GO:0019233

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Name sensory perception of pain
Categary Process
Go Slim No
Go Link GO:0019233
Unique Molecular Interactions 4789
Total Molecular Interactions 7143
Total Single Events 75215
Pain Genes Associated 119

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sensory perception of pain. They are ordered first by their pain relevance and then by number of times they were reported for sensory perception of pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT6078 Pomc Positive_regulation of Localization of Penk 13 0.51 0 15.49
3 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
4 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
5 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36
6 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
7 INT10161 Binding of Cck and Penk 6 0.53 0.97 11.15
8 INT6079 Pomc Positive_regulation of Penk 9 0.43 0 9.46
9 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
10 INT21276 Binding of Oprd1 and Penk 9 0.54 1.14 8.28
11 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22
12 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
13 INT140015 Avp Positive_regulation of Localization of Penk 3 0.63 3.48 6.63
14 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
15 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
16 INT31439 Penk Positive_regulation of Localization of Prl 8 0.55 0.23 6.24
17 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
18 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
19 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
20 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
21 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
22 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
23 INT9546 Binding of Adarb1 and Penk 5 0.03 0 5.1
24 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
25 INT211710 Binding of Mc1r and a 7 0.44 0.37 4.78
26 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
27 INT38217 Penk Regulation of Localization of Avp 2 0.38 0.56 4.45
28 INT30423 Penk Regulation of Localization of Ins1 4 0.26 0.77 4.42
29 INT36536 PRSS1 Positive_regulation of PENK 1 0.24 0.86 4.39
30 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
31 INT40114 Binding of OPRD1 and Oprm1 2 0.00 0 4.29
32 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
33 INT143270 Binding of Cnr1 and Gprasp1 4 0.54 0.64 4.18
34 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
35 INT31440 Penk Positive_regulation of Prl 7 0.76 0 4.1
36 INT2169 Penk Regulation of Localization of Prl 6 0.48 0 4.03
37 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
38 INT138959 Dbi Positive_regulation of Penk 1 0.01 3.05 3.99
39 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97
40 INT20456 Binding of Pomc and Penk 9 0.41 0.26 3.93
41 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
42 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9
43 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
44 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
45 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
46 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
47 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76
48 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
49 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
50 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
51 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
52 INT34534 Binding of Penk and Oprl1 4 0.37 0 3.64
53 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63
54 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
55 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
56 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
57 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
58 INT69770 Penk Negative_regulation of Pscs 1 0.11 0.22 3.39
59 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
60 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
61 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
62 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
63 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
64 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
65 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
66 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 0.31 0 3.14
67 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
68 INT30424 Penk Regulation of Localization of Sst 1 0.20 0 3.1
69 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
70 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
71 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
72 INT36535 PRSS1 Positive_regulation of Regulation of PENK 1 0.23 0.54 3.06
73 INT26677 Penk Regulation of Localization of Trh 5 0.50 0 3.05
74 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03
75 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
76 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
77 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
78 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96
79 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
80 INT41152 Binding of Penk and Slc3a1 3 0.12 0.11 2.91
81 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
82 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89
83 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
84 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
85 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
86 INT23280 PRSS1 Positive_regulation of Penk 1 0.05 1.53 2.74
87 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
88 INT30133 Binding of Cck and Penk 1 0.27 2.49 2.71
89 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
90 INT134294 Binding of Pdyn and Penk 1 0.23 0 2.69
91 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
92 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68
93 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67
94 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
95 INT70946 Penk Positive_regulation of Hpse 1 0.34 0 2.65
96 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
97 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62
98 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
99 INT30345 Pomc Regulation of Localization of Penk 3 0.31 0 2.61
100 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
101 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58
102 INT111789 Cck Regulation of Gene_expression of Penk 1 0.49 1.68 2.57
103 INT111786 Penk Regulation of Gene_expression of Cck 1 0.49 1.66 2.55
104 INT104219 SCD Positive_regulation of Cnr1 1 0.00 2.67 2.54
105 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54
106 INT104218 SCD Positive_regulation of CNR2 1 0.01 2.67 2.54
107 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 0.78 0.16 2.53
108 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
109 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
110 INT14687 Binding of Penk and Ppt1 1 0.41 0 2.46
111 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46
112 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
113 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
114 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
115 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
116 INT143272 Binding of CNR1 and Gprasp1 1 0.01 0.17 2.42
117 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
118 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
119 INT107165 Binding of Gabrg1 and Trpv1 2 0.01 0.16 2.34
120 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
121 INT88730 Binding of OPRM1 and Mop3 1 0.00 0 2.34
122 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
123 INT108987 Ngf Regulation of Gene_expression of Sit1 1 0.00 1.46 2.32
124 INT154226 Positive_regulation of Oprk1 Negative_regulation of Negative_regulation of Oprm1 1 0.28 0.07 2.32
125 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 0.00 0.08 2.31
126 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
127 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
128 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
129 INT91860 Npy Regulation of Npy1r 2 0.28 1.13 2.24
130 INT198958 Cnr1 Positive_regulation of Kcnj9 1 0.00 0.15 2.24
131 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
132 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
133 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
134 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18
135 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
136 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
137 INT49242 Binding of Mc1r and Pomc 10 0.38 3.79 2.15
138 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
139 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
140 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
141 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
142 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13
143 INT351380 Ngf Regulation of TPM1 1 0.44 2.17 2.11
144 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
145 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
146 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
147 INT51198 Positive_regulation of Binding of OPRM1 and PDYN 2 0.18 0.3 2.08
148 INT51199 Binding of OPRM1 and PDYN 2 0.13 0.3 2.08
149 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
150 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
151 INT331105 Vmn1r71 Negative_regulation of Mc1r 1 0.04 0.64 2.07
152 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
153 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06
154 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
155 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
156 INT167530 Phax Regulation of Gene_expression of Trpv1 1 0.16 0.86 2.05
157 INT18355 Penk Positive_regulation of Localization of Sst 1 0.31 0 2.04
158 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
159 INT21261 Penk Negative_regulation of Npr1 1 0.02 0 2
160 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
161 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
162 INT58678 Binding of Penk and Abat 2 0.40 1.39 1.97
163 INT2653 Slc3a1 Regulation of Penk 3 0.04 0.37 1.96
164 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95
165 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
166 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
167 INT37882 Penk Positive_regulation of LOC100366054 1 0.08 0.35 1.93
168 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93
169 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
170 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92
171 INT264928 Binding of Cnr1 and Hrh1 1 0.01 1.61 1.92
172 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
173 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
174 INT31438 Penk Positive_regulation of Localization of Pomc 1 0.18 0 1.9
175 INT169498 Binding of Oprm1 and Mirlet7a-1 1 0.32 0 1.9
176 INT161079 Mcs18 Negative_regulation of Trpv1 1 0.40 0.82 1.9
177 INT113572 Binding of DMRT1 and OPRM1 1 0.01 0 1.9
178 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
179 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
180 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
181 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88
182 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
183 INT153582 Binding of Oprm1 and Hint1 1 0.01 0 1.87
184 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
185 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 0.09 0 1.86
186 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
187 INT75069 Penk Regulation of Gene_expression of Pkhd1l1 1 0.09 0 1.85
188 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85
189 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
190 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84
191 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
192 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
193 INT40239 Penk Regulation of Avp 1 0.07 0 1.84
194 INT40238 Penk Regulation of Oxt 1 0.04 0 1.83
195 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
196 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
197 INT169502 Mirlet7a-1 Regulation of Oprm1 1 0.53 0 1.81
198 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
199 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
200 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78

Single Events

The table below shows the top 100 pain related interactions that have been reported for sensory perception of pain. They are ordered first by their pain relevance and then by number of times they were reported in sensory perception of pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59
2 INT292 Localization of Penk 876 0.81 88.44 669.14
3 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59
4 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87
5 INT797 Regulation of Penk 812 0.62 111.13 542.24
6 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29
7 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42
8 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81
9 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42
10 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26
11 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71
12 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
13 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36
14 INT1396 Binding of Penk 355 0.48 22.79 269.65
15 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59
16 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
17 INT6406 Binding of Oprm1 280 0.48 40.54 226.26
18 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
19 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
20 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
21 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07
22 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71
23 INT4803 Transcription of Penk 435 0.72 59.09 182.4
24 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85
25 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1
26 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
27 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28
28 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
29 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
30 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88
31 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
32 INT4658 Binding of OPRM1 188 0.48 25.96 136.24
33 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4
34 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
35 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
36 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75
37 INT2555 Positive_regulation of Localization of Penk 116 0.70 24.35 119.73
38 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
39 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34
40 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58
41 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
42 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66
43 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03
44 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
45 INT293 Protein_catabolism of Penk 161 1.00 11.71 98.45
46 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97
47 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49
48 INT38731 Localization of Trpv1 138 0.81 52.73 90.49
49 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37
50 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7
51 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
52 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27
53 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
54 INT4830 Binding of Trpv1 158 0.48 45.11 84.2
55 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
56 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
57 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57
58 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49
59 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
60 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
61 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
62 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7
63 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23
64 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
65 INT3034 Localization of Ngf 126 0.81 50.81 72.84
66 INT5852 Gene_expression of Penk 167 0.78 44.44 71.13
67 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15
68 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26
69 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33
70 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
71 INT5573 Negative_regulation of Gene_expression of Penk 113 0.59 21.83 64.66
72 INT8733 Localization of Oprm1 61 0.75 7.55 64.61
73 INT96622 Localization of Trpv1 110 0.81 59.82 63.25
74 INT65730 Gene_expression of Cnr2 129 0.78 60.15 63.1
75 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84
76 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
77 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
78 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
79 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83
80 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
81 INT5819 Regulation of Localization of Penk 64 0.62 6.69 57.68
82 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65
83 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
84 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59
85 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
86 INT2421 Positive_regulation of Positive_regulation of Penk 97 0.69 13.38 55.32
87 INT37219 Gene_expression of TACR1 56 0.78 32.4 54.16
88 INT6073 Negative_regulation of Localization of Penk 63 0.59 8.67 53.95
89 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
90 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
91 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04
92 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
93 INT69484 Positive_regulation of Gene_expression of OPRM1 75 0.70 12.86 52.27
94 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96
95 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75
96 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51
97 INT8690 Localization of Tac1 71 0.80 22.98 50.75
98 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67
99 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
100 INT7287 Positive_regulation of Transcription of Penk 103 0.70 19.81 50.37
101 INT76620 Gene_expression of Cnr2 93 0.78 34.7 50.14
102 INT62426 Gene_expression of Mc1r 127 0.78 42.99 48.01
103 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
104 INT62521 Phosphorylation of Oprm1 44 0.82 2.66 47.45
105 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
106 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
107 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
108 INT8713 Regulation of Tac1 56 0.60 25.29 45.94
109 INT4776 Localization of TAC1 82 0.78 16.89 45.21
110 INT14853 Negative_regulation of Tac1 80 0.59 30.87 45.06
111 INT1564 Localization of OPRM1 41 0.80 8.03 44.67
112 INT63383 Binding of Cnr1 77 0.48 22.28 44.61
113 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41
114 INT98498 Binding of Trpv1 75 0.48 33.67 44.4
115 INT19078 Binding of Ngf 78 0.48 31.03 44.33
116 INT4850 Binding of Tac1 57 0.47 14.25 42.17
117 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
118 INT4862 Localization of PENK 62 0.81 11.57 40.28
119 INT49643 Gene_expression of Bdkrb1 39 0.78 46.49 40.21
120 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
121 INT16194 Binding of CNR1 82 0.48 20.75 39.59
122 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
123 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
124 INT20210 Localization of Ngf 69 0.79 46.22 38.57
125 INT4925 Binding of Tacr1 57 0.48 17.39 38.38
126 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37
127 INT65125 Gene_expression of Tacr1 81 0.77 23.9 38.35
128 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02
129 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92
130 INT88081 Negative_regulation of Gene_expression of Oprm1 45 0.59 16.56 37.5
131 INT11246 Binding of Grin1 65 0.48 14.53 36.93
132 INT80075 Regulation of Gene_expression of Trpv1 55 0.62 32.42 36.88
133 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
134 INT12608 Regulation of CNR1 62 0.60 24.36 36.02
135 INT8837 Positive_regulation of TAC1 59 0.67 21.94 35.97
136 INT77407 Regulation of Gene_expression of OPRM1 51 0.62 12.58 35.75
137 INT98521 Gene_expression of Accn2 52 0.74 23.45 35.09
138 INT76531 Transcription of Trpv1 62 0.72 23.69 34.77
139 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
140 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
141 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69
142 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52
143 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28
144 INT1457 Negative_regulation of Binding of Penk 40 0.57 0.25 34.24
145 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
146 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05
147 INT50308 Binding of Cnr1 61 0.48 14.41 33.52
148 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
149 INT7286 Regulation of Transcription of Penk 81 0.62 9.25 33.45
150 INT21560 Positive_regulation of Binding of Oprm1 30 0.50 7.16 32.95
151 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
152 INT4727 Regulation of TAC1 60 0.47 6.74 32.83
153 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
154 INT7692 Positive_regulation of PENK 71 0.70 20.34 32.54
155 INT1711 Negative_regulation of Positive_regulation of Penk 54 0.59 6.55 32.42
156 INT610 Regulation of PENK 47 0.62 14.17 31.55
157 INT22239 Negative_regulation of TAC1 52 0.57 12.96 31.41
158 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
159 INT5418 Negative_regulation of Alox5 108 0.57 42.09 31.17
160 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16
161 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46
162 INT11279 Positive_regulation of Penk 65 0.70 18.72 30.29
163 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27
164 INT69483 Transcription of OPRM1 45 0.72 7.31 30.22
165 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11
166 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
167 INT9053 Negative_regulation of ALOX5 97 0.58 40.34 29.94
168 INT16769 Positive_regulation of Positive_regulation of Oprm1 31 0.57 8.29 29.66
169 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
170 INT49431 Phosphorylation of OPRM1 31 0.82 2.2 29.09
171 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
172 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
173 INT10684 Negative_regulation of Protein_catabolism of Penk 41 0.59 2.33 28.63
174 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
175 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07
176 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
177 INT111359 Localization of Cnr1 55 0.81 11.25 27.41
178 INT75418 Negative_regulation of Cnr1 41 0.59 14.65 27.28
179 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19
180 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
181 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9
182 INT28834 Positive_regulation of Bdkrb1 38 0.69 30.48 26.89
183 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75
184 INT76621 Positive_regulation of Cnr2 32 0.69 17.77 26.57
185 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
186 INT63769 Regulation of Ngf 44 0.62 21.82 25.84
187 INT11773 Gene_expression of Tac1 56 0.77 10 25.72
188 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68
189 INT112036 Phosphorylation of Trpv1 51 0.82 18.59 25.6
190 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
191 INT8779 Binding of TAC1 50 0.47 11.19 25.57
192 INT9886 Gene_expression of Ptgs1 92 0.77 40.66 25.31
193 INT103320 Positive_regulation of Positive_regulation of Trpv1 44 0.70 27.73 25.28
194 INT5851 Positive_regulation of Gene_expression of Penk 52 0.70 14.57 25.05
195 INT92105 Transcription of Trpv1 47 0.71 27.47 25.01
196 INT81496 Gene_expression of CNR2 68 0.75 30.04 24.92
197 INT74377 Regulation of Cnr1 38 0.59 16.93 24.77
198 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
199 INT48240 Binding of Ngf 46 0.46 23.51 24.42
200 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
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