GO:0022038

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Name corpus callosum development
Categary Process
Go Slim No
Go Link GO:0022038
Unique Molecular Interactions 69
Total Molecular Interactions 84
Total Single Events 725
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for corpus callosum development. They are ordered first by their pain relevance and then by number of times they were reported for corpus callosum development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
2 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14
3 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
4 INT83804 Binding of EPHB3 and DRGX 1 0.00 0.62 0.62
5 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
6 INT108329 EGF Positive_regulation of Phosphorylation of EPHB2 4 0.48 3.96 0.48
7 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
8 INT278950 MAPK8 Negative_regulation of Localization of EPHB2 1 0.25 0.47 0.43
9 INT278964 MAPK14 Negative_regulation of Localization of EPHB2 1 0.15 0.47 0.43
10 INT71925 Binding of Ptprs and Positive_regulation of Racgap1 1 0.10 0 0.35
11 INT71924 Ptprs Positive_regulation of Racgap1 1 0.10 0 0.35
12 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
13 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
14 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
15 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
16 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 0.11 0.28 0.27
17 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
18 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
19 INT71923 Ptprs Regulation of Racgap1 1 0.09 0 0.21
20 INT326834 Cdk5r2 Positive_regulation of Cdk5 1 0.02 0.96 0.21
21 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19
22 INT222025 Gpx3 Regulation of EPHB2 1 0.01 1.41 0.18
23 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17
24 INT164791 Cdk5r1 Positive_regulation of Cdk5 1 0.30 0.25 0.17
25 INT222877 Chrm2 Negative_regulation of EPHB2 1 0.05 0.66 0.17
26 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16
27 INT273238 Grin1 Positive_regulation of Ptprs 1 0.07 0.51 0.14
28 INT287890 THEMIS Regulation of Gene_expression of EPHB2 1 0.00 0.87 0.14
29 INT287883 FOS Regulation of Gene_expression of EPHB2 1 0.01 0.87 0.14
30 INT273233 Negative_regulation of Cdk5 Negative_regulation of Positive_regulation of Ltp 1 0.20 0.39 0.13
31 INT326249 Prkcg Positive_regulation of EPHB2 1 0.06 0.63 0.13
32 INT326252 EPHB2 Positive_regulation of ras 1 0.03 0.62 0.13
33 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13
34 INT108330 EGF Negative_regulation of EPHB2 1 0.41 1.15 0.13
35 INT273239 Cdk5 Positive_regulation of Positive_regulation of GRIN1 1 0.51 0.37 0.12
36 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 0.36 0.38 0.1
37 INT273236 Cdk5 Positive_regulation of Car2 1 0.13 0.45 0.1
38 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1
39 INT224021 PIK3CG Negative_regulation of EPHB2 1 0.03 0.5 0.09
40 INT201751 Car2 Positive_regulation of Cdk5 1 0.00 0.67 0.09
41 INT224020 MAPK1 Negative_regulation of EPHB2 1 0.08 0.56 0.09
42 INT221954 Binding of CDK5 and CDK5R2 1 0.02 0.36 0.09
43 INT247948 Positive_regulation of Cdk5r1 Positive_regulation of Cdk5 1 0.26 0.16 0.07
44 INT218704 Mapk14 Regulation of EPHB2 1 0.01 0.33 0.05
45 INT218703 Mapk8 Regulation of EPHB2 1 0.04 0.33 0.05
46 INT216838 Binding of EPHB2 and Nfkb1 1 0.09 0.15 0.05
47 INT332329 Binding of Cdk5 and P2rx3 1 0.22 0.05 0.05
48 INT332331 Binding of Cdk5 and Rbm39 1 0.00 0.05 0.05
49 INT218705 Olr811 Regulation of EPHB2 1 0.01 0.32 0.05
50 INT326830 Cdk5r1 Positive_regulation of Positive_regulation of Cdk5 1 0.09 0.16 0.04
51 INT221639 Fyn Positive_regulation of Phosphorylation of Cdk5 1 0.14 0.28 0.03
52 INT221661 Sema3a Positive_regulation of Phosphorylation of Cdk5 1 0.19 0.28 0.03
53 INT218711 Olr811 Positive_regulation of Phosphorylation of EPHB2 1 0.02 0.33 0.03
54 INT332330 Cdk5 Negative_regulation of Pirt 1 0.00 0 0.03
55 INT333878 Shc1 Positive_regulation of EPHB2 1 0.08 0.3 0.03
56 INT219352 CDK5 Negative_regulation of PAK1 1 0.22 0.72 0.03
57 INT221613 Binding of Cdk5 and Fyn 1 0.10 0.29 0.03
58 INT221617 Fyn Positive_regulation of Cdk5 1 0.13 0.28 0.03
59 INT293801 EGF Positive_regulation of EPHB2 1 0.11 0 0
60 INT104029 RPGRIP1L Negative_regulation of Gene_expression of LTB 1 0.16 0.06 0
61 INT201734 Binding of Akt1 and Cdk5 1 0.01 0.31 0
62 INT201738 Positive_regulation of Binding of Akt1 and Cdk5 1 0.01 0.31 0
63 INT293819 EPHB2 Positive_regulation of AR 1 0.23 0.12 0
64 INT326197 Negative_regulation of HDAC9 Negative_regulation of EPHB2 1 0.17 0.15 0
65 INT201731 Negative_regulation of Binding of Akt1 and Cdk5 1 0.01 0.31 0
66 INT268446 Cdk5 Positive_regulation of Cdk5r1 1 0.02 0.58 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for corpus callosum development. They are ordered first by their pain relevance and then by number of times they were reported in corpus callosum development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
2 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
3 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
4 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
5 INT87650 Positive_regulation of EPHB2 49 0.67 22.77 8.25
6 INT108336 Phosphorylation of EPHB2 41 0.80 22.25 8.21
7 INT125143 Gene_expression of EPHB2 40 0.71 13.27 6.97
8 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
9 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
10 INT108342 Negative_regulation of EPHB2 18 0.57 9.48 4.46
11 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
12 INT15930 Positive_regulation of Ptprs 8 0.67 7.02 3.48
13 INT117836 Gene_expression of EPHB3 13 0.29 0.62 3.44
14 INT37601 Negative_regulation of Ptprs 8 0.42 3.7 3.29
15 INT108338 Positive_regulation of Phosphorylation of EPHB2 13 0.67 5.42 2.92
16 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
17 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
18 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
19 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
20 INT116077 Positive_regulation of Positive_regulation of EPHB2 4 0.67 2.32 2.13
21 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
22 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
23 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
24 INT224501 Positive_regulation of Gene_expression of EPHB2 9 0.49 4.29 1.39
25 INT109222 Positive_regulation of Negative_regulation of Cdk5 2 0.50 0.23 1.39
26 INT158709 Negative_regulation of Phosphorylation of Cdk5 1 0.40 0 1.39
27 INT109924 Localization of EPHB2 6 0.73 2.07 1.28
28 INT83805 Binding of EPHB3 1 0.00 1.15 1.19
29 INT108334 Negative_regulation of Phosphorylation of EPHB2 4 0.57 2.27 1.16
30 INT273221 Positive_regulation of Negative_regulation of Cdk5 8 0.49 9.89 1.03
31 INT142813 Localization of RPGRIP1L 1 0.59 0.99 1.01
32 INT125960 Gene_expression of Ptprs 8 0.78 2.87 0.99
33 INT203893 Positive_regulation of Gene_expression of Cdk5 2 0.49 7.12 0.92
34 INT138788 Positive_regulation of Gene_expression of Cdk5 1 0.49 0.44 0.91
35 INT127452 Positive_regulation of CDK5 5 0.32 1.88 0.87
36 INT203892 Positive_regulation of Positive_regulation of Cdk5 4 0.49 4.02 0.85
37 INT219358 Gene_expression of CDK5 9 0.58 5.65 0.81
38 INT138787 Positive_regulation of Positive_regulation of Cdk5 1 0.49 0.38 0.81
39 INT109912 Positive_regulation of Localization of EPHB2 2 0.49 0.56 0.77
40 INT196790 Localization of Cdk5 6 0.74 2.6 0.67
41 INT209225 Regulation of Ptprs 3 0.12 1.84 0.63
42 INT127557 Positive_regulation of Phosphorylation of Cdk5 2 0.50 0.43 0.56
43 INT278982 Regulation of EPHB2 6 0.44 1.97 0.53
44 INT125139 Regulation of Gene_expression of EPHB2 3 0.44 1.07 0.52
45 INT224498 Regulation of Positive_regulation of EPHB2 1 0.26 0.46 0.52
46 INT120403 Regulation of Phosphorylation of EPHB2 2 0.60 1.92 0.5
47 INT71922 Binding of Ptprs 2 0.11 0.29 0.37
48 INT273218 Negative_regulation of Negative_regulation of Cdk5 1 0.42 3.06 0.37
49 INT221973 Negative_regulation of CDK5 4 0.57 2.26 0.36
50 INT278976 Negative_regulation of Gene_expression of EPHB2 1 0.41 0.51 0.32
51 INT131265 Positive_regulation of Gene_expression of EPHB3 2 0.19 0 0.28
52 INT326820 Negative_regulation of Positive_regulation of Cdk5 1 0.36 1.27 0.28
53 INT298972 Transcription of Cdk5 1 0.15 1.63 0.28
54 INT109932 Protein_catabolism of EPHB2 3 0.86 0.14 0.24
55 INT109923 Positive_regulation of Protein_catabolism of EPHB2 1 0.49 0.14 0.24
56 INT164788 Regulation of Gene_expression of Cdk5 1 0.27 0.31 0.24
57 INT209220 Regulation of Regulation of Ptprs 1 0.09 0.56 0.23
58 INT219375 Localization of CDK5 4 0.52 2.8 0.19
59 INT221974 Phosphorylation of CDK5 1 0.56 0.99 0.19
60 INT273226 Negative_regulation of Gene_expression of Cdk5 2 0.42 0.79 0.17
61 INT157582 Regulation of Phosphorylation of Cdk5 1 0.26 0.25 0.16
62 INT221972 Regulation of CDK5 1 0.42 1.87 0.16
63 INT326822 Negative_regulation of Phosphorylation of Cdk5 1 0.36 0.43 0.12
64 INT341559 Positive_regulation of Gene_expression of CDK5 1 0.23 0.25 0.11
65 INT201655 Negative_regulation of Binding of Cdk5 1 0.06 0.9 0.09
66 INT341567 Negative_regulation of Gene_expression of CDK5 1 0.27 0.24 0.07
67 INT219355 Binding of CDK5 3 0.35 2.02 0.06
68 INT235653 Binding of EPHB2 1 0.08 1.04 0
69 INT326230 Regulation of Negative_regulation of EPHB2 1 0.44 0 0
70 INT268444 Regulation of Positive_regulation of Cdk5 1 0.08 0.66 0
71 INT326234 Regulation of Protein_catabolism of EPHB2 1 0.44 0 0
72 INT326236 Negative_regulation of Negative_regulation of EPHB2 1 0.41 0 0
73 INT266536 Negative_regulation of Protein_catabolism of EPHB2 1 0.41 0 0
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