GO:0021756

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Name striatum development
Categary Process
Go Slim No
Go Link GO:0021756
Unique Molecular Interactions 119
Total Molecular Interactions 181
Total Single Events 1397
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for striatum development. They are ordered first by their pain relevance and then by number of times they were reported for striatum development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
2 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
3 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
4 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 0.14 0 1.7
5 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
6 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
7 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
8 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
9 INT74185 Cck Negative_regulation of Drd1a 1 0.30 0.1 1.1
10 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
11 INT87854 Binding of Drd1a and Positive_regulation of Localization of Abat 1 0.08 0 0.96
12 INT74184 Cck Regulation of Localization of Drd1a 1 0.32 0.06 0.95
13 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
14 INT136172 NPY Negative_regulation of Positive_regulation of Drd1a 1 0.21 0 0.91
15 INT7292 Binding of Drd1a and Penk 1 0.14 0 0.9
16 INT52760 Oprd1 Regulation of Drd1a 1 0.02 0 0.9
17 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
18 INT29279 Binding of Drd1a and Htr1a 1 0.35 0.2 0.84
19 INT344101 Positive_regulation of Drd1a Positive_regulation of Localization of Abat 1 0.01 0 0.84
20 INT353721 Negative_regulation of Binding of Drd1a and Ghsr 1 0.16 0 0.76
21 INT353720 Binding of Drd1a and Ghsr 1 0.18 0 0.76
22 INT21260 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.05 0 0.76
23 INT329120 Binding of KCNA1 and CNTNAP2 1 0.09 1.23 0.75
24 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74
25 INT329119 Binding of CNTN2 and CNTNAP2 1 0.08 2.41 0.73
26 INT99938 Drd1a Regulation of Transcription of Qrfp 1 0.03 0 0.69
27 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68
28 INT99939 Drd1a Regulation of Qrfp 1 0.03 0 0.68
29 INT317638 Ins1 Positive_regulation of Gene_expression of Drd1a 1 0.14 0.86 0.59
30 INT317634 Ins1 Positive_regulation of Drd1a 1 0.14 0.86 0.59
31 INT5111 DIO2 Positive_regulation of Drd1a 1 0.04 0 0.53
32 INT223925 Drd1a Positive_regulation of Gene_expression of Serpina1 1 0.01 0 0.51
33 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51
34 INT329116 Binding of LGI1 and CNTNAP2 1 0.38 1.3 0.44
35 INT317635 Positive_regulation of Drd1a Positive_regulation of Phosphorylation of Gtf3a 1 0.01 0.53 0.43
36 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4
37 INT32244 Slc3a1 Positive_regulation of Localization of Drd1a 1 0.15 0 0.39
38 INT32243 Drd1a Positive_regulation of Localization of Slc3a1 1 0.15 0 0.39
39 INT28237 BBS2 Positive_regulation of Localization of Cck 1 0.04 0.33 0.39
40 INT344103 Positive_regulation of Drd1a Positive_regulation of Obfc1 1 0.00 0 0.38
41 INT37247 Binding of Drd1a and Drd2 1 0.20 0 0.37
42 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37
43 INT97595 Penk Regulation of Gene_expression of Drd1a 1 0.25 0.1 0.28
44 INT73385 Cfp Regulation of Drd1a 1 0.10 0 0.25
45 INT73384 Positive_regulation of Cfp Regulation of Drd1a 1 0.18 0 0.25
46 INT261465 Binding of Drd1a and Ptgdr 1 0.03 0.1 0.23
47 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
48 INT302712 Binding of Hprt and Hrh1 1 0.25 1.07 0.2
49 INT241070 Klf16 Positive_regulation of Drd1a 1 0.05 0.13 0.12
50 INT317162 Binding of Bdnf and Htt 1 0.51 0.2 0.12
51 INT319315 Binding of Ap2a2 and Htt 1 0.28 0.64 0.11
52 INT305534 Binding of HPRT1 and Tg(CAG-EGFP)D4Nagy 1 0.03 0.7 0.1
53 INT305535 Binding of HPRT1 and Runx1 1 0.41 0.7 0.1
54 INT261454 Akr1d1 Regulation of Drd1a 1 0.00 0.71 0.06
55 INT317181 Binding of Htt and Uts2r 1 0.04 0 0.05
56 INT306527 Binding of Htt and Aifm1 1 0.20 0.82 0.04
57 INT317161 Htt Regulation of Transcription of Bdnf 1 0.48 0.41 0.03
58 INT299368 Mkks Positive_regulation of Mapk8 1 0.41 0.17 0.03
59 INT200311 Htt Positive_regulation of Rest 1 0.05 0.75 0.03
60 INT218308 Binding of HPRT1 and Grb10 1 0.26 0.07 0
61 INT200058 Binding of Ndn and Bbs4 1 0.30 0.29 0
62 INT121179 Binding of Htt and Rest 1 0.07 0.45 0
63 INT89016 Oprd1 Negative_regulation of Drd1a 1 0.06 0 0
64 INT309515 Xrcc6 Regulation of Gene_expression of Htt 1 0.32 0.08 0
65 INT200062 Binding of Ngfr and Bbs4 1 0.30 0.3 0
66 INT318103 Binding of UBC and Hprt 1 0.10 0.52 0
67 INT121177 Binding of Bdnf and Htt 1 0.23 0.44 0
68 INT309521 PRKDC Regulation of Gene_expression of Htt 1 0.41 0.08 0
69 INT121180 Htt Negative_regulation of Bdnf 1 0.43 0.47 0
70 INT309519 Xrcc5 Regulation of Gene_expression of Htt 1 0.18 0.08 0
71 INT186401 Binding of MKKS and MKS1 1 0.09 0.07 0
72 INT339288 Binding of Hprt1 and Il1 1 0.09 0.05 0
73 INT261893 Binding of Htt and Hap1 1 0.13 0.49 0
74 INT317163 Htt Regulation of Bdnf 1 0.29 0.19 0
75 INT309516 Htt Positive_regulation of Gene_expression of Xrcc6 1 0.49 0.06 0
76 INT121176 Htt Regulation of Bdnf 1 0.17 0.77 0
77 INT309509 Negative_regulation of Binding of Xrcc6 and Htt 1 0.31 0.41 0
78 INT309510 Htt Regulation of Gene_expression of Xrcc6 1 0.19 0.15 0
79 INT309508 Htt Negative_regulation of Binding of Xrcc6 1 0.31 0.48 0
80 INT309514 Positive_regulation of Binding of Xrcc6 and Htt 1 0.33 0 0
81 INT215341 Binding of Htt and Sp1 1 0.03 0.25 0
82 INT318100 Binding of Hprt and Ppia 1 0.32 0.52 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for striatum development. They are ordered first by their pain relevance and then by number of times they were reported in striatum development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5858 Positive_regulation of Drd1a 66 0.69 4.51 51.73
2 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43
3 INT13838 Positive_regulation of Drd1a 48 0.70 9.83 23.42
4 INT7680 Regulation of Drd1a 27 0.45 4.52 18.86
5 INT51779 Gene_expression of Drd1a 46 0.66 11.18 17.51
6 INT7020 Negative_regulation of Drd1a 25 0.57 1.84 17.1
7 INT5859 Positive_regulation of Positive_regulation of Drd1a 20 0.55 2.05 15.61
8 INT7682 Binding of Drd1a 22 0.48 1.8 11.83
9 INT16735 Localization of Drd1a 11 0.61 0.35 8.42
10 INT22369 Negative_regulation of Drd1a 15 0.47 6.13 6.87
11 INT21552 Regulation of Drd1a 10 0.57 3.7 6.05
12 INT18366 Negative_regulation of Positive_regulation of Drd1a 6 0.42 0.49 5.54
13 INT101925 Binding of Drd1a 9 0.43 1.82 4.97
14 INT48567 Transcription of Drd1a 7 0.51 2.44 4.54
15 INT113078 Phosphorylation of Drd1a 4 0.30 0.77 4.45
16 INT13333 Regulation of Gene_expression of Drd1a 8 0.36 3.37 4.28
17 INT9349 Gene_expression of BBS2 15 0.49 12.77 4.22
18 INT62901 Positive_regulation of Gene_expression of Drd1a 2 0.57 0.66 3.35
19 INT13335 Negative_regulation of Gene_expression of Drd1a 6 0.34 0.8 3.16
20 INT18365 Positive_regulation of Regulation of Drd1a 4 0.50 1.74 3.04
21 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
22 INT329148 Gene_expression of CNTNAP2 17 0.76 6 2.95
23 INT113077 Positive_regulation of Phosphorylation of Drd1a 1 0.11 0.15 2.87
24 INT64248 Positive_regulation of Positive_regulation of Drd1a 6 0.45 1.97 2.62
25 INT199798 Positive_regulation of BBS2 2 0.50 5.85 2.55
26 INT89992 Positive_regulation of Gene_expression of Drd1a 5 0.39 2.11 2.54
27 INT86462 Transcription of Drd1a 3 0.44 1.86 2.36
28 INT24407 Negative_regulation of Binding of Drd1a 3 0.25 0.81 2.18
29 INT19804 Negative_regulation of Hprt 18 0.59 20.6 2.17
30 INT21046 Regulation of Positive_regulation of Drd1a 3 0.44 0.09 2.06
31 INT13837 Negative_regulation of Positive_regulation of Drd1a 2 0.43 1.43 2.01
32 INT3496 Negative_regulation of HPRT1 7 0.58 25.05 1.92
33 INT88726 Gene_expression of HPRT1 36 0.78 10.12 1.58
34 INT140305 Negative_regulation of Binding of Drd1a 2 0.21 0.54 1.46
35 INT113079 Regulation of Phosphorylation of Drd1a 1 0.06 0.07 1.43
36 INT329143 Binding of CNTNAP2 1 0.47 5.04 1.32
37 INT329140 Localization of CNTNAP2 1 0.73 3.56 1.31
38 INT108997 Localization of Htt 28 0.77 3.76 1.07
39 INT177481 Negative_regulation of BBS2 6 0.31 5.34 1.06
40 INT19803 Gene_expression of Hprt 15 0.67 4.81 1.03
41 INT184839 Localization of Drd1a 4 0.73 0.84 1.03
42 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
43 INT64690 Negative_regulation of Localization of Drd1a 2 0.09 0 0.95
44 INT74183 Positive_regulation of Localization of Drd1a 1 0.32 0.06 0.95
45 INT195946 Gene_expression of Hprt1 9 0.75 1.03 0.89
46 INT99668 Positive_regulation of Binding of Drd1a 2 0.43 0.89 0.87
47 INT28236 Localization of BBS2 2 0.54 1.9 0.83
48 INT154886 Gene_expression of Htt 18 0.76 15.51 0.82
49 INT274178 Binding of BBS2 1 0.27 2.12 0.82
50 INT57008 Positive_regulation of HPRT1 11 0.50 2.81 0.74
51 INT153157 Regulation of Regulation of Drd1a 2 0.25 0.2 0.66
52 INT184848 Positive_regulation of Transcription of Drd1a 1 0.26 0.93 0.65
53 INT140306 Regulation of Binding of Drd1a 1 0.20 0.36 0.64
54 INT72516 Regulation of Binding of Drd1a 2 0.44 0.4 0.63
55 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6
56 INT287206 Regulation of Gene_expression of Htt 6 0.50 3.27 0.57
57 INT215340 Localization of Htt 10 0.61 5.12 0.55
58 INT287204 Protein_catabolism of Htt 6 0.99 2.8 0.53
59 INT329161 Negative_regulation of CNTNAP2 1 0.42 0.73 0.51
60 INT119230 Negative_regulation of Htt 5 0.42 2.99 0.5
61 INT274177 Positive_regulation of Gene_expression of BBS2 2 0.36 1.55 0.49
62 INT329156 Regulation of CNTNAP2 1 0.19 2.35 0.48
63 INT243418 Binding of Htt 14 0.30 5.94 0.44
64 INT165597 Positive_regulation of Htt 8 0.60 4.27 0.44
65 INT132864 Binding of Htt 15 0.46 2.34 0.38
66 INT48566 Regulation of Transcription of Drd1a 1 0.32 0 0.37
67 INT287207 Regulation of Protein_catabolism of Htt 3 0.45 1.73 0.35
68 INT346261 Gene_expression of MKKS 1 0.40 0.66 0.34
69 INT14382 Regulation of BBS2 3 0.43 2.07 0.33
70 INT346249 Phosphorylation of MKKS 1 0.43 0.61 0.31
71 INT183814 Transcription of HPRT1 6 0.69 1.04 0.29
72 INT274176 Negative_regulation of Gene_expression of BBS2 1 0.31 0.94 0.29
73 INT254877 Positive_regulation of Gene_expression of Htt 15 0.64 6.29 0.28
74 INT136052 Negative_regulation of Negative_regulation of Drd1a 1 0.13 0.66 0.27
75 INT49311 Binding of Hprt 3 0.26 0.95 0.26
76 INT329158 Positive_regulation of Gene_expression of CNTNAP2 1 0.49 1.3 0.26
77 INT88725 Regulation of HPRT1 5 0.62 1.28 0.24
78 INT287205 Regulation of Htt 5 0.45 3.56 0.22
79 INT88721 Positive_regulation of Gene_expression of HPRT1 7 0.49 2.16 0.21
80 INT284157 Regulation of Negative_regulation of BBS2 1 0.08 1.08 0.21
81 INT185899 Phosphorylation of HPRT1 1 0.68 0.66 0.21
82 INT41497 Positive_regulation of Hprt1 2 0.49 0.25 0.16
83 INT272845 Transcription of BBS2 1 0.04 0.42 0.16
84 INT110564 Transcription of Hprt 5 0.37 0.82 0.15
85 INT329152 Positive_regulation of CNTNAP2 1 0.49 0.54 0.15
86 INT310770 Positive_regulation of Transcription of HPRT1 1 0.49 0.48 0.14
87 INT163225 Gene_expression of Bbs4 1 0.60 0.09 0.13
88 INT163230 Gene_expression of Mkks 1 0.48 0.09 0.13
89 INT329160 Regulation of Gene_expression of CNTNAP2 1 0.44 0.87 0.11
90 INT88724 Regulation of Gene_expression of HPRT1 2 0.27 1.04 0.09
91 INT296642 Localization of Hprt1 1 0.68 0.18 0.09
92 INT287203 Negative_regulation of Gene_expression of Htt 7 0.37 5.08 0.07
93 INT261890 Positive_regulation of Gene_expression of Htt 1 0.43 0.85 0.06
94 INT233666 Transcription of Hprt1 2 0.67 0.76 0.05
95 INT183818 Positive_regulation of MKKS 1 0.01 1.82 0.05
96 INT317175 Positive_regulation of Localization of Htt 1 0.48 0 0.05
97 INT306521 Transcription of Htt 1 0.69 4.13 0.05
98 INT218301 Binding of HPRT1 2 0.36 0.27 0.04
99 INT331204 Negative_regulation of Binding of Htt 1 0.04 0.64 0.04
100 INT261891 Negative_regulation of Gene_expression of Htt 1 0.37 1.12 0.04
101 INT248181 Positive_regulation of Gene_expression of Hprt1 2 0.49 0 0.03
102 INT195973 Regulation of Gene_expression of Hprt 1 0.52 0.1 0.03
103 INT195947 Regulation of Gene_expression of Hprt1 1 0.44 0.1 0.03
104 INT261190 Regulation of Hprt 3 0.60 0 0
105 INT154887 Transcription of Htt 3 0.66 0 0
106 INT261886 Regulation of Htt 2 0.43 2.06 0
107 INT212915 Positive_regulation of Hprt 2 0.29 0.3 0
108 INT313014 Positive_regulation of Binding of Htt 2 0.13 0.91 0
109 INT341938 Positive_regulation of Negative_regulation of Htt 1 0.07 0.65 0
110 INT254883 Negative_regulation of Positive_regulation of Htt 1 0.05 1.14 0
111 INT304450 Positive_regulation of Gene_expression of Hprt 1 0.18 0 0
112 INT110565 Negative_regulation of Gene_expression of Hprt 1 0.20 0 0
113 INT317177 Negative_regulation of Transcription of Htt 1 0.41 0 0
114 INT177482 Negative_regulation of Negative_regulation of BBS2 1 0.03 0.73 0
115 INT351508 Localization of HPRT1 1 0.41 0.1 0
116 INT309469 Negative_regulation of Localization of Htt 1 0.34 0.13 0
117 INT223030 Positive_regulation of Negative_regulation of HPRT1 1 0.46 0.69 0
118 INT223031 Negative_regulation of Gene_expression of HPRT1 1 0.43 0.13 0
119 INT302709 Negative_regulation of Transcription of Hprt 1 0.30 0.5 0
120 INT317170 Regulation of Binding of Htt 1 0.43 0 0
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