GO:0019903

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Name protein phosphatase binding
Categary Function
Go Slim No
Go Link GO:0019903
Unique Molecular Interactions 1278
Total Molecular Interactions 1801
Total Single Events 15882
Pain Genes Associated 70

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein phosphatase binding. They are ordered first by their pain relevance and then by number of times they were reported for protein phosphatase binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
2 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
3 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
4 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
5 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
6 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
7 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
8 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
9 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23
10 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
11 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
12 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
13 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
14 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
15 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
16 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
17 INT169570 Binding of ROS1 and TRPV1 3 0.33 3.07 1.89
18 INT349588 Aap Positive_regulation of Gene_expression of Ros1 1 0.06 0.73 1.85
19 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
20 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
21 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71
22 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71
23 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
24 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
25 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
26 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
27 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
28 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
29 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
30 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
31 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
32 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
33 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
34 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
35 INT349586 Aap Regulation of Gene_expression of Ros1 1 0.03 0.56 1.17
36 INT69824 Negative_regulation of Binding of GHR and RYBP 1 0.01 0 1.14
37 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
38 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
39 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
40 INT119276 Negative_regulation of CYBB Negative_regulation of Positive_regulation of ROS1 1 0.09 1.18 0.97
41 INT119275 Negative_regulation of CYBB Negative_regulation of Gene_expression of ROS1 1 0.09 1.18 0.97
42 INT45279 Binding of CSF2 and GHR 1 0.05 0.07 0.93
43 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
44 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
45 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
46 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
47 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
48 INT169469 Binding of Egfr and Tgfa 1 0.19 1.87 0.91
49 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
50 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
51 INT199189 Binding of Aldh2 and Ros1 1 0.06 0.3 0.88
52 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
53 INT119274 CYBB Positive_regulation of ROS1 1 0.11 1.11 0.88
54 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87
55 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
56 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
57 INT120820 Binding of ASIC3 and Dlg4 3 0.02 0.11 0.84
58 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
59 INT155760 Binding of Nos1 and Dlg4 1 0.13 1.01 0.82
60 INT73775 Binding of GH1 and GHR 4 0.35 0.68 0.8
61 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
62 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8
63 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
64 INT114068 Agtr2 Regulation of Gene_expression of Insr 1 0.15 0.95 0.79
65 INT152947 Dlg4 Regulation of Sgk1 1 0.09 0.18 0.76
66 INT152945 Dlg4 Regulation of Cap1 1 0.11 0.18 0.76
67 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
68 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
69 INT73776 Regulation of Binding of GH1 and GHR 2 0.26 0.16 0.75
70 INT152944 Dlg4 Regulation of Gpr88 1 0.12 0.18 0.75
71 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
72 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73
73 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72
74 INT337157 Iqgap1 Regulation of Gene_expression of Ros1 1 0.07 1.91 0.72
75 INT275285 Ros1 Positive_regulation of Tnfrsf1a 1 0.27 1.06 0.72
76 INT317573 Binding of Oprm1 and Pik3r1 1 0.12 0.33 0.71
77 INT275288 Trpv1 Positive_regulation of Gene_expression of Ros1 1 0.21 0.7 0.71
78 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7
79 INT12238 CCK Positive_regulation of CDH2 1 0.02 0 0.7
80 INT190527 TNF Positive_regulation of Gene_expression of Ros1 1 0.01 1.02 0.68
81 INT313993 Ros1 Positive_regulation of Nfkb1 1 0.05 1.61 0.68
82 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
83 INT169213 Binding of EGFR and CARTPT 1 0.00 0.22 0.67
84 INT168205 Binding of Dlg4 and Pik3cd 1 0.11 0.37 0.65
85 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65
86 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
87 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
88 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64
89 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64
90 INT309664 Binding of Pik3r1 and Cia1 1 0.02 1.32 0.64
91 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64
92 INT158685 ROS1 Regulation of Positive_regulation of MAPK8 1 0.21 0.39 0.64
93 INT116752 Ngf Regulation of Pik3r1 1 0.56 0.29 0.63
94 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62
95 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
96 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
97 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
98 INT149929 Cyp2e1 Positive_regulation of Gene_expression of Ros1 1 0.12 0 0.61
99 INT166387 Binding of Gnb2l1 and Mdk 1 0.30 0.24 0.61
100 INT166385 Binding of Araf and Gnb2l1 1 0.23 0.24 0.6
101 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
102 INT324925 Ros1 Positive_regulation of Bdkrb1 1 0.08 0.67 0.6
103 INT327992 TRPV1 Positive_regulation of Gene_expression of ROS1 1 0.28 0.35 0.6
104 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
105 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
106 INT118001 Csk Regulation of Trpv1 1 0.08 0.09 0.58
107 INT169286 CNR1 Positive_regulation of Phosphorylation of EGFR 1 0.45 0.18 0.57
108 INT145429 oh Positive_regulation of Positive_regulation of Ros1 1 0.01 0.07 0.57
109 INT112107 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2a 1 0.40 0.49 0.57
110 INT145431 Pax3 Positive_regulation of Positive_regulation of Ros1 1 0.02 0.07 0.57
111 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56
112 INT112106 Negative_regulation of Dlg2 Negative_regulation of Grin2a 1 0.40 0.48 0.56
113 INT251141 Binding of Dlg4 and Grin2b 1 0.14 0.32 0.55
114 INT251143 Binding of Grin2b and Dlg3 1 0.22 0.32 0.55
115 INT251151 Binding of Grin2a and Dlg3 1 0.24 0.32 0.54
116 INT321842 Binding of Ros1 and SCFV 1 0.01 1.34 0.54
117 INT352891 Binding of ROS1 and GOPC 1 0.09 1.34 0.53
118 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
119 INT317565 Oprm1 Positive_regulation of Pik3r1 1 0.14 0.05 0.52
120 INT114070 Agtr2 Positive_regulation of Gene_expression of Insr 1 0.13 0.34 0.52
121 INT5856 Bad Positive_regulation of Gene_expression of Penk 1 0.02 0.37 0.5
122 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5
123 INT122107 Plbd2 Negative_regulation of Cdh2 1 0.03 0.42 0.5
124 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49
125 INT275282 Ros1 Regulation of Positive_regulation of Trpv1 1 0.16 0.55 0.49
126 INT275286 Ros1 Regulation of Positive_regulation of Tnfrsf1a 1 0.16 0.55 0.49
127 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48
128 INT317834 Binding of Pstpip1 and Il1 1 0.00 2.03 0.48
129 INT263746 Binding of Dlg4 and Neto1 1 0.27 0 0.48
130 INT146578 Hba Negative_regulation of Ros1 1 0.04 0.51 0.47
131 INT173475 Bcar1 Regulation of Isl1 1 0.01 0 0.47
132 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
133 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
134 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
135 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
136 INT311557 Binding of ROS1 and Ptpn2 1 0.02 2.32 0.46
137 INT346913 Binding of Kars and Positive_regulation of Gene_expression of Ros1 1 0.03 1.25 0.46
138 INT198931 Binding of Dlg4 and Lrp8 1 0.06 0.23 0.46
139 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
140 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
141 INT244050 Binding of Gnb2l1 and Prkca 1 0.01 0 0.45
142 INT241914 SOD1 Positive_regulation of Ros1 1 0.00 0.76 0.44
143 INT241912 Cat Positive_regulation of Ros1 1 0.03 0.76 0.44
144 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43
145 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
146 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
147 INT342998 DUOX1 Positive_regulation of ROS1 1 0.23 0.25 0.43
148 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
149 INT296477 Binding of Cacng2 and Dlg4 1 0.04 0.22 0.42
150 INT135426 Binding of APBB1 and Dlg4 1 0.00 0.17 0.42
151 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
152 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
153 INT121851 AKT1 Regulation of ROS1 1 0.16 0.52 0.41
154 INT342181 Binding of Igfals and Ros1 1 0.01 0.76 0.41
155 INT121856 BID Regulation of ROS1 1 0.05 0.52 0.41
156 INT330110 Racgap1 Regulation of Gene_expression of Ros1 1 0.00 1.12 0.41
157 INT326473 Positive_regulation of PGAP1 Positive_regulation of ROS1 1 0.00 0.07 0.41
158 INT121855 CASP8 Regulation of ROS1 1 0.05 0.52 0.41
159 INT338044 F2 Positive_regulation of Pard3 1 0.08 0.38 0.4
160 INT121853 Gene_expression of ROS1 Negative_regulation of AKT1 1 0.25 0.49 0.4
161 INT326470 PGAP1 Positive_regulation of ROS1 1 0.00 0.07 0.4
162 INT327991 Positive_regulation of TRPV1 Positive_regulation of ROS1 1 0.26 0.2 0.4
163 INT187519 ATIC Negative_regulation of Gene_expression of Ros1 1 0.00 1.48 0.39
164 INT114067 Ace Regulation of Insr 1 0.09 0.31 0.39
165 INT166157 Ccr9 Positive_regulation of Pik3r1 1 0.55 2.14 0.39
166 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
167 INT118002 Binding of Trpv1 and Csk 1 0.06 0.08 0.38
168 INT272751 EGFR Regulation of Negative_regulation of Prkca 1 0.01 0 0.38
169 INT215275 Tlr4 Positive_regulation of Gene_expression of Ros1 1 0.01 1.37 0.38
170 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
171 INT324813 Tlr4 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
172 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
173 INT275287 Ros1 Positive_regulation of Trpv1 1 0.26 0.4 0.37
174 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
175 INT324827 Hmgb1 Positive_regulation of Bad 1 0.02 0.43 0.36
176 INT120821 Dlg4 Positive_regulation of ASIC3 1 0.02 0 0.36
177 INT324808 Tlr4 Positive_regulation of Bad 1 0.02 0.43 0.36
178 INT336573 Ptpn2 Regulation of INSR 1 0.00 1.36 0.36
179 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
180 INT242403 INSR Positive_regulation of Gene_expression of Bdkrb1 1 0.45 0.88 0.35
181 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
182 INT187488 Positive_regulation of Ros1 Positive_regulation of Gene_expression of Nos2 1 0.01 0.88 0.35
183 INT272602 Binding of Dlg4 and Gria2 3 0.09 0.19 0.34
184 INT175988 Ros1 Positive_regulation of Transcription of Gtf3a 1 0.01 1.56 0.34
185 INT120817 Binding of Dlg4 and Lin7b 1 0.00 0 0.34
186 INT183793 INS Negative_regulation of Binding of Ros1 1 0.16 1.66 0.34
187 INT296465 Binding of Dlg4 and Rbm39 1 0.00 0.05 0.34
188 INT134080 OPA1 Negative_regulation of Phosphorylation of Gnb2l1 1 0.03 0.22 0.34
189 INT173476 Th Regulation of Gene_expression of Bcar1 1 0.10 0 0.34
190 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
191 INT23882 Npy Positive_regulation of Bcar1 1 0.34 0.67 0.34
192 INT175990 Ros1 Positive_regulation of Gene_expression of Gtf3a 1 0.01 1.56 0.34
193 INT288200 Tlr2 Positive_regulation of Pik3r1 1 0.05 0.24 0.33
194 INT324525 PGE Positive_regulation of Positive_regulation of Egfr 1 0.41 1.05 0.33
195 INT324522 PGE Positive_regulation of Phosphorylation of Egfr 1 0.56 1.04 0.33
196 INT168779 Binding of Pik3r1 and Tnf 1 0.01 0.73 0.33
197 INT324524 PGE Positive_regulation of Egfr 1 0.38 1.05 0.33
198 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
199 INT147436 Agt Positive_regulation of Gene_expression of Ros1 1 0.02 0.5 0.33
200 INT283841 Dlg4 Negative_regulation of Insrr 1 0.01 0.95 0.33

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein phosphatase binding. They are ordered first by their pain relevance and then by number of times they were reported in protein phosphatase binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83
2 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
3 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5
4 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98
5 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
6 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
7 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
8 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56
9 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
10 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08
11 INT8691 Localization of Insr 85 0.80 9.27 30.32
12 INT5300 Regulation of Insr 54 0.60 11.33 29.26
13 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45
14 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21
15 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
16 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27
17 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
18 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91
19 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
20 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
21 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
22 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
23 INT97100 Negative_regulation of Dlg4 16 0.58 6.18 14.36
24 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71
25 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
26 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32
27 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
28 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
29 INT88789 Gene_expression of Dlg4 26 0.78 4.41 12.74
30 INT55343 Localization of Ros1 39 0.60 34.51 12.5
31 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22
32 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
33 INT112003 Localization of ROS1 94 0.73 66.32 12.16
34 INT100821 Localization of Ros1 59 0.60 45.26 11.92
35 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
36 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55
37 INT244490 Gene_expression of HSP90B1 4 0.33 41.16 10.37
38 INT94784 Binding of ROS1 113 0.40 71.57 10.26
39 INT158863 Negative_regulation of Ros1 84 0.35 40.3 10.14
40 INT159116 Gene_expression of Gnb2l1 12 0.77 2.79 9.49
41 INT56292 Negative_regulation of Gene_expression of Ros1 70 0.38 36.14 9.17
42 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93
43 INT141185 Regulation of Ros1 30 0.24 20.73 8.88
44 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
45 INT108643 Gene_expression of Dlg4 61 0.76 8.63 8.58
46 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
47 INT112099 Negative_regulation of Dlg2 2 0.40 6.17 8.16
48 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
49 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
50 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59
51 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
52 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33
53 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
54 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
55 INT166383 Positive_regulation of Gene_expression of Gnb2l1 1 0.69 2.19 7.02
56 INT97099 Positive_regulation of Dlg4 13 0.60 3.04 6.98
57 INT69439 Regulation of ROS1 46 0.45 31.22 6.94
58 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
59 INT69441 Regulation of Gene_expression of ROS1 38 0.50 26.78 6.78
60 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
61 INT88786 Binding of Dlg4 11 0.46 2.73 6.58
62 INT13385 Gene_expression of Bad 60 0.76 41.86 6.52
63 INT112101 Gene_expression of Dlg2 9 0.73 5.06 6.5
64 INT11154 Binding of EGFR 149 0.48 96.23 6.29
65 INT38595 Localization of BCAR1 8 0.73 2.9 6.25
66 INT143357 Binding of Ros1 48 0.36 27.76 6
67 INT251134 Binding of Dlg2 6 0.31 4.26 5.99
68 INT91159 Negative_regulation of Ros1 35 0.44 26.12 5.97
69 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
70 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
71 INT9895 Binding of GHR 18 0.36 4.8 5.65
72 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61
73 INT159115 Negative_regulation of Gene_expression of Gnb2l1 3 0.42 1.33 5.59
74 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56
75 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
76 INT115528 Binding of Ros1 37 0.41 22.96 5.5
77 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23
78 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
79 INT116744 Binding of Pik3r1 22 0.36 12.77 5.01
80 INT114058 Negative_regulation of Gene_expression of Insr 13 0.31 9.23 4.97
81 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93
82 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
83 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84
84 INT88790 Negative_regulation of Gene_expression of Dlg4 6 0.59 1.53 4.66
85 INT116748 Positive_regulation of Gene_expression of Pik3r1 18 0.49 9.83 4.63
86 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
87 INT159122 Positive_regulation of Gnb2l1 8 0.69 2.2 4.61
88 INT1807 Negative_regulation of Bcar1 9 0.38 4.04 4.59
89 INT145532 Localization of Dlg4 25 0.79 1.97 4.36
90 INT155689 Phosphorylation of Ros1 6 0.32 5.1 4.36
91 INT116747 Regulation of Pik3r1 18 0.60 9.33 4.34
92 INT103914 Phosphorylation of Egfr 35 0.82 16.98 4.31
93 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
94 INT91158 Regulation of Ros1 26 0.25 17 4.23
95 INT51084 Binding of Insr 13 0.30 4.25 4.23
96 INT33229 Gene_expression of Bad 9 0.70 6.95 4.15
97 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13
98 INT95512 Transcription of Ghr 24 0.69 3.1 4.12
99 INT83035 Binding of INSR 16 0.47 9.29 4.11
100 INT88787 Transcription of Dlg4 4 0.69 0.83 4.09
101 INT51654 Regulation of Bad 21 0.40 12.18 4.06
102 INT120810 Binding of Dlg4 38 0.41 3.55 4.03
103 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02
104 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77
105 INT160828 Regulation of Gene_expression of Ros1 29 0.21 13.97 3.75
106 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
107 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67
108 INT10116 Localization of INSR 11 0.57 5.43 3.48
109 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45
110 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
111 INT69438 Negative_regulation of Positive_regulation of ROS1 20 0.48 10.6 3.33
112 INT133086 Positive_regulation of Phosphorylation of Map2k7 1 0.05 4.34 3.27
113 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23
114 INT165911 Localization of Pik3r1 15 0.51 7.94 3.2
115 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
116 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
117 INT140555 Positive_regulation of Localization of ROS1 29 0.55 23.82 3.14
118 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12
119 INT124736 Positive_regulation of Gene_expression of Insr 6 0.31 7.55 3.12
120 INT244512 Positive_regulation of Gene_expression of HSP90B1 2 0.30 12.08 3.12
121 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11
122 INT276520 Gene_expression of Iqgap1 2 0.76 8.67 3.1
123 INT117348 Regulation of EGFR 75 0.61 47.73 3.09
124 INT38594 Positive_regulation of Localization of BCAR1 3 0.63 0.44 3.07
125 INT133082 Phosphorylation of Map2k7 5 0.15 4.27 3.05
126 INT105884 Binding of Bcl2 19 0.35 15.67 3
127 INT3437 Negative_regulation of Bad 5 0.48 1.66 2.99
128 INT59905 Gene_expression of Ghr 29 0.63 9.25 2.97
129 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
130 INT195978 Gene_expression of Hsp90b1 26 0.65 11.28 2.88
131 INT140378 Negative_regulation of Irs2 4 0.57 1.77 2.86
132 INT166381 Negative_regulation of Gnb2l1 1 0.43 0.73 2.68
133 INT87340 Negative_regulation of BCAR1 8 0.38 6.96 2.63
134 INT163405 Positive_regulation of Binding of ROS1 15 0.27 9.39 2.58
135 INT29983 Localization of Bad 5 0.28 4.44 2.52
136 INT99548 Positive_regulation of Gene_expression of CDKN1B 12 0.67 6.79 2.5
137 INT23527 Negative_regulation of Localization of Insr 10 0.39 2.58 2.5
138 INT251126 Regulation of Dlg2 1 0.40 1.56 2.46
139 INT108333 Phosphorylation of BAD 43 0.68 33.77 2.45
140 INT61378 Positive_regulation of Bcar1 13 0.45 2.84 2.45
141 INT22019 Regulation of GHR 9 0.62 2.56 2.39
142 INT159117 Regulation of Gene_expression of Gnb2l1 3 0.56 0.5 2.36
143 INT109305 Phosphorylation of Pik3r1 13 0.53 5.69 2.32
144 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
145 INT16286 Positive_regulation of GHR 8 0.60 4.04 2.31
146 INT128926 Gene_expression of Map2k7 5 0.23 3.01 2.31
147 INT67352 Transcription of Ghr 8 0.61 1.55 2.3
148 INT172808 Positive_regulation of Positive_regulation of ROS1 35 0.40 31.39 2.27
149 INT95621 Gene_expression of Gck 6 0.64 1.06 2.26
150 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
151 INT251127 Regulation of Gene_expression of Dlg2 1 0.35 1.49 2.23
152 INT111038 Gene_expression of Cdkn1b 23 0.75 25.35 2.22
153 INT129871 Positive_regulation of Gene_expression of Gck 1 0.28 0.15 2.19
154 INT103917 Positive_regulation of Phosphorylation of Egfr 12 0.68 7.23 2.18
155 INT24621 Regulation of Gene_expression of Insr 9 0.42 2.68 2.18
156 INT114421 Positive_regulation of Positive_regulation of Pik3r1 9 0.49 4.07 2.13
157 INT134874 Regulation of Dlg4 3 0.58 0.28 2.12
158 INT169705 Negative_regulation of Gene_expression of Cdh1 10 0.57 8.8 2.1
159 INT172874 Phosphorylation of Bad 31 0.80 27.46 2.07
160 INT95510 Regulation of Ghr 1 0.45 0.21 2.07
161 INT31006 Regulation of Localization of Insr 7 0.50 0.2 2.05
162 INT156093 Negative_regulation of Positive_regulation of Ros1 8 0.23 5.17 2.03
163 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
164 INT195968 Positive_regulation of Gene_expression of Hsp90b1 10 0.49 5.21 2.02
165 INT127944 Negative_regulation of Localization of ROS1 8 0.36 3.14 2.02
166 INT251128 Regulation of Negative_regulation of Dlg2 1 0.24 1.97 2.01
167 INT4643 Negative_regulation of GHR 10 0.45 3.01 2
168 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
169 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96
170 INT204139 Positive_regulation of Gene_expression of BCAR1 1 0.23 0.9 1.96
171 INT134628 Gene_expression of Flt4 9 0.48 7.52 1.94
172 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9
173 INT148788 Binding of Csk 2 0.12 2.14 1.89
174 INT65545 Localization of EGFR 35 0.79 20.8 1.88
175 INT114059 Localization of Insr 10 0.46 3.49 1.87
176 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
177 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
178 INT118511 Gene_expression of Pard3 5 0.57 0.76 1.86
179 INT112131 Positive_regulation of Positive_regulation of Egfr 10 0.49 9.95 1.85
180 INT198748 Regulation of Gene_expression of Dlg4 10 0.44 2.16 1.85
181 INT14914 Regulation of Cdh5 5 0.52 4.59 1.85
182 INT99416 Negative_regulation of Bcar1 1 0.34 0.64 1.84
183 INT120563 Positive_regulation of Gene_expression of Egfr 56 0.70 46.19 1.82
184 INT77656 Gene_expression of Hsp90aa1 12 0.78 24.27 1.81
185 INT190480 Positive_regulation of Localization of Ros1 11 0.34 8.29 1.81
186 INT43143 Binding of Bad 8 0.21 5.12 1.81
187 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8
188 INT133084 Positive_regulation of Gene_expression of Map2k7 3 0.17 2.56 1.8
189 INT132837 Positive_regulation of Csk 5 0.45 1.75 1.79
190 INT159120 Protein_catabolism of Gnb2l1 1 0.26 0.37 1.79
191 INT124953 Negative_regulation of Gene_expression of Egfr 6 0.42 1.97 1.75
192 INT218303 Protein_catabolism of INSR 3 0.29 0.67 1.73
193 INT232645 Transcription of INSR 2 0.09 1.19 1.71
194 INT23881 Gene_expression of Bcar1 8 0.52 2.48 1.69
195 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68
196 INT75316 Gene_expression of Ghr 6 0.78 1.24 1.68
197 INT117330 Negative_regulation of Binding of ROS1 13 0.37 8.33 1.67
198 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
199 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
200 INT93427 Negative_regulation of Bad 4 0.02 2.5 1.63
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