GO:0021987

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Name cerebral cortex development
Categary Process
Go Slim No
Go Link GO:0021987
Unique Molecular Interactions 765
Total Molecular Interactions 1089
Total Single Events 11681
Pain Genes Associated 51

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cerebral cortex development. They are ordered first by their pain relevance and then by number of times they were reported for cerebral cortex development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
2 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
3 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
4 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
5 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
6 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
7 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
8 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
9 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
10 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
11 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
12 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
13 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
14 INT130284 Ins1 Negative_regulation of Gene_expression of Npy 1 0.32 0.1 2.47
15 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37
16 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
17 INT91860 Npy Regulation of Npy1r 2 0.28 1.13 2.24
18 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
19 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
20 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
21 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
22 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
23 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
24 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
25 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
26 INT190981 Binding of Npy and Scn2a1 1 0.10 0 1.75
27 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
28 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
29 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
30 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61
31 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
32 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
33 INT7796 Akr1d1 Regulation of Npy 1 0.03 0 1.57
34 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
35 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
36 INT40887 Penk Regulation of Th 1 0.04 0 1.53
37 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
38 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
39 INT29127 Npy Positive_regulation of LH 1 0.47 0 1.45
40 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
41 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
42 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
43 INT73377 Npy Regulation of Adarb1 2 0.03 0.15 1.38
44 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 0.13 0.15 1.36
45 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
46 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
47 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
48 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
49 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
50 INT50386 Bdnf Regulation of Npy 1 0.21 0.47 1.24
51 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
52 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
53 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
54 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
55 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
56 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
57 INT106069 TH Positive_regulation of Th 1 0.07 0.16 1.14
58 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
59 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11
60 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
61 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1
62 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
63 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
64 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
65 INT31547 Binding of Th and Vip 1 0.31 0 1.08
66 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
67 INT85718 pcp Regulation of Npy 1 0.03 0 1.07
68 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
69 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
70 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
71 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
72 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
73 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
74 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04
75 INT41175 Adra2a Regulation of Th 1 0.59 0 1.04
76 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
77 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
78 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
79 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
80 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
81 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
82 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
83 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
84 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
85 INT31548 Binding of Th and Dbh 1 0.35 0 0.98
86 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
87 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98
88 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
89 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
90 INT36186 Npy Positive_regulation of Localization of Gnrh1 4 0.75 0.09 0.96
91 INT116185 Npy Negative_regulation of Positive_regulation of Npy1r 1 0.41 0.32 0.96
92 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
93 INT130282 Cyp3a23/3a1 Positive_regulation of Gene_expression of Npy 1 0.15 0 0.94
94 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93
95 INT9014 Binding of Npy and Penk 1 0.37 0 0.93
96 INT7794 Ptgdr Regulation of Npy 1 0.11 0 0.92
97 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
98 INT136172 NPY Negative_regulation of Positive_regulation of Drd1a 1 0.21 0 0.91
99 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
100 INT48341 Negative_regulation of Pde8a Regulation of Ahsg 1 0.22 0 0.9
101 INT48342 Pde8a Regulation of Ahsg 1 0.24 0 0.9
102 INT137563 Ghrl Positive_regulation of Gene_expression of Npy 1 0.59 0 0.87
103 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87
104 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87
105 INT66333 Fgf2 Negative_regulation of Positive_regulation of Npy 1 0.20 0.17 0.85
106 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
107 INT48751 Binding of Nqo1 and Npy 1 0.28 0 0.82
108 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
109 INT128943 Pomc Regulation of Npy 1 0.23 0.61 0.81
110 INT63940 Negative_regulation of Vta1 Positive_regulation of Th 1 0.13 0 0.81
111 INT100559 Binding of Grin1 and LOC502940 1 0.13 0.61 0.8
112 INT245564 Runx3 Negative_regulation of Ntrk2 3 0.61 1.61 0.79
113 INT130281 Dexi Positive_regulation of Gene_expression of Npy 1 0.08 0 0.79
114 INT130283 Cyp3a23/3a1 Positive_regulation of Transcription of Npy 1 0.10 0 0.79
115 INT130285 Dexi Positive_regulation of Transcription of Npy 1 0.07 0 0.79
116 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
117 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78
118 INT29128 Negative_regulation of Npy Positive_regulation of LH 1 0.44 0 0.77
119 INT215630 Fig4 Regulation of Npy 1 0.01 0.26 0.76
120 INT329120 Binding of KCNA1 and CNTNAP2 1 0.09 1.23 0.75
121 INT13344 Binding of Npy and Adarb1 2 0.02 0.41 0.73
122 INT329119 Binding of CNTN2 and CNTNAP2 1 0.08 2.41 0.73
123 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
124 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
125 INT296290 Binding of Car1 and Grin1 1 0.11 0.32 0.72
126 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
127 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
128 INT14621 Gal Regulation of Npy 1 0.30 0 0.7
129 INT351375 Mir470 Negative_regulation of Ntrk2 1 0.01 1.54 0.7
130 INT102344 Grin1 Regulation of Localization of C3orf52 1 0.00 0 0.68
131 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
132 INT12759 Npy Regulation of Localization of Calca 1 0.26 0.08 0.68
133 INT161186 Bdnf Regulation of Gene_expression of Ntrk2 1 0.44 1.05 0.68
134 INT8980 Gal Regulation of PLCB1 1 0.18 0.13 0.68
135 INT114036 Binding of Grin1 and Psd 1 0.24 0.45 0.68
136 INT142244 Positive_regulation of Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67
137 INT142243 Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67
138 INT161184 NMS Positive_regulation of Gene_expression of Ntrk2 1 0.55 1.3 0.67
139 INT335054 LPL Positive_regulation of Localization of VLDLR 1 0.04 1.48 0.67
140 INT15322 Binding of Npy and Cck 1 0.26 0.45 0.66
141 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66
142 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66
143 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
144 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
145 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
146 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
147 INT7792 Akr1d1 Regulation of Gene_expression of Npy 1 0.02 0 0.65
148 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
149 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
150 INT63655 Binding of NPY and TAC1 1 0.39 0.17 0.64
151 INT7958 LOC686180 Positive_regulation of Gene_expression of Th 1 0.02 0 0.64
152 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63
153 INT73381 Npy5r Positive_regulation of Positive_regulation of Npy 1 0.12 0 0.63
154 INT236003 Binding of HTR1A and Grin1 1 0.01 0.7 0.63
155 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
156 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
157 INT284089 Binding of NTRK2 and SERPINE1 1 0.27 0.73 0.61
158 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
159 INT90119 Ntrk2 Regulation of Gene_expression of Nfkb1 1 0.01 0.27 0.6
160 INT79740 Ntf3 Regulation of Positive_regulation of Ntrk2 1 0.28 0 0.6
161 INT90115 Ntrk2 Regulation of Jun 1 0.01 0.27 0.57
162 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
163 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57
164 INT298271 Proc Negative_regulation of Gene_expression of Ntrk2 1 0.01 0.79 0.56
165 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56
166 INT298278 Runx1 Negative_regulation of Gene_expression of Ntrk2 1 0.44 0.8 0.56
167 INT261481 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.02 0.21 0.56
168 INT95895 Sigmar1 Regulation of Positive_regulation of Npy 1 0.18 0 0.55
169 INT263776 Grin1 Positive_regulation of Ltp 2 0.17 0.17 0.54
170 INT113627 Binding of NPY and RHD 1 0.04 0 0.54
171 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
172 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
173 INT193554 Ntrk2 Positive_regulation of Positive_regulation of Ephb1 1 0.01 0.73 0.52
174 INT160061 Positive_regulation of Syt17 Positive_regulation of Localization of Npy 1 0.09 0 0.51
175 INT76068 Gal Positive_regulation of Grin1 1 0.34 0 0.51
176 INT134533 Binding of Ntrk2 and Psds1 1 0.01 0 0.5
177 INT66336 Fgf2 Regulation of Gene_expression of Npy 1 0.12 0.09 0.5
178 INT160062 Syt17 Positive_regulation of Localization of Npy 1 0.09 0 0.5
179 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
180 INT250080 Grin2b Positive_regulation of Ltp 1 0.22 0.19 0.49
181 INT250082 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Grin1 1 0.03 0.08 0.49
182 INT250081 Grin2a Positive_regulation of Ltp 1 0.20 0.14 0.48
183 INT283736 Tbs1 Positive_regulation of Grin1 1 0.04 0 0.48
184 INT71318 Grik4 Positive_regulation of Localization of Npy 1 0.05 0 0.47
185 INT71317 Grip2 Positive_regulation of Localization of Npy 1 0.09 0 0.47
186 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
187 INT7957 Calca Positive_regulation of Gene_expression of Th 1 0.39 0 0.47
188 INT281982 Cyp3a23/3a1 Negative_regulation of Gene_expression of MDK 1 0.00 0.67 0.47
189 INT26448 Adra2a Regulation of Positive_regulation of Npy 1 0.06 0 0.46
190 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
191 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
192 INT128043 Positive_regulation of Ntrk2 Positive_regulation of Phosphorylation of Trib3 1 0.07 0.34 0.45
193 INT127392 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin1 1 0.08 0.71 0.45
194 INT127397 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin1 1 0.01 0.71 0.45
195 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
196 INT250083 Positive_regulation of Ltp Positive_regulation of Grin1 1 0.03 0 0.45
197 INT127394 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin2a 1 0.01 0.71 0.45
198 INT127396 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin2a 1 0.00 0.71 0.45
199 INT154592 Binding of Ntrk2 and Positive_regulation of Gene_expression of Kcna3 1 0.11 0.16 0.44
200 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44

Single Events

The table below shows the top 100 pain related interactions that have been reported for cerebral cortex development. They are ordered first by their pain relevance and then by number of times they were reported in cerebral cortex development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
2 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
3 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21
4 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
5 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
6 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
7 INT7327 Regulation of Th 164 0.62 29.67 110.14
8 INT5283 Positive_regulation of Npy 191 0.70 66.77 109.2
9 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
10 INT6107 Localization of Npy 180 0.81 26.76 81.67
11 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
12 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
13 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
14 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
15 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
16 INT5338 Regulation of Npy 92 0.62 25.54 51.24
17 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
18 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
19 INT5337 Negative_regulation of Npy 87 0.59 19.6 46.75
20 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
21 INT350 Localization of Th 79 0.80 10.26 41.17
22 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
23 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
24 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
25 INT11246 Binding of Grin1 65 0.48 14.53 36.93
26 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
27 INT7326 Transcription of Th 83 0.72 13.5 35.33
28 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
29 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
30 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
31 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
32 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
33 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
34 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
35 INT17925 Transcription of Npy 53 0.72 15.75 25.56
36 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
37 INT12424 Binding of Npy 48 0.48 8.23 24.26
38 INT8380 Positive_regulation of Gene_expression of Npy 49 0.70 19.62 24.13
39 INT4781 Gene_expression of TH 68 0.73 26.92 24.01
40 INT15458 Gene_expression of NPY 50 0.76 22.67 23.03
41 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78
42 INT13643 Phosphorylation of Th 20 0.82 1.9 20.97
43 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
44 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59
45 INT11243 Localization of NPY 33 0.78 11.18 19.24
46 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
47 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
48 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
49 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23
50 INT16624 Localization of Grin1 38 0.79 8.46 17.15
51 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
52 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
53 INT7667 Regulation of Gene_expression of Npy 28 0.60 16.65 16.11
54 INT13716 Positive_regulation of TH 33 0.68 19.11 16
55 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
56 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
57 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
58 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
59 INT12281 Negative_regulation of Gene_expression of Npy 23 0.59 7.45 13.41
60 INT65172 Negative_regulation of Ntrk2 35 0.59 9.89 13.08
61 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
62 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
63 INT8086 Negative_regulation of Localization of Npy 24 0.59 3.31 12.76
64 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
65 INT31368 Positive_regulation of Positive_regulation of Th 19 0.51 2.2 12.68
66 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
67 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
68 INT112103 Binding of Grin1 28 0.48 4.21 12.08
69 INT23254 Positive_regulation of Localization of Npy 27 0.65 3.01 11.98
70 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
71 INT15238 Positive_regulation of NPY 24 0.67 11.86 11.26
72 INT141 Binding of Th 21 0.48 3.53 11.04
73 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
74 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
75 INT48496 Regulation of Transcription of Th 16 0.54 2.29 10.02
76 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
77 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
78 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
79 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
80 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
81 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21
82 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
83 INT121987 Phosphorylation of Grin1 11 0.80 4.73 8.88
84 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75
85 INT47682 Transcription of Ntrk2 19 0.69 6.32 8.6
86 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
87 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
88 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
89 INT5340 Negative_regulation of Positive_regulation of Npy 12 0.55 3.83 8.23
90 INT5339 Positive_regulation of Positive_regulation of Npy 13 0.68 4.5 8.15
91 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08
92 INT7588 Regulation of NPY 13 0.44 6.97 7.97
93 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
94 INT48314 Gene_expression of NTRK2 17 0.75 7.84 7.83
95 INT26643 Negative_regulation of Positive_regulation of Th 12 0.59 1.26 7.74
96 INT135113 Localization of Grin1 18 0.73 3.73 7.69
97 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
98 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33
99 INT7624 Positive_regulation of Regulation of Th 7 0.50 2.41 7
100 INT47691 Positive_regulation of Gene_expression of Ntrk2 17 0.62 13.64 6.96
101 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88
102 INT8087 Regulation of Localization of Npy 16 0.45 2.41 6.81
103 INT245173 Gene_expression of MDK 81 0.49 51.08 6.78
104 INT3506 Localization of TH 12 0.81 0.78 6.66
105 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
106 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41
107 INT47681 Regulation of Ntrk2 17 0.62 3.61 6.31
108 INT53773 Positive_regulation of Transcription of Npy 11 0.70 3.75 6.29
109 INT7569 Positive_regulation of Transcription of Th 19 0.70 2.6 6.17
110 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
111 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
112 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
113 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
114 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
115 INT51239 Negative_regulation of Transcription of Npy 9 0.57 2.85 5.87
116 INT67693 Binding of Grin2a 9 0.38 1.74 5.68
117 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
118 INT106552 Positive_regulation of Gene_expression of Ntrk2 19 0.68 9.72 5.51
119 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
120 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
121 INT30317 Regulation of TH 14 0.43 7.27 5.38
122 INT135473 Negative_regulation of Gene_expression of Grin1 14 0.47 5.47 5.36
123 INT145929 Regulation of Bax 20 0.60 18.12 5.35
124 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
125 INT107103 Negative_regulation of Ntrk2 21 0.59 10.38 5.28
126 INT7623 Regulation of Regulation of Th 11 0.44 1.31 5.16
127 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
128 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
129 INT106555 Binding of Ntrk2 15 0.48 6.31 5.05
130 INT40620 Regulation of Positive_regulation of Th 9 0.45 2.45 4.69
131 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
132 INT68216 Binding of NF1 40 0.48 51.24 4.59
133 INT14714 Negative_regulation of NPY 10 0.58 4.41 4.52
134 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
135 INT65056 Binding of Ntrk2 20 0.36 3.72 4.42
136 INT93035 Negative_regulation of Transcription of Grin1 6 0.41 2.29 4.39
137 INT18371 Regulation of Positive_regulation of Npy 8 0.60 2.49 4.38
138 INT28734 Gene_expression of Reln 7 0.74 5.76 4.33
139 INT111404 Regulation of Positive_regulation of Grin1 5 0.56 2.49 4.31
140 INT122882 Regulation of Ntrk2 13 0.62 9.7 4.3
141 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
142 INT9349 Gene_expression of BBS2 15 0.49 12.77 4.22
143 INT30165 Positive_regulation of Phosphorylation of Th 8 0.56 0.75 4.22
144 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
145 INT47686 Regulation of Gene_expression of Ntrk2 5 0.44 5.24 4.14
146 INT115354 Regulation of Binding of Grin1 2 0.43 1.15 4.08
147 INT123752 Regulation of Bax 19 0.60 16.45 4
148 INT112692 Localization of Bax 31 0.80 20.97 3.98
149 INT200047 Negative_regulation of Gene_expression of Ntrk2 8 0.56 10.78 3.95
150 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
151 INT103999 Positive_regulation of Phosphorylation of Grin2a 5 0.38 3.12 3.94
152 INT77823 Negative_regulation of Negative_regulation of Th 9 0.59 1.56 3.79
153 INT24366 Positive_regulation of Localization of NPY 4 0.50 4.01 3.79
154 INT92516 Positive_regulation of Gene_expression of Grin1 8 0.45 2.53 3.77
155 INT99889 Transcription of SRD5A1 5 0.71 1.45 3.74
156 INT84593 Positive_regulation of Binding of Grin1 6 0.48 2.74 3.72
157 INT67248 Gene_expression of TACC2 12 0.50 13.51 3.65
158 INT134527 Phosphorylation of Ntrk2 7 0.69 3.72 3.65
159 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
160 INT15930 Positive_regulation of Ptprs 8 0.67 7.02 3.48
161 INT132888 Negative_regulation of Phosphorylation of Grin1 3 0.57 1.18 3.43
162 INT24337 Positive_regulation of Regulation of Npy 5 0.50 2.8 3.4
163 INT30166 Regulation of Phosphorylation of Th 4 0.50 0.52 3.33
164 INT37601 Negative_regulation of Ptprs 8 0.42 3.7 3.29
165 INT24296 Binding of NPY 6 0.48 2.03 3.23
166 INT132887 Positive_regulation of Phosphorylation of Grin1 3 0.49 1.73 3.08
167 INT90611 Positive_regulation of Positive_regulation of Grin2a 4 0.63 1.89 3
168 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96
169 INT329148 Gene_expression of CNTNAP2 17 0.76 6 2.95
170 INT4782 Positive_regulation of Gene_expression of TH 12 0.47 7.36 2.95
171 INT142237 Phosphorylation of Ntrk2 8 0.82 2.24 2.82
172 INT280459 Regulation of Gene_expression of Ntrk2 13 0.62 8.48 2.71
173 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
174 INT190280 Gene_expression of DICER1 12 0.65 9.54 2.67
175 INT13904 Transcription of NPY 6 0.67 1.57 2.66
176 INT281978 Regulation of MDK 1 0.30 5.9 2.66
177 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
178 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
179 INT101401 Positive_regulation of Transcription of Grin1 6 0.67 2.45 2.6
180 INT106066 Negative_regulation of Positive_regulation of TH 1 0.18 0.22 2.6
181 INT106068 Positive_regulation of Positive_regulation of TH 1 0.21 0.22 2.59
182 INT132685 Negative_regulation of NTRK2 4 0.42 2.89 2.58
183 INT105730 Localization of Grin2a 7 0.67 0.64 2.56
184 INT4704 Positive_regulation of Negative_regulation of Th 4 0.50 0.06 2.56
185 INT199798 Positive_regulation of BBS2 2 0.50 5.85 2.55
186 INT67621 Negative_regulation of Gene_expression of Ntrk2 7 0.41 2.71 2.52
187 INT13644 Negative_regulation of Phosphorylation of Th 2 0.43 0.06 2.51
188 INT101055 Regulation of GRIN2B 4 0.61 1.39 2.5
189 INT21313 Negative_regulation of Binding of Npy 5 0.42 0.39 2.49
190 INT95799 Binding of NTRK2 8 0.35 2.95 2.47
191 INT114026 Transcription of Grin1 7 0.67 3.13 2.45
192 INT163544 Binding of Psen1 40 0.36 15.28 2.42
193 INT61434 Regulation of Nf1 3 0.26 1.39 2.4
194 INT8666 Regulation of Regulation of Npy 3 0.21 0 2.4
195 INT15210 Negative_regulation of Transcription of Th 9 0.59 0.47 2.37
196 INT114024 Positive_regulation of Transcription of Grin1 1 0.49 1.69 2.37
197 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
198 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
199 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
200 INT64700 Binding of Nf1 14 0.45 15.24 2.29
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