GO:0022839

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Name ion gated channel activity
Categary Function
Go Slim No
Go Link GO:0022839
Unique Molecular Interactions 33
Total Molecular Interactions 40
Total Single Events 532
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ion gated channel activity. They are ordered first by their pain relevance and then by number of times they were reported for ion gated channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140004 Srxn1 Negative_regulation of Accn2 1 0.01 0.47 0.83
2 INT98525 Binding of Accn2 and Accn3 1 0.01 0.38 0.68
3 INT152282 Binding of Accn1 and Trpv1 1 0.10 0.42 0.49
4 INT354218 Igfbp7 Positive_regulation of Accn1 1 0.04 0.74 0.44
5 INT354206 Arc Positive_regulation of Accn2 1 0.02 0.57 0.42
6 INT354221 Igfbp7 Positive_regulation of Accn2 1 0.11 0.57 0.42
7 INT140802 Accn2 Regulation of Transcription of Accn1 1 0.24 0 0.36
8 INT208037 Binding of Accn1 and Accn3 1 0.15 0.3 0.25
9 INT208036 Binding of Cnga3 and Accn1 1 0.01 0.3 0.25
10 INT330797 Positive_regulation of Accn2 Positive_regulation of Ca2 1 0.03 0 0.23
11 INT354217 Arc Positive_regulation of Accn1 1 0.01 0.29 0.21
12 INT354211 Igfbp7 Positive_regulation of Gene_expression of Accn1 1 0.04 0.29 0.2
13 INT354216 Binding of Accn3 and Positive_regulation of Gene_expression of Accn1 1 0.06 0.29 0.2
14 INT354225 Accn3 Positive_regulation of Gene_expression of Accn1 1 0.06 0.29 0.2
15 INT354214 Arc Positive_regulation of Gene_expression of Accn1 1 0.01 0.29 0.2
16 INT330795 Positive_regulation of Accn2 Positive_regulation of Positive_regulation of Ca2 1 0.03 0 0.18
17 INT330798 Fig4 Negative_regulation of Gene_expression of Accn2 1 0.03 0 0.16
18 INT208051 Binding of SNRNP70 and Accn1 1 0.01 1.81 0
19 INT354699 Binding of Accn2 and Pick1 1 0.07 0.22 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ion gated channel activity. They are ordered first by their pain relevance and then by number of times they were reported in ion gated channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98521 Gene_expression of Accn2 52 0.74 23.45 35.09
2 INT98524 Positive_regulation of Accn2 15 0.49 9.48 11.57
3 INT68290 Gene_expression of Accn1 32 0.73 7.36 11.23
4 INT93191 Gene_expression of Accn2 22 0.76 10.04 8.91
5 INT120651 Positive_regulation of Gene_expression of Accn2 13 0.66 9.02 8.58
6 INT126989 Transcription of Accn2 8 0.63 5.22 6.77
7 INT93193 Positive_regulation of Accn2 16 0.69 7.2 6.37
8 INT93195 Negative_regulation of Accn2 14 0.59 7.23 6.31
9 INT93192 Transcription of Accn2 5 0.52 4.63 4.79
10 INT81086 Positive_regulation of Accn1 8 0.65 7.51 4.62
11 INT147028 Negative_regulation of Accn2 6 0.14 2.06 3.92
12 INT72253 Positive_regulation of Accn1 8 0.63 2.64 2.73
13 INT142310 Negative_regulation of Gene_expression of Accn2 3 0.30 2.07 2.64
14 INT295924 Regulation of Gene_expression of Accn2 5 0.14 2.82 2.62
15 INT75551 Localization of Accn1 6 0.68 1.75 2.58
16 INT72254 Gene_expression of Accn1 9 0.71 3.24 2.46
17 INT136190 Transcription of Accn1 5 0.61 2.75 2.24
18 INT98523 Localization of Accn2 4 0.22 1.07 2.16
19 INT166766 Regulation of Accn2 2 0.11 2.02 2.16
20 INT135892 Localization of Accn2 4 0.74 2.23 2.12
21 INT99951 Regulation of Accn1 5 0.26 2.65 2.1
22 INT104899 Regulation of Accn2 5 0.39 3.47 2.07
23 INT165083 Positive_regulation of Positive_regulation of Accn1 1 0.47 3.91 2.07
24 INT147030 Positive_regulation of Positive_regulation of Accn2 3 0.21 1.44 1.94
25 INT165081 Positive_regulation of Positive_regulation of Accn2 3 0.49 2.79 1.9
26 INT136192 Negative_regulation of Gene_expression of Accn2 1 0.35 2.44 1.71
27 INT295922 Positive_regulation of Transcription of Accn2 1 0.14 2.19 1.45
28 INT159464 Negative_regulation of Accn1 4 0.37 1.07 1.41
29 INT165082 Regulation of Gene_expression of Accn2 1 0.27 1.64 1.4
30 INT72250 Binding of Accn1 3 0.44 2.87 1.27
31 INT91914 Binding of Accn1 3 0.36 0.44 1.24
32 INT131136 Binding of Accn2 3 0.36 1.44 1.23
33 INT112703 Binding of Accn2 4 0.37 0.64 1.19
34 INT93194 Negative_regulation of Transcription of Accn2 2 0.35 1.69 1
35 INT136193 Positive_regulation of Gene_expression of Accn2 1 0.38 1.43 0.97
36 INT68289 Positive_regulation of Gene_expression of Accn1 2 0.45 0.34 0.83
37 INT143673 Regulation of Gene_expression of Accn1 4 0.43 0.81 0.78
38 INT242575 Positive_regulation of Transcription of Accn2 1 0.18 0.15 0.64
39 INT208024 Negative_regulation of Binding of Accn1 1 0.39 1.26 0.5
40 INT166767 Negative_regulation of Gene_expression of Accn1 1 0.12 0.13 0.44
41 INT140798 Localization of Accn1 3 0.76 0.24 0.34
42 INT119656 Regulation of Accn1 1 0.31 0.2 0.33
43 INT140800 Negative_regulation of Gene_expression of Accn1 1 0.40 0.08 0.33
44 INT285182 Negative_regulation of Accn1 1 0.04 1.06 0.31
45 INT91915 Negative_regulation of Binding of Accn1 1 0.19 0 0.25
46 INT147753 Negative_regulation of Negative_regulation of Accn2 1 0.43 0.53 0.24
47 INT147752 Regulation of Negative_regulation of Accn2 1 0.27 0.44 0.22
48 INT208021 Positive_regulation of Gene_expression of Accn1 1 0.63 0.21 0.07
49 INT79048 Positive_regulation of Localization of Accn1 2 0.46 0.45 0.05
50 INT208022 Regulation of Gene_expression of Accn1 1 0.41 0.13 0
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