GO:0021884

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Name forebrain neuron development
Categary Process
Go Slim No
Go Link GO:0021884
Unique Molecular Interactions 43
Total Molecular Interactions 60
Total Single Events 187
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for forebrain neuron development. They are ordered first by their pain relevance and then by number of times they were reported for forebrain neuron development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
2 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
3 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
4 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
5 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
6 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
7 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
8 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
9 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
10 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
11 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
12 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
13 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
14 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
15 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
16 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
17 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
18 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
19 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
20 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
21 INT173356 Gnaq Positive_regulation of CDK20 1 0.06 0 0.37
22 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
23 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
24 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
25 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
26 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
27 INT173358 Gnaq Positive_regulation of SMPD1 1 0.01 0.13 0.23
28 INT173357 Gnaq Positive_regulation of PRKCA 1 0.01 0 0.22
29 INT72019 Binding of Gnaq and Ptprg 1 0.01 0 0.21
30 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
31 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
32 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
33 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
34 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
35 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
36 INT227593 Gnaq Negative_regulation of GLUL 1 0.01 0 0.06
37 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
38 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
39 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
40 INT245820 Binding of Sp1 and Tfap2a 1 0.03 0.64 0
41 INT245828 Binding of VEGFA and Tfap2a 1 0.01 0.64 0
42 INT185268 Binding of Fgf2 and Sox1 1 0.19 0 0
43 INT185272 Binding of Egf and Sox1 1 0.21 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for forebrain neuron development. They are ordered first by their pain relevance and then by number of times they were reported in forebrain neuron development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
2 INT72000 Gene_expression of Gnaq 17 0.75 3.12 5.48
3 INT112880 Positive_regulation of Gnaq 17 0.49 1.97 1.95
4 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
5 INT110189 Regulation of Gnaq 3 0.02 0.26 1.63
6 INT71999 Negative_regulation of Gene_expression of Gnaq 3 0.41 0.08 1.56
7 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
8 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
9 INT110188 Regulation of Gene_expression of Gnaq 2 0.25 0.85 1.22
10 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
11 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
12 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
13 INT72002 Negative_regulation of Gnaq 7 0.35 0.2 1.02
14 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
15 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
16 INT110187 Regulation of Regulation of Gnaq 1 0.00 0.07 0.82
17 INT141915 Positive_regulation of Gene_expression of Gnaq 3 0.19 1.31 0.76
18 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
19 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
20 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
21 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
22 INT112881 Positive_regulation of Positive_regulation of Gnaq 2 0.49 0.86 0.54
23 INT141919 Positive_regulation of Transcription of Gnaq 1 0.21 1.05 0.49
24 INT141912 Negative_regulation of Transcription of Gnaq 1 0.18 1.07 0.49
25 INT141917 Transcription of Gnaq 1 0.29 1.05 0.49
26 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
27 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
28 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
29 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34
30 INT149315 Binding of Gnaq 2 0.04 0 0.26
31 INT250836 Binding of Fgf8 3 0.35 0.66 0.24
32 INT250833 Localization of Fgf8 1 0.74 0.46 0.21
33 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21
34 INT162939 Binding of Tfap2a 1 0.26 0.34 0.17
35 INT162940 Negative_regulation of Tfap2a 1 0.32 0.34 0.17
36 INT162941 Negative_regulation of Binding of Tfap2a 1 0.32 0.34 0.17
37 INT250835 Positive_regulation of Fgf8 1 0.50 0.42 0.14
38 INT185243 Gene_expression of Sox1 6 0.61 0.91 0.12
39 INT272710 Phosphorylation of Gnaq 1 0.09 0.12 0.12
40 INT185257 Positive_regulation of Sox1 1 0.39 0 0.05
41 INT227570 Localization of Gnaq 1 0.07 0 0.04
42 INT227569 Negative_regulation of Positive_regulation of Gnaq 1 0.04 0.08 0.04
43 INT185259 Negative_regulation of Gene_expression of Sox1 1 0.34 0 0
44 INT250830 Regulation of Protein_catabolism of Fgf8 1 0.45 0.08 0
45 INT311651 Positive_regulation of Fgf8 1 0.46 0.26 0
46 INT250846 Positive_regulation of Protein_catabolism of Fgf8 1 0.50 0.07 0
47 INT311630 Negative_regulation of Tfap2a 1 0.34 0.23 0
48 INT185249 Positive_regulation of Gene_expression of Sox1 1 0.39 0 0
49 INT319128 Positive_regulation of Binding of Tfap2a 1 0.23 0.5 0
50 INT311626 Negative_regulation of Gene_expression of Tfap2a 1 0.34 0.29 0
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