GO:0019933

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Name cAMP-mediated signaling
Categary Process
Go Slim No
Go Link GO:0019933
Unique Molecular Interactions 524
Total Molecular Interactions 946
Total Single Events 4665
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cAMP-mediated signaling. They are ordered first by their pain relevance and then by number of times they were reported for cAMP-mediated signaling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2
2 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21
3 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71
4 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08
5 INT11248 Gh Positive_regulation of Ghrh 2 0.26 0.09 4.04
6 INT13729 GHRH Positive_regulation of Localization of GH1 13 0.62 0.59 3.2
7 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
8 INT20411 Ghrh Positive_regulation of Gh1 6 0.56 0.62 2.47
9 INT7367 Ghrh Regulation of Localization of Gh1 5 0.49 1.55 2.25
10 INT18197 Ghrh Positive_regulation of Localization of Ggh 4 0.46 0 2.23
11 INT9180 Ghrh Regulation of Localization of Gh 3 0.24 0.25 2.18
12 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
13 INT35502 Ghrh Positive_regulation of Localization of Gnrhr 7 0.57 0.18 2
14 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
15 INT16891 GHRH Regulation of GH1 5 0.37 1.94 1.82
16 INT32482 Ghrh Positive_regulation of Prl 3 0.18 0.26 1.62
17 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
18 INT34834 Ghrh Positive_regulation of Gene_expression of Gh1 2 0.65 0 1.4
19 INT152428 Ghrh Positive_regulation of Pde6b 1 0.07 0.5 1.18
20 INT32480 Gh1 Positive_regulation of Gene_expression of Ghrh 1 0.35 0 1.15
21 INT32182 PRL Regulation of GHRH 2 0.17 0 1.12
22 INT19887 GHRH Positive_regulation of Positive_regulation of GH1 2 0.56 0.3 1.08
23 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08
24 INT5106 Gal Positive_regulation of Localization of Ghrh 1 0.21 0 1.07
25 INT120317 Ghrh Regulation of Positive_regulation of Ngf 1 0.25 0.95 1.06
26 INT120311 Ghrh Regulation of Gene_expression of Ngf 1 0.25 0.95 1.06
27 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
28 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
29 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
30 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
31 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
32 INT35157 GH1 Regulation of GHRH 3 0.17 0.5 0.99
33 INT19758 Ghrh Positive_regulation of Positive_regulation of Gh 1 0.26 0 0.98
34 INT25272 Binding of Ggh and Ghrh 1 0.22 0 0.97
35 INT5108 Gal Positive_regulation of Ghrh 1 0.21 0 0.96
36 INT31108 Ghrh Negative_regulation of Gh1 2 0.55 0 0.95
37 INT295530 Ghrl Regulation of Gene_expression of Ghrh 1 0.30 0.21 0.95
38 INT62106 Ghrh Negative_regulation of Localization of Gh 1 0.06 0 0.94
39 INT35252 Gene_expression of Ghrh Positive_regulation of Localization of Gh1 1 0.49 0 0.93
40 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91
41 INT295547 Ghrl Regulation of Ghrh 1 0.30 0.06 0.9
42 INT30411 Ghrh Regulation of Gene_expression of Gh1 1 0.40 0.12 0.9
43 INT62111 SLC25A4 Negative_regulation of Regulation of Ghrh 1 0.41 0 0.9
44 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
45 INT15730 Ghrh Positive_regulation of Gnrhr 2 0.14 0.08 0.84
46 INT115655 Glp1r Positive_regulation of Ins1 1 0.42 0 0.84
47 INT84102 B3GAT1 Positive_regulation of Localization of Glp1r 1 0.09 0 0.83
48 INT346133 RAMP2 Regulation of ADM 1 0.13 2.06 0.78
49 INT33995 Ghrh Regulation of Gnrhr 2 0.18 0.43 0.77
50 INT305034 Adcy8 Regulation of Localization of Adcy1 1 0.35 1.51 0.77
51 INT305033 Adcy1 Regulation of Localization of Adcy8 1 0.35 1.51 0.77
52 INT190788 Adcy8 Positive_regulation of Adcy1 1 0.23 0.77 0.77
53 INT18402 Glp1r Regulation of Localization of Sst 1 0.19 0 0.77
54 INT152429 Ghrh Positive_regulation of Localization of Gh 4 0.37 0.56 0.75
55 INT31306 Ghrh Regulation of Localization of Gnrhr 2 0.14 1 0.73
56 INT16894 Regulation of GHRH Regulation of GH1 2 0.37 0 0.72
57 INT31307 Ghrh Regulation of Gh1 3 0.27 1.36 0.7
58 INT30125 Binding of Gh and Ghrh 2 0.06 0.36 0.7
59 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
60 INT64070 Tp63 Regulation of Ghrh 1 0.04 0.06 0.69
61 INT40470 GH1 Positive_regulation of GHRH 1 0.06 0 0.67
62 INT5105 Gal Regulation of Localization of Ghrh 1 0.19 0 0.66
63 INT190211 Adm Regulation of MMP12 1 0.29 0 0.65
64 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
65 INT62249 Ghrh Regulation of Adrb1 1 0.00 0 0.62
66 INT19011 Binding of Ghrh and Ghsr 1 0.40 0 0.62
67 INT61507 Ghrhr Positive_regulation of Localization of Gh1 1 0.41 0 0.61
68 INT18405 GHRH Positive_regulation of Regulation of SST 1 0.56 0 0.57
69 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
70 INT32484 Gnrhr Regulation of GHRH 1 0.01 0 0.55
71 INT69566 Positive_regulation of Ghrh Regulation of Gh 1 0.04 1.66 0.55
72 INT32478 Gh1 Regulation of Gene_expression of Ghrh 1 0.28 0 0.55
73 INT141371 Positive_regulation of CREM Negative_regulation of Crem 1 0.00 0 0.54
74 INT108441 Adm Positive_regulation of Sst 1 0.40 0 0.54
75 INT30959 Ghrh Positive_regulation of Localization of SST 1 0.01 0 0.54
76 INT34368 TRH Positive_regulation of GHRH 1 0.23 0.4 0.53
77 INT141372 CREM Negative_regulation of Crem 1 0.00 0 0.53
78 INT346146 ADM Positive_regulation of Gene_expression of PERP 1 0.02 1.54 0.51
79 INT56671 Negative_regulation of Ghrh Positive_regulation of Gh1 1 0.40 0 0.49
80 INT67984 GHRH Regulation of PRL 1 0.22 0 0.49
81 INT48114 GHRH Positive_regulation of Localization of CGB 1 0.05 0 0.48
82 INT34988 Ghrh Positive_regulation of Calca 1 0.06 0 0.48
83 INT67983 Positive_regulation of HTR1B Positive_regulation of Localization of GHRH 1 0.42 0 0.47
84 INT34990 Calca Positive_regulation of Ghrh 1 0.06 0 0.47
85 INT141964 Binding of ADM and RAMP1 1 0.30 2.63 0.47
86 INT101001 GHRH Regulation of Localization of INS 1 0.28 0 0.47
87 INT101003 GHRH Regulation of Localization of GGH 1 0.29 0 0.47
88 INT108440 Adm Regulation of Localization of Sst 1 0.41 0 0.45
89 INT295548 Ghrl Regulation of Regulation of Ghrh 1 0.30 0 0.45
90 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43
91 INT152430 Regulation of Ghrh Positive_regulation of Pde6b 1 0.04 0.16 0.43
92 INT275087 Pde2a Negative_regulation of stm 1 0.01 0.51 0.42
93 INT48038 Adm Regulation of Calca 1 0.31 0.14 0.42
94 INT275104 Pde2a Negative_regulation of RTP3 1 0.00 0.51 0.42
95 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41
96 INT250531 Ghrh Regulation of Gh 1 0.22 0 0.41
97 INT59742 Glp1r Positive_regulation of Gene_expression of Npy 1 0.27 0.32 0.41
98 INT346151 Binding of ADM and GPER 1 0.01 0.99 0.41
99 INT59740 Glp1r Positive_regulation of Localization of Npy 1 0.25 0.33 0.41
100 INT59739 Glp1r Positive_regulation of Transcription of Npy 1 0.25 0.32 0.41
101 INT16302 GHRH Regulation of Localization of GH1 1 0.65 0.62 0.4
102 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
103 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
104 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
105 INT62107 Ghrh Negative_regulation of Regulation of Gh 1 0.06 0 0.39
106 INT346150 Binding of ADM and FN1 1 0.10 0.93 0.39
107 INT346140 Positive_regulation of Binding of ADM and MMRN1 1 0.04 0.93 0.39
108 INT346139 Binding of ADM and MMRN1 1 0.03 0.93 0.39
109 INT346135 Positive_regulation of Binding of ADM and FN1 1 0.13 0.93 0.39
110 INT67553 Ghrh Positive_regulation of Regulation of Gh 1 0.04 0.55 0.39
111 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
112 INT152431 Regulation of Ghrh Positive_regulation of Scn7a 1 0.02 0.17 0.38
113 INT152426 Ghrh Positive_regulation of Positive_regulation of Pde6b 1 0.07 0.14 0.38
114 INT55427 Grpr Positive_regulation of Localization of Glp1r 1 0.02 0 0.38
115 INT152427 Ghrh Positive_regulation of Scn7a 1 0.03 0.17 0.38
116 INT8331 OPRD1 Regulation of Localization of GHRH 1 0.18 0.18 0.37
117 INT34865 Ghrh Positive_regulation of Gene_expression of Gnrhr 1 0.07 0 0.37
118 INT35363 Binding of GH1 and GHRH 2 0.36 0.94 0.36
119 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
120 INT130974 Slc9a3r1 Positive_regulation of ASIC3 1 0.08 0.29 0.36
121 INT346145 Binding of ADM and TPX2 1 0.01 1.05 0.35
122 INT84030 Regulation of Ghrh Positive_regulation of Gh 1 0.18 0 0.35
123 INT54930 Gnrhr Regulation of Gene_expression of Ghrh 1 0.10 0.16 0.34
124 INT55426 Sct Positive_regulation of Localization of Glp1r 1 0.49 0 0.33
125 INT295539 Gabrg1 Positive_regulation of Gene_expression of Ghrh 1 0.30 0 0.33
126 INT31042 Ghrh Positive_regulation of Localization of PLOD1 1 0.08 0 0.32
127 INT311228 DPP4 Negative_regulation of Localization of GLP1R 1 0.31 1.25 0.32
128 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
129 INT31040 Ghrh Positive_regulation of Localization of FSHR 1 0.05 0 0.31
130 INT31043 Ghrh Positive_regulation of PLOD1 1 0.03 0 0.31
131 INT55429 Binding of Gip and Glp1r 1 0.39 0 0.31
132 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31
133 INT31041 Ghrh Positive_regulation of FSHR 1 0.05 0 0.31
134 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
135 INT26065 GHRH Regulation of Regulation of GH1 1 0.11 0 0.3
136 INT226989 Lias Regulation of Gene_expression of Lep 1 0.10 0.91 0.3
137 INT55425 Gip Positive_regulation of Localization of Glp1r 1 0.44 0 0.3
138 INT31036 Ghrh Regulation of Gnrh1 1 0.19 0 0.29
139 INT25169 GHRH Positive_regulation of Localization of Gh 1 0.12 0 0.29
140 INT60181 Binding of HTR5A and Pik3c3 1 0.03 0.1 0.29
141 INT43837 POMC Positive_regulation of GHRH 1 0.16 0 0.28
142 INT43836 Regulation of POMC Positive_regulation of GHRH 1 0.14 0 0.28
143 INT89910 GHRH Positive_regulation of Localization of POMC 1 0.33 0 0.28
144 INT89896 GHRH Positive_regulation of Localization of PRL 1 0.30 0 0.27
145 INT295531 Ghrl Negative_regulation of Gene_expression of Ghrh 1 0.25 0 0.27
146 INT20029 Ghrh Positive_regulation of Negative_regulation of Gh 1 0.05 0.14 0.26
147 INT295541 Ghrl Positive_regulation of Ghrh 1 0.31 0 0.26
148 INT68872 Ghrh Regulation of IGF1 1 0.09 0.18 0.26
149 INT295535 Gabrg1 Regulation of Ghrh 1 0.16 0.08 0.26
150 INT100531 Cck Positive_regulation of Lep 1 0.70 0.15 0.26
151 INT83220 Gucy1a2 Positive_regulation of Positive_regulation of Glp1r 1 0.02 0 0.26
152 INT78780 Binding of Calca and Adm 1 0.32 0.07 0.26
153 INT34784 DIO2 Regulation of Localization of GHRH 1 0.00 0 0.25
154 INT74043 Negative_regulation of Oprd1 Negative_regulation of Localization of GHRH 1 0.02 0 0.25
155 INT34785 DIO2 Positive_regulation of Localization of GHRH 1 0.01 0 0.25
156 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
157 INT74044 GHRH Positive_regulation of Localization of Oprd1 1 0.02 0 0.25
158 INT250536 Ghrh Positive_regulation of Negative_regulation of Ptpn6 1 0.09 0 0.24
159 INT32330 POMC Positive_regulation of Localization of GHRH 1 0.12 0 0.24
160 INT50488 Vip Positive_regulation of Localization of Ghrh 1 0.60 0 0.24
161 INT71091 ADCYAP1 Positive_regulation of Localization of GHRH 1 0.26 0.26 0.24
162 INT85011 ADM Regulation of CALCRL 1 0.06 0 0.24
163 INT71090 ADCYAP1 Positive_regulation of GHRH 1 0.12 0.26 0.24
164 INT215037 Ghrh Regulation of Localization of Igf2 1 0.04 2.12 0.24
165 INT235125 PDE2A Negative_regulation of Twist1 1 0.00 0.99 0.24
166 INT20030 Negative_regulation of SST Positive_regulation of Ghrh 1 0.01 0.16 0.23
167 INT346134 ADM Regulation of Gene_expression of MMRN1 1 0.04 1.29 0.23
168 INT78782 Binding of Adm and Adm 1 0.01 0.07 0.23
169 INT346143 ADM Regulation of Gene_expression of TPX2 1 0.02 1.29 0.23
170 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22
171 INT110653 Lep Regulation of Localization of Cck 1 0.06 0.22 0.22
172 INT58243 Ghrh Regulation of Prl 1 0.04 0.18 0.21
173 INT35149 PLOD1 Regulation of GHRH 1 0.02 0 0.21
174 INT32325 DBI Positive_regulation of GHRH 1 0.02 0 0.21
175 INT35153 FSHR Regulation of GHRH 1 0.04 0 0.21
176 INT32331 DBI Positive_regulation of Localization of GHRH 1 0.02 0 0.21
177 INT257398 Binding of FGD1 and GHRH 1 0.03 0.27 0.2
178 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2
179 INT30071 Gm8212 Regulation of Pde3a 1 0.00 0 0.2
180 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19
181 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19
182 INT273048 Adcyap1 Positive_regulation of Adcyap1r1 1 0.11 1.02 0.19
183 INT268797 Ghrh Positive_regulation of Transcription of Gh 1 0.20 0.33 0.19
184 INT295542 Ghrl Positive_regulation of Gene_expression of Ghrh 1 0.33 0 0.19
185 INT172254 Binding of ADM and TAS2R14 1 0.02 0 0.17
186 INT226988 Lias Positive_regulation of Localization of Lep 1 0.08 0.3 0.17
187 INT256987 Binding of Cd81 and Slc9a3r1 1 0.43 0.06 0.17
188 INT125770 GLP1R Negative_regulation of Localization of GCG 2 0.29 0.65 0.16
189 INT311226 DPP4 Negative_regulation of GLP1R 1 0.31 0.65 0.16
190 INT295543 Ghrh Regulation of Gene_expression of Npy 1 0.36 0 0.16
191 INT222509 Ghrh Positive_regulation of Localization of Prl 1 0.28 0.23 0.16
192 INT59744 Glp1r Regulation of Localization of Ins1 1 0.07 0.14 0.16
193 INT295536 Ghrh Regulation of Npy 1 0.22 0 0.16
194 INT349850 Gfra1 Negative_regulation of Adcyap1r1 1 0.15 0.36 0.15
195 INT263179 PDE3A Regulation of COPD 1 0.00 1 0.15
196 INT250533 Ghrh Regulation of Localization of Gh 1 0.13 0 0.15
197 INT349851 Gfra3 Negative_regulation of Adcyap1r1 1 0.28 0.31 0.15
198 INT263178 Binding of PDE7A and COPD 1 0.01 1 0.15
199 INT263177 Binding of PDE3A and COPD 1 0.01 1 0.15
200 INT349849 Gfra2 Negative_regulation of Adcyap1r1 1 0.33 0.31 0.15

Single Events

The table below shows the top 100 pain related interactions that have been reported for cAMP-mediated signaling. They are ordered first by their pain relevance and then by number of times they were reported in cAMP-mediated signaling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5095 Localization of Ghrh 185 0.81 28.09 62.08
2 INT249 Localization of GHRH 215 0.80 78.02 51.87
3 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52
4 INT5100 Positive_regulation of Ghrh 100 0.64 24.2 30.21
5 INT18400 Localization of Glp1r 97 0.80 11.96 24.32
6 INT250 Regulation of GHRH 65 0.61 17.46 23.19
7 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
8 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74
9 INT7364 Regulation of Ghrh 49 0.58 8.05 19.05
10 INT9179 Positive_regulation of Localization of Ghrh 42 0.70 7.05 18.1
11 INT984 Positive_regulation of Localization of GHRH 58 0.70 12.66 16.51
12 INT7366 Negative_regulation of Ghrh 42 0.58 7.72 14.45
13 INT16530 Gene_expression of Ghrh 45 0.77 6.22 13.44
14 INT73641 Regulation of Lep 45 0.62 26.2 12.59
15 INT254 Regulation of Localization of GHRH 30 0.60 5.17 11.46
16 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
17 INT19010 Negative_regulation of Localization of Ghrh 27 0.57 4.85 10.5
18 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34
19 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
20 INT55038 Gene_expression of Adcy8 10 0.77 28.79 9.8
21 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
22 INT82082 Localization of Lep 63 0.81 26.41 8.56
23 INT953 Positive_regulation of Positive_regulation of GHRH 17 0.67 2.38 8.18
24 INT186142 Gene_expression of Ghrh 45 0.66 34.04 6.94
25 INT47944 Positive_regulation of Localization of Glp1r 23 0.70 0.16 6.79
26 INT7925 Transcription of Ghrh 13 0.67 2.36 6.77
27 INT47942 Positive_regulation of Glp1r 38 0.70 15.94 6.47
28 INT72110 Gene_expression of Glp1r 48 0.78 22.46 6.17
29 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13
30 INT74208 Positive_regulation of Crem 14 0.69 2.49 5.98
31 INT7361 Binding of Ghrh 13 0.45 1.37 5.44
32 INT55037 Positive_regulation of Adcy8 7 0.61 5.92 5.36
33 INT188852 Gene_expression of Pde2a 13 0.19 6.44 5.35
34 INT9178 Regulation of Localization of Ghrh 13 0.45 2.28 5.08
35 INT19900 Binding of GHRH 22 0.37 5.75 5
36 INT121471 Negative_regulation of Pde3a 24 0.34 13.79 4.73
37 INT63651 Gene_expression of Adcyap1r1 17 0.77 2.57 4.58
38 INT19008 Positive_regulation of Positive_regulation of Ghrh 15 0.49 2.4 4.55
39 INT97391 Binding of Lep 18 0.48 8.97 4.47
40 INT37379 Regulation of Localization of Glp1r 10 0.62 0.16 4.32
41 INT16304 Negative_regulation of Positive_regulation of GHRH 9 0.51 2.56 4.25
42 INT70756 Gene_expression of Adm 28 0.77 13.33 4.22
43 INT142059 Regulation of Ghrh 15 0.59 3.25 3.94
44 INT74205 Gene_expression of Crem 6 0.77 5.31 3.93
45 INT74206 Positive_regulation of Gene_expression of Crem 6 0.69 3.3 3.85
46 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
47 INT986 Negative_regulation of Localization of GHRH 16 0.58 8.57 3.16
48 INT75815 Positive_regulation of PDE2A 10 0.40 5.1 3.15
49 INT18399 Regulation of Glp1r 11 0.53 3.78 2.97
50 INT30172 Positive_regulation of Pde2a 3 0.39 0.55 2.77
51 INT305030 Localization of Adcy8 2 0.75 8.18 2.63
52 INT215029 Negative_regulation of Ghrh 15 0.56 11.37 2.62
53 INT20028 Positive_regulation of Gene_expression of Ghrh 9 0.50 1.52 2.62
54 INT55036 Regulation of Adcy8 3 0.44 0.85 2.56
55 INT55039 Positive_regulation of Gene_expression of Adcy8 3 0.69 6.64 2.39
56 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
57 INT115654 Localization of Glp1r 11 0.75 3.79 2.34
58 INT72109 Negative_regulation of Localization of Glp1r 8 0.59 0.8 2.3
59 INT250727 Negative_regulation of ADM 3 0.38 8.32 2.26
60 INT16527 Negative_regulation of Positive_regulation of Ghrh 6 0.43 1.01 2.23
61 INT27269 Localization of Ghrh 29 0.76 15.42 2.19
62 INT263127 Negative_regulation of PDE7A 13 0.27 8.03 2.13
63 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
64 INT11604 Regulation of Positive_regulation of Ghrh 4 0.42 0.62 2.05
65 INT83392 Transcription of Lep 6 0.54 5.07 2.04
66 INT54929 Negative_regulation of Transcription of Ghrh 4 0.43 0.69 2.04
67 INT16529 Negative_regulation of Gene_expression of Ghrh 6 0.43 0.34 2.02
68 INT59737 Negative_regulation of Glp1r 15 0.43 6.94 2.01
69 INT141968 Positive_regulation of ADM 12 0.65 11.19 2
70 INT190782 Negative_regulation of Adcy8 3 0.58 4.37 1.84
71 INT142060 Positive_regulation of Ghrh 15 0.66 7.21 1.83
72 INT64530 Negative_regulation of Positive_regulation of Pde2a 1 0.36 0 1.81
73 INT119905 Negative_regulation of PDE3A 5 0.18 5 1.77
74 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
75 INT102449 Binding of ADM 12 0.33 5.85 1.73
76 INT77415 Localization of GLP1R 23 0.63 11.1 1.69
77 INT12781 Regulation of Pde2a 4 0.23 1.14 1.69
78 INT954 Positive_regulation of Gene_expression of GHRH 18 0.50 7.6 1.63
79 INT64529 Localization of Pde2a 1 0.59 0 1.63
80 INT114163 Regulation of HTR5A 2 0.27 0.2 1.61
81 INT1580 Negative_regulation of Pde2a 7 0.52 3.26 1.59
82 INT188855 Positive_regulation of Gene_expression of Pde2a 5 0.12 1.97 1.53
83 INT242212 Gene_expression of GLP1R 29 0.65 11.36 1.52
84 INT43264 Transcription of GHRH 5 0.59 0.4 1.42
85 INT102228 Localization of Adm 9 0.69 1.58 1.34
86 INT47102 Regulation of Binding of GHRH 2 0.28 0 1.34
87 INT14195 Localization of Pde2a 4 0.16 0.34 1.33
88 INT169743 Regulation of Positive_regulation of Adm 1 0.37 0.38 1.32
89 INT58421 Positive_regulation of Transcription of GHRH 1 0.43 0.38 1.32
90 INT252389 Negative_regulation of Gene_expression of ADM 2 0.38 4.78 1.3
91 INT264798 Binding of GLP1R 9 0.40 2.95 1.27
92 INT8334 Regulation of Positive_regulation of GHRH 3 0.43 0.7 1.27
93 INT105908 Gene_expression of PDE7A 21 0.78 4.49 1.26
94 INT48037 Regulation of Adm 8 0.44 3.96 1.24
95 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2
96 INT141969 Positive_regulation of Gene_expression of ADM 4 0.57 4.07 1.2
97 INT145960 Positive_regulation of GLP1R 19 0.58 7.25 1.19
98 INT81757 Regulation of Gene_expression of Adm 6 0.44 2.86 1.16
99 INT25432 Negative_regulation of Gene_expression of GHRH 6 0.37 2.9 1.12
100 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
101 INT144326 Regulation of Gene_expression of Crem 1 0.58 0.15 1.02
102 INT7834 Gene_expression of Pde2a 5 0.51 1.9 1.01
103 INT240800 Positive_regulation of Gene_expression of Glp1r 1 0.44 2.01 1.01
104 INT246720 Gene_expression of Glp1r 9 0.63 6.53 0.96
105 INT188851 Regulation of Gene_expression of Pde2a 1 0.04 0.75 0.94
106 INT13732 Negative_regulation of Regulation of GHRH 3 0.43 0.84 0.93
107 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92
108 INT225094 Localization of ADM 5 0.63 3.89 0.91
109 INT55422 Binding of Glp1r 7 0.48 3.35 0.9
110 INT119118 Transcription of Crem 1 0.58 0 0.89
111 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
112 INT6966 Negative_regulation of Htr5a 2 0.48 0.07 0.85
113 INT121472 Positive_regulation of Glp1r 10 0.65 7.85 0.84
114 INT71970 Positive_regulation of Adcyap1r1 6 0.14 0.49 0.84
115 INT305028 Positive_regulation of Positive_regulation of Adcy8 1 0.44 1.56 0.82
116 INT89776 Positive_regulation of Pde2a 2 0.47 2.84 0.81
117 INT145306 Gene_expression of Sox9 5 0.54 2.47 0.8
118 INT98275 Negative_regulation of PDE2A 4 0.17 3.96 0.79
119 INT52373 Positive_regulation of Adcyap1r1 1 0.00 0.3 0.78
120 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
121 INT18406 Regulation of Regulation of GHRH 2 0.45 0.93 0.76
122 INT34944 Protein_catabolism of Ghrh 1 0.73 0 0.76
123 INT177533 Negative_regulation of Binding of Pde3a 1 0.21 2.46 0.76
124 INT34943 Positive_regulation of Protein_catabolism of Ghrh 1 0.41 0 0.76
125 INT19891 Regulation of Gene_expression of GHRH 3 0.43 1.46 0.68
126 INT29460 Regulation of Gene_expression of Ghrh 3 0.31 0.3 0.68
127 INT115653 Regulation of Glp1r 2 0.60 1.09 0.67
128 INT183161 Regulation of Pde2a 2 0.05 0.5 0.67
129 INT64981 Regulation of Transcription of Ghrh 1 0.26 0.88 0.67
130 INT215025 Negative_regulation of Gene_expression of Ghrh 10 0.41 7.8 0.65
131 INT162911 Gene_expression of PDE3A 2 0.24 2.47 0.65
132 INT101674 Regulation of Regulation of Ghrh 1 0.38 0 0.65
133 INT116247 Positive_regulation of Localization of Adm 1 0.04 0.17 0.62
134 INT242210 Positive_regulation of Gene_expression of GLP1R 6 0.58 3.59 0.61
135 INT145957 Positive_regulation of Localization of GLP1R 5 0.43 2.12 0.61
136 INT61506 Localization of Ghrhr 1 0.51 0 0.61
137 INT83391 Negative_regulation of Transcription of Lep 1 0.43 0.34 0.6
138 INT190734 Transcription of Adcyap1r1 1 0.19 0.1 0.6
139 INT47943 Positive_regulation of Positive_regulation of Glp1r 5 0.70 1.38 0.59
140 INT130971 Binding of Slc9a3r1 2 0.39 0.32 0.59
141 INT264800 Positive_regulation of Binding of GLP1R 1 0.07 0.17 0.59
142 INT184222 Negative_regulation of SOX9 7 0.41 2.68 0.58
143 INT157103 Transcription of SOX9 6 0.59 1.2 0.58
144 INT75814 Regulation of Positive_regulation of PDE2A 1 0.23 0.26 0.56
145 INT74101 Negative_regulation of Adm 3 0.06 1.2 0.53
146 INT157104 Positive_regulation of SOX9 6 0.66 1.66 0.52
147 INT346181 Regulation of Gene_expression of ADM 1 0.35 1.67 0.52
148 INT157105 Positive_regulation of Transcription of SOX9 4 0.58 0.88 0.51
149 INT62836 Binding of HTR5A 1 0.47 0 0.49
150 INT133228 Protein_catabolism of Glp1r 8 0.88 2.65 0.48
151 INT56670 Positive_regulation of Negative_regulation of Ghrh 2 0.49 0.12 0.48
152 INT69423 Positive_regulation of Regulation of Ghrh 1 0.50 0 0.48
153 INT250506 Negative_regulation of Positive_regulation of Ghrh 2 0.41 0.14 0.47
154 INT74207 Positive_regulation of Positive_regulation of Crem 1 0.46 0.26 0.47
155 INT116387 Binding of Adm 6 0.47 1 0.46
156 INT145304 Regulation of Gene_expression of Sox9 1 0.43 1.04 0.46
157 INT311230 Regulation of GLP1R 6 0.38 3.2 0.45
158 INT162903 Localization of PDE2A 2 0.61 0.89 0.45
159 INT58420 Negative_regulation of Transcription of GHRH 1 0.37 0.13 0.45
160 INT121469 Binding of Pde3a 2 0.23 1.42 0.44
161 INT216759 Binding of PDE2A 1 0.00 0.08 0.44
162 INT71561 Positive_regulation of Gene_expression of Adm 4 0.61 2.67 0.43
163 INT186141 Regulation of Gene_expression of Ghrh 2 0.29 0.87 0.43
164 INT336707 Negative_regulation of Gene_expression of Adcy8 1 0.58 3.17 0.43
165 INT130969 Positive_regulation of Binding of Slc9a3r1 1 0.09 0.26 0.43
166 INT207726 Regulation of ADM 4 0.40 2.14 0.42
167 INT64130 Localization of Crem 2 0.51 0.64 0.42
168 INT246675 Negative_regulation of Glp1r 5 0.55 6.01 0.41
169 INT2018 Regulation of Adcyap1r1 2 0.44 0.3 0.4
170 INT105906 Transcription of PDE7A 8 0.72 1.21 0.39
171 INT275542 Regulation of Gene_expression of PDE7A 1 0.12 1.98 0.39
172 INT346173 Negative_regulation of Positive_regulation of ADM 1 0.38 1.02 0.39
173 INT275538 Regulation of PDE7A 1 0.12 1.97 0.39
174 INT36781 Binding of Pclo 1 0.23 0 0.39
175 INT332612 Protein_catabolism of Glp1r 1 0.18 3.56 0.38
176 INT130972 Gene_expression of Slc9a3r1 2 0.63 0.36 0.37
177 INT138356 Positive_regulation of Regulation of Glp1r 1 0.12 0.45 0.35
178 INT235122 Negative_regulation of Positive_regulation of PDE2A 1 0.01 0.72 0.35
179 INT235113 Positive_regulation of Negative_regulation of PDE2A 1 0.01 0.72 0.35
180 INT135945 Positive_regulation of Positive_regulation of PDE2A 2 0.12 0.78 0.34
181 INT129741 Regulation of Crem 1 0.00 0.34 0.34
182 INT7360 Regulation of Binding of Ghrh 1 0.45 0.18 0.33
183 INT60179 Negative_regulation of Localization of HTR5A 1 0.41 0 0.33
184 INT219588 Negative_regulation of Gene_expression of Pde3a 1 0.25 0 0.32
185 INT190725 Regulation of Gene_expression of Adcyap1r1 1 0.13 0 0.32
186 INT219563 Gene_expression of Pde3a 1 0.39 0 0.32
187 INT240798 Regulation of Gene_expression of Glp1r 1 0.39 0.58 0.31
188 INT242207 Negative_regulation of Localization of GLP1R 3 0.36 2.82 0.3
189 INT215024 Positive_regulation of Negative_regulation of Ghrh 2 0.44 1.54 0.3
190 INT60180 Localization of HTR5A 1 0.73 0 0.3
191 INT187005 Positive_regulation of Gene_expression of Ghrh 9 0.48 8.02 0.29
192 INT115287 Negative_regulation of HTR5A 1 0.22 0.41 0.28
193 INT72536 Phosphorylation of Ghrh 1 0.63 0 0.27
194 INT16219 Negative_regulation of Regulation of Ghrh 1 0.11 0.5 0.27
195 INT242211 Negative_regulation of GLP1R 9 0.36 3.4 0.26
196 INT63649 Positive_regulation of Gene_expression of Adcyap1r1 1 0.03 0.1 0.26
197 INT2017 Negative_regulation of Regulation of Adcyap1r1 1 0.41 0 0.25
198 INT250511 Binding of Ghrh 2 0.35 0 0.24
199 INT240801 Negative_regulation of Gene_expression of Glp1r 2 0.37 1.34 0.24
200 INT263139 Positive_regulation of Negative_regulation of PDE7A 1 0.23 0.65 0.24
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