GO:0022417

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Name protein maturation by protein folding
Categary Process
Go Slim No
Go Link GO:0022417
Unique Molecular Interactions 48
Total Molecular Interactions 66
Total Single Events 338
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein maturation by protein folding. They are ordered first by their pain relevance and then by number of times they were reported for protein maturation by protein folding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
2 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64
3 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
4 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37
5 INT39594 TPO Positive_regulation of CALR 1 0.30 0.91 0.32
6 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24
7 INT318980 Binding of CALR and Positive_regulation of Localization of GOPC 1 0.04 0.32 0.24
8 INT354114 Binding of CALR and SST 1 0.01 0.1 0.16
9 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12
10 INT167040 Binding of Aip and Drb1 1 0.10 0.54 0.1
11 INT167041 Binding of HLA-A and Aip 1 0.02 0.54 0.1
12 INT145987 Binding of CTLA4 and Aip 1 0.08 0.61 0.09
13 INT308432 Binding of PDE4A and Aip 1 0.05 3.1 0.05
14 INT293360 Binding of CSH1 and FKBP1A 1 0.00 0.14 0.05
15 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03
16 INT308425 Binding of Pde2a and Aip 1 0.04 1.37 0
17 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
18 INT336994 CALR Negative_regulation of ESR1 1 0.04 0 0
19 INT351732 SSD Regulation of CALR 1 0.01 2.95 0
20 INT307306 Gene_expression of COMP Positive_regulation of CALR 1 0.27 0.99 0
21 INT307305 Gene_expression of COMP Positive_regulation of Positive_regulation of CALR 1 0.27 0.41 0
22 INT333928 Binding of CALR and ESR1 1 0.09 0.09 0
23 INT351733 CALR Positive_regulation of ROS1 1 0.03 0.3 0
24 INT161823 Positive_regulation of Binding of Igha and Aip 1 0.01 0.16 0
25 INT351730 CALR Positive_regulation of Positive_regulation of ROS1 1 0.02 0.72 0
26 INT265233 Binding of APC and FKBP1A 1 0.08 0.41 0
27 INT161822 Binding of Igha and Aip 1 0.00 0.16 0
28 INT265234 Binding of FKBP1A and SGCG 1 0.03 0.35 0
29 INT265232 Regulation of Binding of APC and FKBP1A 1 0.08 0.41 0
30 INT333931 Binding of CALR and PDIA3 1 0.18 0.18 0
31 INT307309 Binding of CALR and EREG 1 0.00 0.83 0
32 INT161825 Binding of IgG and Aip 1 0.01 0.32 0
33 INT351095 Binding of FKBP1A and RPS6KB1 1 0.24 0.36 0
34 INT351101 Negative_regulation of Binding of FKBP1A and RPS6KB1 1 0.27 0.36 0
35 INT279131 LTF Positive_regulation of CALR 1 0.03 2.39 0
36 INT307310 Binding of CALR and COMP 1 0.28 0.82 0
37 INT308426 Binding of Pde4a and Aip 1 0.02 0.89 0
38 INT161824 Positive_regulation of Binding of and Aip 1 0.01 0.32 0
39 INT351096 Binding of FKBP1A and MTOR 1 0.28 1.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein maturation by protein folding. They are ordered first by their pain relevance and then by number of times they were reported in protein maturation by protein folding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121801 Binding of Aip 18 0.36 24.1 5.26
2 INT112989 Gene_expression of AIP 3 0.56 25.4 4.23
3 INT148671 Gene_expression of Aip 26 0.63 24.32 3.91
4 INT120062 Binding of AIP 4 0.42 28.86 3.91
5 INT3564 Positive_regulation of Aip 11 0.58 15.38 3.62
6 INT54555 Negative_regulation of CALR 10 0.41 4.41 2.4
7 INT70526 Binding of CALR 11 0.35 7.09 1.97
8 INT21941 Regulation of CALR 7 0.53 3.88 1.96
9 INT287798 Localization of AIP 1 0.63 5.96 1.31
10 INT114091 Negative_regulation of Aip 6 0.48 4.16 1.3
11 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25
12 INT287799 Positive_regulation of Gene_expression of AIP 1 0.42 7.39 1.19
13 INT274238 Positive_regulation of AIP 2 0.42 8.14 0.97
14 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95
15 INT230251 Binding of FKBP1A 6 0.28 2.24 0.94
16 INT162801 Localization of CALR 7 0.73 8.69 0.6
17 INT154613 Regulation of Aip 5 0.21 3.86 0.55
18 INT154449 Positive_regulation of Gene_expression of Aip 2 0.43 2.88 0.52
19 INT144179 Localization of Aip 4 0.61 2.59 0.33
20 INT287800 Positive_regulation of Positive_regulation of AIP 1 0.42 2.15 0.3
21 INT195871 Positive_regulation of Gene_expression of CALR 9 0.29 3 0.27
22 INT356135 Positive_regulation of Binding of Aip 1 0.09 0.81 0.24
23 INT318982 Positive_regulation of Binding of CALR 1 0.09 0.32 0.24
24 INT356136 Negative_regulation of Localization of Aip 1 0.08 0.88 0.23
25 INT164519 Gene_expression of FKBP1A 2 0.39 0.22 0.19
26 INT167038 Binding of Aip 2 0.21 2.13 0.19
27 INT287797 Phosphorylation of AIP 1 0.78 2.04 0.16
28 INT293345 Negative_regulation of Binding of FKBP1A 1 0.02 0.19 0.13
29 INT112990 Negative_regulation of AIP 1 0.10 0.59 0.09
30 INT299319 Localization of FKBP1A 1 0.44 0 0.09
31 INT167037 Regulation of Aip 1 0.25 0.71 0.09
32 INT354146 Regulation of Gene_expression of CALR 1 0.04 0.73 0.07
33 INT299313 Positive_regulation of Gene_expression of FKBP1A 1 0.29 0 0.05
34 INT308415 Negative_regulation of Transcription of Aip 1 0.48 0.82 0.03
35 INT308414 Negative_regulation of Gene_expression of Aip 1 0.48 0.82 0.03
36 INT353546 Positive_regulation of Localization of CALR 1 0.05 0.49 0.03
37 INT307326 Negative_regulation of Gene_expression of CALR 3 0.25 1.78 0
38 INT307324 Positive_regulation of Positive_regulation of CALR 1 0.25 0.36 0
39 INT308416 Regulation of Gene_expression of Aip 1 0.37 0.77 0
40 INT307331 Negative_regulation of Positive_regulation of CALR 1 0.29 0.36 0
41 INT308417 Transcription of Aip 1 0.59 0.82 0
42 INT307332 Negative_regulation of Localization of CALR 1 0.29 0.72 0
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