GO:0019221

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Name cytokine-mediated signaling pathway
Categary Process
Go Slim No
Go Link GO:0019221
Unique Molecular Interactions 4213
Total Molecular Interactions 6213
Total Single Events 43688
Pain Genes Associated 235

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cytokine-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for cytokine-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
5 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
6 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
7 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81
8 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
9 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
10 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
11 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4
12 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
13 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
14 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
15 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
16 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
17 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
18 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
19 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
20 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
21 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
22 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
23 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
24 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
25 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
26 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
27 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
28 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
29 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
30 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
31 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
32 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
33 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
34 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
35 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
36 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2
37 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
38 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
39 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
40 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
41 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
42 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
43 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
44 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13
45 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
46 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
47 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
48 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01
49 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
50 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
51 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
52 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
53 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
54 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
55 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
56 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
57 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
58 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
59 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
60 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
61 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
62 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
63 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
64 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
65 INT157459 Binding of CX3CR1 and CX3CL1 1 0.32 2.12 1.7
66 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
67 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
68 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
69 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
70 INT172047 Binding of HLA-A and LRRC23 1 0.22 3.32 1.64
71 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
72 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
73 INT174503 Binding of HLA-B and KIR3DL1 6 0.37 3.48 1.61
74 INT107965 Binding of HLA-B and Mefv 2 0.34 3.91 1.61
75 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
76 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
77 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
78 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
79 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
80 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
81 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
82 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
83 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
84 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
85 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
86 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
87 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
88 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5
89 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
90 INT174450 Positive_regulation of Binding of Cxcr3 and Smcp 1 0.18 2.83 1.49
91 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49
92 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
93 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
94 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
95 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
96 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
97 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
98 INT318491 IRF6 Positive_regulation of FPR2 1 0.10 6.14 1.44
99 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
100 INT238005 Binding of Cxcr3 and Cxcl10 2 0.38 3.73 1.42
101 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
102 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
103 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4
104 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
105 INT55837 Binding of HLA-B and PHB2 3 0.20 3.52 1.37
106 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37
107 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
108 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
109 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
110 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
111 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
112 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
113 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34
114 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33
115 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
116 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
117 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
118 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
119 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
120 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
121 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
122 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
123 INT136200 Binding of Penk and NUP37 1 0.04 0 1.28
124 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
125 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
126 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
127 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
128 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27
129 INT8409 IL1A Positive_regulation of Positive_regulation of Vip 1 0.01 0.63 1.27
130 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26
131 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
132 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
133 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
134 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
135 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
136 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
137 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
138 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
139 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23
140 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
141 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
142 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
143 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
144 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
145 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
146 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
147 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
148 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
149 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
150 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
151 INT184402 Binding of HLA-DRB4 and HLA-E 1 0.00 3.1 1.19
152 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
153 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
154 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
155 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
156 INT340439 Binding of HLA-DMA and SUGT1 1 0.00 4.1 1.16
157 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
158 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
159 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
160 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
161 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
162 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
163 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
164 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
165 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14
166 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
167 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
168 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
169 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
170 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
171 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
172 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
173 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
174 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11
175 INT237999 Binding of Cxcr3 and Cxcl11 2 0.45 3.49 1.11
176 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
177 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
178 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11
179 INT107269 Binding of HLA-A and NCR3 1 0.35 1.42 1.1
180 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
181 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
182 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
183 INT107265 Binding of HLA-DRB1 and ITGAL 1 0.01 1.41 1.1
184 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1
185 INT107263 Binding of HLA-DRB1 and NCR3 1 0.40 1.42 1.1
186 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
187 INT333966 Binding of Il6r and Il6st 1 0.01 1.74 1.1
188 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
189 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
190 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
191 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
192 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
193 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
194 INT164378 MAPK3 Positive_regulation of Transcription of PDYN 1 0.50 0.2 1.09
195 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
196 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
197 INT142661 Binding of IFIT1 and NPY2R 1 0.00 2.49 1.08
198 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
199 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
200 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for cytokine-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in cytokine-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
3 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
4 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
5 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
6 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
7 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
8 INT1878 Binding of HLA-B 440 0.48 321.16 127.36
9 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
10 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
11 INT12082 Localization of IL6 365 0.81 241.78 105.78
12 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
13 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
14 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
15 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
16 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37
17 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
18 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
19 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
20 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
21 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
22 INT6849 Localization of IL1B 229 0.81 112.56 69.63
23 INT19511 Localization of Il6 212 0.81 118.17 67.67
24 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
25 INT11937 Localization of Il6 228 0.81 139.83 64.39
26 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
27 INT10706 Regulation of Il6 150 0.62 93.23 62.34
28 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
29 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
30 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
31 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
32 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
33 INT9210 Regulation of IL6 166 0.62 125.61 49.95
34 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
35 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01
36 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
37 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
38 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
39 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
40 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
41 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
42 INT11854 Gene_expression of Il1rl1 57 0.77 30.19 38.25
43 INT168410 Gene_expression of Cxcr3 81 0.75 84.03 37.01
44 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
45 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28
46 INT6484 Binding of IL1B 122 0.47 75.84 35.07
47 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78
48 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72
49 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66
50 INT65698 Localization of CCL2 118 0.81 77.54 32.69
51 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
52 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
53 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4
54 INT9655 Regulation of Il6 98 0.62 70.92 31.95
55 INT9347 Localization of Il1b 58 0.81 26.13 31.53
56 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
57 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
58 INT86437 Binding of IL6 154 0.48 121.22 29.3
59 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58
60 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
61 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07
62 INT82882 Localization of Ccl2 61 0.80 41.96 28
63 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81
64 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51
65 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81
66 INT5966 Localization of Il1a 50 0.78 22.91 26.54
67 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
68 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2
69 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
70 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
71 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14
72 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03
73 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
74 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
75 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54
76 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09
77 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
78 INT19330 Binding of HLA-A 99 0.48 76.26 22.85
79 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67
80 INT12114 Positive_regulation of Tnfrsf1a 46 0.69 36.26 22.54
81 INT48081 Localization of Il1b 46 0.80 21.59 22.4
82 INT1876 Positive_regulation of HLA-B 82 0.69 52.16 21.08
83 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96
84 INT97798 Localization of IRF6 86 0.73 33.27 20.94
85 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61
86 INT51474 Binding of Il6 55 0.48 44.99 20.52
87 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
88 INT49985 Transcription of Il6 62 0.72 40.13 20.29
89 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81
90 INT157463 Gene_expression of CX3CL1 55 0.62 69.05 19.75
91 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
92 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19
93 INT5160 Localization of PTAFR 61 0.80 42.6 19.16
94 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
95 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
96 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
97 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
98 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
99 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24
100 INT167679 Gene_expression of Ccr5 74 0.75 59.03 18.16
101 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
102 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
103 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88
104 INT61626 Transcription of IL6 73 0.72 42.04 17.86
105 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85
106 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72
107 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
108 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
109 INT10187 Gene_expression of Il2ra 91 0.78 52.67 16.66
110 INT52358 Gene_expression of Cx3cr1 25 0.78 18.48 16.65
111 INT151434 Positive_regulation of Ccr2 26 0.68 18.34 16.34
112 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
113 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95
114 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
115 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
116 INT49376 Negative_regulation of Localization of Il6 37 0.59 12.66 14.99
117 INT129584 Positive_regulation of Stat3 97 0.68 87.07 14.86
118 INT93482 Localization of Rela 56 0.78 24.52 14.82
119 INT107585 Gene_expression of CCR2 35 0.71 26.44 14.75
120 INT121162 Gene_expression of Cx3cl1 22 0.78 11.56 14.59
121 INT11855 Positive_regulation of Gene_expression of Il1rl1 19 0.69 12.22 14.57
122 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
123 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18
124 INT22046 Negative_regulation of IRF6 52 0.43 25.69 14.13
125 INT11696 Gene_expression of HLA-A 50 0.78 41.25 14.1
126 INT11069 Positive_regulation of Pf4 35 0.68 27.7 13.96
127 INT83950 Gene_expression of Cxcr1 31 0.59 27.76 13.91
128 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68
129 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
130 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
131 INT4931 Localization of IFNG 53 0.78 33.25 13.65
132 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
133 INT11699 Binding of HLA-E 85 0.47 52.51 13.41
134 INT99586 Binding of IRF6 60 0.36 27.87 13.2
135 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
136 INT63361 Gene_expression of CD44 126 0.77 71.58 12.96
137 INT54763 Binding of Il6 82 0.48 63.27 12.89
138 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
139 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
140 INT89294 Gene_expression of Ccr3 53 0.68 43.9 12.62
141 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
142 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
143 INT60461 Positive_regulation of Gene_expression of Il1a 40 0.61 17.23 12.35
144 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
145 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
146 INT16322 Gene_expression of Il2rb 19 0.51 15.88 12.18
147 INT73829 Positive_regulation of Gene_expression of VCAM1 41 0.61 35.96 11.92
148 INT65638 Negative_regulation of Gene_expression of Il1rl1 12 0.58 7.86 11.7
149 INT50933 Transcription of Il6 38 0.72 24.31 11.58
150 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58
151 INT13303 Positive_regulation of PTAFR 40 0.69 16.27 11.56
152 INT65713 Localization of ICAM1 42 0.81 39.55 11.49
153 INT176607 Gene_expression of Cx3cl1 27 0.75 19.51 11.32
154 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
155 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96
156 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
157 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89
158 INT14962 Gene_expression of Pf4 27 0.76 22.48 10.88
159 INT121161 Localization of Cx3cl1 14 0.75 10.07 10.61
160 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59
161 INT15804 Gene_expression of ISG20 83 0.75 44.33 10.58
162 INT23177 Negative_regulation of Gene_expression of HLA-DRA 50 0.44 16.99 10.55
163 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53
164 INT87393 Gene_expression of Ccr5 19 0.65 11 10.51
165 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
166 INT99784 Positive_regulation of Cxcr3 22 0.66 22.44 10.36
167 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34
168 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98
169 INT49660 Positive_regulation of EGR1 54 0.69 32.17 9.89
170 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83
171 INT181344 Gene_expression of Ccr6 28 0.61 24.34 9.78
172 INT106200 Binding of Ccl2 22 0.42 16.7 9.75
173 INT80549 Binding of ICAM1 53 0.47 42.76 9.72
174 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
175 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5
176 INT114874 Gene_expression of Stat3 78 0.76 53.99 9.49
177 INT97439 Positive_regulation of Il5 46 0.60 25.6 9.47
178 INT3925 Negative_regulation of HLA-B 29 0.42 20.19 9.46
179 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45
180 INT140224 Localization of Ccl2 32 0.72 26.91 9.39
181 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
182 INT73021 Gene_expression of EGR1 43 0.77 24.65 9.18
183 INT62829 Positive_regulation of VCAM1 39 0.70 38.42 9.15
184 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08
185 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06
186 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95
187 INT161222 Positive_regulation of Ccr2 13 0.55 13.77 8.89
188 INT141502 Positive_regulation of CX3CL1 21 0.55 25.8 8.88
189 INT157467 Positive_regulation of Gene_expression of CX3CL1 6 0.55 16.67 8.84
190 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83
191 INT15768 Gene_expression of Il1a 20 0.71 9.31 8.78
192 INT66213 Localization of RELA 63 0.78 14.71 8.77
193 INT8903 Gene_expression of IFNA2 58 0.71 38.23 8.68
194 INT88047 Positive_regulation of Gene_expression of Ccr2 15 0.60 10.5 8.63
195 INT3353 Localization of HLA-B 25 0.75 16.05 8.62
196 INT123382 Gene_expression of Cxcr2 12 0.69 4.62 8.62
197 INT77790 Positive_regulation of Gene_expression of Tnfrsf1a 16 0.67 15.88 8.5
198 INT12861 Gene_expression of Cish 40 0.57 23.01 8.48
199 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42
200 INT28671 Positive_regulation of Gene_expression of HLA-E 43 0.67 22.85 8.39
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