GO:0021879

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Name forebrain neuron differentiation
Categary Process
Go Slim No
Go Link GO:0021879
Unique Molecular Interactions 33
Total Molecular Interactions 39
Total Single Events 241
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for forebrain neuron differentiation. They are ordered first by their pain relevance and then by number of times they were reported for forebrain neuron differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
2 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
3 INT302369 Binding of Arx and Dlx1 1 0.34 0 0.43
4 INT302371 Dlx1 Regulation of Gene_expression of Arx 1 0.28 0 0.35
5 INT342164 Binding of Csf2 and Nkx2-1 1 0.01 0.52 0.26
6 INT302367 Dlx2 Regulation of Gene_expression of Arx 1 0.59 0.23 0.22
7 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
8 INT310494 Gene_expression of Dlx2 Positive_regulation of Fate1 1 0.04 0.1 0.18
9 INT309372 Lhx5 Positive_regulation of Gene_expression of Pax2 1 0.09 0.07 0.11
10 INT201173 Sox2 Positive_regulation of Localization of Ryr2 1 0.40 0.9 0.07
11 INT201172 Sox2 Positive_regulation of Localization of Ca2 1 0.47 0.9 0.07
12 INT213562 Ctnnd2 Regulation of Gene_expression of Sox2 1 0.35 0.07 0.05
13 INT289101 Binding of KCNA1 and LEF1 1 0.00 2.58 0.03
14 INT337402 LEF1 Positive_regulation of E2F1 1 0.11 0 0
15 INT183648 Binding of Lef1 and Ctnnd2 1 0.07 1.05 0
16 INT337415 Negative_regulation of MIR203 Positive_regulation of Positive_regulation of LEF1 1 0.03 0.25 0
17 INT197309 Ascl1 Regulation of Neurod1 1 0.01 0.13 0
18 INT337405 MIR203 Regulation of LEF1 1 0.02 0.31 0
19 INT337411 Negative_regulation of MIR203 Positive_regulation of Gene_expression of LEF1 1 0.04 0.25 0
20 INT289102 KCNA1 Negative_regulation of Gene_expression of LEF1 1 0.00 0.44 0
21 INT289098 KCNA1 Regulation of LEF1 1 0.00 0.67 0
22 INT337417 MIR203 Negative_regulation of LEF1 1 0.04 0.57 0
23 INT220822 Binding of Myc and LEF1 1 0.26 0.08 0
24 INT242102 Nkx2-1 Regulation of Gene_expression of Ttf1 1 0.00 1.55 0
25 INT220766 Binding of MAX and LEF1 1 0.40 0.08 0
26 INT185268 Binding of Fgf2 and Sox1 1 0.19 0 0
27 INT185272 Binding of Egf and Sox1 1 0.21 0 0
28 INT185267 Egf Negative_regulation of Gene_expression of Dlx2 1 0.12 0.15 0
29 INT197314 Hes5 Regulation of Ascl1 1 0.00 0.14 0
30 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
31 INT197307 Ascl1 Regulation of Neurod6 1 0.00 0.13 0
32 INT185266 Egf Regulation of Gene_expression of Dlx2 1 0.12 0.07 0
33 INT289100 KCNA1 Regulation of Gene_expression of LEF1 1 0.00 0.68 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for forebrain neuron differentiation. They are ordered first by their pain relevance and then by number of times they were reported in forebrain neuron differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT185252 Gene_expression of Dlx2 7 0.71 8.8 6.24
2 INT302340 Positive_regulation of Gene_expression of Dlx2 2 0.64 3.43 2.15
3 INT158442 Gene_expression of Nkx2-1 21 0.59 8.47 1.99
4 INT244735 Gene_expression of Ascl1 12 0.58 2.48 1.54
5 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
6 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
7 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
8 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
9 INT294805 Gene_expression of Dlx1 4 0.70 0.45 0.81
10 INT185244 Gene_expression of Sox2 27 0.65 4.71 0.61
11 INT185255 Positive_regulation of Sox2 3 0.26 1.22 0.42
12 INT302352 Positive_regulation of Binding of Dlx1 1 0.45 0 0.4
13 INT302357 Binding of Dlx1 1 0.33 0 0.39
14 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
15 INT201143 Regulation of Sox2 6 0.44 2.71 0.26
16 INT310477 Positive_regulation of Dlx2 1 0.46 0.47 0.23
17 INT310471 Regulation of Ascl1 1 0.34 0.19 0.22
18 INT310492 Transcription of Dlx2 1 0.63 0.09 0.18
19 INT310468 Regulation of Gene_expression of Dlx2 1 0.42 0.1 0.18
20 INT310462 Positive_regulation of Gene_expression of Ascl1 1 0.37 0.52 0.17
21 INT294809 Positive_regulation of Gene_expression of Dlx1 2 0.37 0.21 0.16
22 INT310469 Negative_regulation of Gene_expression of Dlx2 1 0.39 0.66 0.16
23 INT310488 Binding of Ascl1 1 0.28 0.25 0.16
24 INT185243 Gene_expression of Sox1 6 0.61 0.91 0.12
25 INT201144 Regulation of Gene_expression of Sox2 3 0.44 0.82 0.11
26 INT309345 Gene_expression of Lhx5 1 0.25 0.06 0.11
27 INT310465 Binding of Dlx2 1 0.34 0.33 0.11
28 INT201140 Transcription of Sox2 4 0.67 1.31 0.1
29 INT310484 Positive_regulation of Ascl1 1 0.37 0.47 0.09
30 INT309350 Negative_regulation of Lhx5 1 0.14 0.07 0.08
31 INT185257 Positive_regulation of Sox1 1 0.39 0 0.05
32 INT185260 Positive_regulation of Positive_regulation of Sox2 1 0.15 0 0.05
33 INT220802 Binding of LEF1 7 0.36 3.86 0.04
34 INT213537 Positive_regulation of Gene_expression of Sox2 3 0.48 1.34 0.04
35 INT289116 Positive_regulation of Localization of LEF1 2 0.22 1.19 0.04
36 INT289110 Localization of LEF1 2 0.32 1.19 0.04
37 INT213528 Negative_regulation of Gene_expression of Sox2 1 0.30 0.07 0.04
38 INT201142 Negative_regulation of Sox2 4 0.57 0.59 0
39 INT201141 Binding of Sox2 3 0.36 0.53 0
40 INT289127 Positive_regulation of LEF1 2 0.22 0.76 0
41 INT337456 Positive_regulation of Binding of LEF1 1 0.22 0 0
42 INT242099 Binding of Nkx2-1 1 0.02 1.15 0
43 INT185259 Negative_regulation of Gene_expression of Sox1 1 0.34 0 0
44 INT234916 Gene_expression of Lef1 1 0.04 0.25 0
45 INT289129 Positive_regulation of Gene_expression of LEF1 1 0.13 0.76 0
46 INT201146 Negative_regulation of Binding of Sox2 1 0.41 0.28 0
47 INT337461 Positive_regulation of Transcription of LEF1 1 0.22 0.26 0
48 INT201139 Localization of Sox2 1 0.73 0.15 0
49 INT289108 Negative_regulation of Transcription of LEF1 1 0.11 0.32 0
50 INT220775 Binding of Lef1 1 0.20 0.06 0
51 INT185249 Positive_regulation of Gene_expression of Sox1 1 0.39 0 0
52 INT289124 Negative_regulation of Positive_regulation of LEF1 1 0.11 0.34 0
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