GO:0019852

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Name L-ascorbic acid metabolic process
Categary Process
Go Slim No
Go Link GO:0019852
Unique Molecular Interactions 12
Total Molecular Interactions 12
Total Single Events 196
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for L-ascorbic acid metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for L-ascorbic acid metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT31776 Positive_regulation of Gclc Positive_regulation of G6pd 1 0.29 0.19 0.75
2 INT148465 Positive_regulation of Ccl4 Positive_regulation of Gclc 1 0.32 0.06 0.38
3 INT148467 Ccl4 Positive_regulation of Gclc 1 0.32 0.05 0.37
4 INT101812 Binding of KEAP1 and Positive_regulation of Gene_expression of GCLC 1 0.54 0.1 0.19
5 INT101808 Binding of NFE2L2 and Positive_regulation of Gene_expression of GCLC 1 0.54 0.1 0.19
6 INT101809 Gene_expression of NFE2L2 Positive_regulation of Gene_expression of GCLC 1 0.75 0 0.12
7 INT101811 NFE2L2 Regulation of Gene_expression of GCLC 1 0.67 0.06 0.12
8 INT101807 Gene_expression of KEAP1 Negative_regulation of Positive_regulation of GCLC 1 0.46 0 0.08
9 INT89724 RYBP Positive_regulation of Gclc 1 0.01 0.21 0.07
10 INT267046 Binding of SLC2A1 and SV2A 1 0.12 0 0.05
11 INT284098 HNF1A Positive_regulation of SLC2A1 1 0.36 1.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for L-ascorbic acid metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in L-ascorbic acid metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT38251 Negative_regulation of Gclc 7 0.57 1.37 5.06
2 INT100886 Gene_expression of GCLC 16 0.76 5.63 2.29
3 INT14010 Gene_expression of SLC2A1 19 0.78 15.22 2.12
4 INT100897 Positive_regulation of Gene_expression of GCLC 9 0.68 1.84 1.99
5 INT41395 Positive_regulation of Gclc 9 0.61 1.34 1.66
6 INT100892 Positive_regulation of GCLC 8 0.68 3.44 1.08
7 INT11198 Negative_regulation of Gclc 3 0.59 0.49 0.87
8 INT94194 Transcription of Gclc 1 0.58 0.53 0.87
9 INT31775 Positive_regulation of Gclc 3 0.38 0.52 0.84
10 INT13654 Regulation of SLC2A1 1 0.44 0.44 0.68
11 INT61226 Binding of Gclc 1 0.14 0 0.67
12 INT41394 Regulation of Gclc 5 0.43 1.78 0.64
13 INT7630 Negative_regulation of SLC2A1 4 0.45 0.73 0.56
14 INT147960 Negative_regulation of GCLC 8 0.28 4.4 0.45
15 INT347246 Positive_regulation of Gene_expression of SLC2A1 1 0.21 0.28 0.32
16 INT347245 Regulation of Gene_expression of SLC2A1 1 0.14 0.28 0.32
17 INT96952 Gene_expression of Gclc 7 0.38 2.08 0.28
18 INT101822 Negative_regulation of Positive_regulation of GCLC 1 0.57 0.07 0.23
19 INT136401 Binding of SLC2A1 2 0.36 1.75 0.22
20 INT96951 Positive_regulation of Gene_expression of Gclc 5 0.34 1.45 0.16
21 INT101819 Positive_regulation of Positive_regulation of GCLC 2 0.59 1.47 0.15
22 INT158977 Transcription of SLC2A1 6 0.53 3.44 0.06
23 INT158982 Positive_regulation of Transcription of SLC2A1 3 0.45 1.66 0.06
24 INT261026 Localization of Gclc 3 0.36 0.88 0.06
25 INT261017 Regulation of Gclc 2 0.22 0.88 0.06
26 INT296982 Positive_regulation of SLC2A1 3 0.53 1.95 0
27 INT186262 Transcription of GCLC 3 0.23 1.19 0
28 INT319631 Positive_regulation of Transcription of Gclc 1 0.17 0 0
29 INT261016 Regulation of Positive_regulation of Gclc 1 0.22 0.23 0
30 INT319621 Transcription of Gclc 1 0.20 0 0
31 INT261006 Positive_regulation of Positive_regulation of Gclc 1 0.24 0.23 0
32 INT313321 Negative_regulation of Transcription of GCLC 1 0.15 0 0
33 INT158981 Regulation of Transcription of SLC2A1 1 0.20 0 0
34 INT290825 Negative_regulation of Gene_expression of SLC2A1 1 0.29 0.32 0
35 INT246068 Regulation of GCLC 1 0.24 0.11 0
36 INT267062 Negative_regulation of Binding of SLC2A1 1 0.14 0 0
37 INT311771 Negative_regulation of Positive_regulation of SLC2A1 1 0.33 0.17 0
38 INT261005 Regulation of Localization of Gclc 1 0.13 0.39 0
39 INT261027 Binding of Gclc 1 0.18 0 0
40 INT315103 Localization of SLC2A1 1 0.51 0.26 0
41 INT261022 Regulation of Gene_expression of Gclc 1 0.22 0.23 0
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