GO:0021769

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Name orbitofrontal cortex development
Categary Process
Go Slim No
Go Link GO:0021769
Unique Molecular Interactions 15
Total Molecular Interactions 21
Total Single Events 211
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for orbitofrontal cortex development. They are ordered first by their pain relevance and then by number of times they were reported for orbitofrontal cortex development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
2 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
3 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
4 INT9717 Binding of Egf and Fgfr1 1 0.15 0 0.22
5 INT228501 Binding of AAVS1 and Fgfr1 1 0.01 0.57 0.07
6 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07
7 INT303560 Binding of Fgfr2 and Fgf22 1 0.41 0.89 0.07
8 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
9 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
10 INT335017 Fgf23 Positive_regulation of Fgfr1 1 0.23 0.59 0.04
11 INT303558 Binding of Fgfr2 and Dysf 1 0.01 0.44 0.03
12 INT205611 Gm6668 Negative_regulation of Fgfr1 1 0.01 1.59 0
13 INT183091 Binding of FGF2 and FGFR2 1 0.03 0.79 0
14 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
15 INT183089 Positive_regulation of Binding of FGF2 and FGFR2 1 0.04 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for orbitofrontal cortex development. They are ordered first by their pain relevance and then by number of times they were reported in orbitofrontal cortex development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28734 Gene_expression of Reln 7 0.74 5.76 4.33
2 INT109391 Gene_expression of Fgfr1 7 0.56 1.78 3.67
3 INT119218 Positive_regulation of Fgfr1 4 0.58 1.11 3.05
4 INT265064 Binding of Reln 1 0.02 2.7 1.83
5 INT265066 Positive_regulation of Reln 1 0.02 1.59 1.72
6 INT28735 Localization of Reln 2 0.12 1.49 1.7
7 INT159312 Regulation of Reln 4 0.43 1.79 1.4
8 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08
9 INT183182 Negative_regulation of FGFR2 2 0.29 1.25 0.84
10 INT166537 Localization of Fgfr1 5 0.40 2.69 0.69
11 INT173508 Negative_regulation of Fgfr1 4 0.55 5.08 0.66
12 INT158136 Binding of FGFR2 9 0.26 4.5 0.63
13 INT146775 Phosphorylation of Fgfr1 1 0.53 0.8 0.62
14 INT150949 Gene_expression of Fgfr1 6 0.63 5.71 0.57
15 INT146776 Transcription of Fgfr1 1 0.45 0.67 0.49
16 INT146777 Regulation of Transcription of Fgfr1 1 0.23 0.67 0.49
17 INT146778 Negative_regulation of Fgfr2 1 0.32 0.66 0.48
18 INT188371 Regulation of Localization of Fgfr1 1 0.10 1.02 0.43
19 INT202626 Negative_regulation of Fgfr2 2 0.41 2.48 0.42
20 INT150948 Positive_regulation of Gene_expression of Fgfr1 3 0.15 3.19 0.32
21 INT180696 Positive_regulation of Gene_expression of Fgfr1 1 0.32 0.08 0.28
22 INT176080 Gene_expression of Fgfr2 4 0.68 2.34 0.24
23 INT285474 Negative_regulation of Gene_expression of Fgfr1 2 0.40 2.15 0.24
24 INT223739 Binding of Fgfr2 3 0.30 0.94 0.22
25 INT188373 Positive_regulation of Localization of Fgfr1 1 0.19 1.09 0.21
26 INT173515 Negative_regulation of Transcription of Fgfr1 1 0.06 0.92 0.21
27 INT303539 Binding of Fgfr1 3 0.45 0.96 0.2
28 INT159314 Positive_regulation of Gene_expression of Reln 1 0.44 0.47 0.2
29 INT173503 Transcription of Fgfr1 1 0.08 0.92 0.2
30 INT99718 Positive_regulation of Gene_expression of FGFR2 9 0.49 4.47 0.12
31 INT188374 Negative_regulation of Fgfr1 1 0.22 0.68 0.1
32 INT265068 Transcription of Reln 1 0.03 0.07 0.09
33 INT250851 Binding of Fgfr1 1 0.10 0.19 0.08
34 INT303546 Binding of Fgfr2 1 0.46 0.74 0.06
35 INT188372 Negative_regulation of Localization of Fgfr1 1 0.22 0.66 0.06
36 INT303538 Positive_regulation of Fgfr1 3 0.65 0.92 0.03
37 INT303544 Positive_regulation of Negative_regulation of Fgfr1 1 0.47 1.07 0.03
38 INT303525 Localization of Fgfr2 1 0.72 0.28 0.03
39 INT303547 Positive_regulation of Negative_regulation of Fgfr2 1 0.48 1.07 0.03
40 INT303536 Localization of Fgfr1 1 0.70 0.28 0.03
41 INT207729 Regulation of FGFR2 4 0.22 2.35 0
42 INT238985 Positive_regulation of FGFR2 3 0.49 1.19 0
43 INT99716 Transcription of FGFR2 2 0.34 0.22 0
44 INT305351 Positive_regulation of Regulation of FGFR2 2 0.37 0.97 0
45 INT99715 Regulation of Gene_expression of FGFR2 2 0.22 0.19 0
46 INT303555 Negative_regulation of Gene_expression of FGFR2 2 0.41 0.31 0
47 INT310246 Positive_regulation of Positive_regulation of Fgfr1 1 0.31 0 0
48 INT202623 Negative_regulation of Gene_expression of Fgfr2 1 0.32 0 0
49 INT319036 Gene_expression of Fgfr2 1 0.48 0.08 0
50 INT99717 Positive_regulation of Transcription of FGFR2 1 0.10 0.08 0
51 INT183117 Positive_regulation of Binding of FGFR2 1 0.09 0.81 0
52 INT180708 Regulation of Fgfr1 1 0.09 0 0
53 INT303524 Positive_regulation of Fgfr2 1 0.66 0.22 0
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