GO:0019538

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Name protein metabolic process
Categary Process
Go Slim No
Go Link GO:0019538
Unique Molecular Interactions 48
Total Molecular Interactions 60
Total Single Events 703
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for protein metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT227543 Mtx1 Positive_regulation of Prep 1 0.22 1.19 1.92
2 INT227542 Mtx1 Positive_regulation of Binding of Prep 1 0.23 1.2 1.92
3 INT101443 Penk Positive_regulation of Localization of Gcg 1 0.50 1.21 1.04
4 INT227545 Hspa9 Positive_regulation of Prep 1 0.18 0.59 0.96
5 INT101676 Sst Negative_regulation of Localization of Gcg 1 0.03 0 0.72
6 INT101444 Penk Regulation of Localization of Gcg 1 0.45 0.77 0.71
7 INT227544 Hspa9 Regulation of Gene_expression of Prep 1 0.15 0.57 0.61
8 INT7849 Man2a2 Positive_regulation of Localization of Gcg 1 0.08 0 0.51
9 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43
10 INT7850 Adra2c Regulation of Localization of Gcg 1 0.08 0 0.27
11 INT37309 Ins1 Negative_regulation of Localization of Gcg 1 0.12 0 0.27
12 INT29257 Pomc Positive_regulation of Gcg 1 0.17 0.23 0.21
13 INT316482 Il6 Positive_regulation of Cdh1 1 0.03 0.33 0.15
14 INT1233 Gcg Positive_regulation of Pdpk1 1 0.27 0 0.14
15 INT321983 Glp1r Negative_regulation of Localization of Gcg 1 0.09 1.36 0.11
16 INT43284 Binding of Npr1 and Gcg 1 0.05 0 0.1
17 INT52894 Gcg Negative_regulation of Ins1 1 0.16 0.18 0.09
18 INT275771 Binding of Prep and Musd1 1 0.00 0 0.08
19 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
20 INT349916 Binding of Ctnnd1 and Cdh1 1 0.17 0.47 0.07
21 INT46528 Binding of Ins1 and Gcg 1 0.25 0.07 0.06
22 INT46529 Gcg Positive_regulation of Ins1 1 0.34 0.07 0.06
23 INT43283 Gcg Positive_regulation of Npr1 1 0.07 0 0.05
24 INT251373 Binding of Cdh2 and Cdh1 1 0.17 0 0.04
25 INT342726 Binding of Laptm5 and Park2 1 0.03 0.64 0.04
26 INT317301 Binding of Park2 and Park7 1 0.36 0.62 0
27 INT342725 Pink1 Positive_regulation of Phosphorylation of Park2 1 0.29 0.62 0
28 INT306638 Prep Positive_regulation of Positive_regulation of Nfatc4 1 0.09 0.16 0
29 INT251370 Cdh2 Regulation of Gene_expression of Cdh1 1 0.21 0.35 0
30 INT306636 Prep Positive_regulation of Nfatc4 1 0.11 0.28 0
31 INT306623 Prep Regulation of Gene_expression of Mstn 1 0.14 0.28 0
32 INT317300 Binding of Park2 and Pink1 1 0.48 1.23 0
33 INT342727 Pink1 Positive_regulation of Park2 1 0.29 0.62 0
34 INT312318 Binding of Cdh1 and Regulation of Transcription of Prl 1 0.30 0.39 0
35 INT310042 Binding of Cdh1 and Lsr1 1 0.01 0.09 0
36 INT306631 Binding of Mstn and Prep 1 0.13 0.19 0
37 INT306624 Prep Positive_regulation of Akt1 1 0.08 0.28 0
38 INT317302 Binding of Park2 and Mul1 1 0.01 0.62 0
39 INT239184 Msr1 Negative_regulation of Msra 1 0.21 0.13 0
40 INT312316 Gene_expression of Cdh1 Negative_regulation of Prl 1 0.29 0 0
41 INT321976 Dpp4 Regulation of Gcg 1 0.13 1.06 0
42 INT306643 Prep Positive_regulation of Gene_expression of Mstn 1 0.12 0.39 0
43 INT306637 Prep Positive_regulation of Positive_regulation of Mstn 1 0.12 0.62 0
44 INT251372 Cdh1 Regulation of Gene_expression of Cdh2 1 0.21 0.35 0
45 INT310039 Binding of Cdh1 and Slc30a4 1 0.04 0.46 0
46 INT321977 Dpp4 Regulation of Negative_regulation of Gcg 1 0.13 1.06 0
47 INT235009 Binding of DSG1 and Cdh1 1 0.02 0.87 0
48 INT312317 Cdh1 Regulation of Transcription of Prl 1 0.41 0.39 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in protein metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1473 Localization of Gcg 95 0.80 17.35 30.31
2 INT6575 Positive_regulation of Localization of Gcg 33 0.69 3.48 13.31
3 INT2586 Positive_regulation of Gcg 35 0.70 9.25 11.75
4 INT3658 Regulation of Gcg 28 0.53 12.89 8.58
5 INT2587 Regulation of Localization of Gcg 22 0.60 1.73 7.59
6 INT3659 Negative_regulation of Gcg 26 0.51 10.08 7.39
7 INT168446 Gene_expression of Prep 25 0.64 15.17 5.94
8 INT3894 Negative_regulation of Localization of Gcg 18 0.52 2.7 5.77
9 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56
10 INT81761 Negative_regulation of Prep 12 0.55 8.48 4.73
11 INT1634 Gene_expression of Gcg 25 0.75 14.98 4.42
12 INT61341 Positive_regulation of Prep 12 0.63 6.08 3.37
13 INT227524 Positive_regulation of Gene_expression of Prep 13 0.48 7.69 3.28
14 INT61340 Regulation of Prep 7 0.50 6.13 2.31
15 INT43282 Binding of Gcg 5 0.32 0.61 2.18
16 INT56705 Negative_regulation of Positive_regulation of Gcg 1 0.51 0 2.17
17 INT169705 Negative_regulation of Gene_expression of Cdh1 10 0.57 8.8 2.1
18 INT227424 Binding of Prep 6 0.35 2.61 1.39
19 INT122103 Negative_regulation of Cdh1 5 0.49 2.05 1.18
20 INT169704 Regulation of Gene_expression of Cdh1 4 0.35 1.75 1.09
21 INT10264 Regulation of Regulation of Gcg 2 0.39 0 1.05
22 INT276620 Negative_regulation of Cdh1 7 0.57 6.48 0.86
23 INT235069 Localization of Cdh1 9 0.74 3.81 0.71
24 INT87717 Negative_regulation of Regulation of Gcg 1 0.02 0 0.67
25 INT189877 Gene_expression of Cdh1 55 0.58 9.36 0.66
26 INT59380 Transcription of Prep 3 0.56 1.2 0.66
27 INT105959 Positive_regulation of Gene_expression of Cdh1 5 0.49 2.65 0.57
28 INT18168 Protein_catabolism of Gcg 4 0.99 1.17 0.56
29 INT83550 Negative_regulation of Gene_expression of Gcg 2 0.42 1.52 0.52
30 INT301995 Regulation of Cdh1 5 0.44 3.8 0.48
31 INT43909 Positive_regulation of Gene_expression of Gcg 3 0.48 1.45 0.45
32 INT172558 Positive_regulation of Cdh1 11 0.49 8.92 0.42
33 INT43910 Regulation of Gene_expression of Gcg 3 0.27 3.71 0.41
34 INT227517 Regulation of Negative_regulation of Prep 1 0.42 0 0.33
35 INT113894 Positive_regulation of Protein_catabolism of Gcg 1 0.25 0.32 0.32
36 INT50750 Transcription of Gcg 1 0.53 0.85 0.25
37 INT234858 Binding of Cdh1 11 0.47 4.58 0.22
38 INT215000 Transcription of Cdh1 4 0.40 1.17 0.22
39 INT115003 Binding of Msra 2 0.28 0.47 0.19
40 INT3895 Positive_regulation of Positive_regulation of Gcg 2 0.49 0.8 0.18
41 INT275767 Localization of Prep 1 0.15 0 0.17
42 INT211098 Negative_regulation of Msra 1 0.01 1.36 0.16
43 INT305227 Negative_regulation of Gene_expression of Prep 2 0.11 1.42 0.1
44 INT296622 Positive_regulation of Gene_expression of Cdh1 3 0.52 2.24 0.09
45 INT296623 Positive_regulation of Cdh1 2 0.35 1.88 0.09
46 INT3893 Positive_regulation of Regulation of Gcg 1 0.46 0.8 0.09
47 INT276619 Negative_regulation of Transcription of Cdh1 1 0.24 0.57 0.09
48 INT342696 Gene_expression of Park2 1 0.65 1.19 0.08
49 INT251364 Negative_regulation of Gene_expression of Cdh1 4 0.32 1.02 0.07
50 INT21668 Regulation of Positive_regulation of Gcg 1 0.34 0.58 0.06
51 INT227516 Regulation of Transcription of Prep 1 0.37 0 0.06
52 INT349912 Negative_regulation of Negative_regulation of Cdh1 1 0.42 1.04 0.05
53 INT189881 Binding of Cdh1 6 0.36 1.24 0.04
54 INT196396 Positive_regulation of Msra 2 0.36 1.09 0.04
55 INT317299 Binding of Park2 1 0.36 0.61 0.04
56 INT251361 Transcription of Cdh1 1 0.36 0 0.04
57 INT349906 Negative_regulation of Localization of Cdh1 1 0.42 0.37 0.04
58 INT291466 Phosphorylation of Gcg 1 0.15 0.73 0.03
59 INT251359 Regulation of Cdh1 2 0.34 0.47 0
60 INT189878 Localization of Cdh1 2 0.56 0.34 0
61 INT251362 Regulation of Gene_expression of Cdh1 2 0.46 0.4 0
62 INT342695 Phosphorylation of Park2 1 0.79 0.62 0
63 INT189879 Positive_regulation of Binding of Cdh1 1 0.08 0.15 0
64 INT301987 Negative_regulation of Positive_regulation of Cdh1 1 0.07 1.28 0
65 INT312313 Protein_catabolism of Cdh1 1 0.75 0.21 0
66 INT325678 Negative_regulation of Protein_catabolism of Gcg 1 0.02 0.8 0
67 INT349911 Regulation of Negative_regulation of Cdh1 1 0.44 0.23 0
68 INT324055 Regulation of Transcription of Cdh1 1 0.09 0.49 0
69 INT189883 Negative_regulation of Localization of Cdh1 1 0.07 0.06 0
70 INT296611 Positive_regulation of Negative_regulation of Cdh1 1 0.11 0.78 0
71 INT310014 Phosphorylation of Cdh1 1 0.16 0.24 0
72 INT306602 Negative_regulation of Negative_regulation of Prep 1 0.10 1.09 0
73 INT239156 Gene_expression of Msra 1 0.47 0 0
74 INT301989 Positive_regulation of Binding of Cdh1 1 0.08 0.42 0
75 INT349904 Regulation of Localization of Cdh1 1 0.44 0.05 0
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