GO:0019371

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Name cyclooxygenase pathway
Categary Process
Go Slim No
Go Link GO:0019371
Unique Molecular Interactions 297
Total Molecular Interactions 348
Total Single Events 9407
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cyclooxygenase pathway. They are ordered first by their pain relevance and then by number of times they were reported for cyclooxygenase pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54
2 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37
3 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
4 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
5 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
6 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 0.01 0.81 1.31
7 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27
8 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
9 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
10 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
11 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
12 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
13 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
14 INT61037 Och Positive_regulation of Ptgs1 1 0.00 0 0.95
15 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9
16 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86
17 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84
18 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79
19 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
20 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
21 INT119314 Ptgs1 Regulation of Gene_expression of Ptger2 1 0.01 0.6 0.73
22 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71
23 INT114735 Mtx1 Regulation of Ptgs1 1 0.01 0.31 0.69
24 INT71942 Negative_regulation of PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.62
25 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 1 0.03 0.2 0.62
26 INT55672 Ptgs1 Positive_regulation of Gene_expression of Ik 1 0.03 0.75 0.61
27 INT71944 PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.61
28 INT137247 Slc6a14 Negative_regulation of Ptgs2 2 0.19 1.38 0.58
29 INT137248 Slc6a14 Negative_regulation of Gene_expression of Ptgs2 1 0.19 1.32 0.58
30 INT125546 Arsa Negative_regulation of Gene_expression of PTGS2 1 0.00 0.53 0.58
31 INT87294 SERPINA3 Negative_regulation of PTGS2 1 0.25 0.6 0.58
32 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
33 INT71943 Regulation of ZNF697 Negative_regulation of PTGS2 1 0.01 0.07 0.54
34 INT129912 Skiv2l Negative_regulation of Gene_expression of PTGS2 1 0.00 0.87 0.54
35 INT76200 CASP1 Positive_regulation of Gene_expression of PTGS1 1 0.05 0.16 0.54
36 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54
37 INT71945 ZNF697 Negative_regulation of PTGS2 1 0.01 0.07 0.53
38 INT69882 Ptger2 Positive_regulation of Gene_expression of Ptgs2 1 0.19 0.6 0.52
39 INT116541 Binding of Ptgs2 and ZNF398 1 0.00 0.68 0.52
40 INT105849 Il1b Positive_regulation of Positive_regulation of Ptgs1 1 0.07 0.38 0.51
41 INT78590 Nos2 Positive_regulation of PTGS1 2 0.00 0.85 0.5
42 INT150205 Tnrc6a Negative_regulation of PTGS2 1 0.00 0.42 0.49
43 INT135584 CSF2 Regulation of PTGS2 1 0.06 1.28 0.49
44 INT150788 ZNF398 Regulation of PTGS2 1 0.02 0.5 0.48
45 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48
46 INT131809 Nfkb1 Positive_regulation of Gene_expression of Ptgs1 1 0.12 0.73 0.48
47 INT129551 Sag Negative_regulation of Gene_expression of Ptgs1 1 0.08 0.88 0.48
48 INT62164 Il1b Positive_regulation of PTGS2 1 0.00 0.49 0.47
49 INT62163 Il1b Positive_regulation of Positive_regulation of PTGS2 1 0.00 0.49 0.47
50 INT145434 Binding of HMOX1 and PTGS2 1 0.02 0.41 0.47
51 INT145436 Binding of HMOX2 and PTGS2 1 0.02 0.41 0.47
52 INT127662 Negative_regulation of PDE4A Negative_regulation of Gene_expression of PTGS2 1 0.15 0.75 0.47
53 INT103026 Ptgis Positive_regulation of Ptgs1 1 0.02 0.42 0.46
54 INT103029 Calca Positive_regulation of Positive_regulation of Ptgs1 1 0.12 0.41 0.46
55 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
56 INT53470 Acsm3 Regulation of Ptgs1 1 0.15 0 0.42
57 INT53469 Negative_regulation of Acsm3 Regulation of Ptgs1 1 0.24 0 0.42
58 INT53471 Binding of Ptgs1 and Acsm3 1 0.17 0 0.41
59 INT91107 Positive_regulation of Ptgs1 Positive_regulation of Localization of Crh 1 0.00 0.56 0.41
60 INT106505 Binding of Ptgds and Ptgs2 1 0.01 0.93 0.39
61 INT200096 Negative_regulation of Il1a Negative_regulation of Gene_expression of Ptgs2 1 0.00 1.45 0.39
62 INT50553 Negative_regulation of Ptgs1 Negative_regulation of Gene_expression of Tbxa2r 1 0.02 1.37 0.38
63 INT157171 Binding of PTGS2 and Pla2g1b 1 0.02 0.26 0.37
64 INT74244 Ptgs1 Regulation of Positive_regulation of Penk 1 0.09 0.19 0.37
65 INT93694 Binding of Hspa8 and Ptgs1 1 0.30 0.79 0.36
66 INT167045 TRPA1 Regulation of PTGS1 1 0.19 0.1 0.35
67 INT278766 HOXA9 Positive_regulation of Gene_expression of PTGS2 1 0.43 1.28 0.35
68 INT278749 NUP98 Positive_regulation of Gene_expression of PTGS2 1 0.46 1.28 0.35
69 INT89501 Il6 Positive_regulation of Ptgs2 1 0.01 1.07 0.35
70 INT25354 Chi3l1 Negative_regulation of Ptgs1 1 0.00 0.39 0.34
71 INT89505 Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
72 INT5388 PTGS1 Negative_regulation of APRT 1 0.21 0.4 0.34
73 INT134303 Cpox Negative_regulation of PTGS2 1 0.00 0.77 0.34
74 INT89502 Positive_regulation of Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
75 INT68557 ZNF697 Negative_regulation of PTGS1 1 0.02 0.59 0.33
76 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
77 INT52700 Prkcg Positive_regulation of Ptgs2 1 0.12 0.3 0.32
78 INT108879 Negative_regulation of PTGS2 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.43 0.31
79 INT64859 Negative_regulation of PTGS1 Negative_regulation of PTGS2 1 0.07 0.05 0.31
80 INT116594 Negative_regulation of PTGS2 Negative_regulation of Gene_expression of IL6 1 0.22 0.45 0.31
81 INT213062 PTGS1 Regulation of Gene_expression of MMP9 1 0.04 0.25 0.3
82 INT139044 AKR1B1 Regulation of Gene_expression of PTGS2 1 0.09 0.37 0.3
83 INT156084 Binding of PTGS2 and AKR1C3 1 0.02 0.31 0.3
84 INT156082 Binding of PTGS1 and AKR1C3 1 0.01 0.31 0.3
85 INT65539 PTGS1 Positive_regulation of Positive_regulation of Nfkb1 1 0.06 0.18 0.3
86 INT62207 Binding of PTGS1 and PTGS2 3 0.06 0.07 0.29
87 INT74942 HGF Positive_regulation of PTGS1 1 0.11 0.25 0.29
88 INT265467 HRAS Negative_regulation of Gene_expression of PTGS2 1 0.01 0.84 0.29
89 INT65540 Gene_expression of PTGS1 Positive_regulation of Positive_regulation of Nfkb1 1 0.05 0.17 0.29
90 INT81479 Binding of Ptgs1 and ZNF398 1 0.00 0.17 0.28
91 INT122000 Negative_regulation of PTGS1 Positive_regulation of Gene_expression of TNF 1 0.23 0.11 0.28
92 INT102335 DFP Negative_regulation of Ptgs1 1 0.04 0.31 0.28
93 INT243214 Myst2 Negative_regulation of Gene_expression of Ptgs2 1 0.01 1.4 0.28
94 INT158266 Olr1745 Negative_regulation of Ptgs1 1 0.01 0.52 0.27
95 INT91751 Binding of PTGS2 and Hmox1 1 0.00 0.21 0.27
96 INT142447 PTGS2 Regulation of Gene_expression of PTGIS 1 0.30 0.24 0.27
97 INT107392 PTGS2 Positive_regulation of PTGS1 2 0.31 1.01 0.26
98 INT114069 Negative_regulation of Agtr2 Positive_regulation of Ptgs2 1 0.08 0.49 0.26
99 INT69120 MOCS1 Regulation of PTGS2 1 0.00 0.39 0.26
100 INT96402 Binding of PTGS2 and TBXAS1 1 0.02 0.32 0.26
101 INT64860 PTGS1 Negative_regulation of PTGS2 1 0.07 0 0.26
102 INT96401 Binding of PTGER1 and PTGS2 1 0.00 0.32 0.26
103 INT53951 Negative_regulation of Trib3 Negative_regulation of Gene_expression of Ptgs1 1 0.01 0.43 0.26
104 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25
105 INT66257 Negative_regulation of Ptgs1 Positive_regulation of Gene_expression of Tnf 1 0.03 0.44 0.25
106 INT76224 Ptgs1 Regulation of Gene_expression of PECAM1 1 0.00 0.25 0.25
107 INT38711 CYSLTR1 Positive_regulation of Gene_expression of PTGS1 1 0.08 0.14 0.25
108 INT158621 Binding of SIGMAR1 and Sphk1 1 0.01 0 0.25
109 INT102625 IL6 Regulation of Gene_expression of PTGS2 1 0.11 0.29 0.24
110 INT126551 Agt Positive_regulation of Gene_expression of Ptgs1 1 0.25 0.92 0.24
111 INT136798 Spp1 Regulation of Gene_expression of PTGS2 1 0.08 0.65 0.24
112 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24
113 INT166663 Mpzl2 Negative_regulation of Positive_regulation of Ptgs2 1 0.29 0.3 0.24
114 INT102617 PTAFR Regulation of Gene_expression of PTGS2 1 0.12 0.29 0.24
115 INT132382 Nos2 Positive_regulation of PTGS2 1 0.02 0.1 0.23
116 INT325028 TNF Negative_regulation of Ptgs1 1 0.00 1.79 0.23
117 INT272143 PTAFR Positive_regulation of Gene_expression of PTGS2 1 0.12 1.59 0.23
118 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23
119 INT145014 Positive_regulation of GAST Positive_regulation of PTGS2 1 0.31 0.51 0.22
120 INT149882 Binding of Ptgs1 and Ptges 1 0.01 0.15 0.22
121 INT133164 Ptgs2 Regulation of Tnf 1 0.14 0.98 0.22
122 INT145012 GAST Positive_regulation of PTGS2 1 0.42 0.51 0.22
123 INT112134 Gast Positive_regulation of Gene_expression of Ptgs2 1 0.28 0.19 0.21
124 INT69318 ST3GAL4 Positive_regulation of Gene_expression of PTGS2 1 0.35 0.09 0.21
125 INT112136 Egf Positive_regulation of Gene_expression of Ptgs2 1 0.21 0.19 0.21
126 INT283747 Tbs1 Positive_regulation of Ptgs2 1 0.00 0 0.2
127 INT231639 Binding of PTGER2 and PTGS2 1 0.00 0.44 0.19
128 INT117517 PROC Positive_regulation of PTGS2 1 0.01 0.61 0.19
129 INT136462 Negative_regulation of Ptgs1 Negative_regulation of Gene_expression of Sp1 1 0.01 0.65 0.19
130 INT79651 PTGS2 Positive_regulation of Phosphorylation of NR3C1 1 0.07 0.1 0.19
131 INT206089 Negative_regulation of FOSB Negative_regulation of Gene_expression of PTGS2 1 0.00 0.97 0.19
132 INT139015 STAT1 Negative_regulation of Gene_expression of PTGS2 1 0.01 0.36 0.19
133 INT73332 IL1B Positive_regulation of Transcription of PTGS2 1 0.44 0.54 0.18
134 INT127503 Mpz Positive_regulation of Ptgs1 1 0.14 0.9 0.18
135 INT73331 PTAFR Positive_regulation of Transcription of PTGS2 1 0.13 0.54 0.18
136 INT255431 Airn Negative_regulation of Gene_expression of Ptgs1 1 0.00 0.66 0.17
137 INT152024 Ptgs1 Regulation of Fgf2 1 0.04 0.9 0.17
138 INT93693 Positive_regulation of Binding of Hspa8 and Ptgs1 1 0.31 0.38 0.17
139 INT119130 Binding of Nos2 and Ptgs2 1 0.33 0.07 0.17
140 INT354819 Binding of Cpox and Ptgs2 1 0.02 0.45 0.16
141 INT328484 Ptgs1 Positive_regulation of Ros1 1 0.00 0.58 0.16
142 INT69317 PTGS2 Positive_regulation of Gene_expression of PTGS1 1 0.42 0.09 0.16
143 INT141753 Nfkb1 Regulation of Ptgs2 1 0.16 1.18 0.16
144 INT146745 UGCG Positive_regulation of Gene_expression of PTGS2 1 0.23 0.1 0.16
145 INT63453 Positive_regulation of PTGS1 Positive_regulation of Gene_expression of PLEKHM1 1 0.05 0.09 0.16
146 INT141754 Nfkb1 Regulation of Positive_regulation of Ptgs2 1 0.16 1.21 0.16
147 INT327556 Ptgs1 Regulation of Gene_expression of Ptger2 1 0.01 0.85 0.15
148 INT176621 PTGS2 Regulation of Gene_expression of PTGER2 1 0.00 0.09 0.15
149 INT327558 Ptgs1 Regulation of Gene_expression of Ros1 1 0.01 0.87 0.15
150 INT87710 MYB Regulation of PTGS2 1 0.28 0.64 0.15
151 INT92342 Zfp697 Negative_regulation of Ptgs2 1 0.02 0.63 0.15
152 INT50500 Edn1 Positive_regulation of PTGS1 1 0.00 0.07 0.14
153 INT138321 PPA1 Positive_regulation of Gene_expression of PTGS2 1 0.02 0.09 0.14
154 INT141111 Sftpa1 Positive_regulation of Ptgs2 1 0.64 0.3 0.14
155 INT328851 Binding of PTGS2 and ZNF434 1 0.00 0.7 0.14
156 INT141112 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 0.39 0.31 0.14
157 INT134405 Binding of PTGS1 and HPGDS 1 0.01 0.33 0.14
158 INT102380 Ptgs1 Negative_regulation of Binding of Tbxa2r 1 0.04 0.16 0.14
159 INT81983 IL1A Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.27 0.13
160 INT46268 MAPKAP1 Regulation of PTGS1 1 0.13 0 0.13
161 INT67619 Inpp5k Negative_regulation of Ptgs1 1 0.03 0.5 0.13
162 INT306270 CCL4 Positive_regulation of Transcription of PTGS2 1 0.34 0.31 0.12
163 INT173129 PTGS2 Regulation of IER3 1 0.01 0.36 0.12
164 INT306262 NFKB1 Positive_regulation of Transcription of PTGS2 1 0.42 0.31 0.12
165 INT63521 Negative_regulation of Ptgs2 Negative_regulation of Gene_expression of Fos 1 0.66 0.1 0.12
166 INT117568 Dspp Negative_regulation of Ptgs2 1 0.11 0.13 0.12
167 INT147073 NFKB1 Regulation of PTGS2 1 0.37 0 0.11
168 INT133361 FABP6 Negative_regulation of PTGS2 1 0.01 0.07 0.11
169 INT52701 Slc3a1 Positive_regulation of Ptgs2 1 0.06 0.27 0.11
170 INT52702 Capza2 Positive_regulation of Ptgs2 1 0.00 0.27 0.11
171 INT294454 KLK4 Negative_regulation of PTGS2 1 0.01 0 0.1
172 INT87922 Gm7869 Negative_regulation of Ptgs2 1 0.01 0.56 0.1
173 INT223754 Tlr4 Positive_regulation of Ptgs1 1 0.04 0 0.1
174 INT87921 Gm7869 Negative_regulation of Ptgs1 1 0.01 0.55 0.1
175 INT327557 Pla2g4a Positive_regulation of Phosphorylation of Ptgs2 1 0.14 1.03 0.1
176 INT327559 Pla2g4a Positive_regulation of Gene_expression of Ptgs2 1 0.14 1 0.09
177 INT268325 Lep Positive_regulation of Ptgs2 1 0.09 0.39 0.08
178 INT140895 PTGS2 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.07 0.07
179 INT98715 HGF Positive_regulation of Gene_expression of PTGS2 1 0.02 1.03 0.07
180 INT341882 Positive_regulation of Oxtr Positive_regulation of Positive_regulation of Ptgs2 1 0.02 0.11 0.05
181 INT17850 Binding of PTGS2 and Ptgs2 1 0.00 0.08 0.04
182 INT17851 Negative_regulation of Binding of PTGS2 and Ptgs2 1 0.00 0.08 0.04
183 INT331157 Ptgis Positive_regulation of Ptgs2 1 0.04 0.77 0.03
184 INT197784 Binding of Cpe and Ptgs1 1 0.20 0 0.03
185 INT287676 Negative_regulation of Sphk1 Negative_regulation of Pik3r1 1 0.14 0.42 0
186 INT346838 ZNF434 Regulation of PTGS2 1 0.01 0.34 0
187 INT121545 Mif Negative_regulation of Regulation of Ptgs2 1 0.13 0.15 0
188 INT346836 MECP2 Regulation of PTGS2 1 0.00 0.34 0
189 INT352066 Binding of PTGS2 and PTGES2 1 0.04 0 0
190 INT287673 Negative_regulation of Sphk1 Negative_regulation of Akt1 1 0.20 0.42 0
191 INT149883 Agtr2 Positive_regulation of Gene_expression of Ptgs2 1 0.06 0.31 0
192 INT227486 pk Positive_regulation of Gene_expression of Ptgs1 1 0.03 0.17 0
193 INT343163 ACSL4 Regulation of Gene_expression of PTGS2 1 0.08 0.5 0
194 INT158506 COX5A Negative_regulation of PTGS1 1 0.06 0.18 0
195 INT352064 Binding of PTGS2 and HPGDS 1 0.20 0 0
196 INT165863 Binding of HSPG2 and PTGS2 1 0.01 0.19 0
197 INT87649 Ptgs1 Positive_regulation of Positive_regulation of Penk 1 0.00 0 0
198 INT352065 Binding of PTGDS and PTGS2 1 0.28 0 0
199 INT143293 Negative_regulation of Nfkb1 Negative_regulation of Gene_expression of PTGS2 1 0.00 0 0
200 INT166070 PTGS2 Regulation of VEGFA 1 0.29 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cyclooxygenase pathway. They are ordered first by their pain relevance and then by number of times they were reported in cyclooxygenase pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26
2 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
3 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6
4 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
5 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58
6 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97
7 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
8 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
9 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5
10 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
11 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04
12 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
13 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
14 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41
15 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46
16 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
17 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18
18 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95
19 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85
20 INT9886 Gene_expression of Ptgs1 92 0.77 40.66 25.31
21 INT21503 Binding of Ptgs1 45 0.48 15.6 22.29
22 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
23 INT17848 Binding of PTGS2 70 0.46 32.1 20.6
24 INT45840 Positive_regulation of Gene_expression of Ptgs1 35 0.50 16.07 20.49
25 INT9197 Binding of PTGS1 44 0.48 18.48 16.26
26 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44
27 INT53080 Positive_regulation of Ptgs1 42 0.42 23.58 14.37
28 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39
29 INT12992 Negative_regulation of Gene_expression of Ptgs1 33 0.42 20.47 11.77
30 INT20457 Regulation of Ptgs1 23 0.48 11.63 11.56
31 INT787 Localization of Ptgs1 31 0.80 12.36 11.55
32 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39
33 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
34 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39
35 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
36 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53
37 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27
38 INT12991 Negative_regulation of Gene_expression of PTGS1 28 0.41 13.39 8.9
39 INT23264 Negative_regulation of Positive_regulation of Ptgs1 16 0.39 8.47 8.9
40 INT52442 Binding of Ptgs1 16 0.35 9.05 8.78
41 INT6573 Regulation of Negative_regulation of Ptgs1 19 0.45 6.16 8.71
42 INT20234 Regulation of Gene_expression of Ptgs1 11 0.44 6.55 7.72
43 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
44 INT49751 Negative_regulation of Positive_regulation of PTGS1 12 0.45 4.73 7.23
45 INT90097 Localization of PTGS2 15 0.69 6.14 6.63
46 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52
47 INT25130 Positive_regulation of Negative_regulation of Ptgs1 14 0.50 5.07 6.29
48 INT67656 Positive_regulation of Positive_regulation of PTGS2 12 0.46 4.83 6.17
49 INT17370 Negative_regulation of Negative_regulation of Ptgs1 16 0.22 6.5 6.12
50 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
51 INT48004 Positive_regulation of Negative_regulation of PTGS1 12 0.49 4.07 5.87
52 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86
53 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71
54 INT50491 Regulation of Gene_expression of PTGS1 17 0.47 6 5.4
55 INT39256 Localization of PTGS1 17 0.74 6.62 5.1
56 INT62500 Transcription of Ptgs1 10 0.56 4.54 4.52
57 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5
58 INT52616 Negative_regulation of Positive_regulation of PTGS2 13 0.43 4.95 4.13
59 INT115773 Negative_regulation of Localization of Ptgs2 6 0.43 2.99 3.81
60 INT53200 Binding of Ptgs2 11 0.48 5.08 3.54
61 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11
62 INT77615 Positive_regulation of Negative_regulation of Ptgs1 6 0.50 1.55 3.11
63 INT90402 Positive_regulation of Gene_expression of Ptgs1 13 0.31 4.83 2.88
64 INT68505 Positive_regulation of Negative_regulation of PTGS2 8 0.49 2.26 2.76
65 INT138437 Gene_expression of Sphk1 23 0.65 10.01 2.61
66 INT27607 Localization of Ptgs1 7 0.59 3.22 2.6
67 INT127176 Transcription of Ptgs2 8 0.58 4.68 2.58
68 INT34969 Negative_regulation of Binding of Ptgs1 4 0.37 1.55 2.55
69 INT17846 Binding of Ptgs2 8 0.32 4.66 2.48
70 INT70197 Negative_regulation of Positive_regulation of Ptgs1 6 0.24 2.61 2.44
71 INT53476 Positive_regulation of Localization of Ptgs1 6 0.49 2.88 2.35
72 INT9887 Negative_regulation of Gene_expression of Ptgs1 7 0.42 2.94 2.3
73 INT78958 Regulation of Negative_regulation of Ptgs2 6 0.42 2.61 2.3
74 INT88241 Positive_regulation of Positive_regulation of Ptgs1 3 0.45 1.71 2.25
75 INT54823 Phosphorylation of PTGS1 4 0.51 1.61 2.14
76 INT32557 Negative_regulation of Negative_regulation of PTGS1 8 0.43 3.44 2.1
77 INT97579 Negative_regulation of Localization of PTGS2 2 0.08 2.37 1.99
78 INT101985 Positive_regulation of Positive_regulation of Ptgs1 4 0.15 4.13 1.98
79 INT77805 Regulation of Gene_expression of Ptgs2 6 0.51 2.7 1.92
80 INT52691 Positive_regulation of Transcription of Ptgs2 5 0.44 3 1.9
81 INT138439 Positive_regulation of Gene_expression of Sphk1 14 0.48 5.93 1.86
82 INT154816 Negative_regulation of Sphk1 19 0.41 11.38 1.84
83 INT53812 Regulation of Gene_expression of Ptgs1 5 0.38 0.89 1.78
84 INT64915 Regulation of Negative_regulation of PTGS1 4 0.20 1.81 1.76
85 INT78956 Regulation of Transcription of Ptgs1 3 0.35 1.42 1.7
86 INT59077 Transcription of PTGS1 11 0.43 2.37 1.65
87 INT60857 Negative_regulation of Regulation of Ptgs1 1 0.07 2.22 1.61
88 INT149622 Positive_regulation of Transcription of Ptgs2 3 0.28 2.48 1.46
89 INT190768 Regulation of Positive_regulation of Ptgs2 1 0.04 1.2 1.41
90 INT86823 Regulation of Transcription of PTGS2 3 0.19 1.48 1.4
91 INT89209 Negative_regulation of Binding of Ptgs1 6 0.06 2.7 1.39
92 INT73260 Regulation of Positive_regulation of PTGS1 3 0.26 2.65 1.37
93 INT135658 Phosphorylation of Ptgs2 2 0.23 1.39 1.34
94 INT101026 Positive_regulation of Negative_regulation of Ptgs2 2 0.35 1.01 1.23
95 INT179372 Positive_regulation of Localization of PTGS2 2 0.38 0.35 1.21
96 INT138434 Positive_regulation of Sphk1 10 0.48 2.18 1.18
97 INT59078 Positive_regulation of Transcription of PTGS2 5 0.69 2.36 1.17
98 INT130198 Negative_regulation of Binding of PTGS1 3 0.34 2.6 1.16
99 INT62981 Protein_catabolism of PTGS2 5 0.78 1.09 1.11
100 INT64862 Negative_regulation of Negative_regulation of PTGS2 3 0.36 0.76 1.09
101 INT70505 Positive_regulation of Positive_regulation of Ptgs2 4 0.49 2.22 1.08
102 INT78353 Positive_regulation of Positive_regulation of PTGS1 4 0.27 0.95 1.06
103 INT83647 Negative_regulation of Negative_regulation of Ptgs2 1 0.28 1.97 1.05
104 INT64177 Negative_regulation of Transcription of PTGS2 4 0.41 1.99 1.03
105 INT63284 Transcription of Ptgs1 5 0.66 1.34 0.97
106 INT62980 Protein_catabolism of Ptgs1 3 0.59 0.93 0.97
107 INT68265 Positive_regulation of Negative_regulation of Ptgs2 3 0.46 0.08 0.92
108 INT100142 Negative_regulation of Localization of PTGS1 2 0.35 1.71 0.91
109 INT69553 Negative_regulation of Regulation of PTGS1 1 0.16 0.78 0.91
110 INT93406 Positive_regulation of Regulation of Ptgs1 2 0.14 0 0.9
111 INT80142 Positive_regulation of Localization of PTGS1 4 0.21 1.52 0.87
112 INT24372 Negative_regulation of Sphk1 1 0.59 0 0.85
113 INT149624 Regulation of Transcription of Ptgs2 1 0.16 0.84 0.84
114 INT115770 Negative_regulation of Positive_regulation of Ptgs2 4 0.43 0.94 0.79
115 INT120057 Regulation of Localization of PTGS2 1 0.28 0.14 0.78
116 INT71950 Positive_regulation of Binding of PTGS2 2 0.31 0.31 0.74
117 INT78957 Regulation of Transcription of Ptgs2 1 0.17 0.49 0.72
118 INT82544 Regulation of Positive_regulation of PTGS2 4 0.39 1.41 0.71
119 INT127175 Negative_regulation of Transcription of Ptgs2 3 0.47 2.11 0.7
120 INT24373 Gene_expression of Sphk1 3 0.67 0 0.68
121 INT93854 Positive_regulation of Transcription of Ptgs1 3 0.19 0.54 0.66
122 INT92341 Localization of Ptgs2 5 0.75 2.04 0.64
123 INT23612 Regulation of Negative_regulation of Ptgs1 3 0.19 0.69 0.64
124 INT108319 Regulation of Positive_regulation of Ptgs1 1 0.16 0.08 0.57
125 INT115772 Positive_regulation of Localization of Ptgs2 1 0.46 0.5 0.55
126 INT124836 Positive_regulation of Binding of Ptgs1 1 0.10 0.25 0.55
127 INT115771 Positive_regulation of Positive_regulation of Ptgs2 1 0.46 0.5 0.54
128 INT87959 Phosphorylation of Ptgs1 3 0.63 0.37 0.51
129 INT142835 Regulation of Localization of Ptgs2 2 0.25 0.26 0.5
130 INT24375 Regulation of Sphk1 1 0.62 0 0.5
131 INT91220 Positive_regulation of Binding of Ptgs1 1 0.02 0.76 0.47
132 INT24371 Positive_regulation of Sphk1 2 0.41 2.37 0.46
133 INT39228 Regulation of Regulation of Ptgs1 2 0.39 0.38 0.45
134 INT94036 Negative_regulation of Transcription of Ptgs2 1 0.30 0.52 0.43
135 INT191930 Negative_regulation of Negative_regulation of Ptgs1 1 0.07 0.94 0.42
136 INT231345 Positive_regulation of Localization of Ptgs1 1 0.16 0.82 0.36
137 INT82545 Positive_regulation of Regulation of PTGS2 1 0.19 0.15 0.35
138 INT24374 Regulation of Gene_expression of Sphk1 1 0.45 0 0.31
139 INT141727 Regulation of Binding of Ptgs1 1 0.11 0.33 0.28
140 INT76218 Negative_regulation of Localization of Ptgs1 1 0.08 0.25 0.25
141 INT130782 Positive_regulation of Transcription of PTGS1 1 0.02 0.19 0.25
142 INT302791 Negative_regulation of Gene_expression of Sphk1 1 0.23 0.34 0.24
143 INT59081 Regulation of Transcription of PTGS1 1 0.11 0.16 0.21
144 INT17849 Negative_regulation of Binding of PTGS2 2 0.38 0.16 0.2
145 INT148274 Negative_regulation of Regulation of PTGS2 1 0.01 0.47 0.19
146 INT87715 Negative_regulation of Negative_regulation of Ptgs2 1 0.16 0.68 0.17
147 INT247598 Regulation of Binding of Ptgs2 1 0.10 1.69 0.16
148 INT62468 Protein_catabolism of PTGS1 2 0.18 0.14 0.15
149 INT185690 Regulation of Phosphorylation of PTGS1 1 0.10 0.07 0.15
150 INT287672 Positive_regulation of Positive_regulation of Sphk1 1 0.48 0.38 0.14
151 INT129433 Regulation of Binding of PTGS2 1 0.25 1.01 0.14
152 INT52697 Regulation of Positive_regulation of Ptgs2 2 0.27 0.34 0.13
153 INT158618 Binding of Sphk1 1 0.01 0 0.13
154 INT212801 Phosphorylation of Ptgs2 2 0.22 1.03 0.1
155 INT287665 Regulation of Negative_regulation of Sphk1 1 0.43 0.11 0.1
156 INT283729 Protein_catabolism of Ptgs2 1 0.01 0.09 0.08
157 INT76370 Regulation of Transcription of Ptgs1 2 0.32 0.17 0.04
158 INT17845 Negative_regulation of Binding of Ptgs2 1 0.09 0.08 0.04
159 INT115751 Regulation of Localization of Ptgs1 1 0.27 0.08 0.04
160 INT287663 Localization of Sphk1 1 0.72 0.84 0
161 INT121544 Positive_regulation of Regulation of Ptgs2 1 0.14 0.15 0
162 INT287668 Regulation of Sphk1 1 0.43 0.66 0
163 INT287664 Binding of Sphk1 1 0.36 0.97 0
164 INT165132 Negative_regulation of Localization of Ptgs1 1 0.42 1.15 0
165 INT287661 Regulation of Positive_regulation of Sphk1 1 0.43 0 0
166 INT96041 Positive_regulation of Localization of Ptgs2 1 0.17 0.07 0
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