GO:0019441

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Name tryptophan catabolic process to kynurenine
Categary Process
Go Slim No
Go Link GO:0019441
Unique Molecular Interactions 40
Total Molecular Interactions 49
Total Single Events 932
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tryptophan catabolic process to kynurenine. They are ordered first by their pain relevance and then by number of times they were reported for tryptophan catabolic process to kynurenine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT153923 Msr1 Positive_regulation of Gene_expression of Tdo2 1 0.00 0.89 1.28
2 INT220051 Fcgr4 Positive_regulation of Gene_expression of Ido1 1 0.01 1.24 0.55
3 INT334180 Tdo2 Negative_regulation of Tbpl1 1 0.10 0.16 0.45
4 INT104447 Ido1 Negative_regulation of Binding of Atp7b 1 0.00 0.68 0.43
5 INT220050 Ctla4 Positive_regulation of Ido1 1 0.31 1.45 0.38
6 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27
7 INT220053 Il10 Positive_regulation of Ido1 1 0.14 0.74 0.19
8 INT334182 Tdo2 Positive_regulation of Gene_expression of Ngf 1 0.07 0.08 0.16
9 INT323345 Ido1 Positive_regulation of Gene_expression of Tlr4 1 0.14 0.69 0.13
10 INT268083 Ido1 Negative_regulation of Tyrp1 1 0.22 0 0.13
11 INT268082 Ido1 Positive_regulation of Gpr35 1 0.04 0 0.13
12 INT170330 Regulation of Regulation of Gene_expression of Ido1 1 0.01 0.38 0.08
13 INT226906 Binding of Ido1 and Il6 1 0.07 0.67 0.08
14 INT268088 Tdo2 Positive_regulation of Gene_expression of Ido1 1 0.41 0.09 0.04
15 INT268086 Tdo2 Positive_regulation of Tnfrsf9 1 0.20 0.09 0.04
16 INT268085 Tdo2 Regulation of Gene_expression of Tyrp1 1 0.25 0.09 0.04
17 INT170328 Gene_expression of Ido1 Positive_regulation of Hmga2 1 0.01 0.13 0.04
18 INT268084 Tdo2 Positive_regulation of Tyrp1 1 0.26 0.09 0.04
19 INT170337 Gene_expression of Ido1 Positive_regulation of MRXS5 1 0.01 0.12 0.03
20 INT170326 Ido1 Positive_regulation of Cpox 1 0.07 0.12 0.03
21 INT170338 Gene_expression of Ido1 Positive_regulation of IGHD2-15 1 0.02 0.12 0.03
22 INT170327 Ido1 Positive_regulation of Gene_expression of Cpox 1 0.07 0.12 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for tryptophan catabolic process to kynurenine. They are ordered first by their pain relevance and then by number of times they were reported in tryptophan catabolic process to kynurenine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170308 Gene_expression of Ido1 159 0.75 69.51 15.98
2 INT170295 Positive_regulation of Ido1 40 0.67 28.89 7.61
3 INT248206 Gene_expression of Tdo2 15 0.78 9.17 7.16
4 INT39418 Negative_regulation of Tdo2 12 0.57 0.8 6.93
5 INT170315 Positive_regulation of Gene_expression of Ido1 50 0.67 25.39 6.06
6 INT11298 Gene_expression of Ido1 6 0.58 6.71 4.85
7 INT170311 Negative_regulation of Ido1 16 0.48 14.47 4.81
8 INT143557 Positive_regulation of Ido1 6 0.40 5.34 4.8
9 INT170323 Regulation of Gene_expression of Ido1 11 0.60 8.74 2.33
10 INT45396 Positive_regulation of Tdo2 6 0.61 0.92 2.1
11 INT90688 Negative_regulation of Tdo2 12 0.59 5.82 2.02
12 INT143561 Positive_regulation of Positive_regulation of Ido1 1 0.36 1.84 1.89
13 INT90687 Gene_expression of Tdo2 1 0.64 0.88 1.86
14 INT150248 Positive_regulation of Gene_expression of Ido1 2 0.43 2.68 1.77
15 INT186268 Positive_regulation of Tdo2 13 0.50 8 1.32
16 INT220046 Positive_regulation of Negative_regulation of Ido1 1 0.41 2.98 1.12
17 INT39419 Positive_regulation of Negative_regulation of Tdo2 3 0.43 0.19 1.09
18 INT88177 Negative_regulation of Ido1 3 0.25 0.51 1.02
19 INT220043 Positive_regulation of Positive_regulation of Ido1 2 0.41 1.94 0.83
20 INT143559 Positive_regulation of Protein_catabolism of Ido1 1 0.29 0.93 0.79
21 INT143560 Protein_catabolism of Ido1 1 0.52 0.93 0.79
22 INT143558 Negative_regulation of Negative_regulation of Ido1 1 0.25 0.49 0.76
23 INT90686 Regulation of Tdo2 1 0.43 0 0.59
24 INT90685 Regulation of Gene_expression of Tdo2 1 0.43 0 0.59
25 INT69369 Binding of Tdo2 4 0.33 0.07 0.51
26 INT170299 Negative_regulation of Gene_expression of Ido1 12 0.57 2.59 0.5
27 INT132472 Positive_regulation of Positive_regulation of Tdo2 1 0.39 0.32 0.48
28 INT220048 Protein_catabolism of Ido1 1 0.81 1.03 0.47
29 INT270034 Negative_regulation of Positive_regulation of Ido1 1 0.19 2.23 0.42
30 INT268066 Regulation of Tdo2 5 0.32 3.13 0.41
31 INT270027 Regulation of Positive_regulation of Ido1 1 0.23 1.17 0.39
32 INT170318 Regulation of Ido1 6 0.38 2.63 0.38
33 INT334163 Localization of Tdo2 1 0.65 0.55 0.32
34 INT334166 Regulation of Localization of Tdo2 1 0.39 0.56 0.32
35 INT69368 Positive_regulation of Binding of Tdo2 2 0.44 0 0.28
36 INT268074 Positive_regulation of Positive_regulation of Tdo2 2 0.41 0.74 0.22
37 INT11299 Binding of Ido1 1 0.31 0.15 0.15
38 INT268080 Transcription of Tdo2 3 0.72 1.41 0.14
39 INT46441 Positive_regulation of Localization of Tdo2 1 0.02 0.26 0.14
40 INT46442 Localization of Tdo2 1 0.02 0.26 0.14
41 INT268081 Positive_regulation of Gene_expression of Tdo2 3 0.61 0.07 0.13
42 INT268077 Positive_regulation of Negative_regulation of Tdo2 2 0.44 0.61 0.13
43 INT170320 Binding of Ido1 1 0.36 0.19 0.11
44 INT170297 Positive_regulation of Regulation of Ido1 1 0.39 0.29 0.1
45 INT339608 Localization of Ido1 1 0.14 0.41 0.08
46 INT268075 Negative_regulation of Transcription of Tdo2 1 0.59 1.42 0.06
47 INT334168 Negative_regulation of Regulation of Tdo2 1 0.38 0 0.04
48 INT268068 Negative_regulation of Gene_expression of Tdo2 1 0.51 0.08 0.03
49 INT268072 Negative_regulation of Positive_regulation of Tdo2 1 0.43 0.08 0.03
50 INT150246 Negative_regulation of Gene_expression of Ido1 1 0.07 0 0
51 INT334164 Regulation of Transcription of Tdo2 1 0.39 0 0
52 INT109754 Phosphorylation of Tdo2 1 0.62 0 0
53 INT170301 Negative_regulation of Negative_regulation of Ido1 1 0.36 0.32 0
54 INT170310 Transcription of Ido1 1 0.61 0.52 0
55 INT150247 Transcription of Ido1 1 0.10 0 0
56 INT109755 Binding of Tdo2 1 0.48 0 0
57 INT150249 Negative_regulation of Transcription of Ido1 1 0.08 0 0
58 INT109756 Negative_regulation of Binding of Tdo2 1 0.43 0 0
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