GO:0021702

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Name cerebellar Purkinje cell differentiation
Categary Process
Go Slim No
Go Link GO:0021702
Unique Molecular Interactions 63
Total Molecular Interactions 91
Total Single Events 614
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cerebellar Purkinje cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for cerebellar Purkinje cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
2 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
3 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08
4 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
5 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
6 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
7 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
8 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
9 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
10 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
11 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34
12 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
13 INT74841 Binding of Cacna1a and Ea2 2 0.01 2.33 1.27
14 INT108729 Binding of CACNA1A and Cacna1a 3 0.13 1.21 0.95
15 INT214410 Binding of ATP1A4 and CACNA1A 1 0.26 0.95 0.7
16 INT197233 Positive_regulation of Rora Positive_regulation of Localization of Helt 1 0.00 0 0.68
17 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
18 INT350150 Binding of LPP and ATXN2 1 0.35 1.82 0.54
19 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49
20 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45
21 INT155752 Binding of CACNA1A and ATCAY 1 0.04 0.86 0.42
22 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4
23 INT158355 Cacna1a Regulation of Alox5 1 0.01 0.7 0.37
24 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34
25 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34
26 INT101551 Binding of CACNA1A and CACNA1F 1 0.07 1.51 0.33
27 INT151258 Binding of Cacna1a and FCMTE1 1 0.00 0.57 0.3
28 INT142003 Binding of Cacna1a and Etax2 1 0.00 1.02 0.26
29 INT142004 Binding of Cacna1a and TGM6 1 0.00 1.02 0.26
30 INT131963 Binding of CAV2 and ATXN2 1 0.04 1.39 0.21
31 INT121807 CACNA1A Regulation of CAV2 1 0.01 0.25 0.2
32 INT350152 Binding of ATXN2 and SNRNP70 1 0.13 1.22 0.2
33 INT275461 Binding of Atxn1 and Atxn2 1 0.39 1.1 0.17
34 INT71329 Cacna1a Regulation of Ea2 1 0.01 0.71 0.15
35 INT71328 Cacna1a Regulation of Atxn2 1 0.00 0.71 0.15
36 INT280484 Bdnf Positive_regulation of Gene_expression of Lhx1 1 0.48 1.49 0.11
37 INT309371 Lhx1 Positive_regulation of Gene_expression of Pax2 1 0.08 0.07 0.11
38 INT309372 Lhx5 Positive_regulation of Gene_expression of Pax2 1 0.09 0.07 0.11
39 INT120559 Binding of Cacna1a and FCMTE1 1 0.02 0.25 0.1
40 INT196213 REST Regulation of Gene_expression of CACNA1A 1 0.46 0.08 0.08
41 INT354983 Cacna1a Regulation of Mpo 1 0.02 0.41 0.04
42 INT354987 Cacna1a Regulation of Localization of LDHA 1 0.00 0.23 0.03
43 INT196208 REST Regulation of CACNA1A 1 0.46 0.06 0
44 INT196216 Binding of CACNA1A and REST 1 0.28 0 0
45 INT190890 Binding of RORA and Grip1 1 0.00 0.09 0
46 INT261963 Binding of Cacna1a and Tgm2 1 0.08 1.19 0
47 INT250496 Gopc Regulation of Positive_regulation of Cacna1a 1 0.37 0 0
48 INT240723 Atp2b2 Positive_regulation of Localization of Ca2 1 0.11 0.43 0
49 INT185453 Binding of PRKCB and Lhx1 1 0.35 1.99 0
50 INT244857 Lbx1 Positive_regulation of Lhx1 1 0.37 0 0
51 INT240724 Atp2b2 Positive_regulation of Ca2 1 0.11 0.54 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cerebellar Purkinje cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in cerebellar Purkinje cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
2 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
3 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
4 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
5 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43
6 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91
7 INT125444 Gene_expression of Rora 5 0.75 3.05 8.97
8 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65
9 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37
10 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13
11 INT110796 Positive_regulation of Positive_regulation of Cacna1a 1 0.49 0.51 4.84
12 INT82731 Transcription of Cacna1a 5 0.56 3.41 4.27
13 INT287526 Negative_regulation of Gene_expression of CACNA1A 1 0.42 4.25 3.81
14 INT53516 Binding of CACNA1A 9 0.47 6.86 3.36
15 INT94045 Regulation of Cacna1a 5 0.42 3.56 3.33
16 INT78317 Regulation of CACNA1A 8 0.62 7.68 3.08
17 INT85572 Gene_expression of Cacna1a 11 0.66 5.72 3.02
18 INT142940 Positive_regulation of Negative_regulation of Cacna1a 3 0.50 1.65 2.97
19 INT190881 Positive_regulation of Rora 2 0.43 1.76 2.71
20 INT355244 Negative_regulation of Negative_regulation of Cacna1a 1 0.04 0 2.67
21 INT125442 Negative_regulation of Gene_expression of Rora 5 0.57 2.92 2.54
22 INT197228 Positive_regulation of Gene_expression of Rora 1 0.05 0 2.43
23 INT161575 Localization of CACNA1A 4 0.75 5.28 2.26
24 INT110795 Regulation of Positive_regulation of Cacna1a 2 0.26 0.65 2.07
25 INT354979 Positive_regulation of Localization of Cacna1a 2 0.05 0.86 1.79
26 INT355239 Negative_regulation of Positive_regulation of Cacna1a 1 0.04 0 1.79
27 INT71327 Localization of Cacna1a 3 0.60 2.51 1.7
28 INT355242 Negative_regulation of Binding of Cacna1a 1 0.04 0.17 1.47
29 INT355245 Regulation of Localization of Cacna1a 1 0.04 0 1.43
30 INT90740 Negative_regulation of Cacna1a 3 0.23 1.43 1.38
31 INT82727 Positive_regulation of Transcription of Cacna1a 1 0.01 1.07 1.25
32 INT235157 Gene_expression of Atxn2 3 0.68 6.74 1.23
33 INT460 Negative_regulation of Atxn2 4 0.43 0.85 1.21
34 INT85571 Positive_regulation of Cacna1a 3 0.50 2.06 1.18
35 INT355243 Negative_regulation of Regulation of Cacna1a 1 0.04 0 1.16
36 INT350157 Binding of ATXN2 1 0.33 3.53 1.02
37 INT321650 Negative_regulation of Gene_expression of Cacna1a 2 0.04 0.13 0.95
38 INT94046 Protein_catabolism of Cacna1a 1 0.70 0.83 0.9
39 INT131964 Positive_regulation of CACNA1A 5 0.61 0.73 0.85
40 INT197226 Regulation of Gene_expression of Rora 1 0.04 0 0.71
41 INT103336 Transcription of Cacna1a 2 0.69 1.17 0.68
42 INT141227 Phosphorylation of CACNA1A 1 0.55 0.78 0.66
43 INT189813 Negative_regulation of CACNA1A 4 0.57 3.07 0.55
44 INT167595 Gene_expression of RORA 2 0.05 1.51 0.54
45 INT122930 Positive_regulation of Gene_expression of CACNA1A 2 0.49 0.91 0.54
46 INT275454 Positive_regulation of Atxn2 1 0.50 1.37 0.53
47 INT492 Binding of Atxn2 3 0.48 1.26 0.51
48 INT197215 Regulation of Regulation of Rora 1 0.03 0.08 0.46
49 INT197227 Regulation of Rora 1 0.06 0.08 0.46
50 INT53282 Negative_regulation of Atp2b2 4 0.15 2.6 0.45
51 INT30733 Localization of Atxn2 4 0.55 0.83 0.41
52 INT197214 Binding of Rora 1 0.04 0.09 0.39
53 INT99962 Positive_regulation of Gene_expression of Cacna1a 1 0.01 1.1 0.34
54 INT155753 Regulation of Gene_expression of CACNA1A 1 0.27 0.66 0.32
55 INT185428 Gene_expression of Lhx1 4 0.75 2.6 0.28
56 INT185427 Negative_regulation of Lhx1 4 0.42 3.48 0.17
57 INT491 Positive_regulation of Binding of Atxn2 1 0.35 0.08 0.17
58 INT145362 Positive_regulation of RORA 3 0.49 0.61 0.14
59 INT309345 Gene_expression of Lhx5 1 0.25 0.06 0.11
60 INT240716 Negative_regulation of Gene_expression of Atp2b2 1 0.09 0.78 0.1
61 INT275455 Negative_regulation of Gene_expression of Atxn2 1 0.43 1.07 0.1
62 INT240713 Gene_expression of Atp2b2 1 0.14 1.16 0.09
63 INT125443 Negative_regulation of Rora 1 0.57 0.74 0.08
64 INT309350 Negative_regulation of Lhx5 1 0.14 0.07 0.08
65 INT240714 Negative_regulation of Localization of Atp2b2 1 0.09 1.3 0.08
66 INT196235 Negative_regulation of Transcription of CACNA1A 1 0.36 0.1 0.07
67 INT196229 Transcription of CACNA1A 1 0.60 0.24 0.07
68 INT41372 Regulation of Atxn2 1 0.35 0 0.06
69 INT190888 Positive_regulation of Phosphorylation of RORA 1 0.01 0.25 0.06
70 INT190886 Phosphorylation of RORA 1 0.01 0.25 0.06
71 INT309389 Phosphorylation of Cacna1a 1 0.01 0.54 0.05
72 INT309386 Positive_regulation of Phosphorylation of Cacna1a 1 0.01 0.54 0.05
73 INT185429 Regulation of Lhx1 1 0.12 1.33 0.04
74 INT240715 Localization of Atp2b2 1 0.16 1.07 0.04
75 INT309246 Localization of ATXN2 1 0.10 1.45 0.03
76 INT50097 Regulation of RORA 2 0.01 0 0
77 INT185426 Binding of Lhx1 1 0.36 1.96 0
78 INT249358 Gene_expression of ATXN2 1 0.37 3.59 0
79 INT50098 Negative_regulation of RORA 1 0.02 0 0
80 INT235147 Negative_regulation of Localization of Atxn2 1 0.31 0.46 0
81 INT196237 Positive_regulation of Transcription of CACNA1A 1 0.39 0.14 0
82 INT190887 Binding of RORA 1 0.00 0.1 0
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