GO:0019079

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Name viral genome replication
Categary Process
Go Slim No
Go Link GO:0019079
Unique Molecular Interactions 131
Total Molecular Interactions 194
Total Single Events 1644
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for viral genome replication. They are ordered first by their pain relevance and then by number of times they were reported for viral genome replication. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT51205 Binding of OPRK1 and PDYN 7 0.00 2.01 7.8
2 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
3 INT51202 Positive_regulation of Binding of OPRK1 and PDYN 3 0.00 0.63 3.1
4 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
5 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
6 INT133946 Binding of DNM2 and OPRK1 1 0.11 0 2.1
7 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
8 INT133937 Binding of OPRK1 and ARFGEF1 1 0.01 0 1.39
9 INT51203 Binding of OPRK1 and OPRM1 2 0.29 0.3 1.36
10 INT67383 Binding of OPRK1 and Pdyn 2 0.00 0 1.25
11 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
12 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
13 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
14 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
15 INT108413 Binding of OPRK1 and Oprd1 1 0.00 0.08 1.04
16 INT51204 Positive_regulation of Binding of OPRK1 and OPRM1 1 0.38 0.3 1.03
17 INT135585 CSF2 Regulation of CCL2 1 0.13 2.51 0.95
18 INT81329 Binding of ARRB1 and OPRK1 1 0.05 0.1 0.93
19 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
20 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83
21 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
22 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
23 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
24 INT149495 PNOC Negative_regulation of CCL2 1 0.11 0.16 0.77
25 INT133941 ARFGEF1 Positive_regulation of OPRK1 1 0.02 0 0.76
26 INT133935 DNM2 Positive_regulation of OPRK1 1 0.11 0 0.76
27 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
28 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
29 INT126598 Binding of BSG and OPRK1 1 0.01 0.05 0.72
30 INT123869 Binding of GNAS and OPRK1 1 0.00 0.37 0.7
31 INT120017 CCL2 Positive_regulation of CCL3 1 0.01 0.99 0.7
32 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
33 INT120035 CCL2 Positive_regulation of Prap1 1 0.00 0.99 0.7
34 INT130717 Binding of OPRM1 and Positive_regulation of Localization of CCL2 1 0.00 0.72 0.68
35 INT116441 IL1B Positive_regulation of Gene_expression of CCL2 2 0.04 0.62 0.65
36 INT153750 Binding of CCL2 and Crp 1 0.02 1.8 0.65
37 INT153751 Regulation of Binding of CCL2 and Crp 1 0.03 1.8 0.65
38 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
39 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62
40 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62
41 INT176470 TNF Positive_regulation of Gene_expression of CCL2 1 0.15 0.62 0.58
42 INT147201 Binding of CCL2 and Hsp70-2os 1 0.00 0.76 0.57
43 INT86264 OPRK1 Negative_regulation of Gene_expression of HIVEP1 1 0.33 1.76 0.51
44 INT295708 Binding of EGF and CCL2 1 0.01 0.79 0.49
45 INT81331 ADRBK1 Regulation of OPRK1 1 0.03 0.09 0.48
46 INT112843 Binding of OPRK1 and Nfatc4 1 0.00 0 0.48
47 INT81330 ARRB1 Regulation of OPRK1 1 0.04 0.09 0.47
48 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
49 INT217040 Negative_regulation of IRF6 Positive_regulation of CCL2 1 0.00 1.24 0.47
50 INT217039 IRF6 Positive_regulation of CCL2 1 0.00 1.24 0.47
51 INT117703 OPRK1 Positive_regulation of Positive_regulation of JUN 1 0.01 0.08 0.47
52 INT81333 Binding of OPRK1 and SNORD50A 1 0.07 0.09 0.46
53 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
54 INT116934 OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
55 INT81335 Negative_regulation of Binding of OPRK1 and SNORD50A 1 0.08 0.1 0.46
56 INT116937 Positive_regulation of OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
57 INT116929 OPRK1 Positive_regulation of JUN 1 0.28 0.15 0.46
58 INT112800 CASP1 Positive_regulation of Gene_expression of CCL2 1 0.04 0.48 0.43
59 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
60 INT116931 OPRK1 Regulation of MAPK8 1 0.31 0.07 0.43
61 INT66196 OPRK1 Negative_regulation of Oprd1 1 0.00 0 0.43
62 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
63 INT163909 CCL2 Positive_regulation of Positive_regulation of Ccr2 1 0.05 0.19 0.36
64 INT70836 Positive_regulation of OPRK1 Positive_regulation of Binding of CRYGS 1 0.03 0.09 0.36
65 INT163906 CCL2 Positive_regulation of CCR2 1 0.18 0.2 0.35
66 INT353669 Binding of SNRNP70 and CD209 1 0.04 6.08 0.35
67 INT163908 CCL2 Positive_regulation of Ccr2 1 0.05 0.2 0.35
68 INT51629 Binding of DRD3 and OPRK1 1 0.15 0 0.33
69 INT134888 Negative_regulation of TNFRSF11A Negative_regulation of Gene_expression of CCL2 1 0.24 0.38 0.33
70 INT102953 OPRK1 Positive_regulation of Localization of ADRBK2 1 0.13 0 0.3
71 INT102955 OPRK1 Positive_regulation of Localization of ADRBK1 1 0.13 0 0.3
72 INT171257 TNFSF12 Positive_regulation of CCL2 1 0.01 0.3 0.29
73 INT306107 Binding of CCL2 and Ccr2 1 0.06 0 0.28
74 INT294709 IRF6 Positive_regulation of Gene_expression of CCL2 1 0.08 0.14 0.28
75 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27
76 INT306941 Tnfsf12 Positive_regulation of Gene_expression of CCL2 1 0.03 1.65 0.27
77 INT342458 CSF1 Positive_regulation of Gene_expression of CCL2 1 0.17 0.84 0.27
78 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
79 INT120896 Binding of CCL2 and Il6 1 0.08 1.2 0.26
80 INT252822 CCL2 Positive_regulation of Positive_regulation of FOS 1 0.04 0.75 0.25
81 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25
82 INT252786 CCL2 Regulation of Positive_regulation of FOS 1 0.05 0.75 0.25
83 INT252777 ROS1 Positive_regulation of Gene_expression of CCL2 1 0.31 0.77 0.23
84 INT112796 IL4I1 Positive_regulation of Gene_expression of CCL2 1 0.07 0 0.23
85 INT112801 IL4I1 Positive_regulation of CCL2 1 0.03 0 0.23
86 INT112798 CASP1 Positive_regulation of CCL2 1 0.02 0.19 0.21
87 INT252814 ELANE Positive_regulation of Positive_regulation of CCL2 1 0.05 0.8 0.2
88 INT306108 CCL2 Positive_regulation of Positive_regulation of Mapk3 1 0.03 0.15 0.2
89 INT252782 ROS1 Positive_regulation of Positive_regulation of CCL2 1 0.22 0.8 0.2
90 INT116440 LY9 Negative_regulation of Gene_expression of CCL2 1 0.14 0.09 0.16
91 INT303941 CCL2 Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
92 INT102954 Binding of ADRBK1 and OPRK1 1 0.11 0 0.14
93 INT206424 Binding of NFIA and ASAP1 1 0.33 0 0.13
94 INT220318 Binding of CPB1 and CCL2 1 0.01 0.46 0.13
95 INT180715 Binding of SARS and CLEC4M 2 0.12 2.92 0.11
96 INT62775 Regulation of Binding of NT5E and OPRK1 1 0.03 0 0.1
97 INT355590 VEGFA Positive_regulation of Gene_expression of CCL2 1 0.07 1.35 0.1
98 INT294453 KLK4 Negative_regulation of CCL2 1 0.00 0 0.1
99 INT62776 Binding of NT5E and OPRK1 1 0.02 0 0.1
100 INT213416 Binding of CCL2 and SET 1 0.11 0.17 0.1
101 INT355585 VEGFA Positive_regulation of Positive_regulation of CCL2 1 0.07 1.35 0.1
102 INT132804 Positive_regulation of IL4 Positive_regulation of CCL2 1 0.22 0.6 0.09
103 INT132794 Positive_regulation of IL13 Positive_regulation of CCL2 1 0.21 0.6 0.09
104 INT294711 CRP Regulation of CCL2 1 0.12 0 0.09
105 INT132815 Positive_regulation of TNF Positive_regulation of CCL2 1 0.21 0.6 0.09
106 INT132793 IL4 Positive_regulation of CCL2 1 0.22 0.73 0.08
107 INT132816 IL13 Positive_regulation of CCL2 1 0.21 0.73 0.08
108 INT116439 CD8B Negative_regulation of Gene_expression of CCL2 1 0.02 0 0.08
109 INT286899 Binding of IL6 and CCL2 1 0.03 0.92 0.08
110 INT132811 IL1B Positive_regulation of CCL2 1 0.15 0.6 0.08
111 INT154716 Binding of MON1B and CD209 1 0.01 1.76 0.08
112 INT353666 Gene_expression of CD209 Negative_regulation of GOPC 1 0.06 0.67 0.08
113 INT132814 TNF Positive_regulation of CCL2 1 0.21 0.6 0.08
114 INT288027 VEGFA Regulation of CCL2 1 0.44 0.26 0.03
115 INT132799 IL4 Positive_regulation of Localization of CCL2 1 0.22 0.13 0
116 INT164895 IL33 Positive_regulation of Gene_expression of CCL2 1 0.16 0.05 0
117 INT103680 Serpinf1 Negative_regulation of Positive_regulation of CCL2 1 0.00 0.15 0
118 INT206082 IL6 Positive_regulation of Gene_expression of CCL2 1 0.07 0.3 0
119 INT132790 IL13 Positive_regulation of Localization of CCL2 1 0.21 0.13 0
120 INT83446 CD40LG Positive_regulation of Localization of CCL2 1 0.00 0.17 0
121 INT355638 OLR1 Positive_regulation of Localization of CCL2 1 0.02 1.42 0
122 INT353661 Binding of CD209 and SENP8 1 0.07 1.39 0
123 INT132797 IL1B Positive_regulation of Localization of CCL2 1 0.48 0.12 0
124 INT353664 SNRNP70 Regulation of Gene_expression of CD209 1 0.05 1.62 0
125 INT132798 TNF Positive_regulation of Localization of CCL2 1 0.29 0.12 0
126 INT355642 OLR1 Positive_regulation of Gene_expression of CCL2 1 0.03 2.85 0
127 INT353668 Binding of ICAM3 and CD209 1 0.15 3.05 0
128 INT232514 RS1 Regulation of Gene_expression of CCL2 1 0.00 0.26 0
129 INT103678 Serpinf1 Negative_regulation of CCL2 1 0.00 0.28 0
130 INT103679 Serpinf1 Negative_regulation of Gene_expression of CCL2 1 0.00 0.15 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for viral genome replication. They are ordered first by their pain relevance and then by number of times they were reported in viral genome replication. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
2 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
3 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18
4 INT10304 Binding of OPRK1 89 0.48 9.28 49.42
5 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
6 INT29105 Positive_regulation of OPRK1 68 0.70 7.06 44.69
7 INT65698 Localization of CCL2 118 0.81 77.54 32.69
8 INT7845 Regulation of OPRK1 44 0.62 4.54 30.49
9 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
10 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
11 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
12 INT20881 Negative_regulation of OPRK1 20 0.43 3.73 13.37
13 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
14 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83
15 INT50191 Positive_regulation of Gene_expression of OPRK1 9 0.67 3.44 7.91
16 INT81493 Transcription of CCL2 20 0.65 13.63 6.78
17 INT12699 Transcription of OPRK1 11 0.52 0.08 6.66
18 INT120895 Binding of CCL2 22 0.37 15.86 6.55
19 INT76741 Localization of OPRK1 7 0.68 0.22 5.9
20 INT74182 Positive_regulation of Binding of OPRK1 8 0.49 1.39 5.25
21 INT29354 Regulation of Binding of OPRK1 7 0.60 1.72 5.04
22 INT96851 Negative_regulation of Localization of CCL2 14 0.53 5.98 4.57
23 INT102363 Negative_regulation of Positive_regulation of OPRK1 7 0.43 0.99 4.25
24 INT66782 Negative_regulation of Gene_expression of OPRK1 4 0.28 1.42 3.41
25 INT80521 Negative_regulation of Binding of OPRK1 4 0.43 0.8 2.93
26 INT52166 Positive_regulation of Positive_regulation of OPRK1 2 0.57 0.48 2.74
27 INT85597 Positive_regulation of Localization of OPRK1 2 0.45 0 2.65
28 INT113906 Regulation of Positive_regulation of CCL2 4 0.27 3.2 2.17
29 INT113907 Regulation of Localization of CCL2 5 0.62 2.46 2.05
30 INT100490 Negative_regulation of Positive_regulation of CCL2 6 0.23 1.48 1.96
31 INT67980 Positive_regulation of Positive_regulation of CCL2 7 0.49 5.89 1.85
32 INT204181 Gene_expression of CD209 22 0.64 30.66 1.47
33 INT81497 Positive_regulation of Transcription of CCL2 4 0.63 2 1.25
34 INT118924 Positive_regulation of Regulation of OPRK1 2 0.68 0 1
35 INT117552 Regulation of Regulation of CCL2 1 0.13 0.57 0.8
36 INT121687 Positive_regulation of Negative_regulation of OPRK1 1 0.49 0 0.79
37 INT120010 Negative_regulation of Transcription of CCL2 1 0.02 0.99 0.72
38 INT44118 Binding of CD209 10 0.35 8.83 0.69
39 INT222998 Positive_regulation of Negative_regulation of CCL2 1 0.12 1.11 0.59
40 INT118923 Protein_catabolism of OPRK1 1 0.00 0 0.59
41 INT71672 Phosphorylation of OPRK1 2 0.12 0 0.56
42 INT102776 Phosphorylation of CCL2 1 0.65 1.55 0.56
43 INT70840 Regulation of Positive_regulation of OPRK1 1 0.09 0.09 0.5
44 INT290397 Positive_regulation of Binding of CCL2 1 0.22 0.99 0.46
45 INT146074 Regulation of Transcription of OPRK1 1 0.26 0 0.34
46 INT222804 Positive_regulation of Gene_expression of CD209 6 0.48 6.44 0.28
47 INT245196 Negative_regulation of CD209 5 0.11 4.83 0.21
48 INT222810 Positive_regulation of CD209 4 0.48 3.14 0.16
49 INT181237 Negative_regulation of Negative_regulation of OPRK1 1 0.07 0 0.14
50 INT306938 Regulation of Transcription of CCL2 1 0.05 0.81 0.13
51 INT239550 Negative_regulation of Binding of CCL2 1 0.18 0 0.13
52 INT206457 Binding of NFIA 1 0.47 0 0.12
53 INT353675 Transcription of CD209 1 0.50 1.5 0.04
54 INT353676 Regulation of Gene_expression of CD209 1 0.22 0.43 0.03
55 INT204182 Localization of CD209 2 0.13 0.89 0
56 INT222793 Binding of CLEC4M 1 0.05 0.56 0
57 INT353677 Regulation of CD209 1 0.26 0.82 0
58 INT222809 Positive_regulation of Gene_expression of CLEC4M 1 0.05 0.67 0
59 INT152022 Regulation of Negative_regulation of CCL2 1 0.14 0 0
60 INT353680 Positive_regulation of Transcription of CD209 1 0.44 1.09 0
61 INT222807 Gene_expression of CLEC4M 1 0.06 0.67 0
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