GO:0018298

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Name protein-chromophore linkage
Categary Process
Go Slim No
Go Link GO:0018298
Unique Molecular Interactions 45
Total Molecular Interactions 53
Total Single Events 675
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein-chromophore linkage. They are ordered first by their pain relevance and then by number of times they were reported for protein-chromophore linkage. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT351246 Binding of OPN1LW and NNT 1 0.03 0.53 1.45
2 INT351245 Binding of TNC and OPN1LW 1 0.03 0.89 1.31
3 INT167618 Rho Regulation of App 1 0.17 0.88 0.55
4 INT129640 Binding of Ambp and Oprd1 1 0.22 0.19 0.55
5 INT129639 Regulation of Binding of Ambp and Oprd1 1 0.17 0.19 0.55
6 INT193502 Binding of OPN1SW and CECR 1 0.02 0.49 0.33
7 INT312573 AMBP Negative_regulation of IL6 1 0.11 1.41 0.32
8 INT312571 AMBP Negative_regulation of Positive_regulation of IL6 1 0.11 1.41 0.32
9 INT15828 Ambp Regulation of Negative_regulation of Fn1 1 0.03 0 0.3
10 INT15829 Ambp Regulation of Positive_regulation of ELANE 1 0.00 0 0.24
11 INT336738 S100a8 Regulation of Gene_expression of Ambp 1 0.02 2.15 0.24
12 INT98410 Binding of AMBP and Rf 1 0.02 0.95 0.22
13 INT21453 Ambp Regulation of ELANE 1 0.00 0 0.15
14 INT312572 AMBP Negative_regulation of Gene_expression of IL6 1 0.11 0.66 0.14
15 INT310626 Ambp Regulation of OTOR 1 0.15 1.04 0.14
16 INT347065 Binding of Gnat2 and Rho 1 0.14 0 0.12
17 INT312568 AMBP Regulation of Negative_regulation of PRSS1 1 0.02 0.95 0.12
18 INT312570 AMBP Regulation of Negative_regulation of ELANE 1 0.06 0.95 0.12
19 INT336740 Positive_regulation of Ambp Positive_regulation of Gene_expression of S100a8 1 0.02 1.3 0.12
20 INT276438 Binding of OPN1SW and MYP1 1 0.12 1.21 0.09
21 INT188964 Binding of AMBP and NAGLU 1 0.01 1.27 0.09
22 INT21452 Ambp Regulation of Gene_expression of ELANE 1 0.00 0 0.08
23 INT56377 AMBP Negative_regulation of Elane 1 0.00 1.43 0.08
24 INT21446 Ambp Negative_regulation of Positive_regulation of Mpo 1 0.01 0 0.07
25 INT159853 Gene_expression of IL2 Regulation of Gene_expression of RHO 1 0.17 0.16 0.07
26 INT225064 Binding of IGHA1 and IGHG3 1 0.01 1.54 0.07
27 INT346523 Binding of PTH1R and RHO 1 0.01 0 0.05
28 INT191590 Binding of AMBP and Arsb 1 0.00 1.82 0.04
29 INT268710 Binding of RHO and ERLEC1 1 0.00 0.71 0.03
30 INT226714 Binding of Ambp and Hivan1 1 0.00 0.32 0
31 INT336537 Binding of Clock and Cry2 1 0.32 0 0
32 INT197813 Binding of AMBP and MEN1 1 0.00 0.51 0
33 INT197812 Binding of AMBP and RDBP 1 0.00 0.51 0
34 INT270316 Binding of AMBP and NHS 1 0.20 0.91 0
35 INT259050 Binding of HPV18I1 and OPN1LW 1 0.01 1.19 0
36 INT217915 Binding of Cry1 and Per2 1 0.28 0 0
37 INT336536 Binding of Arntl and Cry1 1 0.37 0 0
38 INT226711 Binding of Ambp and Tsg101 1 0.01 0.33 0
39 INT262752 IGHA1 Positive_regulation of IGKV2D-19 1 0.00 1.39 0
40 INT53286 Binding of CYP1A2 and OPN1LW 1 0.03 0 0
41 INT285042 Dbi Regulation of Gene_expression of Rho 1 0.01 0 0
42 INT336533 Binding of Clock and Cry1 1 0.32 0 0
43 INT285047 WTS Regulation of Gene_expression of Rho 1 0.02 0 0
44 INT311764 Opn4 Regulation of Mrgprc1-ps 1 0.43 0 0
45 INT336534 Binding of Arntl and Cry2 1 0.37 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein-chromophore linkage. They are ordered first by their pain relevance and then by number of times they were reported in protein-chromophore linkage. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT53290 Gene_expression of OPN1LW 5 0.31 6.9 9.15
2 INT53288 Binding of OPN1LW 5 0.11 4.24 8.9
3 INT56374 Gene_expression of AMBP 34 0.54 35.85 6.25
4 INT2072 Localization of AMBP 33 0.65 37.58 4.84
5 INT164220 Gene_expression of OPN1SW 21 0.65 13.7 4.14
6 INT181589 Binding of OPN1SW 13 0.32 9.47 4.07
7 INT181588 Regulation of OPN1SW 14 0.39 8.32 3.59
8 INT120372 Positive_regulation of Ambp 21 0.21 21.1 2.66
9 INT56376 Negative_regulation of AMBP 29 0.35 21.49 2.59
10 INT19430 Positive_regulation of IGHA1 10 0.67 6.42 2.58
11 INT160673 Gene_expression of Ambp 16 0.49 19.49 2.3
12 INT56375 Positive_regulation of AMBP 25 0.60 21.24 2.22
13 INT113439 Positive_regulation of OPN1LW 2 0.11 0.84 2.01
14 INT186134 Binding of IGHA1 5 0.01 4.71 1.99
15 INT82918 Binding of AMBP 23 0.39 23.31 1.71
16 INT193504 Positive_regulation of OPN1SW 11 0.58 7.44 1.47
17 INT128322 Gene_expression of Cry1 11 0.60 1.03 1.4
18 INT169776 Gene_expression of Opn4 52 0.77 8.75 1.38
19 INT128321 Regulation of Gene_expression of Cry1 2 0.34 0.09 1.38
20 INT11984 Gene_expression of IGHA1 9 0.54 6.12 1.35
21 INT126535 Negative_regulation of RHO 4 0.57 1.48 1.32
22 INT351255 Transcription of OPN1LW 1 0.16 1.15 1.27
23 INT146200 Positive_regulation of Rho 20 0.45 2.1 1.23
24 INT351256 Regulation of OPN1LW 1 0.10 0.55 1.17
25 INT256412 Negative_regulation of Localization of AMBP 1 0.04 6.09 1.14
26 INT322086 Regulation of Regulation of OPN1SW 1 0.02 2.68 1.12
27 INT53291 Negative_regulation of Binding of OPN1LW 2 0.10 0.67 1.02
28 INT184882 Regulation of AMBP 5 0.34 3.3 0.94
29 INT181587 Negative_regulation of OPN1SW 12 0.51 4.36 0.89
30 INT17804 Negative_regulation of Ambp 2 0.31 2.03 0.85
31 INT11983 Regulation of IGHA1 3 0.12 1.88 0.82
32 INT225056 Positive_regulation of Gene_expression of AMBP 4 0.37 5.45 0.75
33 INT256411 Phosphorylation of AMBP 1 0.08 10.3 0.73
34 INT200750 Gene_expression of Rho 19 0.65 6.52 0.69
35 INT128314 Gene_expression of Cry2 2 0.46 0.18 0.68
36 INT128326 Regulation of Gene_expression of Cry2 1 0.03 0.09 0.68
37 INT225059 Positive_regulation of Regulation of OPN1SW 1 0.40 1.14 0.67
38 INT211782 Localization of Ambp 2 0.26 2.12 0.64
39 INT169778 Positive_regulation of Opn4 8 0.68 1.63 0.63
40 INT104069 Regulation of RHO 4 0.60 1.68 0.57
41 INT28131 Regulation of Rho 2 0.62 0.5 0.42
42 INT188967 Negative_regulation of Binding of AMBP 2 0.03 2.7 0.39
43 INT144617 Gene_expression of RHO 13 0.75 1.74 0.38
44 INT159856 Positive_regulation of RHO 5 0.67 0.94 0.37
45 INT114313 Binding of RHO 7 0.36 1.45 0.36
46 INT217889 Binding of Cry1 4 0.32 0 0.33
47 INT57902 Localization of RHO 3 0.36 0.77 0.31
48 INT204799 Binding of Rho 2 0.12 1.2 0.3
49 INT74136 Localization of IGHA1 1 0.63 0.54 0.3
50 INT304999 Localization of OPN1SW 1 0.57 0.36 0.22
51 INT256413 Positive_regulation of Localization of AMBP 1 0.05 0.68 0.21
52 INT93087 Negative_regulation of Rho 1 0.59 0 0.2
53 INT76126 Transcription of IGHA1 1 0.05 0.08 0.18
54 INT246103 Negative_regulation of Gene_expression of OPN1SW 1 0.36 1.26 0.15
55 INT245360 Positive_regulation of Gene_expression of Rho 5 0.49 0.37 0.14
56 INT193503 Positive_regulation of Positive_regulation of OPN1SW 1 0.32 0.27 0.14
57 INT304880 Protein_catabolism of Rho 1 0.47 1.01 0.14
58 INT169775 Positive_regulation of Positive_regulation of Opn4 1 0.49 0.12 0.13
59 INT336732 Transcription of Ambp 1 0.03 1.17 0.13
60 INT336733 Positive_regulation of Gene_expression of Ambp 1 0.02 1.1 0.12
61 INT328643 Binding of Rho 2 0.16 0.08 0.11
62 INT217884 Transcription of Cry1 9 0.55 1.82 0.1
63 INT217566 Transcription of Rho 1 0.22 0.1 0.1
64 INT243453 Negative_regulation of Opn4 13 0.50 2.37 0.09
65 INT204236 Gene_expression of Rho 3 0.23 1.26 0.09
66 INT271380 Regulation of Cry1 2 0.25 0.59 0.09
67 INT264282 Positive_regulation of Gene_expression of Opn4 3 0.50 0.25 0.08
68 INT332857 Binding of Cry2 2 0.32 0 0.08
69 INT332841 Negative_regulation of Binding of Cry1 1 0.29 0 0.08
70 INT332843 Negative_regulation of Binding of Cry2 1 0.33 0 0.08
71 INT233814 Positive_regulation of Gene_expression of RHO 1 0.29 0 0.08
72 INT141149 Localization of OPN1LW 1 0.01 0.38 0.07
73 INT274112 Regulation of Phosphorylation of Rho 1 0.17 0.73 0.07
74 INT274111 Phosphorylation of Rho 1 0.39 0.73 0.07
75 INT248969 Transcription of Cry2 2 0.59 0.56 0.06
76 INT93089 Positive_regulation of Rho 3 0.47 1.17 0.05
77 INT192757 Regulation of Gene_expression of RHO 1 0.22 0.1 0.05
78 INT318708 Transcription of OPN1SW 1 0.01 0.28 0.05
79 INT273458 Regulation of Rho 3 0.36 0.07 0.04
80 INT217887 Regulation of Transcription of Cry1 2 0.46 0.06 0.04
81 INT290790 Phosphorylation of Cry2 1 0.46 0.29 0.04
82 INT290783 Protein_catabolism of Cry2 1 0.48 0.19 0.04
83 INT290799 Positive_regulation of Protein_catabolism of Cry2 1 0.34 0.19 0.04
84 INT224192 Negative_regulation of Gene_expression of RHO 1 0.12 0.09 0.04
85 INT278909 Regulation of Gene_expression of Rho 2 0.27 0 0.03
86 INT240992 Negative_regulation of Rho 6 0.20 2.58 0
87 INT217890 Positive_regulation of Transcription of Cry1 2 0.38 0.49 0
88 INT285039 Positive_regulation of Positive_regulation of Rho 2 0.26 0.06 0
89 INT241015 Negative_regulation of Negative_regulation of Rho 2 0.20 2.31 0
90 INT278914 Negative_regulation of Positive_regulation of Rho 1 0.09 0 0
91 INT311757 Localization of Opn4 1 0.64 0 0
92 INT188073 Transcription of RHO 1 0.52 0.39 0
93 INT204801 Regulation of Positive_regulation of Rho 1 0.13 1.25 0
94 INT256648 Negative_regulation of Gene_expression of AMBP 1 0.02 0.59 0
95 INT348925 Positive_regulation of Binding of OPN1SW 1 0.43 1.57 0
96 INT217882 Protein_catabolism of Cry1 1 0.75 0 0
97 INT217885 Positive_regulation of Cry1 1 0.30 0 0
98 INT300158 Negative_regulation of Transcription of Cry2 1 0.25 0.13 0
99 INT243454 Regulation of Gene_expression of Opn4 1 0.23 0.25 0
100 INT93088 Localization of Rho 1 0.75 0 0
101 INT311762 Regulation of Opn4 1 0.27 0.19 0
102 INT217892 Negative_regulation of Gene_expression of Cry1 1 0.32 0 0
103 INT204803 Regulation of Binding of Rho 1 0.13 1.15 0
104 INT300160 Negative_regulation of Cry2 1 0.25 0.13 0
105 INT217880 Localization of Cry1 1 0.60 0 0
106 INT311759 Negative_regulation of Transcription of Opn4 1 0.37 0.15 0
107 INT204802 Positive_regulation of Binding of Rho 1 0.15 1.24 0
108 INT243452 Negative_regulation of Gene_expression of Opn4 1 0.36 0.26 0
109 INT347091 Binding of Opn4 1 0.37 0.48 0
110 INT204797 Positive_regulation of Gene_expression of Rho 1 0.14 1.11 0
111 INT311761 Transcription of Opn4 1 0.59 0.16 0
112 INT192747 Positive_regulation of Positive_regulation of RHO 1 0.24 0.14 0
113 INT204014 Phosphorylation of Cry1 1 0.01 0.16 0
114 INT328648 Negative_regulation of Gene_expression of Rho 1 0.19 0.54 0
115 INT278926 Regulation of Positive_regulation of Rho 1 0.10 0 0
116 INT292831 Positive_regulation of Gene_expression of Cry1 1 0.54 0 0
117 INT294700 Positive_regulation of Negative_regulation of OPN1SW 1 0.13 0 0
118 INT217883 Positive_regulation of Localization of Cry1 1 0.38 0 0
119 INT347056 Localization of Rho 1 0.30 0.06 0
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