GO:0021854

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Name hypothalamus development
Categary Process
Go Slim No
Go Link GO:0021854
Unique Molecular Interactions 292
Total Molecular Interactions 455
Total Single Events 4196
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hypothalamus development. They are ordered first by their pain relevance and then by number of times they were reported for hypothalamus development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
2 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
3 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
4 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
5 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
6 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
7 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
8 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
9 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
10 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
11 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
12 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
13 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
14 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
15 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
16 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
17 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
18 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
19 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
20 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59
21 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
22 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
23 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
24 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
25 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
26 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
27 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
28 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
29 INT29714 Crh Regulation of Localization of LH 2 0.26 0 1.19
30 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
31 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
32 INT29713 Crh Negative_regulation of Localization of Gnrhr 1 0.39 0 1.12
33 INT209088 Binding of Ceacam3 and Crhr1 1 0.34 1.26 1.11
34 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
35 INT38936 Binding of Avp and Crh 7 0.40 0.82 1.04
36 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
37 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1
38 INT5612 Cck Positive_regulation of Localization of Crh 1 0.65 0.16 1
39 INT175805 Crh Positive_regulation of Gene_expression of POMC 1 0.12 1.07 0.99
40 INT31494 Pomc Regulation of Crh 2 0.12 0.13 0.97
41 INT36002 Negative_regulation of Crh Negative_regulation of LH 2 0.29 0.66 0.96
42 INT62449 Gnrh1 Regulation of Crh 1 0.40 0.34 0.91
43 INT66371 Pomc Regulation of Gene_expression of Crh 2 0.49 0 0.88
44 INT21006 Oprl1 Regulation of Localization of Crh 1 0.19 0 0.84
45 INT64629 Binding of Gal and Crh 1 0.18 0.1 0.83
46 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
47 INT64627 Binding of Oxt and Crh 1 0.07 0.1 0.83
48 INT36003 Crh Positive_regulation of Localization of LH 2 0.45 0 0.79
49 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
50 INT79532 Crh Regulation of Ugt1a10 1 0.00 0 0.76
51 INT28620 Penk Regulation of Crh 2 0.40 0.25 0.75
52 INT30838 Crh Negative_regulation of D230030E09Rik 1 0.17 0.1 0.73
53 INT5971 Il1a Positive_regulation of Crh 2 0.51 0.57 0.71
54 INT313778 Gene_expression of Crhq1 Negative_regulation of Localization of Crh 1 0.05 0.66 0.71
55 INT12022 Crh Positive_regulation of Localization of Prl 1 0.02 0.14 0.7
56 INT26198 Positive_regulation of Crh Positive_regulation of Localization of POMC 1 0.38 0 0.7
57 INT55205 Prl Positive_regulation of Localization of Crh 1 0.47 0 0.69
58 INT55209 Prl Positive_regulation of Crh 1 0.51 0 0.69
59 INT253825 Cck Positive_regulation of Crh 1 0.74 0 0.69
60 INT135119 Binding of Pomc and Crh 1 0.35 0 0.67
61 INT103905 Gh Positive_regulation of Positive_regulation of Crh 1 0.08 0.9 0.66
62 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
63 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
64 INT97508 Negative_regulation of Il1b Positive_regulation of Crh 1 0.31 0.89 0.65
65 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
66 INT33561 Crh Positive_regulation of POMC 3 0.45 1.19 0.64
67 INT34212 PSG2 Regulation of Localization of Crh 1 0.02 0.09 0.63
68 INT34211 DNM2 Regulation of Localization of Crh 1 0.01 0.09 0.63
69 INT23576 Binding of Penk and Crh 2 0.18 0 0.62
70 INT20162 Crh Regulation of GNRH1 2 0.02 0.07 0.62
71 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61
72 INT91391 Crh Regulation of Localization of Gnrh1 2 0.36 1.78 0.61
73 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
74 INT57246 Crh Positive_regulation of Positive_regulation of Caprin2 1 0.01 0.55 0.6
75 INT104050 Binding of Crh and Nts 1 0.40 0 0.6
76 INT59540 Crh Regulation of Gnrh1 2 0.36 2.61 0.58
77 INT91393 Crh Positive_regulation of SST 1 0.01 0.73 0.58
78 INT54620 IL1B Positive_regulation of Crh 1 0.01 0.39 0.58
79 INT62445 Pomc Negative_regulation of Localization of Crh 1 0.12 0.07 0.58
80 INT30268 Binding of Gnrh1 and Crh 1 0.45 0.65 0.57
81 INT77367 IFNA1 Positive_regulation of Positive_regulation of Crh 1 0.05 0.76 0.57
82 INT30267 Binding of Crh and Gnrhr 1 0.33 0.65 0.57
83 INT94499 Tnf Positive_regulation of Gene_expression of Crh 1 0.27 0.97 0.56
84 INT141020 Crh Positive_regulation of Gene_expression of Pomc 1 0.05 0.17 0.55
85 INT87557 Crh Positive_regulation of Prkaca 1 0.27 0 0.52
86 INT130161 IgG-2a Positive_regulation of Gene_expression of Crhr1 1 0.01 0 0.52
87 INT130158 Pomc Regulation of Gene_expression of Crhr1 1 0.20 0 0.52
88 INT130163 Pomc Positive_regulation of Gene_expression of Crhr1 1 0.15 0 0.52
89 INT130159 IgG-2a Regulation of Gene_expression of Crhr1 1 0.01 0 0.52
90 INT55208 Prl Negative_regulation of Localization of Crh 1 0.43 0 0.51
91 INT127337 Crh Regulation of LOC308670 1 0.01 0 0.51
92 INT62446 Il6 Positive_regulation of Crh 1 0.22 0.05 0.5
93 INT27066 Crh Positive_regulation of Localization of Oxt 1 0.40 0 0.48
94 INT59546 Avp Positive_regulation of Localization of Crh 1 0.05 0.08 0.47
95 INT59548 Negative_regulation of Avp Positive_regulation of Crh 1 0.04 0.08 0.47
96 INT28619 Negative_regulation of Penk Regulation of Crh 1 0.41 0 0.46
97 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
98 INT62447 Gnrh1 Regulation of Localization of Crh 1 0.40 0.17 0.45
99 INT57983 Il1b Regulation of Crh 1 0.37 0.09 0.44
100 INT57981 Regulation of Il1b Positive_regulation of Crh 1 0.22 0.1 0.44
101 INT30083 Binding of Crh and Lvp1 1 0.00 0.35 0.44
102 INT139486 Oprm1 Positive_regulation of Crh 1 0.27 0.1 0.42
103 INT55202 Crh Positive_regulation of Negative_regulation of Prl 1 0.51 0 0.41
104 INT91107 Positive_regulation of Ptgs1 Positive_regulation of Localization of Crh 1 0.00 0.56 0.41
105 INT73772 NR3C1 Regulation of Regulation of Crh 1 0.02 0.68 0.38
106 INT41460 Crh Regulation of Pomc 1 0.10 0.1 0.36
107 INT26197 Qrfp Regulation of Localization of Crh 1 0.02 0 0.36
108 INT41461 Crh Regulation of Localization of Pomc 1 0.10 0.1 0.36
109 INT66368 Pomc Regulation of Positive_regulation of Crh 1 0.36 0 0.35
110 INT187064 ARSD Negative_regulation of CYP19A1 1 0.22 0.7 0.35
111 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
112 INT37552 Crh Regulation of Avp 1 0.22 0 0.34
113 INT37551 Positive_regulation of Crh Regulation of Avp 1 0.38 0 0.34
114 INT37553 Crh Regulation of FDX1 1 0.03 0 0.34
115 INT59602 Crhr1 Positive_regulation of Localization of LH 1 0.25 0 0.33
116 INT30418 Crh Negative_regulation of Localization of Gh1 1 0.41 0.72 0.33
117 INT30524 Crh Regulation of Oprl1 1 0.15 0.15 0.33
118 INT82904 Crh Negative_regulation of ge 1 0.00 1.3 0.33
119 INT26196 Npy Positive_regulation of Localization of Crh 1 0.40 0 0.33
120 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.97 0.32
121 INT26071 Adarb1 Regulation of Localization of Crh 1 0.01 0.21 0.32
122 INT30420 Crh Positive_regulation of Localization of Gh1 1 0.67 0.47 0.32
123 INT107944 Crh Regulation of Adarb1 1 0.06 0 0.32
124 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31
125 INT141019 Crh Positive_regulation of Gene_expression of Pomc 1 0.20 0.1 0.31
126 INT339002 Binding of OPRD1 and GSX1 1 0.00 0 0.3
127 INT339000 Binding of LMOD1 and GSX1 1 0.01 0 0.3
128 INT126696 Binding of Crhr1 and Crh 3 0.50 0.44 0.29
129 INT74331 Crh Regulation of Transcription of Penk 1 0.40 0.25 0.29
130 INT339001 GSX1 Positive_regulation of ADCY1 1 0.01 0 0.29
131 INT74335 Penk Regulation of Transcription of Crh 1 0.40 0.25 0.29
132 INT74336 Crh Regulation of Transcription of Egr1 1 0.49 0.24 0.28
133 INT134927 CYP19A1 Positive_regulation of Gene_expression of MME 1 0.30 1.04 0.28
134 INT134930 MME Positive_regulation of Gene_expression of CYP19A1 1 0.30 1.04 0.28
135 INT74330 Crh Regulation of Transcription of Fos 1 0.49 0.24 0.28
136 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
137 INT56978 Crh Positive_regulation of Localization of Gnrh1 1 0.10 0 0.24
138 INT154523 Binding of Oxt and Crh 1 0.11 0 0.24
139 INT92205 Crh Positive_regulation of Localization of SST 1 0.30 0.87 0.21
140 INT177479 Negative_regulation of Crh Regulation of POMC 1 0.05 0.84 0.21
141 INT33560 Binding of POMC and Crh 1 0.24 0.22 0.2
142 INT62451 Il2 Regulation of Localization of Crh 1 0.53 0.19 0.2
143 INT145140 Negative_regulation of CPOX Negative_regulation of Gene_expression of CYP19A1 1 0.13 0.47 0.2
144 INT25053 Crh Regulation of PLOD1 1 0.11 0 0.19
145 INT25052 Crh Regulation of FSHR 1 0.08 0 0.19
146 INT59589 Npy Regulation of Crh 1 0.27 0 0.18
147 INT55988 POMC Positive_regulation of Negative_regulation of Crh 1 0.01 0 0.18
148 INT342647 Negative_regulation of Binding of Avp and Crh 1 0.37 0.64 0.18
149 INT59588 Npy Positive_regulation of Crh 1 0.41 0 0.18
150 INT59587 Npy Regulation of Gene_expression of Crh 1 0.27 0 0.18
151 INT33694 Crh Negative_regulation of Rhd 1 0.08 1.41 0.18
152 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
153 INT124236 Crh Regulation of Localization of BTF3 1 0.00 0.32 0.18
154 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17
155 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
156 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
157 INT304279 ETS1 Positive_regulation of MMP2 1 0.05 1.83 0.17
158 INT34351 Crh Regulation of DBI 1 0.00 0.25 0.17
159 INT304282 ETS1 Positive_regulation of Gene_expression of MMP2 1 0.05 1.83 0.17
160 INT222505 Gene_expression of Crh Negative_regulation of Gene_expression of Hpse 1 0.02 0.55 0.17
161 INT25050 Crh Negative_regulation of PLOD1 1 0.11 0 0.17
162 INT25054 Crh Negative_regulation of FSHR 1 0.07 0 0.17
163 INT17922 Positive_regulation of Crh Positive_regulation of Fos 1 0.23 0.19 0.17
164 INT5520 Negative_regulation of Dbi Negative_regulation of Gene_expression of Crh 1 0.21 0.44 0.16
165 INT5521 Oprd1 Negative_regulation of Gene_expression of Crh 1 0.11 0.43 0.16
166 INT5517 Negative_regulation of Dbi Negative_regulation of Crh 1 0.27 0.44 0.16
167 INT5522 Pomc Negative_regulation of Gene_expression of Crh 1 0.27 0.39 0.16
168 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
169 INT5516 Oprd1 Negative_regulation of Crh 1 0.15 0.43 0.16
170 INT30084 Lvp1 Regulation of Localization of Crh 1 0.00 0.14 0.16
171 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
172 INT234801 RAB3GAP1 Regulation of RAB3A 1 0.08 1.64 0.15
173 INT30421 Gnrhr Regulation of Crh 1 0.11 0.27 0.15
174 INT39154 Crh Positive_regulation of Avp 2 0.11 0.15 0.14
175 INT177480 Positive_regulation of Crh Positive_regulation of Regulation of POMC 1 0.06 0.46 0.14
176 INT293119 Agtr1a Regulation of Positive_regulation of Crh 1 0.12 0.37 0.14
177 INT293115 Agt Regulation of Positive_regulation of Crh 1 0.16 0.37 0.14
178 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
179 INT33749 Crh Positive_regulation of Localization of Agt 1 0.31 0 0.13
180 INT8162 Fos Regulation of Gene_expression of Crh 1 0.35 0.31 0.13
181 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
182 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
183 INT62748 Crh Regulation of Gal 1 0.27 0.36 0.12
184 INT168578 Crh Positive_regulation of Hrasls 1 0.06 0 0.12
185 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
186 INT156836 ETS1 Positive_regulation of Phosphorylation of MAPK7 1 0.14 0 0.1
187 INT156838 MAPK7 Positive_regulation of Phosphorylation of ETS1 1 0.13 0 0.1
188 INT5519 Dbi Negative_regulation of Crh 1 0.31 0.28 0.1
189 INT186539 Crh Regulation of Hpse 1 0.09 0.52 0.1
190 INT124235 Crh Regulation of BTF3 1 0.00 0.16 0.09
191 INT220394 MRXS5 Positive_regulation of Gene_expression of CYP19A1 1 0.00 0.89 0.09
192 INT75372 ecs Positive_regulation of Gene_expression of Crh 1 0.03 0.62 0.09
193 INT81424 Binding of Crh and Olr1000 1 0.06 0.17 0.09
194 INT25950 Ins1 Regulation of Crh 1 0.14 0.07 0.09
195 INT285070 CCL16 Positive_regulation of Gene_expression of CYP19A1 1 0.02 0.69 0.09
196 INT220412 Cpox Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.9 0.09
197 INT33471 POMC Positive_regulation of Localization of Crh 1 0.11 0 0.08
198 INT94353 Crh Negative_regulation of Positive_regulation of Dbi 1 0.03 0.14 0.08
199 INT94354 Crh Negative_regulation of Dbi 1 0.03 0.14 0.08
200 INT261262 AIS Negative_regulation of Cyp19a1 1 0.01 0.2 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for hypothalamus development. They are ordered first by their pain relevance and then by number of times they were reported in hypothalamus development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1562 Localization of Crh 499 0.81 126.74 236.68
2 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
3 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
4 INT1898 Regulation of Crh 220 0.62 61.33 102.64
5 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
6 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
7 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
8 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
9 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
10 INT16879 Binding of Crh 72 0.48 21.65 28.43
11 INT21379 Transcription of Crh 65 0.72 15.64 27.92
12 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
13 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21
14 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34
15 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73
16 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26
17 INT9751 Localization of Crhr1 26 0.78 10.47 15.69
18 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
19 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
20 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
21 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21
22 INT10597 Gene_expression of Cyp19a1 27 0.78 7.48 9.11
23 INT7572 Regulation of Crhr1 8 0.45 5.6 8.93
24 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34
25 INT5498 Positive_regulation of Positive_regulation of Crh 19 0.70 9.82 7.97
26 INT7570 Transcription of Crhr1 7 0.66 6.6 7.6
27 INT74326 Gene_expression of Crhr1 25 0.66 9.7 7.48
28 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
29 INT80161 Positive_regulation of Crhr1 13 0.67 9.66 7.33
30 INT22336 Positive_regulation of Transcription of Crh 18 0.68 4.61 6.91
31 INT9753 Positive_regulation of Localization of Crhr1 8 0.49 1.72 6.55
32 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
33 INT135760 Regulation of Gene_expression of Cyp19a1 2 0.62 1.15 5.81
34 INT22485 Negative_regulation of Positive_regulation of Crh 13 0.59 4.49 5.46
35 INT18244 Regulation of Positive_regulation of Crh 11 0.45 3.87 5.41
36 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37
37 INT145929 Regulation of Bax 20 0.60 18.12 5.35
38 INT22338 Negative_regulation of Transcription of Crh 11 0.43 2.09 5.24
39 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
40 INT18245 Negative_regulation of Localization of Crhr1 4 0.17 0.28 4.81
41 INT7568 Negative_regulation of Crhr1 8 0.43 4.63 4.77
42 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
43 INT28734 Gene_expression of Reln 7 0.74 5.76 4.33
44 INT123752 Regulation of Bax 19 0.60 16.45 4
45 INT112692 Localization of Bax 31 0.80 20.97 3.98
46 INT63441 Regulation of Transcription of Crh 9 0.60 4.51 3.9
47 INT99889 Transcription of SRD5A1 5 0.71 1.45 3.74
48 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56
49 INT127336 Positive_regulation of Transcription of Crhr1 3 0.48 3.37 3.19
50 INT28715 Negative_regulation of Regulation of Crh 7 0.43 0.97 3.06
51 INT116376 Transcription of Cyp19a1 2 0.40 0.74 3.04
52 INT133809 Negative_regulation of Gene_expression of CYP19A1 9 0.43 7.67 2.99
53 INT113277 Positive_regulation of Gene_expression of CYP19A1 13 0.69 10.23 2.97
54 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96
55 INT9752 Regulation of Localization of Crhr1 3 0.44 0.36 2.82
56 INT5510 Negative_regulation of Negative_regulation of Crh 8 0.43 1.05 2.61
57 INT22339 Positive_regulation of Negative_regulation of Crh 5 0.67 1.36 2.59
58 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
59 INT71048 Transcription of CYP19A1 11 0.72 8.74 2.24
60 INT111113 Binding of CYP19A1 15 0.36 9.17 2.12
61 INT154970 Localization of Bax 15 0.74 11.12 2.11
62 INT342803 Positive_regulation of Transcription of Cyp19a1 1 0.30 0.33 2.08
63 INT342815 Positive_regulation of Transcription of SRD5A1 1 0.49 0.33 2.04
64 INT98836 Transcription of Bax 6 0.69 5.04 1.96
65 INT81347 Regulation of Cyp19a1 7 0.40 2.1 1.94
66 INT134442 Transcription of Bax 14 0.67 7.6 1.9
67 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
68 INT134443 Binding of Bax 10 0.47 5.62 1.84
69 INT265064 Binding of Reln 1 0.02 2.7 1.83
70 INT30834 Regulation of Negative_regulation of Crh 3 0.45 0.62 1.81
71 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
72 INT142929 Regulation of Crhr2 1 0.44 1.28 1.73
73 INT265066 Positive_regulation of Reln 1 0.02 1.59 1.72
74 INT209366 Negative_regulation of GSX1 1 0.42 0.92 1.72
75 INT28735 Localization of Reln 2 0.12 1.49 1.7
76 INT10596 Positive_regulation of Cyp19a1 10 0.42 2.08 1.62
77 INT18710 Regulation of Regulation of Crh 6 0.60 0.79 1.6
78 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
79 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
80 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
81 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
82 INT127889 Regulation of Gene_expression of CYP19A1 11 0.62 6.7 1.41
83 INT159312 Regulation of Reln 4 0.43 1.79 1.4
84 INT112934 Binding of Crhr1 7 0.46 2.69 1.39
85 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
86 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
87 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
88 INT198387 Regulation of SRD5A1 2 0.60 1.29 1.26
89 INT28888 Positive_regulation of Crhr2 6 0.68 3.8 1.23
90 INT55599 Gene_expression of GSX1 3 0.65 3.72 1.23
91 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
92 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
93 INT25043 Positive_regulation of Regulation of Crh 5 0.50 1 1.06
94 INT154493 Regulation of Gene_expression of SRD5A1 3 0.45 0.58 1.03
95 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
96 INT58050 Regulation of Binding of Crh 2 0.42 0.84 0.86
97 INT90054 Regulation of Rax 3 0.25 0.8 0.85
98 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
99 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
100 INT79344 Binding of Cyp19a1 4 0.33 0.61 0.8
101 INT74324 Positive_regulation of Gene_expression of Crhr1 6 0.49 2.91 0.79
102 INT77256 Negative_regulation of Gene_expression of Crhr1 5 0.40 2.52 0.77
103 INT209367 Binding of GSX1 1 0.47 0.56 0.76
104 INT7567 Negative_regulation of Transcription of Crhr1 1 0.37 0.48 0.71
105 INT161339 Localization of Cyp19a1 1 0.73 1.32 0.71
106 INT209368 Positive_regulation of GSX1 1 0.49 0.51 0.67
107 INT28889 Transcription of Crhr2 2 0.64 1.13 0.66
108 INT7563 Regulation of Transcription of Crhr1 1 0.17 0.59 0.59
109 INT171105 Positive_regulation of Positive_regulation of CYP19A1 5 0.39 4.02 0.58
110 INT55598 Regulation of GSX1 1 0.44 0.95 0.55
111 INT353896 Negative_regulation of Phosphorylation of Cyp19a1 1 0.22 0.47 0.55
112 INT55600 Regulation of Gene_expression of GSX1 1 0.44 0.96 0.55
113 INT353893 Phosphorylation of Cyp19a1 1 0.31 0.46 0.55
114 INT176242 Binding of Bax 10 0.42 10.18 0.52
115 INT342811 Positive_regulation of Gene_expression of SRD5A1 1 0.45 0.22 0.5
116 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
117 INT71046 Localization of CYP19A1 2 0.78 1.38 0.48
118 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
119 INT187717 Regulation of Negative_regulation of CYP19A1 11 0.42 2.85 0.45
120 INT127890 Positive_regulation of Negative_regulation of CYP19A1 6 0.50 1.41 0.45
121 INT148784 Negative_regulation of Crhr2 2 0.40 0.76 0.42
122 INT84915 Negative_regulation of Gene_expression of Cyp19a1 2 0.15 1.29 0.42
123 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
124 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
125 INT83897 Protein_catabolism of Crh 2 0.86 1.75 0.39
126 INT156860 Gene_expression of ETS1 2 0.30 0.84 0.37
127 INT144599 Gene_expression of Crhr2 3 0.49 2.16 0.36
128 INT181122 Positive_regulation of Gene_expression of Cyp19a1 1 0.02 0.68 0.36
129 INT121505 Regulation of Regulation of Crhr1 1 0.43 0.33 0.35
130 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
131 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
132 INT153296 Regulation of Gene_expression of Crhr1 2 0.39 0.72 0.34
133 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
134 INT209323 Positive_regulation of Transcription of CYP19A1 5 0.32 4.22 0.33
135 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
136 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
137 INT102992 Regulation of Negative_regulation of SRD5A1 4 0.60 3.59 0.29
138 INT326154 Regulation of ETS1 1 0.07 1.69 0.29
139 INT176492 Positive_regulation of Gene_expression of ETS1 1 0.09 0.84 0.28
140 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
141 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
142 INT126794 Binding of SRD5A1 2 0.36 3.26 0.22
143 INT159314 Positive_regulation of Gene_expression of Reln 1 0.44 0.47 0.2
144 INT175360 Regulation of Transcription of CYP19A1 1 0.04 1 0.19
145 INT55986 Positive_regulation of Binding of Crh 1 0.48 0.76 0.19
146 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
147 INT112935 Binding of Crhr2 1 0.32 0.33 0.17
148 INT279598 Gene_expression of Rax 3 0.07 2.91 0.15
149 INT194032 Binding of Rax 3 0.03 0.13 0.14
150 INT163408 Negative_regulation of Gene_expression of Crhr2 2 0.27 1.56 0.13
151 INT92090 Negative_regulation of Protein_catabolism of Crh 1 0.04 0.99 0.12
152 INT236875 Localization of SRD5A1 2 0.73 0.8 0.11
153 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
154 INT156854 Phosphorylation of ETS1 1 0.24 0 0.1
155 INT355406 Regulation of Gene_expression of Rax 1 0.01 1.63 0.1
156 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
157 INT156847 Negative_regulation of ETS1 1 0.16 0 0.09
158 INT265068 Transcription of Reln 1 0.03 0.07 0.09
159 INT156863 Negative_regulation of Gene_expression of ETS1 1 0.22 0 0.09
160 INT12282 Localization of Rax 1 0.68 0.34 0.08
161 INT165756 Positive_regulation of Gene_expression of Crhr2 1 0.31 0.62 0.07
162 INT165757 Positive_regulation of Positive_regulation of Crhr1 1 0.29 0.6 0.07
163 INT307466 Positive_regulation of Phosphorylation of Bax 1 0.15 0.76 0.07
164 INT165755 Regulation of Gene_expression of Crhr2 1 0.28 0.62 0.07
165 INT236876 Negative_regulation of Localization of SRD5A1 1 0.41 0.81 0.06
166 INT225725 Phosphorylation of RAB3GAP1 1 0.04 0.33 0.06
167 INT225724 Positive_regulation of RAB3GAP1 1 0.03 0.34 0.06
168 INT355401 Transcription of Rax 1 0.02 0.59 0.05
169 INT268622 Regulation of Negative_regulation of Bax 1 0.12 0.81 0.05
170 INT187718 Negative_regulation of Positive_regulation of CYP19A1 1 0.33 0.61 0.05
171 INT355405 Regulation of Transcription of Rax 1 0.01 0.5 0.05
172 INT220802 Binding of LEF1 7 0.36 3.86 0.04
173 INT289116 Positive_regulation of Localization of LEF1 2 0.22 1.19 0.04
174 INT309494 Negative_regulation of Binding of Bax 2 0.38 1.31 0.04
175 INT289110 Localization of LEF1 2 0.32 1.19 0.04
176 INT260297 Binding of ETS1 1 0.08 0.68 0.04
177 INT340387 Regulation of Positive_regulation of Bax 1 0.27 0.61 0.04
178 INT340390 Regulation of Binding of Bax 1 0.54 0.59 0.04
179 INT123525 Phosphorylation of Bax 3 0.41 1.18 0.03
180 INT176247 Positive_regulation of Phosphorylation of Bax 1 0.12 0.42 0.03
181 INT187720 Negative_regulation of Negative_regulation of CYP19A1 5 0.34 0.99 0
182 INT178534 Positive_regulation of SRD5A1 2 0.44 1.23 0
183 INT289127 Positive_regulation of LEF1 2 0.22 0.76 0
184 INT236869 Negative_regulation of Negative_regulation of SRD5A1 2 0.41 2.68 0
185 INT330041 Positive_regulation of Regulation of Bax 1 0.29 1.63 0
186 INT187725 Positive_regulation of Localization of CYP19A1 1 0.39 0.23 0
187 INT333213 Regulation of Transcription of Bax 1 0.11 0.14 0
188 INT341821 Positive_regulation of Gene_expression of Rax 1 0.05 0.38 0
189 INT337456 Positive_regulation of Binding of LEF1 1 0.22 0 0
190 INT341822 Positive_regulation of Rax 1 0.05 0.38 0
191 INT234916 Gene_expression of Lef1 1 0.04 0.25 0
192 INT213932 Negative_regulation of Negative_regulation of Cyp19a1 1 0.31 0.7 0
193 INT194353 Negative_regulation of Binding of Cyp19a1 1 0.15 0 0
194 INT355389 Negative_regulation of Gene_expression of Rax 1 0.01 0.16 0
195 INT145141 Negative_regulation of Transcription of CYP19A1 1 0.59 0.3 0
196 INT331746 Regulation of Binding of Rax 1 0.04 0.06 0
197 INT289129 Positive_regulation of Gene_expression of LEF1 1 0.13 0.76 0
198 INT187719 Negative_regulation of Localization of CYP19A1 1 0.33 0.78 0
199 INT322640 Positive_regulation of Binding of Bax 1 0.12 0.88 0
200 INT222306 Negative_regulation of Binding of CYP19A1 1 0.20 1.04 0
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