GO:0020027

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Name hemoglobin metabolic process
Categary Process
Go Slim No
Go Link GO:0020027
Unique Molecular Interactions 69
Total Molecular Interactions 97
Total Single Events 1589
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hemoglobin metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for hemoglobin metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT42580 CAT Negative_regulation of POMC 1 0.20 0.42 1.26
2 INT56990 Cat Regulation of Efs 1 0.26 0 1.05
3 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
4 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
5 INT168457 Sult1a1 Positive_regulation of Cat 1 0.15 1.56 0.78
6 INT56459 ADRA2C Positive_regulation of Localization of AHSP 1 0.23 0 0.78
7 INT33575 ADRB1 Positive_regulation of Localization of Ahsp 1 0.00 0.33 0.73
8 INT241912 Cat Positive_regulation of Ros1 1 0.03 0.76 0.44
9 INT255803 Cat Negative_regulation of Gene_expression of Il6 1 0.05 0.35 0.35
10 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31
11 INT241911 Binding of Cat and Ros1 1 0.03 0.85 0.27
12 INT148629 Binding of Cat and Casp3 1 0.08 0.09 0.26
13 INT120583 Gsta4 Regulation of Cat 1 0.03 0 0.23
14 INT333394 CFD Negative_regulation of Gene_expression of Cat 1 0.03 0.79 0.22
15 INT334379 Ros1 Regulation of Cat 1 0.04 0.08 0.21
16 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17
17 INT29959 Ahsp Positive_regulation of Npr1 1 0.00 0.18 0.17
18 INT241177 Abl2 Regulation of Cat 1 0.14 0.3 0.15
19 INT17014 AHSP Positive_regulation of Positive_regulation of RTCA 1 0.07 1.11 0.14
20 INT211921 Gene_expression of Nek1 Positive_regulation of Cat 1 0.01 0.26 0.1
21 INT186246 Binding of CAT and SCN5A 1 0.03 0.47 0.1
22 INT186245 Binding of AGRP and CAT 1 0.02 0.53 0.1
23 INT241913 AAVS1 Positive_regulation of Cat 1 0.04 0.46 0.1
24 INT23896 Positive_regulation of Rtcd1 Positive_regulation of Cat 1 0.25 0 0.08
25 INT166919 Binding of CAT and GSTK1 1 0.09 0.16 0.07
26 INT227353 Binding of Cat and Mpo 1 0.18 0.56 0.07
27 INT281879 Cat Negative_regulation of Fig4 1 0.01 0.96 0.06
28 INT229419 Atp6v0a2 Regulation of Cat 1 0.01 1.73 0.06
29 INT266901 Nfe2l2 Positive_regulation of Cat 1 0.10 0.19 0.04
30 INT227352 Binding of Cat and Ros1 1 0.04 1.06 0.04
31 INT252767 CAT Regulation of Gpx1 1 0.00 0.25 0.04
32 INT292416 SOD1 Regulation of Cat 1 0.01 0.45 0.03
33 INT311144 CAT Positive_regulation of APRT 1 0.01 0 0.03
34 INT338838 Binding of Cat and Tnnc1 1 0.03 1.77 0
35 INT285403 Binding of CAT and MPO 1 0.30 0.9 0
36 INT181697 Positive_regulation of Ldha Negative_regulation of Cat 1 0.29 0.6 0
37 INT311145 CAT Positive_regulation of Protein_catabolism of APRT 1 0.01 0 0
38 INT149115 Cat Negative_regulation of Pax3 1 0.02 0.05 0
39 INT155123 Binding of Gpx1 and Cat 1 0.04 0.05 0
40 INT206959 Lipg Regulation of Cat 1 0.02 0.5 0
41 INT287885 Binding of DVL1 and AXIN1 1 0.02 0 0
42 INT338839 Negative_regulation of Binding of Cat and Tnnc1 1 0.04 1.78 0
43 INT239182 Gene_expression of Gh Negative_regulation of Cat 1 0.17 0.33 0
44 INT236724 Binding of AXIN1 and Ctnnd2 1 0.39 1.03 0
45 INT155124 Positive_regulation of Binding of Gpx1 and Cat 1 0.05 0.05 0
46 INT181696 Ldha Negative_regulation of Cat 1 0.27 1.16 0
47 INT341409 Ccl4 Regulation of Cat 1 0.25 0.07 0
48 INT89807 Binding of Cat and Penk 1 0.21 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hemoglobin metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in hemoglobin metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84
2 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61
3 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04
4 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76
5 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67
6 INT79720 Positive_regulation of Cat 57 0.70 31.81 10.11
7 INT120509 Gene_expression of Cat 65 0.77 50.9 9.75
8 INT6125 Localization of Ahsp 35 0.78 9.17 9.42
9 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18
10 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38
11 INT38366 Regulation of Cat 45 0.62 23.45 5.34
12 INT120511 Positive_regulation of Gene_expression of Cat 26 0.69 19.82 5.2
13 INT17020 Localization of AHSP 11 0.80 3.82 4.34
14 INT6126 Gene_expression of Ahsp 16 0.67 7.72 4.08
15 INT12948 Positive_regulation of Gene_expression of Cat 17 0.67 6.46 3.12
16 INT12410 Negative_regulation of Ahsp 10 0.29 3.49 3.07
17 INT79722 Regulation of Cat 14 0.62 5.88 2.86
18 INT113892 Binding of Cat 6 0.48 3.95 2.65
19 INT22129 Positive_regulation of Gene_expression of CAT 11 0.67 4.23 2.37
20 INT123873 Positive_regulation of Negative_regulation of Cat 7 0.50 2.86 1.86
21 INT19265 Negative_regulation of Localization of AHSP 3 0.59 0.62 1.69
22 INT163666 Localization of Cat 8 0.80 5.84 1.57
23 INT21950 Positive_regulation of Localization of Ahsp 5 0.44 0.81 1.28
24 INT91122 Localization of CAT 6 0.78 4.13 1.19
25 INT148228 Positive_regulation of Regulation of Cat 1 0.49 1.16 1.19
26 INT12952 Negative_regulation of Gene_expression of Cat 16 0.57 7.44 1.14
27 INT125356 Negative_regulation of Negative_regulation of Cat 4 0.42 2.66 1.06
28 INT17627 Binding of Ahsp 3 0.25 1.83 1.04
29 INT8231 Positive_regulation of Gene_expression of Ahsp 2 0.04 1.16 1
30 INT12945 Negative_regulation of Positive_regulation of Cat 3 0.41 2.61 0.97
31 INT53682 Regulation of Gene_expression of CAT 2 0.60 0.36 0.96
32 INT55052 Binding of Cat 10 0.36 5.46 0.92
33 INT66314 Negative_regulation of Positive_regulation of CAT 4 0.42 0.8 0.91
34 INT142919 Regulation of Gene_expression of Cat 2 0.32 0.33 0.89
35 INT93747 Localization of Cat 9 0.56 4.25 0.88
36 INT130188 Positive_regulation of Negative_regulation of Cat 5 0.45 2.26 0.86
37 INT19154 Negative_regulation of Localization of Ahsp 4 0.22 2.07 0.73
38 INT17021 Negative_regulation of AHSP 5 0.43 3.45 0.72
39 INT89801 Positive_regulation of Positive_regulation of Cat 2 0.49 0.21 0.71
40 INT17018 Positive_regulation of Localization of AHSP 3 0.70 0.6 0.66
41 INT107417 Regulation of CAT 8 0.60 2.4 0.61
42 INT266893 Negative_regulation of Gene_expression of Cat 4 0.58 3.76 0.55
43 INT130387 Binding of CAT 4 0.36 2.39 0.55
44 INT15294 Regulation of Ahsp 2 0.37 0.65 0.5
45 INT17019 Positive_regulation of AHSP 3 0.70 1.85 0.49
46 INT210125 Regulation of Axin1 1 0.02 2.45 0.46
47 INT55144 Negative_regulation of Gene_expression of Ahsp 3 0.16 1.39 0.44
48 INT136205 Positive_regulation of Regulation of Cat 1 0.38 0.51 0.43
49 INT15295 Positive_regulation of Regulation of Ahsp 1 0.41 0.41 0.42
50 INT15786 Gene_expression of AHSP 8 0.78 5.12 0.4
51 INT21949 Positive_regulation of Ahsp 4 0.61 1.27 0.35
52 INT84981 Negative_regulation of Gene_expression of CAT 3 0.41 0.35 0.35
53 INT163803 Regulation of Gene_expression of Cat 3 0.61 1.51 0.33
54 INT314342 Positive_regulation of Localization of Cat 2 0.04 1.05 0.31
55 INT144868 Transcription of Cat 3 0.62 1.23 0.29
56 INT211917 Positive_regulation of Positive_regulation of Cat 1 0.62 0.97 0.29
57 INT158564 Negative_regulation of Positive_regulation of Cat 2 0.37 1.27 0.27
58 INT17017 Negative_regulation of Gene_expression of AHSP 1 0.43 2.12 0.23
59 INT58442 Transcription of Cat 3 0.67 0.28 0.22
60 INT210123 Localization of Axin1 1 0.04 0.84 0.17
61 INT66933 Binding of AXIN1 6 0.32 1.8 0.16
62 INT55051 Negative_regulation of Binding of Cat 2 0.35 0.61 0.16
63 INT355976 Negative_regulation of Transcription of Cat 1 0.51 0.31 0.15
64 INT263410 Negative_regulation of Axin1 1 0.01 0 0.14
65 INT181919 Protein_catabolism of CAT 1 0.15 0.54 0.12
66 INT17022 Regulation of AHSP 1 0.24 0.89 0.1
67 INT266463 Positive_regulation of Positive_regulation of CAT 2 0.49 1.85 0.09
68 INT34737 Negative_regulation of Positive_regulation of Ahsp 1 0.37 0.25 0.09
69 INT294014 Regulation of AXIN1 3 0.24 1.04 0.08
70 INT145364 Negative_regulation of AXIN1 2 0.33 0.52 0.08
71 INT73065 Regulation of Localization of Ahsp 1 0.03 0.27 0.08
72 INT12411 Negative_regulation of Negative_regulation of Ahsp 1 0.05 0.22 0.06
73 INT244699 Positive_regulation of AXIN1 1 0.02 0 0.05
74 INT89803 Negative_regulation of Regulation of Cat 3 0.41 1.77 0.03
75 INT229426 Negative_regulation of Localization of Cat 3 0.32 1.06 0.03
76 INT351331 Regulation of Transcription of Cat 1 0.24 0.29 0.03
77 INT89804 Regulation of Positive_regulation of Cat 2 0.26 1.2 0
78 INT294025 Phosphorylation of AXIN1 2 0.38 0.47 0
79 INT17016 Binding of AHSP 1 0.31 0.58 0
80 INT165869 Negative_regulation of Negative_regulation of Cat 1 0.35 0.15 0
81 INT287932 Negative_regulation of Binding of AXIN1 1 0.12 0 0
82 INT293145 Regulation of Negative_regulation of Cat 1 0.18 0.09 0
83 INT107418 Negative_regulation of Regulation of CAT 1 0.31 0 0
84 INT197348 Protein_catabolism of Cat 1 0.32 0.06 0
85 INT307191 Protein_catabolism of Cat 1 0.10 0.19 0
86 INT15785 Positive_regulation of Gene_expression of AHSP 1 0.45 0.32 0
87 INT287935 Positive_regulation of Binding of AXIN1 1 0.14 0 0
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