GO:0021766

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Name hippocampus development
Categary Process
Go Slim No
Go Link GO:0021766
Unique Molecular Interactions 493
Total Molecular Interactions 603
Total Single Events 6647
Pain Genes Associated 58

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hippocampus development. They are ordered first by their pain relevance and then by number of times they were reported for hippocampus development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
2 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
3 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
4 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
5 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
6 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
7 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
8 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
9 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
10 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
11 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 0.14 0 1.7
12 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
13 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
14 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
15 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
16 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
17 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
18 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
19 INT162105 Nr4a3 Regulation of ACPT-I 1 0.10 0.26 1.38
20 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
21 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
22 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
23 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
24 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
25 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
26 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
27 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
28 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
29 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
30 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
31 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
32 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
33 INT74185 Cck Negative_regulation of Drd1a 1 0.30 0.1 1.1
34 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
35 INT96906 Plxna3 Regulation of Regulation of Prkaca 1 0.17 0.71 1.08
36 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
37 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
38 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
39 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
40 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
41 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
42 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
43 INT87854 Binding of Drd1a and Positive_regulation of Localization of Abat 1 0.08 0 0.96
44 INT74184 Cck Regulation of Localization of Drd1a 1 0.32 0.06 0.95
45 INT144551 Binding of Lrp8 and Sepp1 1 0.55 1.73 0.93
46 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
47 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
48 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
49 INT136172 NPY Negative_regulation of Positive_regulation of Drd1a 1 0.21 0 0.91
50 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
51 INT7292 Binding of Drd1a and Penk 1 0.14 0 0.9
52 INT52760 Oprd1 Regulation of Drd1a 1 0.02 0 0.9
53 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
54 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
55 INT97738 Mdk Positive_regulation of Mapk3 1 0.08 0.66 0.87
56 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
57 INT29279 Binding of Drd1a and Htr1a 1 0.35 0.2 0.84
58 INT344101 Positive_regulation of Drd1a Positive_regulation of Localization of Abat 1 0.01 0 0.84
59 INT67908 Binding of Cck and Plxna3 1 0.04 0.54 0.84
60 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
61 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
62 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
63 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
64 INT353721 Negative_regulation of Binding of Drd1a and Ghsr 1 0.16 0 0.76
65 INT353720 Binding of Drd1a and Ghsr 1 0.18 0 0.76
66 INT21260 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.05 0 0.76
67 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74
68 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
69 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
70 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
71 INT99938 Drd1a Regulation of Transcription of Qrfp 1 0.03 0 0.69
72 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
73 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68
74 INT99939 Drd1a Regulation of Qrfp 1 0.03 0 0.68
75 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
76 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
77 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
78 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
79 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
80 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
81 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63
82 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
83 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
84 INT281091 Prkacb Positive_regulation of Mdk 1 0.02 0 0.62
85 INT281076 Adcy1 Positive_regulation of Mdk 1 0.07 0 0.62
86 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
87 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
88 INT166387 Binding of Gnb2l1 and Mdk 1 0.30 0.24 0.61
89 INT281086 Prkaca Positive_regulation of Mdk 1 0.08 0 0.61
90 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
91 INT317638 Ins1 Positive_regulation of Gene_expression of Drd1a 1 0.14 0.86 0.59
92 INT317634 Ins1 Positive_regulation of Drd1a 1 0.14 0.86 0.59
93 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
94 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
95 INT263975 NR4A3 Negative_regulation of Positive_regulation of TBK1 1 0.02 1.2 0.57
96 INT112399 Olr897-ps Regulation of Gene_expression of Casp3 1 0.03 0 0.54
97 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
98 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
99 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
100 INT5111 DIO2 Positive_regulation of Drd1a 1 0.04 0 0.53
101 INT49225 Mdk Regulation of Tac1 1 0.00 0 0.53
102 INT223925 Drd1a Positive_regulation of Gene_expression of Serpina1 1 0.01 0 0.51
103 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51
104 INT74517 Binding of Casp3 and Cnrip1 1 0.31 0 0.51
105 INT250080 Grin2b Positive_regulation of Ltp 1 0.22 0.19 0.49
106 INT250081 Grin2a Positive_regulation of Ltp 1 0.20 0.14 0.48
107 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
108 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
109 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
110 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
111 INT198931 Binding of Dlg4 and Lrp8 1 0.06 0.23 0.46
112 INT127400 Negative_regulation of Mdk Negative_regulation of Gene_expression of Elk1 1 0.01 0.71 0.45
113 INT127399 Negative_regulation of Mdk Negative_regulation of Positive_regulation of Nfkb1 1 0.02 0.7 0.45
114 INT127398 Negative_regulation of Mdk Negative_regulation of Gene_expression of Tacr1 1 0.01 0.71 0.45
115 INT127397 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin1 1 0.01 0.71 0.45
116 INT127394 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin2a 1 0.01 0.71 0.45
117 INT127396 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin2a 1 0.00 0.71 0.45
118 INT127401 Negative_regulation of Mdk Negative_regulation of Phosphorylation of Elk1 1 0.01 0.7 0.44
119 INT302369 Binding of Arx and Dlx1 1 0.34 0 0.43
120 INT317635 Positive_regulation of Drd1a Positive_regulation of Phosphorylation of Gtf3a 1 0.01 0.53 0.43
121 INT346218 Positive_regulation of Kras Positive_regulation of Phosphorylation of Mdk 1 0.01 0.71 0.42
122 INT57236 Casp3 Positive_regulation of Prl 1 0.09 0 0.41
123 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 0.22 0.09 0.41
124 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4
125 INT57235 Casp3 Positive_regulation of Localization of Prl 1 0.15 0 0.4
126 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4
127 INT235887 CALM1 Regulation of Akap5 1 0.00 0 0.39
128 INT291256 INS Negative_regulation of Positive_regulation of Mdk 1 0.01 1.65 0.39
129 INT235860 Prkca Regulation of Akap5 1 0.16 0 0.39
130 INT13077 Tac2 Positive_regulation of NKX2-1 1 0.00 0 0.39
131 INT32244 Slc3a1 Positive_regulation of Localization of Drd1a 1 0.15 0 0.39
132 INT32243 Drd1a Positive_regulation of Localization of Slc3a1 1 0.15 0 0.39
133 INT28237 BBS2 Positive_regulation of Localization of Cck 1 0.04 0.33 0.39
134 INT302821 Mdk Negative_regulation of Il1 1 0.02 0.91 0.38
135 INT344103 Positive_regulation of Drd1a Positive_regulation of Obfc1 1 0.00 0 0.38
136 INT272726 Mdk Regulation of Negative_regulation of Prkca 1 0.00 0 0.38
137 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38
138 INT52960 Casp3 Negative_regulation of Positive_regulation of Ltp 1 0.02 0 0.37
139 INT37247 Binding of Drd1a and Drd2 1 0.20 0 0.37
140 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37
141 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
142 INT152453 Gsk3b Regulation of Nfkb1 1 0.02 1.68 0.36
143 INT235861 Binding of Prkaca and Akap5 1 0.20 0 0.35
144 INT71925 Binding of Ptprs and Positive_regulation of Racgap1 1 0.10 0 0.35
145 INT187064 ARSD Negative_regulation of CYP19A1 1 0.22 0.7 0.35
146 INT250076 Grin2a Regulation of Positive_regulation of Ltp 1 0.10 0.06 0.35
147 INT302371 Dlx1 Regulation of Gene_expression of Arx 1 0.28 0 0.35
148 INT235862 Binding of Ppp3r2 and Akap5 1 0.01 0 0.35
149 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 0.01 0.23 0.35
150 INT304532 Binding of Mdk and Mapk1 1 0.02 0.63 0.35
151 INT66369 Pomc Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
152 INT304529 Negative_regulation of Binding of Mdk and Mapk1 1 0.02 0.63 0.35
153 INT71924 Ptprs Positive_regulation of Racgap1 1 0.10 0 0.35
154 INT235859 Binding of Prkca and Akap5 1 0.13 0 0.35
155 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
156 INT190652 Mdk Positive_regulation of Phosphorylation of Mapk1 2 0.50 0.85 0.33
157 INT236006 HTR1A Regulation of Grin2b 1 0.00 0 0.33
158 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
159 INT302841 Mdk Positive_regulation of Positive_regulation of TNF 1 0.01 0.35 0.33
160 INT223872 Mdk Regulation of Binding of Ltp 1 0.21 0 0.32
161 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.97 0.32
162 INT263974 Binding of ADRB2 and NR4A3 1 0.01 0.5 0.32
163 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
164 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31
165 INT342810 Binding of Adarb1 and Gsk3b 1 0.00 0.36 0.3
166 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
167 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
168 INT250079 Grin2b Regulation of Ltp 1 0.18 0.31 0.29
169 INT291242 Positive_regulation of Mdk Regulation of Mapk1 1 0.03 1.28 0.29
170 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
171 INT154194 Binding of KCNK2 and Akap5 1 0.08 0.19 0.29
172 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
173 INT60181 Binding of HTR5A and Pik3c3 1 0.03 0.1 0.29
174 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
175 INT191328 Mir327 Negative_regulation of Mdk 1 0.00 0 0.28
176 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
177 INT134927 CYP19A1 Positive_regulation of Gene_expression of MME 1 0.30 1.04 0.28
178 INT212289 Vsnl1 Negative_regulation of Grin2a 1 0.04 0.38 0.28
179 INT134930 MME Positive_regulation of Gene_expression of CYP19A1 1 0.30 1.04 0.28
180 INT97595 Penk Regulation of Gene_expression of Drd1a 1 0.25 0.1 0.28
181 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
182 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
183 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 0.11 0.28 0.27
184 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
185 INT342164 Binding of Csf2 and Nkx2-1 1 0.01 0.52 0.26
186 INT73385 Cfp Regulation of Drd1a 1 0.10 0 0.25
187 INT291261 INS Positive_regulation of Phosphorylation of Mdk 1 0.01 0.28 0.25
188 INT73384 Positive_regulation of Cfp Regulation of Drd1a 1 0.18 0 0.25
189 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
190 INT250075 Binding of Hpcal4 and Negative_regulation of Gene_expression of Grin2a 1 0.03 0 0.24
191 INT261465 Binding of Drd1a and Ptgdr 1 0.03 0.1 0.23
192 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
193 INT149791 Binding of Lrp8 and Reln 4 0.36 0.38 0.22
194 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22
195 INT302367 Dlx2 Regulation of Gene_expression of Arx 1 0.59 0.23 0.22
196 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22
197 INT349344 Bdnf Negative_regulation of Casp3 1 0.13 0.96 0.22
198 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22
199 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
200 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21

Single Events

The table below shows the top 100 pain related interactions that have been reported for hippocampus development. They are ordered first by their pain relevance and then by number of times they were reported in hippocampus development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
2 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
3 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
4 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
5 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
6 INT5858 Positive_regulation of Drd1a 66 0.69 4.51 51.73
7 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
8 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
9 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
10 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
11 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
12 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72
13 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
14 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
15 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43
16 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
17 INT13838 Positive_regulation of Drd1a 48 0.70 9.83 23.42
18 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
19 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21
20 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
21 INT7680 Regulation of Drd1a 27 0.45 4.52 18.86
22 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
23 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26
24 INT51779 Gene_expression of Drd1a 46 0.66 11.18 17.51
25 INT7020 Negative_regulation of Drd1a 25 0.57 1.84 17.1
26 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
27 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
28 INT98647 Positive_regulation of Mdk 65 0.59 32.93 15.67
29 INT5859 Positive_regulation of Positive_regulation of Drd1a 20 0.55 2.05 15.61
30 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
31 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
32 INT20066 Gene_expression of Mdk 38 0.76 21.41 13.4
33 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
34 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
35 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
36 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
37 INT7682 Binding of Drd1a 22 0.48 1.8 11.83
38 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
39 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
40 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
41 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
42 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
43 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
44 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
45 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
46 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21
47 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
48 INT10597 Gene_expression of Cyp19a1 27 0.78 7.48 9.11
49 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
50 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
51 INT16735 Localization of Drd1a 11 0.61 0.35 8.42
52 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34
53 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
54 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
55 INT98178 Localization of Casp3 32 0.65 21.01 7.77
56 INT22369 Negative_regulation of Drd1a 15 0.47 6.13 6.87
57 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41
58 INT185252 Gene_expression of Dlx2 7 0.71 8.8 6.24
59 INT57232 Binding of Casp3 22 0.36 9.42 6.2
60 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
61 INT21552 Regulation of Drd1a 10 0.57 3.7 6.05
62 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
63 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
64 INT135760 Regulation of Gene_expression of Cyp19a1 2 0.62 1.15 5.81
65 INT36921 Regulation of Mdk 14 0.26 6.49 5.8
66 INT67693 Binding of Grin2a 9 0.38 1.74 5.68
67 INT85075 Phosphorylation of Mdk 22 0.61 10.29 5.55
68 INT18366 Negative_regulation of Positive_regulation of Drd1a 6 0.42 0.49 5.54
69 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
70 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
71 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37
72 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
73 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
74 INT101925 Binding of Drd1a 9 0.43 1.82 4.97
75 INT32256 Gene_expression of PLXNA3 11 0.75 7.8 4.92
76 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
77 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
78 INT48567 Transcription of Drd1a 7 0.51 2.44 4.54
79 INT113078 Phosphorylation of Drd1a 4 0.30 0.77 4.45
80 INT13333 Regulation of Gene_expression of Drd1a 8 0.36 3.37 4.28
81 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
82 INT9349 Gene_expression of BBS2 15 0.49 12.77 4.22
83 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
84 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
85 INT103999 Positive_regulation of Phosphorylation of Grin2a 5 0.38 3.12 3.94
86 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
87 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
88 INT99889 Transcription of SRD5A1 5 0.71 1.45 3.74
89 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
90 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61
91 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56
92 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
93 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
94 INT86977 Positive_regulation of Nr4a3 7 0.10 0.73 3.5
95 INT15930 Positive_regulation of Ptprs 8 0.67 7.02 3.48
96 INT46725 Localization of Anxa3 4 0.48 4.53 3.43
97 INT62901 Positive_regulation of Gene_expression of Drd1a 2 0.57 0.66 3.35
98 INT21156 Binding of PLXNA3 21 0.36 7.95 3.3
99 INT37601 Negative_regulation of Ptprs 8 0.42 3.7 3.29
100 INT13335 Negative_regulation of Gene_expression of Drd1a 6 0.34 0.8 3.16
101 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
102 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
103 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
104 INT18365 Positive_regulation of Regulation of Drd1a 4 0.50 1.74 3.04
105 INT116376 Transcription of Cyp19a1 2 0.40 0.74 3.04
106 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01
107 INT90611 Positive_regulation of Positive_regulation of Grin2a 4 0.63 1.89 3
108 INT133809 Negative_regulation of Gene_expression of CYP19A1 9 0.43 7.67 2.99
109 INT113277 Positive_regulation of Gene_expression of CYP19A1 13 0.69 10.23 2.97
110 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96
111 INT41099 Localization of Mdk 5 0.64 2.38 2.89
112 INT113077 Positive_regulation of Phosphorylation of Drd1a 1 0.11 0.15 2.87
113 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74
114 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
115 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
116 INT64248 Positive_regulation of Positive_regulation of Drd1a 6 0.45 1.97 2.62
117 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
118 INT36923 Binding of Mdk 7 0.35 3.81 2.58
119 INT86980 Transcription of Nr4a3 4 0.45 0.24 2.58
120 INT105730 Localization of Grin2a 7 0.67 0.64 2.56
121 INT199798 Positive_regulation of BBS2 2 0.50 5.85 2.55
122 INT89992 Positive_regulation of Gene_expression of Drd1a 5 0.39 2.11 2.54
123 INT36920 Positive_regulation of Gene_expression of Mdk 8 0.49 2.03 2.53
124 INT101055 Regulation of GRIN2B 4 0.61 1.39 2.5
125 INT131112 Phosphorylation of Casp3 7 0.63 4.1 2.46
126 INT185961 Gene_expression of Bcan 1 0.18 1.97 2.46
127 INT82347 Regulation of PLXNA3 5 0.60 4.59 2.45
128 INT86462 Transcription of Drd1a 3 0.44 1.86 2.36
129 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
130 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
131 INT71048 Transcription of CYP19A1 11 0.72 8.74 2.24
132 INT24407 Negative_regulation of Binding of Drd1a 3 0.25 0.81 2.18
133 INT302340 Positive_regulation of Gene_expression of Dlx2 2 0.64 3.43 2.15
134 INT70066 Positive_regulation of Localization of Anxa3 1 0.01 2.34 2.14
135 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
136 INT111113 Binding of CYP19A1 15 0.36 9.17 2.12
137 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12
138 INT13075 Binding of NKX2-1 6 0.05 0.12 2.08
139 INT342803 Positive_regulation of Transcription of Cyp19a1 1 0.30 0.33 2.08
140 INT21046 Regulation of Positive_regulation of Drd1a 3 0.44 0.09 2.06
141 INT342815 Positive_regulation of Transcription of SRD5A1 1 0.49 0.33 2.04
142 INT13837 Negative_regulation of Positive_regulation of Drd1a 2 0.43 1.43 2.01
143 INT158442 Gene_expression of Nkx2-1 21 0.59 8.47 1.99
144 INT190644 Regulation of Negative_regulation of Mdk 6 0.26 2.49 1.98
145 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
146 INT149761 Negative_regulation of MAS1 5 0.29 1.91 1.95
147 INT81347 Regulation of Cyp19a1 7 0.40 2.1 1.94
148 INT64609 Negative_regulation of PLXNA3 5 0.57 3.64 1.94
149 INT151942 Regulation of Negative_regulation of Grin2b 2 0.41 0.41 1.92
150 INT74595 Regulation of Transcription of Grin2a 2 0.42 0.66 1.92
151 INT103624 Negative_regulation of Gene_expression of Grin2a 5 0.56 1.58 1.9
152 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
153 INT204018 Localization of Gsk3b 27 0.71 13.67 1.87
154 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
155 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
156 INT151174 Negative_regulation of Transcription of Grin2a 3 0.40 0 1.8
157 INT74594 Regulation of Transcription of Grin2b 1 0.42 0.17 1.8
158 INT130440 Phosphorylation of GRIN2B 2 0.79 2.93 1.79
159 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
160 INT131572 Negative_regulation of Phosphorylation of Mdk 4 0.15 1.67 1.71
161 INT16622 Positive_regulation of PLXNA3 6 0.67 5.2 1.69
162 INT257820 Positive_regulation of PAFAH1B1 1 0.68 11.09 1.69
163 INT112339 Localization of Cyp11a1 2 0.71 0.94 1.68
164 INT10596 Positive_regulation of Cyp19a1 10 0.42 2.08 1.62
165 INT174107 Binding of Plxna3 4 0.21 2.95 1.62
166 INT149762 Regulation of MAS1 8 0.31 5.34 1.61
167 INT114163 Regulation of HTR5A 2 0.27 0.2 1.61
168 INT98648 Negative_regulation of Positive_regulation of Mdk 5 0.50 3.03 1.56
169 INT272884 Gene_expression of Hdac2 19 0.43 14.55 1.48
170 INT106749 Negative_regulation of Negative_regulation of Casp3 6 0.34 5.12 1.48
171 INT107379 Localization of GRIN2B 2 0.73 0.86 1.48
172 INT140305 Negative_regulation of Binding of Drd1a 2 0.21 0.54 1.46
173 INT140843 Regulation of Phosphorylation of Casp3 1 0.25 0.37 1.44
174 INT113079 Regulation of Phosphorylation of Drd1a 1 0.06 0.07 1.43
175 INT127889 Regulation of Gene_expression of CYP19A1 11 0.62 6.7 1.41
176 INT10570 Positive_regulation of Cyp11a1 9 0.47 2.67 1.4
177 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
178 INT109222 Positive_regulation of Negative_regulation of Cdk5 2 0.50 0.23 1.39
179 INT158709 Negative_regulation of Phosphorylation of Cdk5 1 0.40 0 1.39
180 INT86979 Positive_regulation of Transcription of Nr4a3 1 0.02 0.13 1.38
181 INT86978 Regulation of Nr4a3 1 0.02 0.06 1.37
182 INT171690 Transcription of Casp3 8 0.55 2.62 1.36
183 INT97943 Positive_regulation of Protein_catabolism of Casp3 7 0.28 7.4 1.35
184 INT214073 Binding of TSC1 9 0.37 22 1.34
185 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
186 INT105729 Negative_regulation of Localization of Grin2a 3 0.38 0.08 1.29
187 INT135665 Negative_regulation of Negative_regulation of Mdk 3 0.27 0.76 1.28
188 INT223121 Positive_regulation of Positive_regulation of Mdk 6 0.20 2.7 1.27
189 INT198387 Regulation of SRD5A1 2 0.60 1.29 1.26
190 INT249527 Positive_regulation of Positive_regulation of Grin2b 2 0.37 1.12 1.22
191 INT95347 Negative_regulation of GRIN2B 1 0.57 0 1.19
192 INT272879 Negative_regulation of Hdac2 8 0.37 5.96 1.17
193 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16
194 INT207610 Positive_regulation of Phosphorylation of Mdk 7 0.26 2.66 1.15
195 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15
196 INT78266 Localization of NKX2-1 2 0.73 0.16 1.12
197 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11
198 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11
199 INT181973 Positive_regulation of MAS1 8 0.49 7.64 1.07
200 INT177481 Negative_regulation of BBS2 6 0.31 5.34 1.06
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