GO:0023021

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Name termination of signal transduction
Categary Process
Go Slim No
Go Link GO:0023021
Unique Molecular Interactions 11
Total Molecular Interactions 11
Total Single Events 175
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for termination of signal transduction. They are ordered first by their pain relevance and then by number of times they were reported for termination of signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
2 INT120384 PRKCD Positive_regulation of Localization of HSPG2 1 0.29 0.42 0.51
3 INT120382 PRKCD Positive_regulation of Localization of DYT10 1 0.29 0.42 0.51
4 INT8356 Binding of YY1 and Smpd1 1 0.32 0 0.43
5 INT210935 Il6 Positive_regulation of Smpd1 1 0.02 0.46 0.3
6 INT149940 Smpd1 Positive_regulation of spc 1 0.03 0.19 0.24
7 INT173358 Gnaq Positive_regulation of SMPD1 1 0.01 0.13 0.23
8 INT302982 Smpd1 Positive_regulation of Gene_expression of Smpd3 1 0.30 0.64 0.04
9 INT345350 Casp3 Positive_regulation of Prkcd 1 0.05 0.79 0.03
10 INT333637 Smpd1 Positive_regulation of IRF3 1 0.09 0.62 0
11 INT230713 Binding of Prkcd and Gsk3b 1 0.34 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for termination of signal transduction. They are ordered first by their pain relevance and then by number of times they were reported in termination of signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT171033 Localization of SMPD1 15 0.16 11.92 5.16
2 INT171019 Gene_expression of SMPD1 26 0.27 12.08 5.08
3 INT84430 Negative_regulation of Smpd1 22 0.59 10.33 3.95
4 INT171013 Regulation of SMPD1 4 0.11 4.84 2.74
5 INT171032 Positive_regulation of SMPD1 9 0.12 8.94 2.52
6 INT86914 Positive_regulation of Smpd1 11 0.43 4.73 1.74
7 INT20233 Negative_regulation of SMPD1 8 0.51 4.19 1.4
8 INT163914 Positive_regulation of Prkcd 1 0.67 1.43 1.12
9 INT171038 Positive_regulation of Localization of SMPD1 2 0.08 1.8 0.99
10 INT120393 Negative_regulation of PRKCD 3 0.22 1.07 0.86
11 INT120396 Positive_regulation of Localization of PRKCD 1 0.26 0.42 0.85
12 INT112760 Negative_regulation of Positive_regulation of Smpd1 2 0.38 1.45 0.84
13 INT120392 Localization of PRKCD 1 0.39 0.4 0.83
14 INT171030 Positive_regulation of Gene_expression of SMPD1 2 0.09 0.92 0.82
15 INT171024 Negative_regulation of Localization of SMPD1 1 0.07 1.29 0.72
16 INT171043 Negative_regulation of Gene_expression of SMPD1 2 0.08 1.15 0.53
17 INT120390 Phosphorylation of PRKCD 1 0.33 0.38 0.49
18 INT120394 Positive_regulation of PRKCD 2 0.26 1.58 0.41
19 INT120391 Negative_regulation of Localization of PRKCD 1 0.22 0 0.34
20 INT120398 Positive_regulation of Positive_regulation of PRKCD 1 0.26 0 0.33
21 INT173329 Protein_catabolism of SMPD1 1 0.13 0 0.31
22 INT84638 Regulation of Smpd1 3 0.37 2.36 0.22
23 INT138438 Gene_expression of Smpd1 7 0.67 2.67 0.21
24 INT309940 Localization of Smpd1 3 0.21 2.79 0.21
25 INT138436 Positive_regulation of Gene_expression of Smpd1 3 0.41 0.6 0.17
26 INT171035 Binding of SMPD1 1 0.06 1.57 0.17
27 INT147970 Positive_regulation of Positive_regulation of Smpd1 3 0.43 0.88 0.15
28 INT173347 Regulation of Gene_expression of SMPD1 1 0.07 0.48 0.14
29 INT209698 Gene_expression of PRKCD 1 0.33 1.78 0.12
30 INT147971 Positive_regulation of Negative_regulation of Smpd1 1 0.43 0 0.11
31 INT63795 Phosphorylation of Smpd1 1 0.00 0 0.11
32 INT20232 Negative_regulation of Negative_regulation of SMPD1 1 0.37 0.55 0.1
33 INT209688 Negative_regulation of Positive_regulation of PRKCD 1 0.18 1.1 0.08
34 INT302963 Protein_catabolism of Smpd1 1 0.39 0.86 0.08
35 INT267192 Localization of Prkcd 1 0.78 0.96 0.03
36 INT267186 Positive_regulation of Localization of Prkcd 1 0.49 0.97 0.03
37 INT230666 Regulation of Binding of Prkcd 1 0.44 0 0
38 INT320839 Regulation of Gene_expression of Smpd1 1 0.37 0.61 0
39 INT230673 Binding of Prkcd 1 0.36 0 0
40 INT209686 Negative_regulation of Gene_expression of PRKCD 1 0.18 0 0
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