GO:0021846

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Name cell proliferation in forebrain
Categary Process
Go Slim No
Go Link GO:0021846
Unique Molecular Interactions 66
Total Molecular Interactions 101
Total Single Events 464
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell proliferation in forebrain. They are ordered first by their pain relevance and then by number of times they were reported for cell proliferation in forebrain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
2 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
3 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
4 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
5 INT302369 Binding of Arx and Dlx1 1 0.34 0 0.43
6 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
7 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
8 INT302371 Dlx1 Regulation of Gene_expression of Arx 1 0.28 0 0.35
9 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
10 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
11 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
12 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
13 INT302367 Dlx2 Regulation of Gene_expression of Arx 1 0.59 0.23 0.22
14 INT302372 Arx Negative_regulation of Gene_expression of Calb2 1 0.13 0.05 0.18
15 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
16 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
17 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
18 INT309372 Lhx5 Positive_regulation of Gene_expression of Pax2 1 0.09 0.07 0.11
19 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
20 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
21 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
22 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
23 INT341004 Reln Positive_regulation of Fabp7 1 0.03 0.12 0.08
24 INT229493 Binding of Ndel1 and Disc1 1 0.13 0.68 0.06
25 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
26 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
27 INT170328 Gene_expression of Ido1 Positive_regulation of Hmga2 1 0.01 0.13 0.04
28 INT341002 Reln Positive_regulation of Gene_expression of Fabp7 1 0.04 0.32 0.04
29 INT341009 Nrg1 Positive_regulation of Gene_expression of Fabp7 1 0.10 0.49 0.04
30 INT316060 Binding of Erbb4 and Ncor2 1 0.12 0.41 0.03
31 INT229508 Binding of Fez1 and Disc1 1 0.03 0.34 0.03
32 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
33 INT316056 Binding of Ncor2 and Tab2 1 0.12 0.41 0.03
34 INT233280 Binding of PBX1 and Emx2 1 0.19 0.68 0
35 INT196948 Hmga2 Positive_regulation of Hdac1 1 0.36 0.23 0
36 INT233273 Binding of Emx2 and Tbca 1 0.01 0.34 0
37 INT343744 mn Negative_regulation of Regulation of Wnt7a 1 0.01 0.1 0
38 INT341006 Reln Regulation of Gene_expression of Fabp7 1 0.03 0 0
39 INT251072 Wnt3a Positive_regulation of Axin2 1 0.23 0.29 0
40 INT326893 Binding of Tcf4 and Wnt3a 1 0.13 0 0
41 INT196959 Hmga2 Positive_regulation of Localization of E2f1 1 0.54 0.24 0
42 INT302364 Binding of Arx and Reln 1 0.32 1.25 0
43 INT302370 Binding of Arx and Dcx 1 0.35 1.25 0
44 INT341020 PIK3CB Regulation of Gene_expression of Fabp7 1 0.02 0 0
45 INT196940 Positive_regulation of Hmga2 Positive_regulation of E2f1 1 0.50 0.47 0
46 INT341012 Binding of Fabp7 and Vim 1 0.03 0.16 0
47 INT326896 Wnt3a Positive_regulation of Transcription of PLD2 1 0.24 0.06 0
48 INT233271 Binding of Emx2 and Hoxa10 1 0.13 0.36 0
49 INT196961 Binding of Hmga2 and Rb1 1 0.48 6.47 0
50 INT251070 Wnt3a Positive_regulation of Cldn3 1 0.30 0.29 0
51 INT326894 Wnt3a Positive_regulation of Transcription of Pld1 1 0.24 0.06 0
52 INT217151 Gene_expression of MIR98 Negative_regulation of HMGA2 1 0.24 1.08 0
53 INT302373 Binding of Arx and Tuba1a 1 0.30 1.26 0
54 INT268600 Mirlet7a-1 Regulation of HMGA2 1 0.01 0.72 0
55 INT196956 Binding of Hmga2 and Hdac1 1 0.25 0.23 0
56 INT196947 Binding of Rb1 and Positive_regulation of Hmga2 1 0.50 0.3 0
57 INT235167 Binding of Hdac3 and Ncor2 1 0.01 0.28 0
58 INT302368 Binding of Arx and Pafah1b1 1 0.27 1.25 0
59 INT196951 Hmga2 Positive_regulation of E2f1 1 0.50 0.98 0
60 INT337403 MIR200A Positive_regulation of ZEB2 1 0.01 0.17 0
61 INT235164 Binding of Atxn1 and Ncor2 1 0.15 0.42 0
62 INT196942 Binding of E2f1 and Hmga2 1 0.39 0.87 0
63 INT217142 MIR98 Regulation of Gene_expression of HMGA2 1 0.40 2.22 0
64 INT196953 Hmga2 Negative_regulation of Rb1 1 0.59 0.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell proliferation in forebrain. They are ordered first by their pain relevance and then by number of times they were reported in cell proliferation in forebrain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
2 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
3 INT302338 Gene_expression of Arx 1 0.77 2.8 4.93
4 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
5 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
6 INT34977 Gene_expression of Hmga2 11 0.76 12.39 3.07
7 INT55090 Positive_regulation of Wnt7a 13 0.37 2.25 2.2
8 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
9 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
10 INT302345 Positive_regulation of Gene_expression of Arx 1 0.69 1.06 1.4
11 INT190880 Binding of Ncor2 11 0.27 2.24 1.34
12 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
13 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
14 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
15 INT185250 Gene_expression of Fabp7 6 0.41 4.78 1.02
16 INT127647 Regulation of Wnt7a 3 0.07 1.28 1.01
17 INT34978 Negative_regulation of Gene_expression of Hmga2 2 0.42 1.53 0.95
18 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
19 INT302342 Localization of Arx 1 0.80 0.94 0.83
20 INT168981 Negative_regulation of Disc1 2 0.52 2.93 0.7
21 INT302339 Regulation of Arx 1 0.45 1.23 0.66
22 INT28958 Negative_regulation of Wnt7a 3 0.45 0.49 0.65
23 INT88987 Gene_expression of HMGA2 8 0.77 10.46 0.64
24 INT182677 Gene_expression of Emx2 11 0.78 2.14 0.59
25 INT127648 Gene_expression of Wnt7a 2 0.13 1.11 0.56
26 INT168982 Negative_regulation of Negative_regulation of Disc1 1 0.42 1.28 0.54
27 INT88170 Positive_regulation of HMGA2 2 0.69 2 0.48
28 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
29 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
30 INT340598 Binding of Wnt3a 1 0.33 0.15 0.46
31 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
32 INT302343 Negative_regulation of Arx 1 0.51 0.76 0.4
33 INT340606 Positive_regulation of Wnt3a 1 0.61 0.49 0.4
34 INT88167 Negative_regulation of Positive_regulation of HMGA2 1 0.41 0.16 0.35
35 INT302351 Regulation of Gene_expression of Arx 1 0.45 0 0.35
36 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34
37 INT302349 Regulation of Negative_regulation of Arx 1 0.39 0.27 0.31
38 INT88988 Positive_regulation of Gene_expression of HMGA2 1 0.69 4.05 0.29
39 INT196937 Positive_regulation of Hmga2 3 0.68 2.47 0.28
40 INT51514 Positive_regulation of Wnt3a 3 0.04 3.32 0.28
41 INT238367 Positive_regulation of Binding of Ncor2 1 0.11 0.32 0.27
42 INT302350 Negative_regulation of Gene_expression of Arx 1 0.58 0.26 0.26
43 INT250836 Binding of Fgf8 3 0.35 0.66 0.24
44 INT250833 Localization of Fgf8 1 0.74 0.46 0.21
45 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21
46 INT55089 Positive_regulation of Positive_regulation of Wnt7a 2 0.27 0.06 0.16
47 INT236573 Positive_regulation of Ncor2 1 0.49 1.06 0.15
48 INT250835 Positive_regulation of Fgf8 1 0.50 0.42 0.14
49 INT238365 Negative_regulation of Binding of Ncor2 1 0.09 0.26 0.14
50 INT259191 Positive_regulation of Disc1 1 0.44 1.46 0.14
51 INT302356 Binding of Arx 1 0.37 0.07 0.13
52 INT51512 Negative_regulation of Positive_regulation of Wnt3a 1 0.04 1.3 0.13
53 INT51513 Positive_regulation of Positive_regulation of Wnt3a 1 0.04 1.31 0.13
54 INT262100 Gene_expression of Ncor2 3 0.42 0.31 0.12
55 INT197449 Negative_regulation of Emx2 1 0.51 0.2 0.12
56 INT340941 Negative_regulation of Gene_expression of Fabp7 1 0.20 0.55 0.12
57 INT340967 Binding of Fabp7 1 0.13 0 0.12
58 INT309345 Gene_expression of Lhx5 1 0.25 0.06 0.11
59 INT302341 Positive_regulation of Arx 1 0.44 0.4 0.11
60 INT302347 Transcription of Arx 1 0.53 0.33 0.09
61 INT214463 Binding of Wnt3a 2 0.26 0.23 0.08
62 INT170298 Regulation of Gene_expression of Hmga2 1 0.01 0.48 0.08
63 INT309350 Negative_regulation of Lhx5 1 0.14 0.07 0.08
64 INT197443 Positive_regulation of Gene_expression of Emx2 1 0.47 0.1 0.08
65 INT88990 Binding of HMGA2 1 0.48 0.95 0.07
66 INT340973 Regulation of Fabp7 1 0.14 0.17 0.07
67 INT170300 Positive_regulation of Gene_expression of Hmga2 2 0.68 4.51 0.06
68 INT170302 Regulation of Hmga2 2 0.44 0.94 0.06
69 INT340947 Positive_regulation of Gene_expression of Fabp7 1 0.24 0.4 0.06
70 INT340953 Negative_regulation of Fabp7 1 0.18 0.56 0.06
71 INT159426 Positive_regulation of Gene_expression of Wnt7a 1 0.10 0.51 0.05
72 INT316040 Localization of Ncor2 2 0.28 0.57 0.03
73 INT310486 Transcription of Emx2 1 0.32 0 0.03
74 INT76371 Protein_catabolism of Hmga2 1 0.02 0.06 0.03
75 INT214465 Localization of Wnt3a 2 0.52 0.29 0
76 INT251053 Gene_expression of Wnt3a 2 0.47 0.5 0
77 INT326853 Positive_regulation of Gene_expression of Wnt3a 1 0.36 0.2 0
78 INT196931 Phosphorylation of Hmga2 1 0.80 0.4 0
79 INT266460 Positive_regulation of Binding of Wnt7a 1 0.04 0.06 0
80 INT196923 Binding of Hmga2 1 0.47 2.5 0
81 INT307205 Regulation of Binding of Ncor2 1 0.28 0.1 0
82 INT300344 Localization of HMGA2 1 0.42 1.75 0
83 INT217195 Negative_regulation of HMGA2 1 0.55 3.54 0
84 INT340939 Positive_regulation of Fabp7 1 0.21 0 0
85 INT340956 Negative_regulation of Negative_regulation of Fabp7 1 0.18 0.17 0
86 INT302361 Positive_regulation of Localization of Arx 1 0.46 0.15 0
87 INT251054 Regulation of Localization of Wnt3a 1 0.27 0.07 0
88 INT266459 Binding of Wnt7a 1 0.03 0.06 0
89 INT233225 Regulation of Gene_expression of Emx2 1 0.23 0.09 0
90 INT337465 Positive_regulation of ZEB2 1 0.18 0.17 0
91 INT196932 Negative_regulation of Binding of Hmga2 1 0.42 0.24 0
92 INT196938 Negative_regulation of Hmga2 1 0.42 0.23 0
93 INT268581 Regulation of HMGA2 1 0.18 0.72 0
94 INT250830 Regulation of Protein_catabolism of Fgf8 1 0.45 0.08 0
95 INT311651 Positive_regulation of Fgf8 1 0.46 0.26 0
96 INT251066 Regulation of Gene_expression of Wnt3a 1 0.31 0.07 0
97 INT340969 Regulation of Gene_expression of Fabp7 1 0.21 0.29 0
98 INT250846 Positive_regulation of Protein_catabolism of Fgf8 1 0.50 0.07 0
99 INT217225 Negative_regulation of Negative_regulation of HMGA2 1 0.55 2.4 0
100 INT248200 Gene_expression of Disc1 1 0.51 0.54 0
101 INT343743 Negative_regulation of Regulation of Wnt7a 1 0.04 0.1 0
102 INT326843 Negative_regulation of Gene_expression of Wnt3a 1 0.22 0.29 0
103 INT196921 Localization of Hmga2 1 0.74 0.44 0
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