm39 1 0.02 0.07 0.36
167 INT336573 Ptpn2 Regulation of INSR 1 0.00 1.36 0.36
168 INT274937 Ephb2 Regulation of Phosphorylation of Creb1 1 0.21 0 0.36
169 INT274933 Ephb2 Regulation of Phosphorylation of Camk2a 1 0.29 0 0.36
170 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
171 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
172 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
173 INT263383 Abl1 Regulation of Trib3 1 0.01 0.28 0.35
174 INT242403 INSR Positive_regulation of Gene_expression of Bdkrb1 1 0.45 0.88 0.35
175 INT148240 Binding of Kit and Ret 1 0.24 0.44 0.35
176 INT94875 Binding of Calca and Egf 1 0.25 0 0.35
177 INT148241 Binding of Kit and Ntrk1 1 0.25 0.44 0.35
178 INT337156 Kdr Positive_regulation of Gtf3a 1 0.01 0.77 0.35
179 INT263382 Src Regulation of Trib3 1 0.00 0.29 0.35
180 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
181 INT181453 Gene_expression of Ccl2 Positive_regulation of Gene_expression of Il12rb1 1 0.06 1.87 0.34
182 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34
183 INT254213 Binding of Jak1 and Tyk2 1 0.09 0.84 0.33
184 INT181896 TNF Regulation of TEK 1 0.03 1.21 0.33
185 INT254209 Jak1 Positive_regulation of Stat3 1 0.18 0.84 0.33
186 INT249490 Phosphorylation of Ephb2 Positive_regulation of Src 1 0.17 0.15 0.33
187 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
188 INT184110 Jak1 Positive_regulation of Stat1 1 0.32 0.3 0.33
189 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
190 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
191 INT249480 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Src 1 0.22 0.23 0.31
192 INT75769 Egf Positive_regulation of Cpox 1 0.26 0.76 0.31
193 INT257739 SAGE1 Positive_regulation of DDR1 1 0.00 0.91 0.31
194 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3
195 INT170496 Egf Positive_regulation of Mapk1 3 0.21 0.5 0.3
196 INT7417 Calca Positive_regulation of Localization of FGFR3 1 0.03 0.09 0.3
197 INT356288 Egf Positive_regulation of Trib3 1 0.00 0.17 0.3
198 INT7405 CALCA Negative_regulation of FGFR3 1 0.00 0.1 0.3
199 INT148242 Binding of Kit and Gtf3a 1 0.04 0.34 0.3
200 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3

Single Events

The table below shows the top 100 pain related interactions that have been reported for peptidyl-tyrosine phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in peptidyl-tyrosine phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
2 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
3 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
4 INT8691 Localization of Insr 85 0.80 9.27 30.32
5 INT5300 Regulation of Insr 54 0.60 11.33 29.26
6 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67
7 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
8 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
9 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99
10 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
11 INT7411 Localization of FGFR3 40 0.78 4.77 10.24
12 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09
13 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42
14 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
15 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95
16 INT22771 Positive_regulation of Egf 44 0.70 16.45 8.64
17 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
18 INT87650 Positive_regulation of EPHB2 49 0.67 22.77 8.25
19 INT108336 Phosphorylation of EPHB2 41 0.80 22.25 8.21
20 INT18736 Gene_expression of Ptpn6 19 0.59 4.44 8.06
21 INT76892 Gene_expression of FGFR1 45 0.69 23.6 7.56
22 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41
23 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
24 INT9491 Positive_regulation of Ptpn6 11 0.51 2.33 7.32
25 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27
26 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27
27 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
28 INT145299 Negative_regulation of Jak3 25 0.48 17.66 7.13
29 INT125143 Gene_expression of EPHB2 40 0.71 13.27 6.97
30 INT150287 Positive_regulation of Ephb2 5 0.33 5.54 6.9
31 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
32 INT13822 Localization of Egf 30 0.81 13.79 6.4
33 INT64052 Positive_regulation of FGFR1 26 0.52 28.47 6.36
34 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
35 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
36 INT50975 Localization of Ptpn6 8 0.65 2.64 5.7
37 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
38 INT152433 Binding of CSF1R 6 0.33 10.97 5.54
39 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47
40 INT100222 Binding of Src 9 0.26 5.41 5.37
41 INT213741 Gene_expression of Kdr 60 0.75 44.24 5.35
42 INT21901 Negative_regulation of Egf 25 0.58 10.46 4.99
43 INT114058 Negative_regulation of Gene_expression of Insr 13 0.31 9.23 4.97
44 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
45 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
46 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
47 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84
48 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
49 INT98453 Positive_regulation of Src 19 0.47 7.84 4.62
50 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
51 INT97903 Negative_regulation of FGFR1 16 0.17 5.6 4.57
52 INT108342 Negative_regulation of EPHB2 18 0.57 9.48 4.46
53 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38
54 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
55 INT126608 Binding of Stat5a 7 0.48 0.46 4.38
56 INT28734 Gene_expression of Reln 7 0.74 5.76 4.33
57 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
58 INT51084 Binding of Insr 13 0.30 4.25 4.23
59 INT65926 Positive_regulation of Gene_expression of Egf 26 0.70 12.91 4.18
60 INT88278 Binding of Kit 33 0.37 24.45 4.13
61 INT23653 Binding of Egf 22 0.36 11.34 4.12
62 INT83035 Binding of INSR 16 0.47 9.29 4.11
63 INT100372 Gene_expression of Flt1 47 0.71 24.33 4.09
64 INT158573 Negative_regulation of Jak3 3 0.43 8.2 3.99
65 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
66 INT152254 Gene_expression of CSF1R 16 0.75 12.93 3.81
67 INT229912 Phosphorylation of Fyn 5 0.42 2.57 3.78
68 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
69 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
70 INT109391 Gene_expression of Fgfr1 7 0.56 1.78 3.67
71 INT31758 Positive_regulation of Egf 32 0.66 19.42 3.64
72 INT328808 Negative_regulation of Jak1 1 0.42 7.01 3.64
73 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61
74 INT122327 Regulation of Src 6 0.59 0.59 3.6
75 INT18920 Binding of Egf 24 0.48 9.43 3.57
76 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
77 INT10116 Localization of INSR 11 0.57 5.43 3.48
78 INT6339 Negative_regulation of Ptpn6 6 0.14 0.71 3.44
79 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
80 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
81 INT7408 Negative_regulation of FGFR3 12 0.43 2.38 3.33
82 INT137350 Phosphorylation of Src 13 0.45 4.14 3.32
83 INT118035 Positive_regulation of JAK1 23 0.67 10.57 3.29
84 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
85 INT64 Regulation of Ptpn6 12 0.14 2.45 3.17
86 INT124736 Positive_regulation of Gene_expression of Insr 6 0.31 7.55 3.12
87 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09
88 INT100688 Gene_expression of SRC 28 0.75 15.51 3.08
89 INT145298 Gene_expression of Jak3 5 0.78 7.69 3.07
90 INT91890 Positive_regulation of Kit 36 0.50 25.44 3.06
91 INT119218 Positive_regulation of Fgfr1 4 0.58 1.11 3.05
92 INT137907 Phosphorylation of Ephb2 2 0.61 2.78 2.96
93 INT31757 Negative_regulation of Egf 18 0.41 9.7 2.94
94 INT177993 Localization of CSF1R 4 0.73 7.49 2.94
95 INT108338 Positive_regulation of Phosphorylation of EPHB2 13 0.67 5.42 2.92
96 INT7409 Negative_regulation of Localization of FGFR3 12 0.37 2.24 2.92
97 INT53733 Positive_regulation of FGFR3 6 0.45 1.32 2.76
98 INT161310 Negative_regulation of LCK 17 0.42 8.75 2.74
99 INT150286 Gene_expression of Ephb2 3 0.39 2.57 2.74
100 INT178002 Positive_regulation of CSF1R 2 0.37 6.52 2.74
101 INT321018 Protein_catabolism of Ptpn6 1 0.14 0.52 2.73
102 INT225253 Positive_regulation of Phosphorylation of Src 4 0.38 2.36 2.59
103 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
104 INT142908 Localization of FGFR1 18 0.38 11.46 2.57
105 INT28878 Negative_regulation of Localization of Egf 6 0.49 10.34 2.57
106 INT77636 Phosphorylation of Egf 11 0.61 1.69 2.56
107 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
108 INT126610 Phosphorylation of Stat5a 5 0.82 0.8 2.52
109 INT23527 Negative_regulation of Localization of Insr 10 0.39 2.58 2.5
110 INT137908 Phosphorylation of Pdgfrb 14 0.81 8.44 2.45
111 INT130476 Phosphorylation of Fyn 8 0.80 2.99 2.44
112 INT113339 Binding of JAK2 6 0.40 5.31 2.4
113 INT192337 Positive_regulation of DDR1 11 0.41 10.34 2.38
114 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
115 INT7410 Positive_regulation of Localization of FGFR3 9 0.45 1.97 2.36
116 INT134626 Positive_regulation of Gene_expression of Kdr 20 0.63 14.63 2.29
117 INT29402 Gene_expression of Src 16 0.74 4.57 2.29
118 INT17617 Gene_expression of ABL2 8 0.75 2.73 2.25
119 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
120 INT153411 Positive_regulation of Jak1 3 0.49 1.24 2.25
121 INT151449 Negative_regulation of Gene_expression of Kit 18 0.45 12.05 2.23
122 INT36314 Gene_expression of FGFR3 11 0.73 6.21 2.23
123 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2
124 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19
125 INT24621 Regulation of Gene_expression of Insr 9 0.42 2.68 2.18
126 INT85085 Positive_regulation of KIT 36 0.53 30.08 2.17
127 INT183159 Gene_expression of Epha1 3 0.25 3.15 2.17
128 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
129 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15
130 INT137629 Binding of Ptpn6 10 0.30 0.42 2.15
131 INT321023 Positive_regulation of Localization of Ptpn6 1 0.07 0.27 2.15
132 INT122671 Positive_regulation of LCK 4 0.13 2.69 2.14
133 INT145297 Positive_regulation of Jak3 3 0.50 5.52 2.14
134 INT116077 Positive_regulation of Positive_regulation of EPHB2 4 0.67 2.32 2.13
135 INT278340 Gene_expression of Syk 7 0.51 4.92 2.09
136 INT31006 Regulation of Localization of Insr 7 0.50 0.2 2.05
137 INT100371 Positive_regulation of Flt1 11 0.63 6.42 2.02
138 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
139 INT99572 Localization of Kit 13 0.75 5.23 1.95
140 INT134628 Gene_expression of Flt4 9 0.48 7.52 1.94
141 INT137906 Positive_regulation of Phosphorylation of Pdgfrb 6 0.50 2.55 1.94
142 INT143127 Positive_regulation of FLT1 44 0.66 21.7 1.92
143 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92
144 INT249530 Positive_regulation of Positive_regulation of Src 3 0.28 1.32 1.9
145 INT153719 Gene_expression of TEK 10 0.49 9.82 1.88
146 INT114059 Localization of Insr 10 0.46 3.49 1.87
147 INT100689 Negative_regulation of JAK1 8 0.57 5.36 1.87
148 INT189839 Gene_expression of Jak1 2 0.50 0.51 1.87
149 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86
150 INT98464 Positive_regulation of Positive_regulation of SRC 10 0.67 5.71 1.86
151 INT83596 Gene_expression of Ptk2 6 0.76 2.22 1.84
152 INT265064 Binding of Reln 1 0.02 2.7 1.83
153 INT44723 Positive_regulation of ABL2 7 0.49 2.23 1.82
154 INT172961 Localization of Egf 26 0.71 16.74 1.81
155 INT73721 Negative_regulation of Gene_expression of Egf 5 0.43 2.28 1.8
156 INT140175 Regulation of Kit 23 0.62 8.59 1.79
157 INT162725 Binding of Kdr 13 0.42 8.86 1.79
158 INT126609 Positive_regulation of Phosphorylation of Stat5a 1 0.69 0.26 1.79
159 INT154515 Localization of Ephb2 2 0.73 0.17 1.77
160 INT218303 Protein_catabolism of INSR 3 0.29 0.67 1.73
161 INT265066 Positive_regulation of Reln 1 0.02 1.59 1.72
162 INT232645 Transcription of INSR 2 0.09 1.19 1.71
163 INT82609 Phosphorylation of SRC 17 0.80 6.45 1.7
164 INT28735 Localization of Reln 2 0.12 1.49 1.7
165 INT278981 Negative_regulation of JAK3 5 0.46 2.12 1.69
166 INT19747 Regulation of Egf 14 0.46 4.67 1.68
167 INT263398 Positive_regulation of Abl1 1 0.60 1.44 1.66
168 INT146943 Gene_expression of Src 13 0.49 6.65 1.65
169 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
170 INT255663 Binding of Flt1 11 0.32 6.92 1.64
171 INT206144 Phosphorylation of JAK1 6 0.57 1.77 1.64
172 INT206471 Positive_regulation of Ptk2 34 0.51 25.75 1.61
173 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
174 INT98476 Gene_expression of Ddr1 3 0.58 1.28 1.6
175 INT103767 Phosphorylation of DDR1 6 0.20 4.67 1.56
176 INT114061 Regulation of Gene_expression of Insr 4 0.27 2.03 1.56
177 INT19342 Regulation of Insr 12 0.24 6.11 1.54
178 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
179 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
180 INT129436 Negative_regulation of Hk1 1 0.48 1.02 1.52
181 INT221560 Gene_expression of Fes 36 0.72 6.63 1.51
182 INT135033 Localization of Hk1 1 0.65 0.16 1.51
183 INT114525 Negative_regulation of Positive_regulation of Egf 4 0.35 2.93 1.5
184 INT106574 Phosphorylation of Jak1 2 0.60 0.35 1.5
185 INT74528 Negative_regulation of PDGFB 11 0.40 10.34 1.48
186 INT98455 Regulation of Src 4 0.20 1.76 1.48
187 INT74530 Transcription of PDGFB 7 0.65 4.56 1.47
188 INT29856 Negative_regulation of Positive_regulation of Ptpn6 3 0.38 1.24 1.47
189 INT53735 Regulation of FGFR3 4 0.26 0.76 1.45
190 INT122672 Regulation of Positive_regulation of LCK 1 0.06 1.15 1.44
191 INT151450 Positive_regulation of Gene_expression of Kit 23 0.69 13.11 1.43
192 INT237409 Localization of Erbb4 3 0.57 1.31 1.41
193 INT159312 Regulation of Reln 4 0.43 1.79 1.4
194 INT224501 Positive_regulation of Gene_expression of EPHB2 9 0.49 4.29 1.39
195 INT199550 Negative_regulation of Flt1 18 0.37 12.57 1.37
196 INT100373 Negative_regulation of Gene_expression of Flt1 11 0.53 10 1.37
197 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
198 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
199 INT199567 Binding of Kdr 18 0.47 13.81 1.34
200 INT131115 Regulation of Phosphorylation of Ptk2 2 0.61 0.3 1.34
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