GO:0019825

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Name oxygen binding
Categary Function
Go Slim No
Go Link GO:0019825
Unique Molecular Interactions 391
Total Molecular Interactions 534
Total Single Events 10366
Pain Genes Associated 32

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for oxygen binding. They are ordered first by their pain relevance and then by number of times they were reported for oxygen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
2 INT66157 Binding of ALB and BDP1 1 0.11 0 2.13
3 INT168010 Asap1 Positive_regulation of HBG2 1 0.01 3.03 1.82
4 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61
5 INT100784 RYBP Positive_regulation of CYP3A4 1 0.44 0 1.54
6 INT40887 Penk Regulation of Th 1 0.04 0 1.53
7 INT123899 Binding of CYP3A4 and UGT2B7 1 0.52 0 1.46
8 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 0.13 0.15 1.36
9 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
10 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32
11 INT153923 Msr1 Positive_regulation of Gene_expression of Tdo2 1 0.00 0.89 1.28
12 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
13 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
14 INT90644 Slc6a3 Positive_regulation of Th 1 0.51 0 1.2
15 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
16 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
17 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
18 INT19535 Binding of ADRA1D and ALB 3 0.42 0.8 1.15
19 INT106069 TH Positive_regulation of Th 1 0.07 0.16 1.14
20 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1
21 INT264988 Binding of CYP2C19 and CYP3A4 1 0.18 0.72 1.09
22 INT44838 Pitpnm1 Negative_regulation of Th 1 0.02 0 1.09
23 INT31547 Binding of Th and Vip 1 0.31 0 1.08
24 INT28186 CYP2E1 Regulation of Positive_regulation of RYBP 1 0.04 0.33 1.08
25 INT264987 Binding of CYP2C9 and CYP3A4 1 0.19 0.71 1.08
26 INT221 Chd7 Negative_regulation of Th 1 0.02 0 1.04
27 INT41175 Adra2a Regulation of Th 1 0.59 0 1.04
28 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 0.30 0.38 0.99
29 INT31548 Binding of Th and Dbh 1 0.35 0 0.98
30 INT73680 KNG1 Positive_regulation of ALB 1 0.51 0.38 0.98
31 INT52806 CYP2E1 Positive_regulation of RYBP 1 0.43 0.24 0.95
32 INT168026 Positive_regulation of HBG2 Regulation of Gpt 1 0.01 0.15 0.89
33 INT168025 HBG2 Regulation of Gpt 1 0.01 0.15 0.88
34 INT354522 Binding of HBG2 and Wipi1 1 0.00 2.64 0.87
35 INT184916 Binding of da and Th 1 0.09 1.22 0.87
36 INT122687 Binding of Galr2 and Th 1 0.13 0.07 0.83
37 INT122688 Binding of Galr1 and Th 1 0.14 0.07 0.83
38 INT122686 Binding of Galr3 and Th 1 0.14 0.07 0.83
39 INT63940 Negative_regulation of Vta1 Positive_regulation of Th 1 0.13 0 0.81
40 INT218037 Binding of ALB and Penk 1 0.13 0 0.81
41 INT110726 Binding of ALB and LTF 1 0.01 0 0.81
42 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77
43 INT184918 da Positive_regulation of Negative_regulation of Th 1 0.14 0.14 0.77
44 INT139893 Binding of Alb and Alms1 1 0.04 0.48 0.75
45 INT147278 Negative_regulation of Calca Positive_regulation of Th 1 0.41 0.76 0.74
46 INT147277 Calca Positive_regulation of Th 1 0.48 0.76 0.74
47 INT144367 Gdnf Negative_regulation of Positive_regulation of Th 1 0.11 0.77 0.7
48 INT313435 Syp Regulation of Th 1 0.43 1.6 0.64
49 INT92045 Binding of ALB and SERPINA1 1 0.30 1.37 0.64
50 INT7958 LOC686180 Positive_regulation of Gene_expression of Th 1 0.02 0 0.64
51 INT315334 Binding of CYP3A4 and CDIPT 3 0.04 0.85 0.59
52 INT126150 CYGB Regulation of CDNF 1 0.00 0.28 0.57
53 INT50883 Binding of AGTR2 and ALB 1 0.37 0.19 0.56
54 INT544 Binding of ALB and GC 1 0.13 0 0.55
55 INT114029 Binding of ALB and Mmp3 1 0.01 0.31 0.55
56 INT351581 Binding of ALB and GOPC 1 0.11 0 0.55
57 INT220051 Fcgr4 Positive_regulation of Gene_expression of Ido1 1 0.01 1.24 0.55
58 INT114028 Negative_regulation of Binding of ALB and Mmp3 1 0.01 0.31 0.55
59 INT23485 HBE1 Positive_regulation of Localization of PLOD1 1 0.04 0 0.54
60 INT23486 HBE1 Positive_regulation of Localization of FSHB 1 0.03 0 0.54
61 INT23482 HBE1 Positive_regulation of PLOD1 1 0.04 0 0.53
62 INT228852 Th Positive_regulation of Vta1 1 0.04 0 0.53
63 INT23484 Positive_regulation of HBE1 Positive_regulation of PLOD1 1 0.04 0 0.53
64 INT23483 HBE1 Positive_regulation of FSHB 1 0.01 0 0.53
65 INT228851 Th Positive_regulation of Mtf2 1 0.02 0 0.52
66 INT184922 Negative_regulation of Th Negative_regulation of da 1 0.12 0.18 0.52
67 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
68 INT64514 Binding of TNNI3 and Mb 2 0.03 1.64 0.5
69 INT27730 Binding of ALB and Shbg 2 0.01 0.44 0.5
70 INT210878 Binding of FLT1 and HBM 1 0.06 0.83 0.5
71 INT7957 Calca Positive_regulation of Gene_expression of Th 1 0.39 0 0.47
72 INT17774 Alb Negative_regulation of Dnase1 1 0.02 0 0.46
73 INT334180 Tdo2 Negative_regulation of Tbpl1 1 0.10 0.16 0.45
74 INT123897 Binding of CYP3A4 and SLC35A2 1 0.39 0 0.45
75 INT249021 Gabrg1 Negative_regulation of Th 1 0.08 0.06 0.44
76 INT104447 Ido1 Negative_regulation of Binding of Atp7b 1 0.00 0.68 0.43
77 INT126149 CYGB Positive_regulation of CEBPZ 1 0.03 0.26 0.43
78 INT126152 CYGB Positive_regulation of CDNF 1 0.00 0.26 0.43
79 INT121837 Sct Positive_regulation of Th 1 0.23 0.06 0.43
80 INT139487 Oprm1 Positive_regulation of Th 1 0.26 0.1 0.42
81 INT110727 Binding of HBM and LTF 1 0.00 0 0.41
82 INT98214 Negative_regulation of Binding of TNNI3 and Mb 1 0.02 0.91 0.41
83 INT147280 Binding of Pecam1 and Th 1 0.29 0.41 0.41
84 INT123898 CYP3A4 Regulation of UGT2B7 1 0.22 0 0.41
85 INT46225 Binding of ALB and POMC 1 0.36 0 0.4
86 INT302871 Negative_regulation of Adora2a Positive_regulation of Phosphorylation of Th 1 0.26 0.12 0.4
87 INT7625 Man2a2 Regulation of Th 1 0.01 0.07 0.4
88 INT31794 Hps6 Positive_regulation of Th 1 0.03 0 0.38
89 INT220050 Ctla4 Positive_regulation of Ido1 1 0.31 1.45 0.38
90 INT43956 GCG Regulation of ALB 1 0.16 0.15 0.38
91 INT69467 CYP2E1 Positive_regulation of Localization of CYP3A 1 0.30 0 0.36
92 INT69469 CYP2E1 Positive_regulation of CYP2B6 1 0.36 0 0.36
93 INT187064 ARSD Negative_regulation of CYP19A1 1 0.22 0.7 0.35
94 INT134427 Alb Regulation of GGT1 1 0.05 0.7 0.35
95 INT173476 Th Regulation of Gene_expression of Bcar1 1 0.10 0 0.34
96 INT34855 Negative_regulation of Maoa Negative_regulation of Th 1 0.17 0 0.34
97 INT173478 Th Regulation of Localization of Ins1 1 0.13 0 0.34
98 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
99 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.97 0.32
100 INT153019 nct Positive_regulation of Transcription of Th 1 0.19 0.61 0.32
101 INT153020 nct Positive_regulation of Gene_expression of Th 1 0.19 0.61 0.32
102 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31
103 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
104 INT290614 Binding of Th and RLS 1 0.21 3.26 0.31
105 INT35963 Binding of ALB and MPG 1 0.40 0 0.3
106 INT90643 Negative_regulation of Slc6a3 Positive_regulation of Th 1 0.47 0 0.3
107 INT55404 Binding of ENG and Th 1 0.02 0 0.3
108 INT132984 CYP3A4 Positive_regulation of Gene_expression of PPP4C 1 0.44 0 0.3
109 INT181294 HBM Positive_regulation of NGB 1 0.02 0.74 0.3
110 INT181295 MB Positive_regulation of NGB 1 0.10 0.73 0.3
111 INT314484 TH Positive_regulation of RLS 1 0.01 1.66 0.29
112 INT134927 CYP19A1 Positive_regulation of Gene_expression of MME 1 0.30 1.04 0.28
113 INT126006 Binding of ALB and IL8 1 0.41 0.28 0.28
114 INT134930 MME Positive_regulation of Gene_expression of CYP19A1 1 0.30 1.04 0.28
115 INT78484 Binding of DBH and TH 1 0.09 0 0.28
116 INT351391 Binding of Sod2 and Gtf3a 1 0.00 0.18 0.27
117 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27
118 INT262329 TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26
119 INT262330 Positive_regulation of TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26
120 INT262227 Nr1h4 Regulation of Transcription of CYP3A4 1 0.08 0.12 0.26
121 INT162502 NEUROD1 Regulation of CYP1A1 2 0.07 0.09 0.25
122 INT272997 Binding of CYP3A4 and IL33 1 0.03 0 0.25
123 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
124 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
125 INT262229 Binding of CYP3A4 and Casr 1 0.03 0.37 0.24
126 INT111664 Binding of CPN1 and Alb 1 0.00 0.98 0.24
127 INT329432 Binding of CCR6 and TH 1 0.00 0.47 0.23
128 INT329431 Binding of CCL20 and TH 1 0.00 0.47 0.23
129 INT354926 IL6 Regulation of Gene_expression of ALB 1 0.14 1.3 0.23
130 INT118840 VEGFA Regulation of Positive_regulation of Mb 1 0.05 0.36 0.23
131 INT354924 IL6 Positive_regulation of Gene_expression of ALB 1 0.26 1.3 0.23
132 INT115729 Binding of CYP3A7 and CYP3A4 1 0.44 0.05 0.23
133 INT89612 Binding of FABP3 and MB 3 0.34 1.49 0.22
134 INT351318 Binding of CYP2C19 and Cyp1a2 1 0.01 0.28 0.22
135 INT118838 Gene_expression of Vegfa Positive_regulation of Gene_expression of Mb 1 0.44 0.4 0.22
136 INT91686 Mb Positive_regulation of Edn1 1 0.03 0.29 0.22
137 INT148533 Binding of Alb and Fas 1 0.23 0.08 0.21
138 INT318039 CDIPT Positive_regulation of CYP3A4 1 0.06 0.06 0.2
139 INT64964 Binding of Alb and Cd24 1 0.02 0.2 0.2
140 INT64967 Binding of AGFG1 and Alb 1 0.01 0.2 0.2
141 INT145140 Negative_regulation of CPOX Negative_regulation of Gene_expression of CYP19A1 1 0.13 0.47 0.2
142 INT262224 Sfn Negative_regulation of Transcription of CYP3A4 1 0.06 0.58 0.2
143 INT61987 Th Regulation of Penk 1 0.46 0 0.2
144 INT199191 Negative_regulation of Sod2 Positive_regulation of Ros1 1 0.08 0 0.19
145 INT161746 Binding of G6PD and HBG2 1 0.21 0.36 0.19
146 INT220053 Il10 Positive_regulation of Ido1 1 0.14 0.74 0.19
147 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19
148 INT349504 Ptpn2 Negative_regulation of Th 1 0.23 2 0.19
149 INT130740 Regulation of Binding of Tnnt2 and Mb 1 0.00 0.47 0.19
150 INT130741 Binding of Tnnt2 and Mb 1 0.01 0.47 0.19
151 INT330986 CYP2C9 Positive_regulation of Gene_expression of CYP3A4 1 0.39 0 0.18
152 INT57612 Binding of ALB and HGF 1 0.20 0.52 0.18
153 INT126007 Negative_regulation of Binding of ALB and IL8 1 0.37 0.18 0.18
154 INT330985 CYP2C9 Positive_regulation of Gene_expression of CYP2C19 1 0.34 0 0.18
155 INT151895 Binding of CYP3A4 and GBE1 1 0.01 0.24 0.18
156 INT319173 TXN Positive_regulation of Gene_expression of SOD2 1 0.23 0.1 0.18
157 INT313453 Siglec1 Regulation of Th 1 0.02 0.61 0.17
158 INT161148 ALB Regulation of Gene_expression of COMMD3 1 0.08 0 0.17
159 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
160 INT88450 Uncx Regulation of Gene_expression of Th 1 0.06 0 0.17
161 INT161143 MPG Regulation of ALB 1 0.16 0 0.17
162 INT161145 ORM2 Regulation of ALB 1 0.06 0 0.17
163 INT161149 ALB Regulation of OXA1L 1 0.15 0 0.17
164 INT85828 CYP3A4 Negative_regulation of CYP2D6 1 0.47 0.06 0.16
165 INT334182 Tdo2 Positive_regulation of Gene_expression of Ngf 1 0.07 0.08 0.16
166 INT151894 NR1I2 Positive_regulation of CYP3A4 1 0.19 0.23 0.16
167 INT349503 Ptpn2 Negative_regulation of Gene_expression of Th 1 0.23 0.7 0.16
168 INT65883 Binding of CYP1A1 and PPP4C 1 0.02 0 0.15
169 INT273561 Binding of CYP1A1 and CYP3A4 1 0.02 0.12 0.15
170 INT60364 GRP Positive_regulation of Localization of ALB 1 0.02 0.15 0.15
171 INT286901 Binding of HBM and VEGFA 1 0.05 1.08 0.14
172 INT262231 Sfn Negative_regulation of Gene_expression of CYP3A4 1 0.06 0.26 0.14
173 INT286900 Binding of HBM and PDGFA 1 0.04 1.08 0.14
174 INT262232 Nr1i2 Positive_regulation of Gene_expression of CYP3A4 1 0.17 0.26 0.14
175 INT286898 Binding of HBM and IL6 1 0.01 1.09 0.14
176 INT256320 Binding of CYP26A1 and Hapln1 1 0.01 1.27 0.14
177 INT343027 Binding of CYP3A4 and Azi1 1 0.02 0.75 0.14
178 INT323345 Ido1 Positive_regulation of Gene_expression of Tlr4 1 0.14 0.69 0.13
179 INT261456 Sftpd Positive_regulation of Gene_expression of Th 1 0.10 0.77 0.13
180 INT268083 Ido1 Negative_regulation of Tyrp1 1 0.22 0 0.13
181 INT313441 Th Regulation of Siglec1 1 0.02 0.22 0.13
182 INT262228 Nr1i2 Positive_regulation of Transcription of CYP3A4 1 0.17 0.27 0.13
183 INT268082 Ido1 Positive_regulation of Gpr35 1 0.04 0 0.13
184 INT313439 Syp Negative_regulation of Th 1 0.30 0.14 0.13
185 INT197317 Nr4a2 Regulation of Gene_expression of Th 1 0.03 0.07 0.12
186 INT262226 Positive_regulation of Nr1i2 Positive_regulation of CYP3A4 1 0.17 0.68 0.12
187 INT177589 Binding of HBG1 and C7orf49 1 0.00 0 0.12
188 INT97081 CYP3A4 Regulation of HAGH 1 0.02 0 0.11
189 INT188202 HBE1 Positive_regulation of MAPK1 1 0.01 0.14 0.11
190 INT71755 Nppa Regulation of Localization of Alb 1 0.25 1.29 0.11
191 INT37489 Binding of ADRA1D and Alb 1 0.34 0.84 0.11
192 INT188192 HBE1 Positive_regulation of LY6E 1 0.00 0.14 0.11
193 INT97080 CYP2E1 Regulation of HAGH 1 0.02 0 0.11
194 INT266900 Gene_expression of Sod2 Negative_regulation of Gene_expression of Sod1 1 0.11 0.41 0.11
195 INT210363 Binding of ALB and M6PR 1 0.00 1.19 0.1
196 INT173126 CYP8B1 Positive_regulation of PPARA 1 0.25 0.39 0.1
197 INT302883 Binding of TXN and Alb 1 0.06 4.13 0.1
198 INT313454 Negative_regulation of Syp Negative_regulation of Th 1 0.30 0.14 0.1
199 INT186242 Binding of ALB and SCN5A 1 0.04 0.36 0.1
200 INT155221 Binding of CYP3A4 and PNPLA4 1 0.09 0 0.1

Single Events

The table below shows the top 100 pain related interactions that have been reported for oxygen binding. They are ordered first by their pain relevance and then by number of times they were reported in oxygen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
2 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
3 INT7327 Regulation of Th 164 0.62 29.67 110.14
4 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
5 INT546 Binding of ALB 311 0.48 85.98 60.14
6 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51
7 INT613 Gene_expression of Alb 268 0.78 149.84 42.78
8 INT350 Localization of Th 79 0.80 10.26 41.17
9 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75
10 INT30817 Gene_expression of Th 142 0.76 33.56 38.12
11 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45
12 INT7326 Transcription of Th 83 0.72 13.5 35.33
13 INT234 Binding of Alb 151 0.48 52.34 32.97
14 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
15 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65
16 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
17 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27
18 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6
19 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79
20 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7
21 INT4781 Gene_expression of TH 68 0.73 26.92 24.01
22 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78
23 INT7678 Localization of Alb 142 0.81 80.93 22.49
24 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21
25 INT13643 Phosphorylation of Th 20 0.82 1.9 20.97
26 INT24240 Positive_regulation of Th 60 0.70 9.92 20.18
27 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35
28 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26
29 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79
30 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45
31 INT219 Negative_regulation of Th 55 0.59 20.88 17.09
32 INT24241 Phosphorylation of Th 35 0.81 8.69 16.06
33 INT13716 Positive_regulation of TH 33 0.68 19.11 16
34 INT170308 Gene_expression of Ido1 159 0.75 69.51 15.98
35 INT20336 Positive_regulation of CYP2E1 48 0.70 19.26 15.66
36 INT615 Regulation of Alb 66 0.62 33.43 15.33
37 INT9904 Gene_expression of CYP2E1 64 0.78 13.11 14.65
38 INT109264 Positive_regulation of Transcription of Th 17 0.50 4.73 14.33
39 INT18773 Localization of ALB 117 0.80 69.18 13.8
40 INT31368 Positive_regulation of Positive_regulation of Th 19 0.51 2.2 12.68
41 INT141 Binding of Th 21 0.48 3.53 11.04
42 INT78567 Positive_regulation of Gene_expression of Th 25 0.68 5.32 10.75
43 INT2791 Regulation of Mb 53 0.61 23.03 10.73
44 INT2792 Gene_expression of Mb 91 0.76 41.56 10.25
45 INT48496 Regulation of Transcription of Th 16 0.54 2.29 10.02
46 INT181307 Gene_expression of NGB 1 0.76 11.15 9.18
47 INT860 Regulation of ALB 48 0.60 25.11 8.95
48 INT28521 Gene_expression of HBG2 56 0.77 16.62 8.64
49 INT4046 Positive_regulation of HBG2 42 0.69 13.66 8.51
50 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34
51 INT109265 Transcription of Th 18 0.68 4.5 8.21
52 INT26643 Negative_regulation of Positive_regulation of Th 12 0.59 1.26 7.74
53 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
54 INT170295 Positive_regulation of Ido1 40 0.67 28.89 7.61
55 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
56 INT248206 Gene_expression of Tdo2 15 0.78 9.17 7.16
57 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
58 INT7624 Positive_regulation of Regulation of Th 7 0.50 2.41 7
59 INT32709 Negative_regulation of Hbb 30 0.54 18.27 6.97
60 INT39418 Negative_regulation of Tdo2 12 0.57 0.8 6.93
61 INT63057 Regulation of CYP3A4 31 0.61 5.75 6.92
62 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88
63 INT3757 Positive_regulation of Gene_expression of ALB 45 0.69 23.73 6.85
64 INT109266 Negative_regulation of Transcription of Th 9 0.42 2.5 6.85
65 INT18759 Positive_regulation of Gene_expression of CYP2E1 22 0.70 5.02 6.84
66 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8
67 INT66987 Regulation of Th 23 0.61 7.86 6.8
68 INT3506 Localization of TH 12 0.81 0.78 6.66
69 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37
70 INT2442 Localization of Mb 38 0.80 24.74 6.33
71 INT7569 Positive_regulation of Transcription of Th 19 0.70 2.6 6.17
72 INT4422 Positive_regulation of Gene_expression of Alb 30 0.50 18.56 6.12
73 INT170315 Positive_regulation of Gene_expression of Ido1 50 0.67 25.39 6.06
74 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01
75 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99
76 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64
77 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45
78 INT30317 Regulation of TH 14 0.43 7.27 5.38
79 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37
80 INT65135 Binding of CYP2C19 17 0.48 1.82 5.2
81 INT7623 Regulation of Regulation of Th 11 0.44 1.31 5.16
82 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04
83 INT24236 Positive_regulation of Phosphorylation of Th 12 0.61 3.68 4.87
84 INT11298 Gene_expression of Ido1 6 0.58 6.71 4.85
85 INT37151 Localization of Th 13 0.57 3.11 4.82
86 INT170311 Negative_regulation of Ido1 16 0.48 14.47 4.81
87 INT143557 Positive_regulation of Ido1 6 0.40 5.34 4.8
88 INT114718 Positive_regulation of Gene_expression of CYP3A4 17 0.49 4.69 4.69
89 INT40620 Regulation of Positive_regulation of Th 9 0.45 2.45 4.69
90 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59
91 INT65881 Gene_expression of CYP2C19 21 0.76 1.19 4.57
92 INT23045 Positive_regulation of Hbb 31 0.64 19.35 4.54
93 INT59041 Negative_regulation of CYP2E1 17 0.59 5.47 4.51
94 INT37863 Regulation of HBG2 11 0.61 3.95 4.34
95 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3
96 INT30165 Positive_regulation of Phosphorylation of Th 8 0.56 0.75 4.22
97 INT44578 Binding of Hbb 19 0.48 3.12 4.2
98 INT19847 Positive_regulation of Localization of Alb 21 0.70 13.89 4.16
99 INT20230 Negative_regulation of Positive_regulation of Alb 15 0.56 12.44 4.11
100 INT158593 Negative_regulation of Negative_regulation of CYP3A4 5 0.43 1.16 4.01
101 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92
102 INT77823 Negative_regulation of Negative_regulation of Th 9 0.59 1.56 3.79
103 INT141658 Positive_regulation of Gene_expression of Sod2 51 0.69 35.6 3.71
104 INT99453 Gene_expression of SOD2 25 0.77 13.28 3.6
105 INT18192 Regulation of Gene_expression of Alb 16 0.44 9.38 3.57
106 INT22431 Negative_regulation of HBG2 20 0.58 6.6 3.33
107 INT30166 Regulation of Phosphorylation of Th 4 0.50 0.52 3.33
108 INT102901 Regulation of Gene_expression of Th 12 0.60 2.42 3.22
109 INT23044 Gene_expression of Hbb 13 0.43 5.77 3.1
110 INT100785 Protein_catabolism of CYP3A4 7 1.00 0.76 3.01
111 INT133809 Negative_regulation of Gene_expression of CYP19A1 9 0.43 7.67 2.99
112 INT113277 Positive_regulation of Gene_expression of CYP19A1 13 0.69 10.23 2.97
113 INT4782 Positive_regulation of Gene_expression of TH 12 0.47 7.36 2.95
114 INT15557 Regulation of Localization of Alb 13 0.50 5.71 2.91
115 INT22212 Gene_expression of CYP1A1 34 0.76 10.11 2.77
116 INT155216 Negative_regulation of Gene_expression of CYP3A4 9 0.56 3.81 2.71
117 INT4647 Regulation of Hbb 10 0.60 5.28 2.66
118 INT2021 Binding of HBG2 13 0.36 4.2 2.65
119 INT106066 Negative_regulation of Positive_regulation of TH 1 0.18 0.22 2.6
120 INT106068 Positive_regulation of Positive_regulation of TH 1 0.21 0.22 2.59
121 INT4704 Positive_regulation of Negative_regulation of Th 4 0.50 0.06 2.56
122 INT23954 Negative_regulation of Mb 24 0.49 11.27 2.55
123 INT13644 Negative_regulation of Phosphorylation of Th 2 0.43 0.06 2.51
124 INT184914 Negative_regulation of Gene_expression of Th 15 0.43 9.17 2.46
125 INT62653 Positive_regulation of CYP2C19 8 0.54 1.23 2.41
126 INT122709 Localization of CYP3A4 16 0.75 5.41 2.38
127 INT31134 Regulation of Binding of ALB 13 0.62 2.51 2.37
128 INT15210 Negative_regulation of Transcription of Th 9 0.59 0.47 2.37
129 INT170323 Regulation of Gene_expression of Ido1 11 0.60 8.74 2.33
130 INT4210 Gene_expression of MB 24 0.78 11.74 2.32
131 INT19537 Negative_regulation of Binding of ALB 6 0.43 3.32 2.26
132 INT646 Binding of Mb 37 0.41 6.13 2.25
133 INT28191 Positive_regulation of Positive_regulation of CYP2E1 5 0.49 3.5 2.25
134 INT9188 Localization of HBG1 12 0.75 8.14 2.24
135 INT71048 Transcription of CYP19A1 11 0.72 8.74 2.24
136 INT142626 Negative_regulation of Localization of ALB 9 0.55 6.63 2.24
137 INT15209 Negative_regulation of Regulation of Th 6 0.51 1.64 2.16
138 INT7206 Binding of HBG1 14 0.47 3.44 2.14
139 INT109334 Regulation of SOD2 13 0.60 7.48 2.14
140 INT111113 Binding of CYP19A1 15 0.36 9.17 2.12
141 INT58108 Positive_regulation of Positive_regulation of ALB 4 0.70 1.02 2.11
142 INT45396 Positive_regulation of Tdo2 6 0.61 0.92 2.1
143 INT9906 Binding of CYP2E1 15 0.40 1.89 2.08
144 INT117898 Positive_regulation of Protein_catabolism of CYP3A4 1 0.67 0 2.08
145 INT36616 Positive_regulation of Binding of ALB 8 0.67 3 2.07
146 INT28188 Regulation of CYP2E1 11 0.62 0.48 2.03
147 INT149263 Regulation of Negative_regulation of CYP3A4 4 0.44 1 2.03
148 INT90688 Negative_regulation of Tdo2 12 0.59 5.82 2.02
149 INT36267 Positive_regulation of CYP1A1 29 0.69 11.09 2.01
150 INT36779 Localization of HBG2 3 0.59 1.57 2
151 INT1834 Positive_regulation of Binding of Th 1 0.46 0 1.91
152 INT143561 Positive_regulation of Positive_regulation of Ido1 1 0.36 1.84 1.89
153 INT90687 Gene_expression of Tdo2 1 0.64 0.88 1.86
154 INT314510 Protein_catabolism of TH 1 0.10 3.28 1.86
155 INT3505 Binding of TH 5 0.39 2.6 1.8
156 INT183753 Regulation of HBM 24 0.39 13.13 1.79
157 INT150248 Positive_regulation of Gene_expression of Ido1 2 0.43 2.68 1.77
158 INT181309 Positive_regulation of Gene_expression of NGB 1 0.46 1.84 1.65
159 INT145545 Transcription of TH 3 0.67 1.48 1.64
160 INT11567 Negative_regulation of Localization of Alb 17 0.48 7.69 1.56
161 INT11365 Positive_regulation of Localization of Mb 5 0.38 3.78 1.54
162 INT124299 Negative_regulation of Gene_expression of Sod2 15 0.53 13.8 1.51
163 INT178615 Binding of SOD2 12 0.48 6.93 1.51
164 INT87095 Positive_regulation of Gene_expression of CYP2C19 3 0.48 0 1.5
165 INT93956 Binding of HBM 20 0.35 8.86 1.48
166 INT127889 Regulation of Gene_expression of CYP19A1 11 0.62 6.7 1.41
167 INT2790 Regulation of Gene_expression of Mb 7 0.61 1.61 1.39
168 INT22540 Negative_regulation of Binding of Alb 8 0.59 0.56 1.34
169 INT93863 Transcription of CYP2E1 3 0.69 1.39 1.34
170 INT186268 Positive_regulation of Tdo2 13 0.50 8 1.32
171 INT49978 Localization of Hbb 4 0.39 1.11 1.29
172 INT117897 Negative_regulation of Protein_catabolism of CYP3A4 1 0.55 0 1.28
173 INT11367 Localization of MB 9 0.78 9.34 1.24
174 INT97869 Negative_regulation of Positive_regulation of Th 3 0.25 0.79 1.23
175 INT134061 Transcription of Sod2 5 0.68 3.46 1.19
176 INT70763 Protein_catabolism of Alb 6 0.88 1.84 1.17
177 INT72558 Regulation of CYP2C19 6 0.54 1.97 1.14
178 INT26760 Negative_regulation of Localization of Th 2 0.40 0.09 1.14
179 INT165310 Negative_regulation of Transcription of CYP2E1 1 0.42 1.15 1.14
180 INT7207 Regulation of HBG1 27 0.60 22.1 1.12
181 INT22893 Negative_regulation of Positive_regulation of Mb 6 0.47 1.51 1.12
182 INT50267 Negative_regulation of Negative_regulation of Th 3 0.42 1.57 1.12
183 INT89670 Negative_regulation of Binding of Th 2 0.43 0.28 1.12
184 INT220046 Positive_regulation of Negative_regulation of Ido1 1 0.41 2.98 1.12
185 INT38706 Positive_regulation of Positive_regulation of Alb 4 0.46 3.53 1.11
186 INT96873 Gene_expression of CYP1B1 28 0.78 11.81 1.09
187 INT3414 Positive_regulation of Negative_regulation of Alb 4 0.44 1.91 1.09
188 INT39419 Positive_regulation of Negative_regulation of Tdo2 3 0.43 0.19 1.09
189 INT45133 Regulation of Binding of Alb 4 0.45 0.55 1.07
190 INT58856 Positive_regulation of Gene_expression of MB 4 0.50 4.56 1.06
191 INT9075 Regulation of Positive_regulation of ALB 3 0.45 0.76 1.06
192 INT79928 Positive_regulation of Localization of ALB 10 0.60 8.96 1.05
193 INT125541 Transcription of CYP3A4 7 0.69 2.14 1.02
194 INT88177 Negative_regulation of Ido1 3 0.25 0.51 1.02
195 INT68220 Binding of CYP1A1 8 0.48 0.8 0.99
196 INT8772 Positive_regulation of Gene_expression of HBG1 16 0.68 6.93 0.95
197 INT208792 Negative_regulation of Gene_expression of TH 6 0.35 1.11 0.94
198 INT198953 Regulation of Regulation of Th 1 0.01 0.1 0.93
199 INT57596 Regulation of Gene_expression of ALB 9 0.44 5.44 0.91
200 INT124300 Negative_regulation of Sod2 17 0.45 12.54 0.9
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