GO:0019912

From wiki-pain
Jump to: navigation, search
Name cyclin-dependent protein kinase activating kinase activity
Categary Function
Go Slim No
Go Link GO:0019912
Unique Molecular Interactions 71
Total Molecular Interactions 102
Total Single Events 801
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cyclin-dependent protein kinase activating kinase activity. They are ordered first by their pain relevance and then by number of times they were reported for cyclin-dependent protein kinase activating kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
2 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
3 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
4 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
5 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
6 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61
7 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
8 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61
9 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
10 INT319554 Sgk1 Regulation of Cdkn1a 1 0.26 0.09 0.45
11 INT119262 PPM1E Negative_regulation of Positive_regulation of CDKN1A 1 0.01 0.96 0.33
12 INT172977 Cdkn1a Negative_regulation of Positive_regulation of Inca1 1 0.00 1.39 0.27
13 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
14 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
15 INT245555 Runx1 Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
16 INT245565 Runx1 Negative_regulation of Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
17 INT212084 NOXO1 Positive_regulation of CDKN1A 1 0.06 0.53 0.19
18 INT119263 Binding of CDKN1A and PPM1E 1 0.01 0.46 0.17
19 INT123192 Bmp6 Positive_regulation of CDKN1A 1 0.18 0.61 0.14
20 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14
21 INT193789 SDF2L1 Positive_regulation of CDKN1A 1 0.00 0.68 0.13
22 INT193785 SDF2L1 Positive_regulation of Gene_expression of CDKN1A 1 0.00 0.68 0.13
23 INT237922 TNFSF10 Positive_regulation of CDKN1A 1 0.09 3.28 0.08
24 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08
25 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07
26 INT193783 ITIH4 Regulation of Gene_expression of CDKN1A 1 0.03 0.55 0.07
27 INT119268 CDKN1A Regulation of CREBBP 1 0.21 0.44 0.07
28 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
29 INT302160 LAMTOR1 Regulation of CDKN1A 1 0.08 0.26 0.06
30 INT302127 MRPL28 Regulation of CDKN1A 1 0.09 0.26 0.06
31 INT302130 CDKN1A Regulation of CDKN1B 1 0.04 0.26 0.05
32 INT302176 CDKN1C Regulation of CDKN1A 1 0.09 0.26 0.05
33 INT302163 IFI27 Regulation of CDKN1A 1 0.11 0.26 0.05
34 INT176224 Binding of CDKN1A and PCNA 4 0.08 2.52 0.03
35 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03
36 INT303091 Rorb Regulation of CDKN1A 1 0.00 0.52 0.03
37 INT283722 Id2 Negative_regulation of Transcription of CDKN1A 1 0.45 0.11 0.03
38 INT238395 BAX Regulation of CDKN1A 1 0.03 0.31 0.03
39 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03
40 INT223066 CDKN1A Negative_regulation of CCND1 1 0.04 0.66 0.03
41 INT201771 CDKN1A Positive_regulation of Localization of Ccnd1 1 0.04 0 0
42 INT233276 Cdkn1a Regulation of Hoxa10 1 0.12 0.26 0
43 INT182942 VDR Positive_regulation of CDKN1A 1 0.35 0.38 0
44 INT238402 ELANE Positive_regulation of Gene_expression of CDKN1A 1 0.03 0.48 0
45 INT277691 Cdkn1a Negative_regulation of Positive_regulation of Casp3 1 0.00 1.01 0
46 INT225157 CDKN1A Regulation of CHKA 1 0.12 0.58 0
47 INT298197 EGFR Regulation of CDKN1A 1 0.04 1.14 0
48 INT214892 Positive_regulation of HGF Positive_regulation of CDKN1A 1 0.17 0.31 0
49 INT176292 Fasl Regulation of Gene_expression of CDKN1A 1 0.34 0.84 0
50 INT214918 Gtf3a Positive_regulation of CDKN1A 1 0.01 0.66 0
51 INT182912 Binding of CDKN1A and FRA8E 1 0.02 0.37 0
52 INT233274 Tpt1 Regulation of Cdkn1a 1 0.05 0.26 0
53 INT214890 GOPC Positive_regulation of CDKN1A 1 0.06 0.57 0
54 INT325152 CDKN1A Negative_regulation of CCNE2 1 0.07 0.1 0
55 INT301365 Stat1 Positive_regulation of Cdkn1a 1 0.03 0.38 0
56 INT214891 HGF Positive_regulation of CDKN1A 1 0.25 1.15 0
57 INT182935 KCNIP3 Regulation of CDKN1A 1 0.45 0.96 0
58 INT214919 Pkd1 Positive_regulation of CDKN1A 1 0.51 2.6 0
59 INT301364 Stat1 Positive_regulation of Cdkn1a 1 0.03 0.39 0
60 INT182957 CDKN1A Negative_regulation of HNF4A 1 0.02 0.11 0
61 INT214917 Pkd1 Positive_regulation of Negative_regulation of CDKN1A 1 0.37 1.46 0
62 INT238401 PPARA Positive_regulation of Gene_expression of CDKN1A 1 0.11 0.48 0
63 INT182917 Binding of VDR and Positive_regulation of Gene_expression of CDKN1A 1 0.35 0.31 0
64 INT338972 Binding of CDKN1A and TP53 1 0.10 0.98 0
65 INT277694 Cdkn1a Positive_regulation of Positive_regulation of Casp3 1 0.00 1.01 0
66 INT182931 VDR Positive_regulation of Gene_expression of CDKN1A 1 0.48 0.86 0
67 INT182911 KCNIP3 Positive_regulation of CDKN1A 1 0.51 0.35 0
68 INT297966 CDKN1A Positive_regulation of TP53 1 0.08 0.49 0
69 INT176293 Fasl Positive_regulation of Gene_expression of CDKN1A 1 0.35 0.42 0
70 INT182915 Binding of CDKN1A and KCNIP3 1 0.35 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cyclin-dependent protein kinase activating kinase activity. They are ordered first by their pain relevance and then by number of times they were reported in cyclin-dependent protein kinase activating kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
2 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
3 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
4 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
5 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
6 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69
7 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
8 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
9 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26
10 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
11 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
12 INT104331 Negative_regulation of Gene_expression of CDKN1A 24 0.57 13.68 1.63
13 INT146521 Negative_regulation of Positive_regulation of CDKN1A 6 0.42 3.29 0.79
14 INT126732 Regulation of Cdkn1a 6 0.39 2.13 0.63
15 INT97606 Negative_regulation of Cdkn1a 7 0.43 4.24 0.42
16 INT125592 Negative_regulation of Negative_regulation of CDKN1A 2 0.42 2.07 0.41
17 INT117440 Positive_regulation of Cdkn1a 3 0.67 2.95 0.4
18 INT131018 Phosphorylation of Cdkn1a 3 0.61 2.06 0.4
19 INT82797 Transcription of CDKN1A 11 0.69 8.01 0.32
20 INT131017 Positive_regulation of Positive_regulation of Cdkn1a 5 0.67 1.89 0.32
21 INT119269 Binding of CDKN1A 14 0.47 8.82 0.31
22 INT123529 Phosphorylation of CDKN1A 8 0.80 5.69 0.29
23 INT225177 Regulation of Negative_regulation of CDKN1A 1 0.39 0.26 0.25
24 INT245263 Negative_regulation of Gene_expression of Cdkn1a 5 0.25 1.84 0.14
25 INT123181 Positive_regulation of Negative_regulation of CDKN1A 1 0.49 0.6 0.14
26 INT61789 Negative_regulation of Cdkn1a 2 0.41 1.35 0.13
27 INT148991 Gene_expression of Cdkn1a 1 0.44 0.46 0.11
28 INT301361 Phosphorylation of Cdkn1a 2 0.79 1.21 0.09
29 INT346497 Negative_regulation of Phosphorylation of Cdkn1a 1 0.41 0.83 0.09
30 INT328542 Regulation of Positive_regulation of Cdkn1a 1 0.03 0.79 0.07
31 INT176262 Positive_regulation of Phosphorylation of CDKN1A 3 0.49 2.12 0.06
32 INT316430 Positive_regulation of Negative_regulation of Cdkn1a 1 0.19 1.24 0.04
33 INT224295 Protein_catabolism of CDKN1A 1 0.12 0.55 0.03
34 INT172965 Negative_regulation of Positive_regulation of Cdkn1a 4 0.41 1.84 0
35 INT271100 Regulation of Positive_regulation of CDKN1A 2 0.44 1.52 0
36 INT233247 Transcription of Cdkn1a 1 0.39 0.26 0
37 INT277672 Localization of Cdkn1a 1 0.07 0.95 0
38 INT301362 Negative_regulation of Positive_regulation of Cdkn1a 1 0.41 0.39 0
39 INT282083 Regulation of Gene_expression of Cdkn1a 1 0.15 1.25 0
40 INT234750 Regulation of Regulation of CDKN1A 1 0.09 0.45 0
41 INT225184 Positive_regulation of Binding of CDKN1A 1 0.43 0.87 0
42 INT277673 Positive_regulation of Localization of Cdkn1a 1 0.05 1.01 0
43 INT282089 Binding of Cdkn1a 1 0.12 0.36 0
44 INT250716 Positive_regulation of Transcription of CDKN1A 1 0.18 0.48 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox