GO:0030016

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Name myofibril
Categary Component
Go Slim No
Go Link GO:0030016
Unique Molecular Interactions 51
Total Molecular Interactions 58
Total Single Events 1079
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for myofibril. They are ordered first by their pain relevance and then by number of times they were reported for myofibril. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149925 Negative_regulation of Cpox Negative_regulation of Gene_expression of Pde4d 1 0.01 0.39 0.84
2 INT89875 Pdyn Positive_regulation of Localization of Myh6 1 0.09 0 0.66
3 INT155898 Binding of KCNJ8 and MMD 1 0.09 0.39 0.53
4 INT273350 Pde7a Positive_regulation of Localization of Pde4d 1 0.33 1.35 0.49
5 INT297229 Binding of Kcnj8 and Abcc8 1 0.03 0 0.42
6 INT214412 CASQ1 Regulation of JUND 1 0.02 0.46 0.24
7 INT151424 Tfrc Negative_regulation of Positive_regulation of Tnni3 1 0.21 0.98 0.2
8 INT130740 Regulation of Binding of Tnnt2 and Mb 1 0.00 0.47 0.19
9 INT130741 Binding of Tnnt2 and Mb 1 0.01 0.47 0.19
10 INT301782 Binding of Dmd and Utrn 1 0.24 0.15 0.18
11 INT301784 Binding of Dmd and Sntb1 1 0.05 0.36 0.16
12 INT219597 Prkaca Positive_regulation of Pde4d 1 0.29 0 0.15
13 INT219599 Pde4d Regulation of Prkaca 1 0.28 0 0.12
14 INT301788 Binding of Dmd and Dtna 1 0.09 0.05 0.12
15 INT243996 Binding of Dag1 and Dmd 1 0.04 0.08 0.11
16 INT168856 Binding of Tnnt2 and Fabp3 1 0.05 0.57 0.09
17 INT219600 Pde4d Regulation of Binding of Prkaca 1 0.28 0 0.09
18 INT219602 Binding of Prkaca and Pde4d 1 0.23 0 0.09
19 INT146007 Gene_expression of TRPV1 Positive_regulation of Gene_expression of MYH2 1 0.11 0.06 0.06
20 INT273353 Pde4d Regulation of Gene_expression of Twist1 1 0.26 0.25 0.05
21 INT301786 Negative_regulation of Binding of Dmd and Sntb1 1 0.06 0.31 0.04
22 INT271025 Binding of Car2 and Casq1 1 0.03 0.7 0.03
23 INT327052 Gene_expression of Akt1 Positive_regulation of Gene_expression of Myod1 1 0.19 0.18 0
24 INT283862 Binding of CALD1 and MYH14 1 0.02 0 0
25 INT322245 Binding of Hcm and Myh7 1 0.11 1.28 0
26 INT219596 Binding of Pde4a and Pde4d 1 0.28 0.31 0
27 INT258202 ROCK1 Positive_regulation of MYL2 1 0.14 0.2 0
28 INT322244 Binding of Hcm and Mybpc3 1 0.11 0.85 0
29 INT321772 Binding of Myo7a and Twf2 1 0.00 0 0
30 INT322259 Binding of Hcm and Tpm1 1 0.10 0.85 0
31 INT231167 Cphx Positive_regulation of Gene_expression of Dmd 1 0.02 0.17 0
32 INT340554 Myod1 Positive_regulation of Negative_regulation of Mapk1 1 0.28 0.25 0
33 INT322249 Binding of Hcm and Tnnt2 1 0.11 0.86 0
34 INT340551 Myod1 Positive_regulation of Mapk1 1 0.19 0.25 0
35 INT356377 Dmd Positive_regulation of Negative_regulation of Mib2 1 0.03 0.51 0
36 INT299628 MSTN Negative_regulation of Gene_expression of MYOD1 1 0.09 0.15 0
37 INT231168 Binding of Dmd and Nos1 1 0.11 0.06 0
38 INT231169 Gnas Positive_regulation of Gene_expression of Dmd 1 0.00 0.19 0
39 INT295576 Binding of Dmd and Mstn 1 0.23 1.1 0
40 INT340559 Myod1 Positive_regulation of Myog 1 0.12 0.25 0
41 INT296929 Gene_expression of Casq1 Positive_regulation of Tmie 1 0.00 0.43 0
42 INT272197 Binding of CAPN3 and DYSF 1 0.42 0.38 0
43 INT296930 Casq1 Negative_regulation of RYR1 1 0.00 0.38 0
44 INT277310 Binding of Tnnt2 and Mbnl1 1 0.18 1.1 0
45 INT322257 Binding of Mybpc3 and Myh7 1 0.34 0.43 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for myofibril. They are ordered first by their pain relevance and then by number of times they were reported in myofibril. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16923 Positive_regulation of Tnni3 32 0.50 25.01 5.44
2 INT63957 Positive_regulation of Tnnt2 33 0.69 18.56 5.41
3 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34
4 INT105775 Gene_expression of Pde4d 31 0.78 4.18 5.21
5 INT221226 Gene_expression of Kcnj8 23 0.58 1.69 4.84
6 INT79399 Gene_expression of Pde4d 6 0.70 2.83 2.51
7 INT107489 Negative_regulation of Pde4d 3 0.42 0 2.47
8 INT168097 Transcription of Tnnt2 1 0.07 2.12 2.47
9 INT89146 Localization of Tnni3 7 0.51 4.31 2.38
10 INT81247 Gene_expression of Tnnt2 9 0.31 2.06 2.37
11 INT51869 Negative_regulation of Dmd 24 0.52 10.4 2.18
12 INT107490 Positive_regulation of Pde4d 3 0.69 0.07 2.13
13 INT105824 Regulation of Casq1 4 0.07 2.66 2.1
14 INT118896 Regulation of Tnnt2 4 0.44 2.94 2.09
15 INT105776 Negative_regulation of Gene_expression of Pde4d 5 0.59 2.2 2.01
16 INT63959 Regulation of Tnni3 11 0.21 4.69 1.57
17 INT72458 Positive_regulation of Tnnt2 5 0.69 5.59 1.38
18 INT47434 Gene_expression of Tnnt2 14 0.60 10.4 1.37
19 INT135924 Positive_regulation of Gene_expression of Pde4d 2 0.59 0 1.28
20 INT65324 Gene_expression of Tnni3 12 0.66 7.97 1.25
21 INT149924 Negative_regulation of Gene_expression of Pde4d 1 0.26 0.81 1.24
22 INT216103 Positive_regulation of Dmd 15 0.46 5.92 1.21
23 INT240799 Localization of Kcnj8 2 0.07 0.82 1.19
24 INT96117 Negative_regulation of Tnnt2 3 0.13 1.61 1.1
25 INT163159 Gene_expression of Casq1 2 0.58 1.21 1.09
26 INT231162 Localization of Dmd 6 0.71 2.27 1.07
27 INT219589 Binding of Pde4d 13 0.47 0.51 1.01
28 INT219568 Positive_regulation of Pde4d 9 0.49 1.74 1
29 INT167329 Transcription of Kcnj8 4 0.06 0.87 0.9
30 INT116314 Gene_expression of Myod1 38 0.70 16.6 0.89
31 INT161775 Negative_regulation of Localization of Tnni3 1 0.23 0.85 0.86
32 INT219578 Negative_regulation of Pde4d 3 0.46 2.95 0.8
33 INT135923 Regulation of Gene_expression of Pde4d 2 0.44 0 0.8
34 INT118753 Regulation of Negative_regulation of Pde4d 1 0.02 0 0.8
35 INT130496 Positive_regulation of Kcnj8 2 0.10 0.63 0.78
36 INT68650 Negative_regulation of Tnni3 8 0.37 1.01 0.73
37 INT63958 Regulation of Tnnt2 7 0.45 5.36 0.7
38 INT272206 Gene_expression of CAPN3 4 0.77 3.83 0.7
39 INT83343 Negative_regulation of Kcnj8 4 0.37 1 0.7
40 INT216104 Positive_regulation of Gene_expression of Dmd 23 0.46 4.52 0.68
41 INT89870 Localization of Myh6 1 0.26 0 0.65
42 INT219580 Localization of Pde4d 5 0.73 2.07 0.64
43 INT64536 Binding of Tnnt2 4 0.32 2.47 0.64
44 INT200164 Binding of Dmd 5 0.42 2.35 0.56
45 INT287853 Phosphorylation of Tnni3 1 0.63 0.87 0.56
46 INT79397 Positive_regulation of Gene_expression of Pde4d 1 0.45 0.2 0.55
47 INT146784 Gene_expression of MYOD1 13 0.74 4.41 0.54
48 INT155905 Localization of KCNJ8 1 0.73 0.49 0.51
49 INT219573 Positive_regulation of Localization of Pde4d 2 0.49 1.39 0.5
50 INT167328 Regulation of Kcnj8 1 0.04 0.47 0.49
51 INT155907 Transcription of KCNJ8 1 0.69 0.48 0.48
52 INT102692 Localization of MYH2 1 0.26 0.45 0.47
53 INT216108 Negative_regulation of Gene_expression of Dmd 12 0.45 1.32 0.46
54 INT65323 Positive_regulation of Positive_regulation of Tnni3 5 0.36 1.93 0.46
55 INT239951 Regulation of Positive_regulation of Dmd 1 0.41 0.39 0.43
56 INT88005 Binding of MYOD1 6 0.30 2.08 0.42
57 INT297227 Binding of Kcnj8 1 0.03 0 0.42
58 INT216105 Regulation of Gene_expression of Dmd 7 0.36 2.55 0.41
59 INT219565 Regulation of Pde4d 3 0.44 0.5 0.39
60 INT64537 Localization of Tnnt2 5 0.76 1.57 0.37
61 INT73898 Positive_regulation of Regulation of Tnnt2 1 0.44 0.83 0.37
62 INT273330 Positive_regulation of Negative_regulation of Pde4d 1 0.39 1.25 0.35
63 INT342958 Positive_regulation of Gene_expression of CAPN3 1 0.69 0.66 0.35
64 INT158967 Positive_regulation of Gene_expression of Tnni3 2 0.49 1.31 0.34
65 INT301730 Regulation of Negative_regulation of Dmd 1 0.40 0.28 0.3
66 INT81901 Binding of Tnni3 2 0.07 0.62 0.27
67 INT280603 Transcription of Myod1 4 0.67 1.22 0.24
68 INT230957 Positive_regulation of CALD1 3 0.45 1.88 0.24
69 INT273341 Transcription of Pde4d 2 0.54 0.68 0.24
70 INT185719 Regulation of Gene_expression of MYOD1 1 0.07 0 0.24
71 INT273336 Regulation of Negative_regulation of Pde4d 1 0.35 0.68 0.24
72 INT213438 Gene_expression of CALD1 2 0.31 0.39 0.21
73 INT272484 Negative_regulation of Myod1 8 0.39 6.77 0.2
74 INT117571 Gene_expression of Myh7 5 0.27 1.43 0.2
75 INT272202 Negative_regulation of CAPN3 4 0.59 0.99 0.2
76 INT231152 Regulation of Dmd 9 0.47 3.64 0.19
77 INT85574 Negative_regulation of Negative_regulation of Tnni3 1 0.29 0.1 0.19
78 INT342960 Regulation of CAPN3 1 0.45 0.39 0.18
79 INT342959 Protein_catabolism of CAPN3 1 0.87 0.41 0.16
80 INT155908 Negative_regulation of KCNJ8 1 0.42 0.18 0.16
81 INT297228 Regulation of Gene_expression of Kcnj8 1 0.04 0.12 0.15
82 INT272949 Positive_regulation of Myod1 6 0.36 5.31 0.14
83 INT301740 Positive_regulation of Localization of Dmd 1 0.44 0.15 0.14
84 INT311452 Gene_expression of CASQ1 1 0.74 7.58 0.14
85 INT297218 Positive_regulation of Gene_expression of Kcnj8 1 0.05 0.06 0.14
86 INT219593 Regulation of Binding of Pde4d 1 0.44 0 0.13
87 INT316918 Negative_regulation of Localization of Dmd 1 0.42 0.7 0.13
88 INT316919 Localization of Dmd 1 0.78 0.7 0.13
89 INT239954 Negative_regulation of Localization of Dmd 1 0.34 0.06 0.12
90 INT219214 Positive_regulation of Gene_expression of MYOD1 1 0.35 0.21 0.12
91 INT287862 Phosphorylation of Tnnt2 1 0.42 0.07 0.12
92 INT287860 Regulation of Phosphorylation of Tnni3 1 0.21 0.16 0.12
93 INT301739 Transcription of Dmd 1 0.61 0 0.12
94 INT287850 Positive_regulation of Phosphorylation of Tnni3 1 0.54 0.09 0.11
95 INT243993 Binding of Dmd 1 0.35 0.08 0.11
96 INT166811 Regulation of Casq1 3 0.04 1.18 0.1
97 INT311275 Regulation of Gene_expression of Tnnt2 2 0.34 1.33 0.1
98 INT121284 Positive_regulation of Gene_expression of Tnnt2 2 0.46 0.89 0.1
99 INT219574 Phosphorylation of Pde4d 1 0.79 0.33 0.1
100 INT193893 Gene_expression of Tpm1 5 0.65 1.65 0.09
101 INT121285 Regulation of Positive_regulation of Tnnt2 2 0.45 0.84 0.09
102 INT166810 Gene_expression of Casq1 2 0.10 2.16 0.08
103 INT168853 Binding of Tnnt2 2 0.19 0.4 0.08
104 INT272945 Protein_catabolism of Myod1 1 0.35 2.1 0.08
105 INT166809 Binding of Casq1 1 0.05 0.34 0.08
106 INT272469 Negative_regulation of Gene_expression of Myod1 5 0.39 2.82 0.07
107 INT146008 Gene_expression of MYH2 2 0.32 0.16 0.06
108 INT327713 Negative_regulation of Casq1 1 0.02 0.11 0.06
109 INT342956 Positive_regulation of Negative_regulation of CAPN3 1 0.46 0.16 0.06
110 INT146010 Positive_regulation of Gene_expression of MYH2 1 0.15 0.06 0.06
111 INT219585 Positive_regulation of Positive_regulation of Pde4d 1 0.43 0 0.06
112 INT226169 Positive_regulation of Gene_expression of Tpm1 2 0.49 1.17 0.05
113 INT322228 Gene_expression of Mybpc3 1 0.62 0.44 0.05
114 INT104302 Localization of Tnnt2 2 0.70 0.52 0.04
115 INT301741 Phosphorylation of Dmd 1 0.72 0.45 0.04
116 INT340173 Positive_regulation of Transcription of Myod1 1 0.14 0.26 0.04
117 INT183436 Positive_regulation of Localization of Tnnt2 1 0.30 0.45 0.04
118 INT311456 Positive_regulation of Gene_expression of CASQ1 1 0.66 0.79 0.03
119 INT316920 Negative_regulation of Dmd 1 0.42 0.33 0.03
120 INT271021 Binding of Casq1 1 0.03 0.64 0.03
121 INT204938 Positive_regulation of Casq1 1 0.08 0.17 0.03
122 INT272946 Localization of Myod1 3 0.56 1.6 0
123 INT301729 Positive_regulation of Gene_expression of Myod1 2 0.24 1.53 0
124 INT183067 Gene_expression of MYL2 2 0.25 1.19 0
125 INT231153 Positive_regulation of Positive_regulation of Dmd 2 0.29 1.43 0
126 INT281600 Positive_regulation of Casq1 2 0.05 0.66 0
127 INT239989 Gene_expression of Myh6 2 0.55 0 0
128 INT255134 Positive_regulation of Localization of Tnnt2 1 0.44 0.15 0
129 INT248265 Regulation of Pde4d 1 0.21 0.87 0
130 INT299630 Negative_regulation of Gene_expression of MYOD1 1 0.16 0.15 0
131 INT311453 Binding of CASQ1 1 0.31 0.44 0
132 INT272203 Binding of CAPN3 1 0.37 0.23 0
133 INT227665 Transcription of MYOD1 1 0.23 0.3 0
134 INT283886 Positive_regulation of Positive_regulation of CALD1 1 0.18 0 0
135 INT296911 Positive_regulation of Gene_expression of Casq1 1 0.09 1.49 0
136 INT301744 Regulation of Phosphorylation of Dmd 1 0.40 0.14 0
137 INT342957 Positive_regulation of CAPN3 1 0.43 0.18 0
138 INT239953 Regulation of Binding of Dmd 1 0.41 0 0
139 INT311445 Positive_regulation of CASQ1 1 0.39 0.7 0
140 INT239982 Positive_regulation of Positive_regulation of Myh6 1 0.46 0 0
141 INT287846 Positive_regulation of Phosphorylation of Tnnt2 1 0.25 0 0
142 INT296922 Negative_regulation of Casq1 1 0.06 0.38 0
143 INT296909 Regulation of Transcription of Casq1 1 0.08 1.15 0
144 INT193842 Negative_regulation of Tpm1 1 0.09 0 0
145 INT296927 Localization of Casq1 1 0.10 0.32 0
146 INT283883 Positive_regulation of Gene_expression of CALD1 1 0.28 0 0
147 INT287835 Negative_regulation of Phosphorylation of Tnni3 1 0.33 0 0
148 INT239981 Positive_regulation of Myh6 1 0.46 0 0
149 INT283897 Positive_regulation of Phosphorylation of CALD1 1 0.32 0.32 0
150 INT283890 Phosphorylation of CALD1 1 0.37 1.95 0
151 INT239986 Regulation of Myh6 1 0.25 0 0
152 INT342954 Positive_regulation of Positive_regulation of CAPN3 1 0.43 0.1 0
153 INT321731 Positive_regulation of Gene_expression of Twf2 1 0.15 0 0
154 INT296916 Negative_regulation of Gene_expression of Casq1 1 0.06 0.44 0
155 INT219570 Negative_regulation of Positive_regulation of Pde4d 1 0.42 0 0
156 INT321750 Localization of Twf2 1 0.17 0 0
157 INT342961 Negative_regulation of Gene_expression of CAPN3 1 0.43 0.1 0
158 INT255106 Positive_regulation of Binding of Tnnt2 1 0.44 0.17 0
159 INT321740 Gene_expression of Twf2 1 0.17 0 0
160 INT272948 Negative_regulation of Localization of Myod1 1 0.15 1.43 0
161 INT219575 Positive_regulation of Binding of Pde4d 1 0.49 0 0
162 INT204718 Localization of MYOD1 1 0.29 0 0
163 INT311454 Regulation of CASQ1 1 0.43 0.07 0
164 INT239961 Regulation of Localization of Dmd 1 0.41 0.16 0
165 INT272944 Positive_regulation of Localization of Myod1 1 0.17 1.44 0
166 INT272950 Regulation of Gene_expression of Myod1 1 0.41 0.7 0
167 INT231159 Negative_regulation of Positive_regulation of Dmd 1 0.16 0 0
168 INT287863 Binding of MYL2 1 0.05 0 0
169 INT248559 Positive_regulation of Tpm1 1 0.13 0.07 0
170 INT321754 Binding of Twf2 1 0.08 0 0
171 INT231148 Protein_catabolism of Dmd 1 0.32 0.5 0
172 INT296926 Transcription of Casq1 1 0.10 1.85 0
173 INT231160 Positive_regulation of Protein_catabolism of Dmd 1 0.15 0.51 0
174 INT340534 Regulation of Myod1 1 0.14 0.61 0
175 INT272939 Positive_regulation of Negative_regulation of Myod1 1 0.16 0.78 0
176 INT321746 Regulation of Gene_expression of Twf2 1 0.10 0 0
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