GO:0019222

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Name regulation of metabolic process
Categary Process
Go Slim No
Go Link GO:0019222
Unique Molecular Interactions 595
Total Molecular Interactions 892
Total Single Events 7020
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for regulation of metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
2 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
3 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
4 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
5 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
6 INT152699 Bdnf Positive_regulation of Ltp 5 0.05 1.22 2.95
7 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
8 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
9 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
10 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
11 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
12 INT340117 Binding of Bdnf and Pain1 1 0.01 2.48 2.55
13 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37
14 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
15 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
16 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
17 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
18 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79
19 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
20 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
21 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
22 INT127253 Binding of Npb and Npbwr1 2 0.29 0.61 1.55
23 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
24 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
25 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
26 INT131564 Binding of Npw and Npbwr1 3 0.41 0.35 1.46
27 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
28 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
29 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
30 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
31 INT326194 Bdnf Regulation of Slc12a5 1 0.05 0.85 1.35
32 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34
33 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
34 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
35 INT96708 Bdnf Positive_regulation of Localization of SST 1 0.01 0 1.3
36 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
37 INT159655 Binding of BDNF and INSRR 2 0.00 1.25 1.26
38 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
39 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
40 INT50386 Bdnf Regulation of Npy 1 0.21 0.47 1.24
41 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23
42 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2
43 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17
44 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
45 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
46 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11
47 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
48 INT81788 Binding of AGRP and MC4R 4 0.51 0 1.09
49 INT87320 Ngf Regulation of Gene_expression of Bdnf 2 0.38 0.97 1.06
50 INT331108 Mc1r Positive_regulation of Mc4r 1 0.44 1.05 1.06
51 INT134534 Binding of Bdnf and Psds1 1 0.01 0 1.05
52 INT160541 Binding of BDNF and PSIP1 4 0.49 1.94 1.02
53 INT224856 Binding of Bdnf and Eef2 1 0.14 0 1.02
54 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01
55 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
56 INT105668 Binding of AAVS1 and BDNF 1 0.08 0.94 0.95
57 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95
58 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93
59 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
60 INT180772 Bdnf Regulation of Trpv1 1 0.11 0.29 0.9
61 INT180777 Bdnf Regulation of Gene_expression of Trpv1 1 0.18 0.29 0.9
62 INT152700 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
63 INT152701 Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
64 INT326663 Bdnf Regulation of Positive_regulation of Arc 1 0.16 1.46 0.88
65 INT152694 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
66 INT48463 Bdnf Positive_regulation of Gene_expression of Sst 1 0.25 0 0.88
67 INT152695 Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
68 INT261783 Bdnf Regulation of Gene_expression of Slc12a5 1 0.09 0 0.87
69 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87
70 INT337899 Positive_regulation of MC3R Positive_regulation of Gene_expression of Bdnf 1 0.31 0 0.87
71 INT215596 Bdnf Positive_regulation of Negative_regulation of Slc12a5 1 0.14 0.76 0.86
72 INT326664 Bdnf Positive_regulation of Arc 1 0.27 1.07 0.86
73 INT326661 Bdnf Positive_regulation of Gene_expression of Arc 1 0.27 1.96 0.86
74 INT261786 Bdnf Negative_regulation of Slc12a5 1 0.14 0.05 0.85
75 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84
76 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83
77 INT340113 Comt Regulation of Bdnf 1 0.21 0.74 0.82
78 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
79 INT128042 Bdnf Positive_regulation of Phosphorylation of Ephb1 1 0.22 0.2 0.8
80 INT180782 Bdnf Positive_regulation of Calca 1 0.16 0.77 0.8
81 INT245564 Runx3 Negative_regulation of Ntrk2 3 0.61 1.61 0.79
82 INT128041 Bdnf Positive_regulation of Trib3 1 0.10 0.29 0.79
83 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
84 INT224281 Bdnf Regulation of Gene_expression of Gap43 1 0.36 0.4 0.77
85 INT224283 Bdnf Regulation of Gene_expression of Calca 1 0.19 0.35 0.76
86 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
87 INT127254 Binding of Gpr176 and Npbwr1 1 0.02 0.49 0.72
88 INT180765 Calca Regulation of Binding of Bdnf 1 0.15 0.15 0.72
89 INT351375 Mir470 Negative_regulation of Ntrk2 1 0.01 1.54 0.7
90 INT219035 Nkx1-1 Regulation of Gene_expression of Bdnf 1 0.13 0.88 0.7
91 INT165583 Binding of Bdnf and Ngf 3 0.33 0.81 0.69
92 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
93 INT287099 Binding of Bdnf and T 1 0.10 1.1 0.69
94 INT250932 IL1B Regulation of Gene_expression of BDNF 1 0.06 0.24 0.69
95 INT224892 Bdnf Regulation of Localization of Ltp 1 0.03 0.17 0.69
96 INT224893 Bdnf Regulation of Ltp 1 0.03 0.17 0.69
97 INT161186 Bdnf Regulation of Gene_expression of Ntrk2 1 0.44 1.05 0.68
98 INT142244 Positive_regulation of Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67
99 INT180805 Bdnf Regulation of Sorbs1 1 0.01 0.14 0.67
100 INT161183 NMS Positive_regulation of Gene_expression of Bdnf 1 0.40 1.3 0.67
101 INT142243 Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67
102 INT161184 NMS Positive_regulation of Gene_expression of Ntrk2 1 0.55 1.3 0.67
103 INT82306 Bdnf Positive_regulation of Gene_expression of Fos 1 0.68 0.64 0.65
104 INT242635 Binding of Bdnf and Ntrk3 3 0.25 0.98 0.64
105 INT326193 Bdnf Positive_regulation of Car2 2 0.14 0.11 0.62
106 INT93690 Bdnf Regulation of Localization of Tacr1 1 0.10 0.28 0.61
107 INT257717 Binding of Bdnf and Vgf 1 0.25 0.86 0.61
108 INT271194 Binding of Bdnf and Gopc 1 0.03 0.49 0.6
109 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
110 INT287096 Binding of Bdnf and FL 1 0.16 1.15 0.6
111 INT90119 Ntrk2 Regulation of Gene_expression of Nfkb1 1 0.01 0.27 0.6
112 INT79740 Ntf3 Regulation of Positive_regulation of Ntrk2 1 0.28 0 0.6
113 INT164455 Ngf Negative_regulation of Bdnf 1 0.05 0.59 0.59
114 INT90115 Ntrk2 Regulation of Jun 1 0.01 0.27 0.57
115 INT257715 Bdnf Positive_regulation of Transcription of Vgf 1 0.35 0.66 0.57
116 INT290594 BDNF Positive_regulation of Localization of S100B 1 0.08 0.6 0.57
117 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
118 INT298271 Proc Negative_regulation of Gene_expression of Ntrk2 1 0.01 0.79 0.56
119 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56
120 INT298278 Runx1 Negative_regulation of Gene_expression of Ntrk2 1 0.44 0.8 0.56
121 INT145718 Positive_regulation of Plat Positive_regulation of Bdnf 1 0.20 0 0.56
122 INT147273 Bdnf Regulation of Syp 1 0.24 0 0.56
123 INT261481 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.02 0.21 0.56
124 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
125 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55
126 INT108021 Binding of Pomc and Mc4r 1 0.00 0.97 0.55
127 INT147274 Bdnf Regulation of Gap43 1 0.37 0 0.55
128 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53
129 INT214164 Binding of Mc4r and Pomc 1 0.39 1.31 0.53
130 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53
131 INT143854 Ngf Regulation of Transcription of Bdnf 1 0.09 0.61 0.53
132 INT240192 RBX1 Negative_regulation of BDNF 1 0.08 0.13 0.52
133 INT143862 Bdnf Positive_regulation of Gene_expression of NUP214 1 0.27 0.61 0.52
134 INT143859 Bdnf Positive_regulation of Gene_expression of Nfatc1 1 0.00 0.61 0.52
135 INT193554 Ntrk2 Positive_regulation of Positive_regulation of Ephb1 1 0.01 0.73 0.52
136 INT89186 Agrp Negative_regulation of Mc4r 1 0.40 0 0.51
137 INT163481 Binding of Bdnf and Positive_regulation of Regulation of Helt 1 0.21 0 0.51
138 INT163480 Bdnf Positive_regulation of Regulation of Helt 1 0.22 0 0.51
139 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
140 INT134533 Binding of Ntrk2 and Psds1 1 0.01 0 0.5
141 INT250933 IL1B Positive_regulation of Gene_expression of BDNF 1 0.10 0.27 0.5
142 INT130335 Binding of Mc4r and Nr3c2 1 0.06 1.87 0.5
143 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5
144 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5
145 INT242638 Binding of BDNF and Gdnf 1 0.29 0 0.49
146 INT114543 Bdnf Positive_regulation of Prkcg 1 0.21 0 0.49
147 INT257720 Bdnf Regulation of Vgf 1 0.19 0.64 0.49
148 INT219038 Creb1 Regulation of Gene_expression of Bdnf 1 0.25 0.25 0.49
149 INT304578 Negative_regulation of HDAC9 Positive_regulation of Gene_expression of Bdnf 1 0.06 0.9 0.49
150 INT320451 ECT Positive_regulation of Gene_expression of BDNF 1 0.05 1.21 0.49
151 INT165582 Binding of Bdnf and Gdnf 1 0.36 0.47 0.49
152 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48
153 INT273110 Bdnf Regulation of Positive_regulation of Gria1 1 0.43 0 0.47
154 INT305735 Binding of Bdnf and Creb1 1 0.08 0.49 0.47
155 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47
156 INT309127 Edc4 Positive_regulation of Bdnf 1 0.04 0.37 0.47
157 INT305746 Positive_regulation of Creb1 Positive_regulation of BDNF 1 0.32 0.41 0.47
158 INT305743 Binding of Bdnf and Positive_regulation of Positive_regulation of Creb1 1 0.11 0.49 0.47
159 INT235882 Creb1 Positive_regulation of Positive_regulation of Bdnf 1 0.11 0.17 0.47
160 INT305736 Positive_regulation of Creb1 Positive_regulation of Bdnf 1 0.10 0.41 0.46
161 INT96710 Ntf3 Regulation of BDNF 1 0.02 0 0.45
162 INT128043 Positive_regulation of Ntrk2 Positive_regulation of Phosphorylation of Trib3 1 0.07 0.34 0.45
163 INT224282 Binding of Bdnf and Il6 1 0.08 0.26 0.45
164 INT190870 BDNF Positive_regulation of Phosphorylation of Mapk1 1 0.12 0.54 0.44
165 INT305745 Binding of Bdnf and Positive_regulation of BDNF 1 0.17 0.44 0.44
166 INT261782 Bdnf Positive_regulation of Gene_expression of Slc12a5 1 0.18 0 0.44
167 INT180781 Bdnf Positive_regulation of Zbtb38 1 0.00 0.93 0.44
168 INT172239 Binding of NPBWR1 and NPBWR2 1 0.17 0.27 0.44
169 INT154592 Binding of Ntrk2 and Positive_regulation of Gene_expression of Kcna3 1 0.11 0.16 0.44
170 INT132863 Positive_regulation of Ngf Positive_regulation of Bdnf 1 0.23 1.11 0.43
171 INT127075 Bdnf Regulation of Gene_expression of Jun 1 0.11 0.28 0.43
172 INT240193 RBX1 Positive_regulation of Gene_expression of BDNF 1 0.10 0 0.43
173 INT127073 Bdnf Regulation of Gene_expression of Fos 1 0.42 0.28 0.43
174 INT55829 Bdnf Positive_regulation of Gene_expression of Qrfp 1 0.09 0 0.42
175 INT237471 Ltp Regulation of Bdnf 1 0.02 0.13 0.42
176 INT309157 Aqp1 Positive_regulation of Bdnf 1 0.00 0.74 0.42
177 INT127078 Bdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
178 INT127076 Gene_expression of Bdnf Positive_regulation of Gene_expression of IER3 1 0.03 0.26 0.42
179 INT273111 Bdnf Positive_regulation of Positive_regulation of Mtor 1 0.44 0.07 0.42
180 INT224894 Bdnf Positive_regulation of Positive_regulation of IER3 1 0.00 0.36 0.41
181 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
182 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
183 INT148438 Binding of Bdnf and Ntf3 1 0.33 1.14 0.4
184 INT118919 Binding of FRTS and Sh2b2 1 0.24 0 0.39
185 INT309115 Edc4 Positive_regulation of Gene_expression of Bdnf 1 0.04 0.77 0.39
186 INT298296 Gene_expression of Runx1 Negative_regulation of Gene_expression of Ntrk2 1 0.44 0.33 0.39
187 INT91719 Binding of BDNF and LIF 1 0.09 1.65 0.38
188 INT261788 Bdnf Regulation of Slc12a5 1 0.10 0.07 0.38
189 INT201485 Ntrk2 Positive_regulation of Prkcg 1 0.01 0.73 0.38
190 INT283746 Tbs1 Positive_regulation of Regulation of Bdnf 1 0.01 0 0.38
191 INT91720 Binding of BDNF and CNTF 1 0.09 1.71 0.38
192 INT283742 Tbs1 Positive_regulation of Transcription of Bdnf 1 0.01 0 0.38
193 INT214142 Agrp Positive_regulation of Mc4r 1 0.39 0.23 0.37
194 INT214145 Binding of Agrp and Mc4r 1 0.40 0.18 0.37
195 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
196 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
197 INT283744 Bdnf Positive_regulation of Tbs1 1 0.01 0 0.36
198 INT224284 BDNF Positive_regulation of Ephb1 1 0.36 0.22 0.36
199 INT340607 Bdnf Regulation of Gene_expression of Creb1 1 0.36 0.31 0.36
200 INT224285 BDNF Positive_regulation of Trib3 1 0.06 0.22 0.36

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in regulation of metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1
2 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82
3 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68
4 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01
5 INT67682 Localization of Bdnf 204 0.81 72.36 88.92
6 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12
7 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5
8 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24
9 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81
10 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55
11 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
12 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64
13 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
14 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77
15 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78
16 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5
17 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99
18 INT47685 Positive_regulation of Positive_regulation of Bdnf 32 0.70 20.05 27.03
19 INT56053 Negative_regulation of Bdnf 77 0.58 64.4 26.83
20 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
21 INT96557 Binding of Bdnf 46 0.47 21.74 24.26
22 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
23 INT113925 Localization of Bdnf 59 0.79 24.03 22.76
24 INT102203 Transcription of Bdnf 35 0.71 18.26 20.59
25 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59
26 INT64442 Regulation of Mc4r 6 0.62 5.22 19.09
27 INT103469 Positive_regulation of Gene_expression of BDNF 59 0.67 24.39 18.36
28 INT106556 Negative_regulation of Gene_expression of Bdnf 42 0.59 34.71 17.64
29 INT102903 Regulation of Gene_expression of Bdnf 35 0.62 20.1 17.42
30 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23
31 INT96299 Positive_regulation of Localization of Bdnf 35 0.70 15.67 16.09
32 INT64447 Transcription of Mc4r 14 0.61 6.08 15.29
33 INT163479 Binding of Bdnf 36 0.48 25.77 14.83
34 INT100655 Regulation of BDNF 51 0.60 21.49 13.14
35 INT47692 Negative_regulation of Positive_regulation of Bdnf 18 0.59 9.64 13.14
36 INT65172 Negative_regulation of Ntrk2 35 0.59 9.89 13.08
37 INT64445 Gene_expression of Mc4r 17 0.78 5.06 12.91
38 INT73641 Regulation of Lep 45 0.62 26.2 12.59
39 INT56048 Positive_regulation of Transcription of Bdnf 24 0.70 8.33 11.83
40 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
41 INT85017 Positive_regulation of Mc4r 13 0.67 7.56 10.86
42 INT72579 Localization of BDNF 56 0.80 14.84 10.65
43 INT89184 Gene_expression of Mc4r 55 0.77 23.85 10.65
44 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
45 INT103474 Regulation of Gene_expression of BDNF 40 0.60 12.14 9.65
46 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
47 INT136012 Regulation of Transcription of Bdnf 6 0.45 2.76 9.2
48 INT108931 Negative_regulation of BDNF 38 0.59 19.61 8.84
49 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75
50 INT47682 Transcription of Ntrk2 19 0.69 6.32 8.6
51 INT82082 Localization of Lep 63 0.81 26.41 8.56
52 INT75998 Transcription of BDNF 61 0.69 11.03 8.27
53 INT64449 Negative_regulation of Gene_expression of Mc4r 7 0.58 2 7.86
54 INT102207 Positive_regulation of Transcription of Bdnf 13 0.69 5.49 7.18
55 INT132860 Binding of BDNF 33 0.47 14.7 6.99
56 INT47691 Positive_regulation of Gene_expression of Ntrk2 17 0.62 13.64 6.96
57 INT64444 Negative_regulation of Mc4r 9 0.58 5.12 6.44
58 INT49883 Gene_expression of NPBWR1 9 0.77 3.66 6.32
59 INT47681 Regulation of Ntrk2 17 0.62 3.61 6.31
60 INT103477 Negative_regulation of Gene_expression of BDNF 23 0.52 10.63 6.26
61 INT91065 Regulation of Transcription of Bdnf 13 0.62 12.48 6.13
62 INT43524 Positive_regulation of Sh2b2 16 0.58 2.95 5.78
63 INT56047 Negative_regulation of Transcription of Bdnf 16 0.59 8.02 5.67
64 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
65 INT106552 Positive_regulation of Gene_expression of Ntrk2 19 0.68 9.72 5.51
66 INT91338 Binding of Lep 31 0.48 26.86 5.39
67 INT107103 Negative_regulation of Ntrk2 21 0.59 10.38 5.28
68 INT102935 Regulation of Lep 31 0.60 18.47 5.24
69 INT110666 Phosphorylation of Bdnf 12 0.69 5.67 5.21
70 INT67681 Negative_regulation of Localization of Bdnf 12 0.50 4.37 5.07
71 INT106555 Binding of Ntrk2 15 0.48 6.31 5.05
72 INT105609 Negative_regulation of Mc4r 10 0.58 10.4 5.04
73 INT64446 Negative_regulation of Transcription of Mc4r 4 0.43 1.01 4.8
74 INT64441 Regulation of Transcription of Mc4r 3 0.27 2.93 4.62
75 INT97391 Binding of Lep 18 0.48 8.97 4.47
76 INT65056 Binding of Ntrk2 20 0.36 3.72 4.42
77 INT122882 Regulation of Ntrk2 13 0.62 9.7 4.3
78 INT113926 Positive_regulation of Localization of Bdnf 7 0.56 3.15 4.25
79 INT47686 Regulation of Gene_expression of Ntrk2 5 0.44 5.24 4.14
80 INT163581 Localization of Lep 27 0.79 18.99 4.08
81 INT106553 Positive_regulation of Positive_regulation of Bdnf 11 0.43 5.35 4.07
82 INT200047 Negative_regulation of Gene_expression of Ntrk2 8 0.56 10.78 3.95
83 INT92509 Regulation of Sh2b2 7 0.35 3.41 3.8
84 INT152743 Positive_regulation of Localization of BDNF 7 0.56 4.04 3.74
85 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
86 INT134527 Phosphorylation of Ntrk2 7 0.69 3.72 3.65
87 INT82305 Regulation of Localization of Bdnf 10 0.40 3 3.62
88 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
89 INT82850 Transcription of Npbwr1 8 0.72 0.94 3.29
90 INT48292 Negative_regulation of Sh2b2 9 0.26 2.14 3.26
91 INT48462 Positive_regulation of Negative_regulation of Bdnf 8 0.70 1 3.2
92 INT183212 Positive_regulation of Regulation of Bdnf 4 0.45 1.57 3.14
93 INT66599 Gene_expression of MC4R 16 0.78 12.37 3.12
94 INT210838 Positive_regulation of Mc4r 17 0.53 6.79 3.06
95 INT126567 Positive_regulation of Positive_regulation of BDNF 8 0.59 6.16 3.06
96 INT280461 Negative_regulation of Localization of Bdnf 3 0.37 2.63 2.9
97 INT82851 Gene_expression of Npbwr1 9 0.78 0.88 2.83
98 INT142237 Phosphorylation of Ntrk2 8 0.82 2.24 2.82
99 INT170557 Gene_expression of Lepr 16 0.67 17.26 2.78
100 INT280459 Regulation of Gene_expression of Ntrk2 13 0.62 8.48 2.71
101 INT130028 Positive_regulation of Gene_expression of Mc4r 2 0.45 0.41 2.7
102 INT119516 Positive_regulation of Phosphorylation of Bdnf 3 0.21 2.81 2.68
103 INT182893 Gene_expression of Sh2b2 8 0.65 1.74 2.65
104 INT201646 Negative_regulation of Transcription of Bdnf 8 0.58 7.14 2.59
105 INT67621 Negative_regulation of Gene_expression of Ntrk2 7 0.41 2.71 2.52
106 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
107 INT210833 Regulation of Mc4r 4 0.30 1.57 2.38
108 INT123851 Positive_regulation of Gene_expression of NPBWR1 1 0.69 1.52 2.25
109 INT47687 Positive_regulation of Transcription of Ntrk2 5 0.45 2.42 2.24
110 INT107102 Negative_regulation of Positive_regulation of Ntrk2 6 0.54 1.61 2.21
111 INT168945 Positive_regulation of Binding of Bdnf 4 0.50 1.7 2.14
112 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
113 INT83392 Transcription of Lep 6 0.54 5.07 2.04
114 INT102205 Negative_regulation of Positive_regulation of Bdnf 6 0.50 3.77 1.91
115 INT96703 Negative_regulation of Localization of BDNF 4 0.41 0.42 1.86
116 INT92622 Regulation of Positive_regulation of Bdnf 4 0.39 2.16 1.81
117 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
118 INT101875 Binding of MC4R 6 0.47 0.19 1.73
119 INT113897 Positive_regulation of Transcription of Mc4r 1 0.45 0 1.7
120 INT102204 Positive_regulation of Regulation of Bdnf 3 0.43 1.74 1.67
121 INT240201 Regulation of Transcription of BDNF 5 0.45 1.09 1.66
122 INT103471 Positive_regulation of Transcription of BDNF 4 0.44 4.25 1.63
123 INT178264 Positive_regulation of Gene_expression of Mc4r 10 0.43 3.52 1.57
124 INT49882 Positive_regulation of NPBWR1 5 0.67 0.89 1.56
125 INT93350 Binding of Lepr 17 0.05 27.21 1.5
126 INT326192 Negative_regulation of Binding of Ntrk2 1 0.10 1 1.47
127 INT207005 Regulation of Localization of Bdnf 6 0.45 3.85 1.45
128 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44
129 INT142241 Positive_regulation of Positive_regulation of Ntrk2 3 0.66 0.87 1.43
130 INT155699 Phosphorylation of Bdnf 5 0.81 1.49 1.37
131 INT240207 Regulation of Positive_regulation of BDNF 1 0.45 0.32 1.36
132 INT112314 Regulation of Binding of Bdnf 3 0.38 0.61 1.34
133 INT127252 Binding of Npbwr1 3 0.31 0.76 1.34
134 INT245544 Localization of Ntrk2 7 0.77 4.52 1.32
135 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19
136 INT213465 Transcription of Lep 4 0.68 2.11 1.15
137 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12
138 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
139 INT125147 Binding of Mc4r 10 0.41 3.55 1.08
140 INT331098 Negative_regulation of Positive_regulation of Mc4r 1 0.32 1.08 1.07
141 INT75846 Positive_regulation of MC4R 7 0.70 5.73 1.05
142 INT178024 Negative_regulation of Negative_regulation of Bdnf 6 0.37 5.31 0.99
143 INT148432 Negative_regulation of Binding of Bdnf 2 0.38 1.74 0.99
144 INT214113 Transcription of Ntrk2 2 0.72 1.84 0.96
145 INT172294 Binding of NPBWR1 1 0.41 0.27 0.96
146 INT138941 Regulation of Transcription of Ntrk2 2 0.47 0.76 0.95
147 INT82852 Localization of Npbwr1 1 0.47 0 0.95
148 INT113736 Negative_regulation of Positive_regulation of Mc4r 1 0.08 1.11 0.93
149 INT83229 Regulation of Regulation of Bdnf 6 0.45 4.62 0.92
150 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
151 INT155698 Regulation of Phosphorylation of Bdnf 1 0.39 0.4 0.86
152 INT228443 Regulation of Positive_regulation of Ntrk2 3 0.22 0.81 0.84
153 INT333883 Positive_regulation of Positive_regulation of Lep 2 0.46 1.06 0.83
154 INT191926 Negative_regulation of Lepr 13 0.48 17.68 0.8
155 INT111289 Regulation of MC4R 4 0.43 1 0.78
156 INT107101 Positive_regulation of Negative_regulation of Ntrk2 1 0.46 0.56 0.77
157 INT85018 Positive_regulation of Positive_regulation of Mc4r 3 0.24 0.11 0.76
158 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
159 INT228439 Positive_regulation of Regulation of Ntrk2 1 0.01 0.28 0.76
160 INT168557 Positive_regulation of Negative_regulation of Bdnf 3 0.44 1.87 0.75
161 INT213471 Positive_regulation of Localization of Lep 4 0.48 2.65 0.74
162 INT142239 Regulation of Phosphorylation of Ntrk2 1 0.45 0 0.74
163 INT355714 Regulation of Positive_regulation of Bdnf 1 0.39 0.34 0.73
164 INT284739 Positive_regulation of Gene_expression of Sh2b2 2 0.26 0.83 0.71
165 INT182036 Gene_expression of Sh2b2 2 0.13 1.74 0.67
166 INT47684 Negative_regulation of Negative_regulation of Bdnf 2 0.59 1.66 0.66
167 INT3501 Localization of Sh2b2 6 0.73 0.88 0.62
168 INT136139 Transcription of Mc4r 4 0.70 1.83 0.62
169 INT101484 Regulation of Positive_regulation of Lep 3 0.45 1.68 0.61
170 INT345957 Positive_regulation of Binding of Lep 2 0.38 2.03 0.6
171 INT123850 Negative_regulation of NPBWR1 1 0.43 0.46 0.6
172 INT83391 Negative_regulation of Transcription of Lep 1 0.43 0.34 0.6
173 INT284099 Negative_regulation of Binding of BDNF 1 0.42 0.75 0.6
174 INT231014 Negative_regulation of MC4R 4 0.43 5.52 0.58
175 INT150459 Positive_regulation of Phosphorylation of Ntrk2 2 0.42 0.24 0.52
176 INT210835 Phosphorylation of Mc4r 1 0.51 0.06 0.52
177 INT210837 Localization of Mc4r 5 0.73 0.87 0.51
178 INT69892 Regulation of Regulation of Ntrk2 1 0.62 0.14 0.49
179 INT47688 Negative_regulation of Positive_regulation of Ntrk2 2 0.41 1.79 0.47
180 INT102934 Positive_regulation of Regulation of Lep 2 0.50 0.55 0.42
181 INT228438 Negative_regulation of Regulation of Ntrk2 1 0.00 0.05 0.42
182 INT323765 Negative_regulation of Binding of Lep 1 0.37 0.91 0.42
183 INT355713 Regulation of Binding of Bdnf 1 0.39 0.16 0.41
184 INT197880 Binding of Sh2b2 2 0.19 0 0.38
185 INT128040 Positive_regulation of Binding of Ntrk2 1 0.49 0.32 0.37
186 INT126808 Localization of Mc4r 2 0.36 1.13 0.35
187 INT207195 Regulation of Regulation of Bdnf 1 0.25 0.92 0.35
188 INT249544 Regulation of Localization of BDNF 1 0.24 0.75 0.35
189 INT164029 Regulation of Gene_expression of Npbwr1 1 0.45 0.32 0.34
190 INT243808 Positive_regulation of Transcription of Sh2b2 1 0.29 0.86 0.33
191 INT243807 Transcription of Sh2b2 1 0.39 0.85 0.33
192 INT303962 Phosphorylation of Lep 2 0.80 5.2 0.31
193 INT213467 Negative_regulation of Localization of Lep 2 0.40 1.11 0.31
194 INT312681 Negative_regulation of Gene_expression of MC4R 1 0.35 0.15 0.31
195 INT214102 Positive_regulation of Transcription of Mc4r 1 0.49 0.4 0.3
196 INT313251 Negative_regulation of Positive_regulation of Sh2b2 1 0.12 0 0.29
197 INT69891 Positive_regulation of Negative_regulation of Ntrk2 1 0.50 0.08 0.26
198 INT284738 Positive_regulation of Localization of Sh2b2 1 0.09 0.6 0.26
199 INT211994 Positive_regulation of Binding of BDNF 1 0.49 0.69 0.26
200 INT273090 Protein_catabolism of Bdnf 1 0.56 0.08 0.25
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