GO:0021680

From wiki-pain
Jump to: navigation, search
Name cerebellar Purkinje cell layer development
Categary Process
Go Slim No
Go Link GO:0021680
Unique Molecular Interactions 66
Total Molecular Interactions 94
Total Single Events 818
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cerebellar Purkinje cell layer development. They are ordered first by their pain relevance and then by number of times they were reported for cerebellar Purkinje cell layer development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
2 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
3 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08
4 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
5 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
6 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
7 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
8 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
9 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
10 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
11 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34
12 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
13 INT74841 Binding of Cacna1a and Ea2 2 0.01 2.33 1.27
14 INT108729 Binding of CACNA1A and Cacna1a 3 0.13 1.21 0.95
15 INT214410 Binding of ATP1A4 and CACNA1A 1 0.26 0.95 0.7
16 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
17 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49
18 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45
19 INT155752 Binding of CACNA1A and ATCAY 1 0.04 0.86 0.42
20 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4
21 INT158355 Cacna1a Regulation of Alox5 1 0.01 0.7 0.37
22 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34
23 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34
24 INT101551 Binding of CACNA1A and CACNA1F 1 0.07 1.51 0.33
25 INT318323 Binding of GRB2 and HSPA5 1 0.34 0.28 0.31
26 INT151258 Binding of Cacna1a and FCMTE1 1 0.00 0.57 0.3
27 INT142003 Binding of Cacna1a and Etax2 1 0.00 1.02 0.26
28 INT142004 Binding of Cacna1a and TGM6 1 0.00 1.02 0.26
29 INT333927 GLUL Positive_regulation of HSPA5 1 0.17 0.78 0.24
30 INT192864 Binding of Hspa5 and Mela 1 0.25 1.06 0.22
31 INT121807 CACNA1A Regulation of CAV2 1 0.01 0.25 0.2
32 INT130690 Gene_expression of HSPA5 Negative_regulation of Positive_regulation of DDIT3 1 0.21 0.58 0.17
33 INT71329 Cacna1a Regulation of Ea2 1 0.01 0.71 0.15
34 INT71328 Cacna1a Regulation of Atxn2 1 0.00 0.71 0.15
35 INT120559 Binding of Cacna1a and FCMTE1 1 0.02 0.25 0.1
36 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09
37 INT188964 Binding of AMBP and NAGLU 1 0.01 1.27 0.09
38 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09
39 INT192862 Binding of Esr1 and Hspa5 1 0.08 0.68 0.08
40 INT215880 Car2 Regulation of Hspa5 1 0.09 0.66 0.08
41 INT196213 REST Regulation of Gene_expression of CACNA1A 1 0.46 0.08 0.08
42 INT345297 Binding of NAGLU and Lcn2 1 0.01 1.24 0.07
43 INT195221 Binding of CSRP1 and NAGLU 1 0.17 0.25 0.05
44 INT215876 Atf4 Regulation of Hspa5 1 0.22 0.43 0.04
45 INT354983 Cacna1a Regulation of Mpo 1 0.02 0.41 0.04
46 INT354987 Cacna1a Regulation of Localization of LDHA 1 0.00 0.23 0.03
47 INT196208 REST Regulation of CACNA1A 1 0.46 0.06 0
48 INT196216 Binding of CACNA1A and REST 1 0.28 0 0
49 INT261963 Binding of Cacna1a and Tgm2 1 0.08 1.19 0
50 INT206943 Hspa5 Positive_regulation of Atf4 1 0.47 0.62 0
51 INT250496 Gopc Regulation of Positive_regulation of Cacna1a 1 0.37 0 0
52 INT70122 NAGLU Positive_regulation of Localization of Anpep 1 0.10 0 0
53 INT263584 Hspa5 Positive_regulation of Myo1b 1 0.00 1.02 0
54 INT346743 Atf6 Positive_regulation of Hspa5 1 0.00 0 0
55 INT263586 Hspa5 Positive_regulation of Esr1 1 0.15 1.01 0
56 INT307156 Esr1 Positive_regulation of Hspa5 1 0.04 0.79 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cerebellar Purkinje cell layer development. They are ordered first by their pain relevance and then by number of times they were reported in cerebellar Purkinje cell layer development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
2 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
3 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
4 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
5 INT10585 Localization of NAGLU 53 0.80 23.32 12.75
6 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43
7 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91
8 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65
9 INT1973 Positive_regulation of NAGLU 36 0.65 14.78 7
10 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37
11 INT117621 Positive_regulation of HSPA5 17 0.59 13.26 6.06
12 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13
13 INT3163 Gene_expression of NAGLU 28 0.75 15.23 4.98
14 INT110796 Positive_regulation of Positive_regulation of Cacna1a 1 0.49 0.51 4.84
15 INT82731 Transcription of Cacna1a 5 0.56 3.41 4.27
16 INT14619 Positive_regulation of Localization of NAGLU 18 0.62 7.73 3.94
17 INT287526 Negative_regulation of Gene_expression of CACNA1A 1 0.42 4.25 3.81
18 INT53516 Binding of CACNA1A 9 0.47 6.86 3.36
19 INT94045 Regulation of Cacna1a 5 0.42 3.56 3.33
20 INT14281 Gene_expression of Hspa5 44 0.63 34.19 3.31
21 INT78317 Regulation of CACNA1A 8 0.62 7.68 3.08
22 INT85572 Gene_expression of Cacna1a 11 0.66 5.72 3.02
23 INT142940 Positive_regulation of Negative_regulation of Cacna1a 3 0.50 1.65 2.97
24 INT130700 Gene_expression of HSPA5 16 0.75 11.55 2.81
25 INT130702 Positive_regulation of Gene_expression of HSPA5 7 0.59 7.53 2.68
26 INT355244 Negative_regulation of Negative_regulation of Cacna1a 1 0.04 0 2.67
27 INT161575 Localization of CACNA1A 4 0.75 5.28 2.26
28 INT110795 Regulation of Positive_regulation of Cacna1a 2 0.26 0.65 2.07
29 INT38008 Positive_regulation of Gene_expression of NAGLU 6 0.44 6.64 2
30 INT194074 Regulation of NAGLU 5 0.38 2.93 1.87
31 INT354979 Positive_regulation of Localization of Cacna1a 2 0.05 0.86 1.79
32 INT355239 Negative_regulation of Positive_regulation of Cacna1a 1 0.04 0 1.79
33 INT71327 Localization of Cacna1a 3 0.60 2.51 1.7
34 INT58931 Binding of NAGLU 11 0.34 4.47 1.63
35 INT355242 Negative_regulation of Binding of Cacna1a 1 0.04 0.17 1.47
36 INT118559 Positive_regulation of Hspa5 20 0.61 15.66 1.45
37 INT355245 Regulation of Localization of Cacna1a 1 0.04 0 1.43
38 INT90740 Negative_regulation of Cacna1a 3 0.23 1.43 1.38
39 INT82727 Positive_regulation of Transcription of Cacna1a 1 0.01 1.07 1.25
40 INT85571 Positive_regulation of Cacna1a 3 0.50 2.06 1.18
41 INT355243 Negative_regulation of Regulation of Cacna1a 1 0.04 0 1.16
42 INT321650 Negative_regulation of Gene_expression of Cacna1a 2 0.04 0.13 0.95
43 INT94046 Protein_catabolism of Cacna1a 1 0.70 0.83 0.9
44 INT159015 Positive_regulation of Localization of HSPA5 1 0.36 0.33 0.88
45 INT159013 Localization of HSPA5 2 0.42 0.32 0.87
46 INT131964 Positive_regulation of CACNA1A 5 0.61 0.73 0.85
47 INT99156 Binding of HSPA5 3 0.38 0.57 0.84
48 INT103336 Transcription of Cacna1a 2 0.69 1.17 0.68
49 INT141227 Phosphorylation of CACNA1A 1 0.55 0.78 0.66
50 INT189813 Negative_regulation of CACNA1A 4 0.57 3.07 0.55
51 INT122930 Positive_regulation of Gene_expression of CACNA1A 2 0.49 0.91 0.54
52 INT154748 Positive_regulation of Gene_expression of Hspa5 11 0.44 7.66 0.44
53 INT130698 Negative_regulation of Positive_regulation of HSPA5 2 0.36 1.58 0.42
54 INT47915 Negative_regulation of NAGLU 2 0.22 0.66 0.42
55 INT309244 Transcription of HSPA5 1 0.16 2.75 0.36
56 INT99962 Positive_regulation of Gene_expression of Cacna1a 1 0.01 1.1 0.34
57 INT155753 Regulation of Gene_expression of CACNA1A 1 0.27 0.66 0.32
58 INT333957 Regulation of HSPA5 3 0.52 0.61 0.27
59 INT26879 Positive_regulation of Positive_regulation of NAGLU 1 0.54 0.15 0.24
60 INT142482 Positive_regulation of Positive_regulation of HSPA5 1 0.28 1.17 0.22
61 INT172021 Localization of Hspa5 2 0.18 0.93 0.2
62 INT144676 Gene_expression of Hspa5 1 0.06 1.12 0.19
63 INT192842 Binding of Hspa5 3 0.33 1.48 0.16
64 INT154746 Regulation of Positive_regulation of Hspa5 1 0.40 0.18 0.16
65 INT144677 Positive_regulation of Gene_expression of Hspa5 1 0.04 0.59 0.1
66 INT144668 Positive_regulation of Hspa5 1 0.03 0.53 0.09
67 INT192840 Transcription of Hspa5 4 0.47 1.93 0.08
68 INT263572 Regulation of Hspa5 3 0.41 4.15 0.07
69 INT196235 Negative_regulation of Transcription of CACNA1A 1 0.36 0.1 0.07
70 INT333944 Regulation of Regulation of HSPA5 1 0.38 0.14 0.07
71 INT196229 Transcription of CACNA1A 1 0.60 0.24 0.07
72 INT337002 Positive_regulation of Binding of HSPA5 1 0.14 0.05 0.05
73 INT309389 Phosphorylation of Cacna1a 1 0.01 0.54 0.05
74 INT309386 Positive_regulation of Phosphorylation of Cacna1a 1 0.01 0.54 0.05
75 INT130701 Negative_regulation of Gene_expression of HSPA5 1 0.50 0.5 0.05
76 INT289783 Negative_regulation of Hspa5 2 0.22 0.7 0
77 INT263569 Phosphorylation of Hspa5 2 0.42 1.63 0
78 INT263577 Positive_regulation of Transcription of Hspa5 1 0.33 0.95 0
79 INT307137 Regulation of Gene_expression of Hspa5 1 0.16 0.93 0
80 INT327365 Negative_regulation of Positive_regulation of Hspa5 1 0.21 0.68 0
81 INT196237 Positive_regulation of Transcription of CACNA1A 1 0.39 0.14 0
82 INT174710 Regulation of Hspa5 1 0.01 0.14 0
83 INT337007 Negative_regulation of Binding of HSPA5 1 0.14 0 0
84 INT223093 Phosphorylation of NAGLU 1 0.45 0.95 0
85 INT174711 Transcription of Hspa5 1 0.02 0.7 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox