GO:0021794

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Name thalamus development
Categary Process
Go Slim No
Go Link GO:0021794
Unique Molecular Interactions 86
Total Molecular Interactions 128
Total Single Events 1413
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for thalamus development. They are ordered first by their pain relevance and then by number of times they were reported for thalamus development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25
2 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
3 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
4 INT147506 Binding of Ncam1 and Gtf3a 1 0.03 0.88 0.99
5 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98
6 INT333303 Zic2 Regulation of Gene_expression of Slc6a4 1 0.60 0.47 0.91
7 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76
8 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76
9 INT329120 Binding of KCNA1 and CNTNAP2 1 0.09 1.23 0.75
10 INT169769 Mir16-1 Regulation of Slc6a4 1 0.24 0 0.74
11 INT333296 Gtf3a Regulation of Gene_expression of Slc6a4 1 0.01 0 0.74
12 INT329119 Binding of CNTN2 and CNTNAP2 1 0.08 2.41 0.73
13 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69
14 INT74727 Binding of Slc6a4 and Hpic1 1 0.00 0.49 0.68
15 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
16 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68
17 INT333305 Zic2 Positive_regulation of Transcription of Slc6a4 1 0.68 0 0.66
18 INT144107 Binding of SLC6A2 and SLC6A4 1 0.00 0.18 0.62
19 INT59201 ecs Positive_regulation of Ncam1 1 0.01 0.98 0.59
20 INT333302 Zic2 Positive_regulation of Slc6a4 1 0.68 0.11 0.57
21 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
22 INT128431 SLC6A4 Regulation of S100A4 1 0.48 0.65 0.53
23 INT47745 Binding of Slc6a4 and Htr2a 1 0.33 0.09 0.52
24 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
25 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5
26 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
27 INT113248 Olr1259 Negative_regulation of Slc6a4 1 0.00 0.23 0.44
28 INT329116 Binding of LGI1 and CNTNAP2 1 0.38 1.3 0.44
29 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
30 INT154782 Binding of SLC6A4 and Ndst2 1 0.01 0 0.37
31 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
32 INT140666 TNF Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
33 INT235869 Binding of Slc6a4 and Ppp2ca 1 0.04 0.21 0.31
34 INT235877 Prkaca Regulation of Transcription of Slc6a4 1 0.06 0.13 0.31
35 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3
36 INT235874 Camk2a Positive_regulation of Slc6a4 1 0.11 0.14 0.28
37 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
38 INT333298 Zic2 Regulation of Transcription of Slc6a4 1 0.44 0.09 0.2
39 INT316072 Binding of Cd3e and Ncam1 1 0.01 0.4 0.18
40 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17
41 INT235883 Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
42 INT235879 Regulation of Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
43 INT144027 Binding of Slc6a4 and Pdgfrb 1 0.23 0.25 0.14
44 INT175196 Binding of NCOR1 and NUP62 1 0.02 0.84 0.12
45 INT249465 Positive_regulation of Slc6a4 Positive_regulation of Gene_expression of Bdnf 1 0.31 0.3 0.08
46 INT326382 Binding of Gdnf and Ncam1 1 0.01 0.3 0.08
47 INT249466 Slc6a4 Positive_regulation of Phosphorylation of Creb1 1 0.09 0.36 0.07
48 INT333304 Zic2 Positive_regulation of Gene_expression of Slc6a4 1 0.68 0.1 0.06
49 INT333297 Gtf3a Positive_regulation of Gene_expression of Slc6a4 1 0.01 0.1 0.06
50 INT218953 Esyt1 Negative_regulation of Ncor1 1 0.00 0.1 0.05
51 INT332895 Binding of Ppara and Ncor1 1 0.31 0.15 0.05
52 INT321652 Binding of Slc6a3 and Slc6a4 1 0.26 0.07 0.05
53 INT321654 Binding of Slc6a4 and Uts2r 1 0.05 0.07 0.05
54 INT333301 Binding of Slc6a4 and Zic2 1 0.47 0 0.03
55 INT333307 Gene_expression of Zic2 Positive_regulation of Gene_expression of Slc6a4 1 0.45 0.05 0.03
56 INT322236 Agt Regulation of Gene_expression of Slc6a4 1 0.42 0.63 0
57 INT322251 Slc6a4 Regulation of Gene_expression of Agtrap 1 0.43 0.63 0
58 INT127457 Ccl2 Positive_regulation of Gene_expression of Slc6a4 1 0.13 0 0
59 INT332881 Negative_regulation of Binding of Hdac3 and Ncor1 1 0.28 0.18 0
60 INT127464 Binding of PAH and Slc6a4 1 0.08 0 0
61 INT302321 Negative_regulation of Binding of Lrp6 and SOST 1 0.16 0.26 0
62 INT284920 Binding of HDAC1 and NCOR1 1 0.03 0.13 0
63 INT322248 Slc6a4 Regulation of Gene_expression of Agt 1 0.42 0.63 0
64 INT302320 Binding of Lrp6 and SOST 1 0.18 0.26 0
65 INT335887 Akt1 Regulation of Lrp6 1 0.06 0.15 0
66 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0
67 INT332896 Binding of Hdac3 and Ncor1 1 0.31 1.38 0
68 INT332882 Ncor1 Negative_regulation of Gene_expression of Arntl 1 0.31 0.17 0
69 INT322238 Slc6a4 Regulation of Gene_expression of Ace 1 0.37 0.63 0
70 INT322256 Ace Regulation of Gene_expression of Slc6a4 1 0.37 0.63 0
71 INT332892 Ncor1 Positive_regulation of Hdac3 1 0.45 0.18 0
72 INT333306 Ephb1 Regulation of Gene_expression of Slc6a4 1 0.19 0.21 0
73 INT332879 Negative_regulation of Ncor1 Positive_regulation of Hdac3 1 0.28 0.18 0
74 INT333295 Gtf3a Positive_regulation of Slc6a4 1 0.01 0 0
75 INT322247 Slc6a4 Regulation of Gene_expression of Htr2a 1 0.13 0.63 0
76 INT333300 Positive_regulation of Zic2 Positive_regulation of Slc6a4 1 0.45 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for thalamus development. They are ordered first by their pain relevance and then by number of times they were reported in thalamus development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
2 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23
3 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84
4 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
5 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
6 INT18672 Gene_expression of Ncam1 54 0.78 36.64 18.79
7 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
8 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
9 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28
10 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23
11 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55
12 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45
13 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21
14 INT119651 Binding of Slc6a4 12 0.32 4.65 7.07
15 INT15092 Positive_regulation of SLC6A4 17 0.67 7.32 6.7
16 INT109714 Transcription of SLC6A4 7 0.72 3.8 6.19
17 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23
18 INT119711 Positive_regulation of Slc6a4 16 0.69 4.44 5.21
19 INT122675 Negative_regulation of Gene_expression of Slc6a4 14 0.59 6.4 4.69
20 INT133905 Gene_expression of Ncam1 24 0.78 10.2 4.62
21 INT137691 Positive_regulation of Gene_expression of Ncam1 9 0.68 2.3 4.24
22 INT56027 Positive_regulation of Ncam1 12 0.69 4.96 4.1
23 INT79343 Positive_regulation of Slc6a4 10 0.50 1.77 4.05
24 INT140670 Negative_regulation of Gene_expression of SLC6A4 4 0.51 2.7 3.88
25 INT103021 Transcription of Slc6a4 16 0.70 3.93 3.77
26 INT99889 Transcription of SRD5A1 5 0.71 1.45 3.74
27 INT137688 Regulation of Gene_expression of Ncam1 1 0.60 1.21 3.65
28 INT99291 Transcription of Slc6a4 7 0.46 1.16 3.28
29 INT127455 Positive_regulation of Gene_expression of Slc6a4 9 0.59 5.62 3.2
30 INT100190 Regulation of Gene_expression of Slc6a4 5 0.39 1.8 3.14
31 INT124438 Regulation of Gene_expression of Slc6a4 9 0.62 3.5 2.97
32 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96
33 INT329148 Gene_expression of CNTNAP2 17 0.76 6 2.95
34 INT80320 Negative_regulation of Gene_expression of Slc6a4 4 0.42 0.85 2.6
35 INT120726 Positive_regulation of Gene_expression of Slc6a4 4 0.68 0.51 2.34
36 INT152554 Regulation of Transcription of SLC6A4 3 0.62 1.52 2.18
37 INT137690 Negative_regulation of Gene_expression of Ncam1 3 0.50 3.37 2.18
38 INT342815 Positive_regulation of Transcription of SRD5A1 1 0.49 0.33 2.04
39 INT133906 Positive_regulation of Gene_expression of Ncam1 6 0.70 1.9 2
40 INT195430 Regulation of Positive_regulation of SLC6A4 1 0.42 1.01 1.98
41 INT125974 Localization of Slc6a4 5 0.66 2.27 1.97
42 INT243017 Negative_regulation of Binding of Slc6a4 1 0.25 0.22 1.89
43 INT141937 Negative_regulation of Regulation of SLC6A4 1 0.41 0.27 1.8
44 INT56028 Regulation of Ncam1 6 0.38 3.6 1.78
45 INT133904 Positive_regulation of Ncam1 7 0.50 4.01 1.57
46 INT147808 Positive_regulation of Gene_expression of SLC6A4 4 0.50 1.03 1.57
47 INT329143 Binding of CNTNAP2 1 0.47 5.04 1.32
48 INT329140 Localization of CNTNAP2 1 0.73 3.56 1.31
49 INT198387 Regulation of SRD5A1 2 0.60 1.29 1.26
50 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
51 INT47839 Localization of Slc6a4 4 0.79 0.96 1.14
52 INT147286 Negative_regulation of Regulation of Slc6a4 1 0.21 0 1.13
53 INT154493 Regulation of Gene_expression of SRD5A1 3 0.45 0.58 1.03
54 INT128444 Phosphorylation of SLC6A4 2 0.61 0.49 1.02
55 INT129674 Regulation of Negative_regulation of Slc6a4 1 0.38 0.46 0.98
56 INT131649 Positive_regulation of Negative_regulation of Slc6a4 2 0.44 0.32 0.91
57 INT286694 Positive_regulation of Localization of Slc6a4 1 0.26 0 0.9
58 INT152101 Regulation of Transcription of Slc6a4 1 0.14 0 0.89
59 INT243015 Regulation of Binding of Slc6a4 1 0.16 0.43 0.75
60 INT147809 Localization of SLC6A4 5 0.71 1.69 0.74
61 INT78800 Negative_regulation of Ncam1 2 0.36 0.58 0.69
62 INT286687 Phosphorylation of Slc6a4 1 0.46 0 0.58
63 INT286690 Positive_regulation of Phosphorylation of Slc6a4 1 0.28 0 0.58
64 INT327658 Regulation of Ncor1 1 0.13 0 0.56
65 INT106568 Regulation of Regulation of Slc6a4 1 0.22 0.07 0.52
66 INT271164 Negative_regulation of Transcription of Slc6a4 1 0.04 0.47 0.52
67 INT329161 Negative_regulation of CNTNAP2 1 0.42 0.73 0.51
68 INT95163 Binding of Ncam1 3 0.32 1.02 0.5
69 INT129524 Regulation of Regulation of SLC6A4 1 0.26 0.16 0.5
70 INT342811 Positive_regulation of Gene_expression of SRD5A1 1 0.45 0.22 0.5
71 INT352021 Negative_regulation of Negative_regulation of SLC6A4 1 0.08 0.2 0.5
72 INT329156 Regulation of CNTNAP2 1 0.19 2.35 0.48
73 INT150168 Negative_regulation of Transcription of SLC6A4 1 0.42 0.16 0.47
74 INT150167 Positive_regulation of Transcription of SLC6A4 1 0.45 0.16 0.46
75 INT95161 Localization of Ncam1 5 0.80 1.01 0.45
76 INT171223 Regulation of Ncam1 5 0.20 3.81 0.43
77 INT333278 Negative_regulation of Transcription of Slc6a4 2 0.37 0.56 0.36
78 INT140668 Positive_regulation of Negative_regulation of SLC6A4 1 0.56 0.23 0.36
79 INT63268 Negative_regulation of Ncor1 5 0.32 0.51 0.34
80 INT148455 Positive_regulation of Negative_regulation of Slc6a4 1 0.50 0.18 0.34
81 INT124930 Positive_regulation of Binding of SLC6A4 1 0.40 0.06 0.33
82 INT102992 Regulation of Negative_regulation of SRD5A1 4 0.60 3.59 0.29
83 INT89620 Phosphorylation of Ncam1 1 0.19 0.52 0.28
84 INT335875 Regulation of Lrp6 1 0.57 0.43 0.27
85 INT341784 Positive_regulation of Phosphorylation of SLC6A4 1 0.29 0.07 0.26
86 INT329158 Positive_regulation of Gene_expression of CNTNAP2 1 0.49 1.3 0.26
87 INT95162 Negative_regulation of Localization of Ncam1 2 0.37 0.17 0.24
88 INT79350 Positive_regulation of Binding of Slc6a4 1 0.34 0 0.24
89 INT257786 Localization of NCOR1 1 0.68 0.36 0.24
90 INT126794 Binding of SRD5A1 2 0.36 3.26 0.22
91 INT340198 Regulation of Transcription of Slc6a4 1 0.36 0.66 0.22
92 INT56026 Positive_regulation of Regulation of Ncam1 1 0.37 0.24 0.22
93 INT103022 Positive_regulation of Transcription of Slc6a4 2 0.44 0.52 0.21
94 INT260506 Binding of Ncam1 2 0.20 0.1 0.2
95 INT63271 Regulation of Ncor1 2 0.26 0.8 0.18
96 INT335861 Localization of Lrp6 1 0.69 0.54 0.17
97 INT63270 Gene_expression of Ncor1 7 0.56 0.65 0.15
98 INT329152 Positive_regulation of CNTNAP2 1 0.49 0.54 0.15
99 INT202816 Negative_regulation of Ncam1 3 0.30 0.64 0.14
100 INT252012 Negative_regulation of Positive_regulation of Ncam1 1 0.22 1.3 0.14
101 INT208202 Localization of Ncam1 2 0.42 0.56 0.11
102 INT236875 Localization of SRD5A1 2 0.73 0.8 0.11
103 INT329160 Regulation of Gene_expression of CNTNAP2 1 0.44 0.87 0.11
104 INT332749 Positive_regulation of Binding of Slc6a4 1 0.23 0.19 0.07
105 INT171527 Gene_expression of NCOR1 3 0.51 0.49 0.06
106 INT354439 Positive_regulation of NCOR1 1 0.35 0.15 0.06
107 INT236876 Negative_regulation of Localization of SRD5A1 1 0.41 0.81 0.06
108 INT335865 Positive_regulation of Phosphorylation of Lrp6 1 0.64 0.46 0.05
109 INT335862 Phosphorylation of Lrp6 1 0.76 0.37 0.05
110 INT247634 Negative_regulation of Localization of Ncam1 1 0.05 0.1 0.05
111 INT210871 Transcription of Ncor1 3 0.50 0 0.03
112 INT218945 Localization of Ncor1 1 0.32 0.15 0.03
113 INT342653 Regulation of Transcription of Ncor1 1 0.31 0 0.03
114 INT178534 Positive_regulation of SRD5A1 2 0.44 1.23 0
115 INT63269 Positive_regulation of Ncor1 2 0.66 0.05 0
116 INT236869 Negative_regulation of Negative_regulation of SRD5A1 2 0.41 2.68 0
117 INT342659 Positive_regulation of Gene_expression of Ncor1 1 0.35 0 0
118 INT332921 Localization of Ncor1 1 0.04 0.05 0
119 INT335872 Positive_regulation of Gene_expression of Lrp6 1 0.46 0.18 0
120 INT326360 Phosphorylation of Ncam1 1 0.44 0.28 0
121 INT210872 Regulation of Gene_expression of Ncor1 1 0.06 0 0
122 INT333286 Negative_regulation of Positive_regulation of Slc6a4 1 0.50 0 0
123 INT332828 Gene_expression of Ncor1 1 0.50 0.16 0
124 INT333280 Regulation of Localization of Slc6a4 1 0.38 0.18 0
125 INT332848 Negative_regulation of Binding of Ncor1 1 0.32 0.36 0
126 INT332842 Binding of Ncor1 1 0.36 0.91 0
127 INT101927 Negative_regulation of Binding of Slc6a4 1 0.59 0 0
128 INT127454 Negative_regulation of Positive_regulation of Slc6a4 1 0.32 0 0
129 INT347117 Negative_regulation of Binding of Lrp6 1 0.28 0.5 0
130 INT335866 Regulation of Transcription of Lrp6 1 0.42 0.25 0
131 INT335881 Gene_expression of Lrp6 1 0.62 0.09 0
132 INT335873 Transcription of Lrp6 1 0.64 0.25 0
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