GO:0019534

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Name toxin transporter activity
Categary Function
Go Slim No
Go Link GO:0019534
Unique Molecular Interactions 17
Total Molecular Interactions 26
Total Single Events 113
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for toxin transporter activity. They are ordered first by their pain relevance and then by number of times they were reported for toxin transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67
2 INT111837 Binding of ABCB1 and SLC22A3 1 0.35 0 0.31
3 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19
4 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12
5 INT262187 Nr1i2 Positive_regulation of Gene_expression of Abcg1 1 0.24 0.21 0.06
6 INT239333 Abcg1 Positive_regulation of RCT 1 0.06 1.29 0.03
7 INT167565 Binding of ERG and LRP5 1 0.02 0.94 0.03
8 INT307602 Binding of ACHE and LRP5 1 0.01 0.17 0
9 INT302321 Negative_regulation of Binding of Lrp6 and SOST 1 0.16 0.26 0
10 INT302320 Binding of Lrp6 and SOST 1 0.18 0.26 0
11 INT335887 Akt1 Regulation of Lrp6 1 0.06 0.15 0
12 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0
13 INT344711 Nr1h3 Regulation of Abcg1 1 0.03 1.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for toxin transporter activity. They are ordered first by their pain relevance and then by number of times they were reported in toxin transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT40368 Positive_regulation of LRP5 5 0.49 3.19 3.51
2 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
3 INT111838 Regulation of SLC22A3 1 0.38 0 0.94
4 INT72334 Negative_regulation of LRP5 7 0.35 1.71 0.81
5 INT40369 Gene_expression of LRP5 8 0.55 5.63 0.74
6 INT117369 Gene_expression of SLC22A3 3 0.59 0.22 0.7
7 INT231558 Regulation of LRP5 2 0.24 1.02 0.68
8 INT109468 Negative_regulation of SLC22A3 1 0.13 0.15 0.66
9 INT40367 Positive_regulation of Gene_expression of LRP5 1 0.09 0 0.57
10 INT239289 Gene_expression of Abcg1 3 0.31 2.27 0.5
11 INT344684 Positive_regulation of Gene_expression of Abcg1 1 0.10 0.95 0.38
12 INT335875 Regulation of Lrp6 1 0.57 0.43 0.27
13 INT334543 Negative_regulation of Positive_regulation of LRP5 1 0.23 1.81 0.25
14 INT173655 Binding of LRP5 10 0.39 3.06 0.22
15 INT335861 Localization of Lrp6 1 0.69 0.54 0.17
16 INT239307 Positive_regulation of Abcg1 1 0.24 0.73 0.17
17 INT131262 Transcription of SLC22A3 1 0.03 0 0.16
18 INT131267 Positive_regulation of Gene_expression of SLC22A3 1 0.02 0 0.16
19 INT187880 Binding of Abcg1 3 0.33 2.07 0.1
20 INT229152 Negative_regulation of Abcg1 2 0.19 1.35 0.08
21 INT335865 Positive_regulation of Phosphorylation of Lrp6 1 0.64 0.46 0.05
22 INT335862 Phosphorylation of Lrp6 1 0.76 0.37 0.05
23 INT242172 Protein_catabolism of LRP5 1 0.64 0.06 0.04
24 INT239270 Transcription of Abcg1 1 0.27 1.21 0.03
25 INT307613 Phosphorylation of LRP5 1 0.08 0.1 0
26 INT173644 Negative_regulation of Gene_expression of LRP5 1 0.15 0.59 0
27 INT335872 Positive_regulation of Gene_expression of Lrp6 1 0.46 0.18 0
28 INT302465 Localization of LRP5 1 0.61 0 0
29 INT223292 Localization of SLC22A3 1 0.29 0.06 0
30 INT347117 Negative_regulation of Binding of Lrp6 1 0.28 0.5 0
31 INT335866 Regulation of Transcription of Lrp6 1 0.42 0.25 0
32 INT307611 Positive_regulation of Phosphorylation of LRP5 1 0.05 0.1 0
33 INT335881 Gene_expression of Lrp6 1 0.62 0.09 0
34 INT335873 Transcription of Lrp6 1 0.64 0.25 0
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