GO:0022891

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Name substrate-specific transmembrane transporter activity
Categary Function
Go Slim No
Go Link GO:0022891
Unique Molecular Interactions 30
Total Molecular Interactions 33
Total Single Events 436
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for substrate-specific transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported for substrate-specific transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94241 Binding of Cp and Slc2a2 1 0.13 0.81 0.67
2 INT141871 Binding of Nos3 and Slc2a4 1 0.25 0.51 0.28
3 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
4 INT120975 Ins1 Positive_regulation of Gene_expression of Slc2a4 1 0.19 0.75 0.27
5 INT55300 Slc2a1 Regulation of Gene_expression of Slc2a4 1 0.41 0.41 0.19
6 INT55295 Slc2a1 Regulation of Ins1 1 0.17 0.41 0.19
7 INT55296 Slc2a4 Regulation of Ins1 1 0.17 0.41 0.19
8 INT55299 Slc2a4 Regulation of Gene_expression of Slc2a1 1 0.41 0.41 0.19
9 INT126922 Ins1 Positive_regulation of Localization of Slc2a4 1 0.23 0.75 0.11
10 INT229333 Binding of Nr1h2 and Positive_regulation of Gene_expression of SLC2A4 1 0.02 0.62 0.07
11 INT55297 Gene_expression of Slc2a4 Positive_regulation of Ins1 1 0.19 0.36 0.06
12 INT238314 Pik3cb Negative_regulation of Localization of Slc2a4 1 0.06 0.25 0.05
13 INT267046 Binding of SLC2A1 and SV2A 1 0.12 0 0.05
14 INT329219 Ins1 Positive_regulation of Gene_expression of Slc2a4 1 0.04 0.93 0.05
15 INT352519 INS Positive_regulation of Localization of Slc2a4 1 0.07 0.97 0.03
16 INT323483 Slc2a2 Positive_regulation of Localization of Ins1 1 0.07 0.1 0.03
17 INT348220 Glp1r Regulation of Slc2a1 1 0.12 0.66 0.03
18 INT348225 Glp1r Regulation of Localization of Slc2a4 1 0.36 0.66 0.03
19 INT348226 Glp1r Regulation of Localization of Slc2a1 1 0.26 1.03 0.03
20 INT348223 Glp1r Regulation of Positive_regulation of Slc2a4 1 0.26 0.66 0.03
21 INT348224 Glp1r Regulation of Slc2a4 1 0.26 0.66 0.03
22 INT255752 hs Positive_regulation of Phosphorylation of Slc2a4 1 0.08 1.32 0
23 INT144754 Negative_regulation of Binding of Insr and Slc2a2 1 0.01 0 0
24 INT296959 NRIP1 Regulation of SLC2A4 1 0.22 0.54 0
25 INT284098 HNF1A Positive_regulation of SLC2A1 1 0.36 1.16 0
26 INT337734 ADAMTS2 Positive_regulation of Gene_expression of SLC2A2 1 0.01 0 0
27 INT144753 Binding of Insr and Slc2a2 1 0.01 0 0
28 INT255749 Ptch1 Positive_regulation of Phosphorylation of Slc2a4 1 0.15 1.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for substrate-specific transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported in substrate-specific transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48131 Gene_expression of Slc2a4 32 0.78 14.64 10.16
2 INT99430 Positive_regulation of Gene_expression of Slc2a4 18 0.66 10.45 7.79
3 INT115250 Positive_regulation of Slc2a4 16 0.67 8.13 2.64
4 INT48130 Transcription of Slc2a4 9 0.69 5.58 2.46
5 INT55291 Gene_expression of Slc2a1 20 0.68 11.46 2.16
6 INT14010 Gene_expression of SLC2A1 19 0.78 15.22 2.12
7 INT94239 Negative_regulation of Slc2a2 4 0.43 2.34 1.94
8 INT115256 Localization of Slc2a4 13 0.77 8.06 1.72
9 INT115309 Gene_expression of Slc2a1 6 0.75 2.85 1.64
10 INT48126 Negative_regulation of Gene_expression of Slc2a4 5 0.59 1.79 1.63
11 INT48128 Regulation of Gene_expression of Slc2a4 5 0.62 1.25 1.59
12 INT230805 Localization of Slc2a4 23 0.46 11 1.48
13 INT48129 Negative_regulation of Slc2a4 7 0.59 3.19 1.21
14 INT55294 Gene_expression of Slc2a4 17 0.70 6.84 1.11
15 INT154437 Positive_regulation of Slc2a1 4 0.26 2.67 1.08
16 INT94237 Positive_regulation of Slc2a2 3 0.50 0.65 0.97
17 INT141865 Positive_regulation of Transcription of Slc2a4 3 0.45 2.78 0.87
18 INT115249 Binding of Slc2a4 7 0.36 2.63 0.8
19 INT112780 Positive_regulation of Slc2a1 6 0.46 1.85 0.78
20 INT230808 Positive_regulation of Localization of Slc2a4 12 0.40 5.42 0.7
21 INT13654 Regulation of SLC2A1 1 0.44 0.44 0.68
22 INT94234 Binding of Slc2a2 2 0.37 0.78 0.65
23 INT48133 Regulation of Slc2a4 2 0.45 0.23 0.6
24 INT7630 Negative_regulation of SLC2A1 4 0.45 0.73 0.56
25 INT215899 Negative_regulation of Gene_expression of Slc2a1 6 0.43 3.96 0.55
26 INT94236 Regulation of Slc2a2 1 0.39 0.6 0.53
27 INT55293 Positive_regulation of Gene_expression of Slc2a4 7 0.63 4.18 0.51
28 INT48132 Negative_regulation of Transcription of Slc2a4 1 0.43 0 0.48
29 INT55292 Positive_regulation of Gene_expression of Slc2a1 5 0.61 2.98 0.46
30 INT231553 Localization of Slc2a1 2 0.48 3.96 0.39
31 INT126919 Regulation of Localization of Slc2a4 3 0.40 2.24 0.37
32 INT253118 Negative_regulation of Localization of Slc2a4 3 0.25 2.47 0.33
33 INT260463 Regulation of Slc2a1 2 0.27 1.58 0.33
34 INT347246 Positive_regulation of Gene_expression of SLC2A1 1 0.21 0.28 0.32
35 INT347245 Regulation of Gene_expression of SLC2A1 1 0.14 0.28 0.32
36 INT126920 Phosphorylation of Slc2a4 3 0.73 1.98 0.31
37 INT184526 Phosphorylation of Slc2a1 2 0.18 1.53 0.29
38 INT62808 Positive_regulation of SLC2A4 7 0.50 3.3 0.24
39 INT62810 Localization of SLC2A4 5 0.81 0.77 0.22
40 INT136401 Binding of SLC2A1 2 0.36 1.75 0.22
41 INT126921 Positive_regulation of Phosphorylation of Slc2a4 2 0.41 1.26 0.21
42 INT229317 Gene_expression of SLC2A4 10 0.69 6.88 0.2
43 INT231256 Regulation of Slc2a4 3 0.21 0.76 0.18
44 INT290795 Gene_expression of Slc2a2 3 0.44 1.22 0.16
45 INT277389 Positive_regulation of Gene_expression of SLC2A4 4 0.61 2.87 0.14
46 INT62809 Positive_regulation of Localization of SLC2A4 3 0.70 0.8 0.14
47 INT337742 Gene_expression of SLC2A2 2 0.38 1.72 0.14
48 INT308623 Localization of Slc2a2 1 0.23 0.1 0.14
49 INT339747 Negative_regulation of Gene_expression of SLC2A2 1 0.21 0.73 0.14
50 INT115251 Positive_regulation of Localization of Slc2a4 2 0.66 0.9 0.11
51 INT229102 Regulation of Phosphorylation of Slc2a4 1 0.00 0.53 0.11
52 INT236581 Regulation of Gene_expression of Slc2a4 3 0.36 0.5 0.09
53 INT348219 Regulation of Localization of Slc2a1 1 0.27 0.61 0.08
54 INT352512 Regulation of Localization of Slc2a4 1 0.06 0.66 0.08
55 INT158977 Transcription of SLC2A1 6 0.53 3.44 0.06
56 INT158982 Positive_regulation of Transcription of SLC2A1 3 0.45 1.66 0.06
57 INT258085 Regulation of Localization of SLC2A4 1 0.22 0.75 0.06
58 INT238308 Negative_regulation of Localization of Slc2a4 1 0.12 0.25 0.05
59 INT253095 Regulation of Gene_expression of Slc2a1 1 0.30 0.14 0.04
60 INT250742 Negative_regulation of SLC2A2 2 0.09 0.86 0.03
61 INT215896 Binding of Slc2a1 2 0.36 0.42 0.03
62 INT250741 Negative_regulation of Negative_regulation of SLC2A2 1 0.07 0.92 0.03
63 INT253101 Binding of Slc2a4 1 0.21 0 0.03
64 INT348202 Positive_regulation of Localization of Slc2a1 1 0.30 0.65 0.03
65 INT296982 Positive_regulation of SLC2A1 3 0.53 1.95 0
66 INT144750 Gene_expression of Slc2a2 2 0.20 0.86 0
67 INT348212 Regulation of Gene_expression of Slc2a1 1 0.16 0.65 0
68 INT348208 Negative_regulation of Gene_expression of Slc2a1 1 0.26 0.32 0
69 INT296979 Regulation of Gene_expression of SLC2A4 1 0.19 0.56 0
70 INT296970 Positive_regulation of Transcription of SLC2A4 1 0.32 0.99 0
71 INT268312 Negative_regulation of Negative_regulation of Slc2a4 1 0.26 0.31 0
72 INT348201 Negative_regulation of Binding of Slc2a1 1 0.25 0.5 0
73 INT317361 Negative_regulation of Gene_expression of Slc2a4 1 0.40 0.15 0
74 INT277382 Negative_regulation of SLC2A4 1 0.38 0.48 0
75 INT144749 Regulation of Binding of Slc2a2 1 0.03 0 0
76 INT158981 Regulation of Transcription of SLC2A1 1 0.20 0 0
77 INT296971 Binding of SLC2A4 1 0.26 1.13 0
78 INT348209 Negative_regulation of Slc2a1 1 0.25 0.49 0
79 INT290825 Negative_regulation of Gene_expression of SLC2A1 1 0.29 0.32 0
80 INT336105 Positive_regulation of Slc2a4 1 0.39 0.63 0
81 INT339776 Positive_regulation of Gene_expression of SLC2A2 1 0.24 0.99 0
82 INT144748 Negative_regulation of Negative_regulation of Slc2a2 1 0.05 0 0
83 INT144751 Negative_regulation of Gene_expression of Slc2a2 1 0.05 0 0
84 INT215898 Regulation of Slc2a1 1 0.20 0.47 0
85 INT144752 Positive_regulation of Negative_regulation of Slc2a2 1 0.06 0 0
86 INT348216 Binding of Slc2a1 1 0.22 0.5 0
87 INT268302 Negative_regulation of Slc2a4 1 0.26 0.31 0
88 INT296961 Positive_regulation of Binding of SLC2A4 1 0.35 1.14 0
89 INT267062 Negative_regulation of Binding of SLC2A1 1 0.14 0 0
90 INT348210 Negative_regulation of Binding of Slc2a4 1 0.25 0.5 0
91 INT311771 Negative_regulation of Positive_regulation of SLC2A1 1 0.33 0.17 0
92 INT296983 Transcription of SLC2A4 1 0.37 1.56 0
93 INT255722 Phosphorylation of Slc2a4 1 0.46 1.3 0
94 INT315103 Localization of SLC2A1 1 0.51 0.26 0
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