GO:0021527

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Name spinal cord association neuron differentiation
Categary Process
Go Slim No
Go Link GO:0021527
Unique Molecular Interactions 93
Total Molecular Interactions 124
Total Single Events 835
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for spinal cord association neuron differentiation. They are ordered first by their pain relevance and then by number of times they were reported for spinal cord association neuron differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
2 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
3 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
4 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
5 INT213973 Binding of Pax3 and Mthfd1 1 0.00 0.16 1.99
6 INT48790 Negative_regulation of Rtcd1 Negative_regulation of Pax3 1 0.02 0 1.59
7 INT276687 Pax3 Positive_regulation of Nkx1-1 1 0.00 0.59 1.47
8 INT118784 Thop1 Positive_regulation of Protein_catabolism of Pax3 1 0.07 0.07 1.25
9 INT351715 Pax3 Negative_regulation of Adarb1 1 0.00 0 1.19
10 INT189017 Binding of Pax3 and Lmna 1 0.14 0.42 1.16
11 INT48809 Pax3 Negative_regulation of Binding of Tac1 1 0.22 0 1.16
12 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
13 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
14 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
15 INT117908 Em Regulation of Localization of Pax3 1 0.00 0.07 1.03
16 INT49164 Binding of Pax3 and Nka1 1 0.01 0.37 1.01
17 INT49162 Nka1 Negative_regulation of Binding of Pax3 1 0.02 0.37 1.01
18 INT170449 Pax3 Positive_regulation of Spr 1 0.01 0.26 0.99
19 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
20 INT4916 Binding of Pax3 and Wdyhv1 1 0.00 0 0.98
21 INT107951 Pax3 Positive_regulation of Tac1 1 0.11 1.21 0.95
22 INT196591 Binding of Lpar1 and Pax3 1 0.05 1.1 0.92
23 INT334529 Pax3 Positive_regulation of Gene_expression of Ngf 1 0.03 0.31 0.91
24 INT14626 Binding of Dpep1 and Pax3 1 0.01 0 0.87
25 INT185329 Pax3 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.00 0.22 0.87
26 INT213977 Pax3 Negative_regulation of Gene_expression of Il2 1 0.00 0.25 0.86
27 INT189018 Nka1 Regulation of Pax3 1 0.01 0.1 0.81
28 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76
29 INT294908 Pax3 Positive_regulation of Gene_expression of Il1 1 0.03 0.45 0.76
30 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76
31 INT294906 Binding of Pax3 and Tac4 1 0.01 1.15 0.71
32 INT213971 Mthfd1 Positive_regulation of Gene_expression of Pax3 1 0.00 0.14 0.68
33 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67
34 INT170446 Pax3 Positive_regulation of Gene_expression of Spr 1 0.01 0 0.58
35 INT145431 Pax3 Positive_regulation of Positive_regulation of Ros1 1 0.02 0.07 0.57
36 INT126336 Negative_regulation of Binding of Pax3 and Tac1 1 0.01 0.66 0.49
37 INT126337 Pax3 Positive_regulation of Gene_expression of Ifng 1 0.05 0.56 0.44
38 INT126339 Pax3 Regulation of Insrr 1 0.00 0.56 0.44
39 INT126340 Pax3 Regulation of Gene_expression of Ifng 1 0.03 0.56 0.44
40 INT294910 Pax3 Regulation of Positive_regulation of Il1 1 0.02 2.03 0.42
41 INT228055 WNT1 Positive_regulation of CTNND2 1 0.54 1.75 0.42
42 INT15104 Binding of Pax3 and Penk 1 0.01 0 0.37
43 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
44 INT339002 Binding of OPRD1 and GSX1 1 0.00 0 0.3
45 INT339000 Binding of LMOD1 and GSX1 1 0.01 0 0.3
46 INT208940 Pax3 Positive_regulation of Tacr1 1 0.07 0.55 0.29
47 INT208944 Pax3 Positive_regulation of Localization of Nfkb1 1 0.03 0.55 0.29
48 INT339001 GSX1 Positive_regulation of ADCY1 1 0.01 0 0.29
49 INT208941 Positive_regulation of Pax3 Positive_regulation of Tacr1 1 0.05 0.55 0.29
50 INT294905 Binding of Hgf and Pax3 1 0.01 1.54 0.25
51 INT294912 Binding of Pax3 and Tacr3 1 0.01 1.54 0.25
52 INT76865 Lmo4 Positive_regulation of Sds 1 0.02 0.38 0.2
53 INT294904 Binding of Pax3 and Slc12a3 1 0.02 1.9 0.2
54 INT76866 Negative_regulation of Lmo4 Positive_regulation of Sds 1 0.02 0.38 0.2
55 INT231622 Pax3 Positive_regulation of Il17a 1 0.03 1.01 0.19
56 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
57 INT280484 Bdnf Positive_regulation of Gene_expression of Lhx1 1 0.48 1.49 0.11
58 INT309371 Lhx1 Positive_regulation of Gene_expression of Pax2 1 0.08 0.07 0.11
59 INT309372 Lhx5 Positive_regulation of Gene_expression of Pax2 1 0.09 0.07 0.11
60 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
61 INT287877 WNT1 Positive_regulation of Localization of WISP1 1 0.03 0.56 0.05
62 INT287889 WNT1 Positive_regulation of KRT20 1 0.00 0.56 0.05
63 INT345183 Binding of Lhx3 and Trip6 1 0.03 0.66 0.03
64 INT345188 Binding of Lhx3 and Lpar2 1 0.06 0.66 0.03
65 INT251072 Wnt3a Positive_regulation of Axin2 1 0.23 0.29 0
66 INT197309 Ascl1 Regulation of Neurod1 1 0.01 0.13 0
67 INT149115 Cat Negative_regulation of Pax3 1 0.02 0.05 0
68 INT326893 Binding of Tcf4 and Wnt3a 1 0.13 0 0
69 INT259095 Binding of RBBP8 and LMO4 1 0.15 0.73 0
70 INT259093 Binding of TSC1 and LMO4 1 0.02 0.74 0
71 INT311656 Binding of Wnt1 and Spry1 1 0.30 0.39 0
72 INT268521 Binding of WNT1 and MIR221 1 0.02 1.36 0
73 INT297855 Binding of Ndp and Wnt1 1 0.38 1.18 0
74 INT185453 Binding of PRKCB and Lhx1 1 0.35 1.99 0
75 INT244857 Lbx1 Positive_regulation of Lhx1 1 0.37 0 0
76 INT326896 Wnt3a Positive_regulation of Transcription of PLD2 1 0.24 0.06 0
77 INT251070 Wnt3a Positive_regulation of Cldn3 1 0.30 0.29 0
78 INT326894 Wnt3a Positive_regulation of Transcription of Pld1 1 0.24 0.06 0
79 INT259091 Binding of BRCA1 and LMO4 1 0.24 0.74 0
80 INT340561 Mapk1 Negative_regulation of Gene_expression of Pax7 1 0.23 0.25 0
81 INT231519 Binding of PAX7 and POMT1 1 0.02 0.78 0
82 INT197314 Hes5 Regulation of Ascl1 1 0.00 0.14 0
83 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
84 INT197307 Ascl1 Regulation of Neurod6 1 0.00 0.13 0
85 INT231520 Binding of PAX7 and GOPC 1 0.09 0.98 0
86 INT178273 PAX7 Positive_regulation of SEMG1 1 0.02 0.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for spinal cord association neuron differentiation. They are ordered first by their pain relevance and then by number of times they were reported in spinal cord association neuron differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8534 Localization of Pax3 85 0.59 28.71 82.82
2 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47
3 INT4913 Binding of Pax3 52 0.28 9.57 42.67
4 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97
5 INT28336 Positive_regulation of Pax3 37 0.33 20.94 25.66
6 INT70557 Negative_regulation of Localization of Pax3 1 0.36 1.15 17.32
7 INT70556 Positive_regulation of Localization of Pax3 9 0.34 3.13 12.11
8 INT121223 Positive_regulation of Gene_expression of Pax3 17 0.16 4.52 12.06
9 INT70555 Regulation of Pax3 13 0.35 3.62 12.05
10 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
11 INT118782 Protein_catabolism of Pax3 7 0.94 0.46 6.95
12 INT4911 Negative_regulation of Binding of Pax3 7 0.22 1.89 6.17
13 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
14 INT76815 Regulation of Gene_expression of Pax3 4 0.12 3.81 3.65
15 INT170438 Negative_regulation of Gene_expression of Pax3 4 0.04 1.03 3.42
16 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
17 INT48807 Regulation of Binding of Pax3 2 0.13 0 2.59
18 INT121224 Positive_regulation of Positive_regulation of Pax3 5 0.14 2.32 2.4
19 INT70558 Regulation of Localization of Pax3 1 0.20 0.07 2.29
20 INT141833 Gene_expression of WNT1 14 0.75 10.57 2.1
21 INT29035 Negative_regulation of Wnt1 3 0.41 1.47 2
22 INT209366 Negative_regulation of GSX1 1 0.42 0.92 1.72
23 INT244735 Gene_expression of Ascl1 12 0.58 2.48 1.54
24 INT213959 Transcription of Pax3 2 0.03 0.68 1.54
25 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
26 INT189015 Negative_regulation of Positive_regulation of Pax3 1 0.12 0.31 1.31
27 INT170442 Positive_regulation of Binding of Pax3 2 0.17 2.05 1.24
28 INT55599 Gene_expression of GSX1 3 0.65 3.72 1.23
29 INT141834 Negative_regulation of Gene_expression of WNT1 3 0.57 1.31 1.2
30 INT118779 Positive_regulation of Protein_catabolism of Pax3 1 0.47 0.05 1.2
31 INT177615 Gene_expression of PAX7 20 0.65 13.5 1.03
32 INT179583 Gene_expression of Lmo4 5 0.41 1.97 1.03
33 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
34 INT118783 Negative_regulation of Protein_catabolism of Pax3 1 0.35 0.09 0.89
35 INT15247 Negative_regulation of Negative_regulation of Pax3 1 0.16 0 0.86
36 INT141835 Negative_regulation of WNT1 2 0.41 1.02 0.83
37 INT202628 Gene_expression of Wnt1 20 0.67 9.2 0.82
38 INT259113 Gene_expression of LMO4 1 0.78 71.49 0.76
39 INT209367 Binding of GSX1 1 0.47 0.56 0.76
40 INT209368 Positive_regulation of GSX1 1 0.49 0.51 0.67
41 INT55598 Regulation of GSX1 1 0.44 0.95 0.55
42 INT55600 Regulation of Gene_expression of GSX1 1 0.44 0.96 0.55
43 INT340598 Binding of Wnt3a 1 0.33 0.15 0.46
44 INT170437 Regulation of Positive_regulation of Pax3 1 0.03 0 0.45
45 INT228057 Positive_regulation of WNT1 1 0.49 1.8 0.44
46 INT340606 Positive_regulation of Wnt3a 1 0.61 0.49 0.4
47 INT231524 Localization of PAX7 5 0.56 4.2 0.39
48 INT216379 Positive_regulation of Gene_expression of WNT1 5 0.30 3.1 0.34
49 INT185428 Gene_expression of Lhx1 4 0.75 2.6 0.28
50 INT51514 Positive_regulation of Wnt3a 3 0.04 3.32 0.28
51 INT181808 Gene_expression of Pax7 18 0.54 6.22 0.26
52 INT179581 Negative_regulation of Gene_expression of Lmo4 1 0.18 0.06 0.26
53 INT259120 Regulation of Gene_expression of LMO4 1 0.45 5.61 0.23
54 INT310471 Regulation of Ascl1 1 0.34 0.19 0.22
55 INT178280 Regulation of PAX7 4 0.44 1.34 0.21
56 INT353965 Negative_regulation of Gene_expression of Wnt1 1 0.41 0 0.18
57 INT185427 Negative_regulation of Lhx1 4 0.42 3.48 0.17
58 INT310462 Positive_regulation of Gene_expression of Ascl1 1 0.37 0.52 0.17
59 INT259111 Transcription of LMO4 1 0.72 12.56 0.16
60 INT323420 Positive_regulation of Gene_expression of Lmo4 1 0.01 0.71 0.16
61 INT310488 Binding of Ascl1 1 0.28 0.25 0.16
62 INT259110 Negative_regulation of Gene_expression of LMO4 1 0.43 3.47 0.16
63 INT177614 Positive_regulation of PAX7 8 0.54 2.14 0.15
64 INT217569 Binding of Wnt1 2 0.36 1.07 0.15
65 INT259117 Positive_regulation of Gene_expression of LMO4 1 0.70 16.1 0.13
66 INT51512 Negative_regulation of Positive_regulation of Wnt3a 1 0.04 1.3 0.13
67 INT51513 Positive_regulation of Positive_regulation of Wnt3a 1 0.04 1.31 0.13
68 INT309345 Gene_expression of Lhx5 1 0.25 0.06 0.11
69 INT266241 Regulation of Wnt1 1 0.26 0.59 0.09
70 INT310484 Positive_regulation of Ascl1 1 0.37 0.47 0.09
71 INT214463 Binding of Wnt3a 2 0.26 0.23 0.08
72 INT309350 Negative_regulation of Lhx5 1 0.14 0.07 0.08
73 INT259118 Positive_regulation of LMO4 1 0.70 9.69 0.06
74 INT304937 Transcription of Wnt1 1 0.22 0.65 0.05
75 INT226837 Positive_regulation of Gene_expression of Pax7 2 0.49 3.59 0.04
76 INT287956 Regulation of WNT1 2 0.26 2.38 0.04
77 INT185429 Regulation of Lhx1 1 0.12 1.33 0.04
78 INT311648 Regulation of Gene_expression of Wnt1 1 0.39 0.09 0.04
79 INT231525 Negative_regulation of Localization of PAX7 1 0.12 1.05 0.04
80 INT287936 Regulation of Gene_expression of WNT1 1 0.20 1.06 0.04
81 INT231532 Binding of PAX7 3 0.36 3.05 0.03
82 INT273402 Positive_regulation of Localization of PAX7 1 0.37 0.09 0.03
83 INT202633 Positive_regulation of Gene_expression of Wnt1 3 0.43 0.85 0
84 INT244743 Gene_expression of Lhx3 2 0.70 0.74 0
85 INT214465 Localization of Wnt3a 2 0.52 0.29 0
86 INT251053 Gene_expression of Wnt3a 2 0.47 0.5 0
87 INT326853 Positive_regulation of Gene_expression of Wnt3a 1 0.36 0.2 0
88 INT185426 Binding of Lhx1 1 0.36 1.96 0
89 INT340547 Negative_regulation of Gene_expression of Pax7 1 0.30 0.4 0
90 INT259107 Regulation of LMO4 1 0.45 2.68 0
91 INT273390 Regulation of Gene_expression of PAX7 1 0.33 0 0
92 INT340546 Positive_regulation of Pax7 1 0.49 1.07 0
93 INT337424 Phosphorylation of Wnt1 1 0.79 0 0
94 INT251054 Regulation of Localization of Wnt3a 1 0.27 0.07 0
95 INT340539 Negative_regulation of Positive_regulation of Pax7 1 0.30 0.52 0
96 INT259108 Negative_regulation of LMO4 1 0.59 0.74 0
97 INT273394 Negative_regulation of Gene_expression of PAX7 1 0.32 0 0
98 INT311632 Positive_regulation of Wnt1 1 0.43 0.19 0
99 INT177613 Negative_regulation of PAX7 1 0.33 0.27 0
100 INT235058 Localization of Wnt1 1 0.64 0.56 0
101 INT251066 Regulation of Gene_expression of Wnt3a 1 0.31 0.07 0
102 INT340548 Regulation of Gene_expression of Pax7 1 0.32 0.4 0
103 INT259114 Binding of LMO4 1 0.37 4.39 0
104 INT340542 Negative_regulation of Pax7 1 0.30 0.79 0
105 INT326843 Negative_regulation of Gene_expression of Wnt3a 1 0.22 0.29 0
106 INT226833 Transcription of Pax7 1 0.28 0.28 0
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