GO:0021997

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Name neural plate axis specification
Categary Process
Go Slim No
Go Link GO:0021997
Unique Molecular Interactions 36
Total Molecular Interactions 53
Total Single Events 114
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neural plate axis specification. They are ordered first by their pain relevance and then by number of times they were reported for neural plate axis specification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139079 Tnip1 Negative_regulation of Ptch1 1 0.20 0.63 0.62
2 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
3 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
4 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
5 INT270457 Binding of Ptch1 and Gli1 1 0.02 1.3 0.08
6 INT255756 Ptch1 Positive_regulation of Phosphorylation of Pik3r1 1 0.16 1.08 0.03
7 INT255733 Ptch1 Positive_regulation of Pik3r1 1 0.16 1.08 0.03
8 INT255758 Ptch1 Positive_regulation of Akt1 1 0.21 1.14 0
9 INT255732 Ptch1 Positive_regulation of hs 1 0.06 1.26 0
10 INT205975 Binding of PTCH1 and Smo 1 0.02 0.72 0
11 INT255755 Ptch1 Regulation of Positive_regulation of Ins1 1 0.05 0.28 0
12 INT205958 GLI1 Positive_regulation of Gene_expression of PTCH1 1 0.35 0.57 0
13 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
14 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
15 INT255753 Ptch1 Positive_regulation of Phosphorylation of Gopc 1 0.13 1.33 0
16 INT260074 Binding of BRCA2 and PTCH1 1 0.40 0.15 0
17 INT256632 Binding of PTCH1 and Jkamp 1 0.00 2.32 0
18 INT255744 Binding of hs and Ptch1 1 0.06 1.32 0
19 INT205965 Binding of Ptch1 and Smo 1 0.03 0.72 0
20 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
21 INT255750 Ptch1 Positive_regulation of Ins1 1 0.10 0.35 0
22 INT260073 Binding of FANCC and PTCH1 1 0.33 0.49 0
23 INT260067 Binding of PTCH1 and XPA 1 0.26 1.08 0
24 INT205976 Binding of Ptch1 and SMOX 1 0.21 0.72 0
25 INT205962 Binding of PTCH1 and SMOX 1 0.14 0.72 0
26 INT255734 Ptch1 Regulation of Ins1 1 0.09 1.46 0
27 INT255760 Ptch1 Regulation of TNF 1 0.13 1.33 0
28 INT255741 Ptch1 Positive_regulation of Phosphorylation of Ins1 1 0.09 2.21 0
29 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
30 INT205961 GLI1 Positive_regulation of Negative_regulation of PTCH1 1 0.25 0.58 0
31 INT243232 Ighmbp2 Negative_regulation of Ptch1 1 0.02 0.22 0
32 INT255749 Ptch1 Positive_regulation of Phosphorylation of Slc2a4 1 0.15 1.32 0
33 INT255735 Ptch1 Positive_regulation of Phosphorylation of Akt1 1 0.27 2.83 0
34 INT255746 Hspa1a Positive_regulation of Positive_regulation of Ptch1 1 0.19 0.99 0
35 INT255739 Ptch1 Positive_regulation of Gene_expression of Hspa1a 1 0.18 0.75 0
36 INT255759 Ptch1 Positive_regulation of Phosphorylation of hs 1 0.06 1.34 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for neural plate axis specification. They are ordered first by their pain relevance and then by number of times they were reported in neural plate axis specification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113151 Positive_regulation of Ptch1 7 0.64 3.8 1.41
2 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29
3 INT135299 Binding of PTCH1 10 0.48 12.16 0.84
4 INT142416 Binding of Ptch1 6 0.34 4.92 0.74
5 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67
6 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56
7 INT183055 Gene_expression of PTCH1 10 0.77 15.54 0.26
8 INT260083 Regulation of PTCH1 11 0.27 4.46 0.09
9 INT270454 Regulation of Transcription of Ptch1 1 0.25 0.55 0.09
10 INT270450 Transcription of Ptch1 1 0.49 0.55 0.09
11 INT165148 Regulation of Binding of Ptch1 1 0.22 0.08 0.08
12 INT270452 Regulation of Gene_expression of Ptch1 1 0.25 0.25 0.08
13 INT165154 Negative_regulation of Positive_regulation of Ptch1 1 0.34 0.09 0.07
14 INT183056 Positive_regulation of Transcription of PTCH1 1 0.28 0.46 0.07
15 INT255719 Phosphorylation of Ptch1 1 0.32 3.7 0.06
16 INT255726 Localization of Ptch1 1 0.33 1.74 0.05
17 INT183070 Transcription of PTCH1 2 0.68 0.95 0.04
18 INT183064 Regulation of Gene_expression of PTCH1 1 0.34 0.22 0.03
19 INT205968 Negative_regulation of PTCH1 2 0.58 2.35 0
20 INT255723 Positive_regulation of Gene_expression of Ptch1 2 0.39 1.3 0
21 INT256631 Positive_regulation of PTCH1 2 0.13 1.97 0
22 INT260088 Negative_regulation of Transcription of PTCH1 1 0.43 0.4 0
23 INT260089 Localization of PTCH1 1 0.70 0.37 0
24 INT270455 Negative_regulation of Gene_expression of Ptch1 1 0.39 0.66 0
25 INT183052 Positive_regulation of Gene_expression of PTCH1 1 0.38 0.26 0
26 INT260080 Negative_regulation of Gene_expression of PTCH1 1 0.58 2.09 0
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