GO:0019870

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Name potassium channel inhibitor activity
Categary Function
Go Slim No
Go Link GO:0019870
Unique Molecular Interactions 14
Total Molecular Interactions 14
Total Single Events 293
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for potassium channel inhibitor activity. They are ordered first by their pain relevance and then by number of times they were reported for potassium channel inhibitor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
2 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
3 INT65631 Ufm1 Positive_regulation of Kcna5 1 0.02 0 0.99
4 INT120870 Binding of Wnk1 and Sptlc1 1 0.14 1.24 0.56
5 INT164973 Binding of RASA1 and Rgs7 1 0.00 0 0.54
6 INT164972 Binding of RASA1 and Rgs8 1 0.00 0 0.53
7 INT270664 Ensa Positive_regulation of Localization of Ins1 1 0.02 0.89 0.05
8 INT270659 Wnk1 Regulation of Napg 1 0.04 1.12 0.04
9 INT270661 Regulation of Wnk1 Regulation of Napg 1 0.04 1.13 0.04
10 INT225892 Binding of GAB1 and RASA1 1 0.01 0.06 0
11 INT331235 RASA1 Positive_regulation of Mtor 1 0.00 0.32 0
12 INT293795 Binding of RASA1 and ras 1 0.00 0.08 0
13 INT331236 Binding of RASA1 and Mtor 1 0.00 0.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for potassium channel inhibitor activity. They are ordered first by their pain relevance and then by number of times they were reported in potassium channel inhibitor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48540 Gene_expression of Kcna5 37 0.77 14.04 16.07
2 INT65627 Negative_regulation of Kcna5 19 0.59 7.82 10.79
3 INT65630 Regulation of Kcna5 11 0.62 6.61 7.22
4 INT48541 Positive_regulation of Kcna5 12 0.69 5.51 6.35
5 INT65628 Regulation of Gene_expression of Kcna5 4 0.61 1.66 2.98
6 INT65629 Positive_regulation of Gene_expression of Kcna5 5 0.69 2.48 2.76
7 INT116215 Transcription of Kcna5 6 0.53 3.62 2.75
8 INT116216 Negative_regulation of Gene_expression of Kcna5 4 0.43 3.11 2.64
9 INT17993 Negative_regulation of RASA1 8 0.41 7.34 2.62
10 INT99800 Binding of Kcna5 4 0.47 0.96 2.55
11 INT43900 Gene_expression of RASA1 13 0.58 12 2.03
12 INT131751 Localization of Kcna5 1 0.71 0 1.7
13 INT14916 Binding of RASA1 15 0.37 13.64 1.44
14 INT126635 Negative_regulation of Alox15 2 0.41 0.67 1.43
15 INT99801 Regulation of Binding of Kcna5 1 0.26 0.14 0.9
16 INT62688 Binding of Wnk1 2 0.17 2.83 0.63
17 INT90416 Positive_regulation of RASA1 3 0.67 1.58 0.56
18 INT107996 Negative_regulation of Regulation of Kcna5 1 0.12 0.67 0.54
19 INT7248 Localization of RASA1 4 0.61 2.52 0.47
20 INT116214 Regulation of Transcription of Kcna5 1 0.27 0.52 0.44
21 INT90168 Regulation of Wnk1 2 0.04 0.63 0.29
22 INT201013 Regulation of Gene_expression of RASA1 1 0.05 0.16 0.16
23 INT201009 Transcription of RASA1 1 0.07 0.14 0.12
24 INT150030 Negative_regulation of Gene_expression of Alox15 1 0.11 0.05 0.07
25 INT131835 Positive_regulation of Wnk1 1 0.07 1.28 0.07
26 INT150029 Gene_expression of Alox15 1 0.18 0 0.04
27 INT225851 Phosphorylation of RASA1 2 0.05 0.14 0
28 INT144997 Negative_regulation of Wnk1 1 0.08 0 0
29 INT291974 Regulation of RASA1 1 0.03 0.29 0
30 INT262506 Phosphorylation of Kcna5 1 0.26 0.59 0
31 INT335031 Positive_regulation of Gene_expression of RASA1 1 0.09 1.49 0
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