GO:0021508

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Name floor plate formation
Categary Process
Go Slim No
Go Link GO:0021508
Unique Molecular Interactions 47
Total Molecular Interactions 59
Total Single Events 231
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for floor plate formation. They are ordered first by their pain relevance and then by number of times they were reported for floor plate formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
2 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
3 INT116938 Positive_regulation of GLI2 Positive_regulation of MAPK8 1 0.10 0.07 0.41
4 INT116936 Positive_regulation of GLI2 Positive_regulation of JUN 1 0.12 0.07 0.41
5 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
6 INT104834 Binding of GLI2 and IGKV2OR2-1 1 0.00 0 0.22
7 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
8 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
9 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
10 INT303939 TRAP Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
11 INT303941 CCL2 Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
12 INT104837 IGKV2OR2-1 Negative_regulation of GLI2 1 0.00 0 0.15
13 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
14 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
15 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
16 INT343538 TGFB1 Positive_regulation of Gene_expression of GLI2 1 0.08 0.2 0.05
17 INT262757 SMO Positive_regulation of Regulation of GLI1 1 0.34 0.6 0.04
18 INT270458 Binding of Gli1 and Smo 1 0.00 0.65 0.04
19 INT343545 Binding of GLI2 and ROCK1 1 0.07 0.65 0.03
20 INT343544 Negative_regulation of GLI2 Negative_regulation of Gene_expression of PTHLH 1 0.24 0.53 0.03
21 INT205975 Binding of PTCH1 and Smo 1 0.02 0.72 0
22 INT205974 Smo Positive_regulation of GLI1 1 0.04 0.66 0
23 INT352525 SLC25A16 Negative_regulation of SMO 1 0.00 1.1 0
24 INT207374 Gene_expression of GLI2 Negative_regulation of Gene_expression of Chol1 1 0.04 0 0
25 INT343548 GLI2 Positive_regulation of Gene_expression of PTHLH 1 0.28 0.94 0
26 INT343549 GLI2 Positive_regulation of GYPA 1 0.05 0.95 0
27 INT205965 Binding of Ptch1 and Smo 1 0.03 0.72 0
28 INT207336 Gene_expression of GLI2 Negative_regulation of Gene_expression of CYP27A1 1 0.00 0 0
29 INT343539 GLI2 Regulation of PTHLH 1 0.15 0.25 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for floor plate formation. They are ordered first by their pain relevance and then by number of times they were reported in floor plate formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64170 Gene_expression of GLI2 31 0.46 14.96 3.99
2 INT90926 Positive_regulation of GLI2 12 0.45 4.99 1.74
3 INT104839 Negative_regulation of GLI2 8 0.35 2.7 1.24
4 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
5 INT119674 Localization of GLI2 6 0.52 2.84 0.99
6 INT182322 Negative_regulation of Gene_expression of GLI2 6 0.11 2.37 0.98
7 INT64173 Regulation of Gene_expression of GLI2 4 0.37 2.89 0.88
8 INT289474 Regulation of GLI2 2 0.06 1.08 0.87
9 INT270447 Binding of Smo 2 0.07 2.61 0.78
10 INT104840 Binding of GLI2 6 0.08 1.89 0.72
11 INT205957 Negative_regulation of Smo 4 0.08 2.57 0.6
12 INT356400 Transcription of Smo 1 0.02 0.05 0.3
13 INT119675 Positive_regulation of Localization of GLI2 1 0.32 0.43 0.3
14 INT277474 Positive_regulation of Gene_expression of SMO 1 0.11 0 0.29
15 INT234407 Positive_regulation of Binding of GLI2 2 0.05 1.33 0.28
16 INT216120 Negative_regulation of SMO 2 0.49 3.05 0.27
17 INT303943 Protein_catabolism of GLI2 2 0.11 0 0.22
18 INT182321 Positive_regulation of Gene_expression of GLI2 2 0.28 1.32 0.16
19 INT345344 Regulation of SMO 1 0.23 1.07 0.06
20 INT262772 Binding of SMO 1 0.27 0.59 0.05
21 INT262777 Localization of SMO 1 0.59 0.6 0.04
22 INT252242 Gene_expression of Smo 1 0.01 0.23 0
23 INT207371 Positive_regulation of Transcription of GLI2 1 0.03 0.08 0
24 INT307407 Regulation of Localization of GLI2 1 0.01 0.67 0
25 INT205956 Localization of Smo 1 0.06 0.71 0
26 INT207369 Transcription of GLI2 1 0.05 0.08 0
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