GO:0030018

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Name Z disc
Categary Component
Go Slim No
Go Link GO:0030018
Unique Molecular Interactions 441
Total Molecular Interactions 579
Total Single Events 6192
Pain Genes Associated 59

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for Z disc. They are ordered first by their pain relevance and then by number of times they were reported for Z disc. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
2 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
3 INT297489 Ryr2 Regulation of Positive_regulation of Ltp 1 0.05 0.16 1.64
4 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
5 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
6 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
7 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
8 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
9 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
10 INT158545 Binding of Trpc3 and Jph2 1 0.55 0 1.24
11 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
12 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
13 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
14 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
15 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
16 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
17 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
18 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
19 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
20 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
21 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
22 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
23 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
24 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
25 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
26 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
27 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
28 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
29 INT63488 Sptan1 Positive_regulation of Rtcd1 1 0.03 0.34 0.91
30 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
31 INT52759 Oprd1 Regulation of Sptan1 1 0.03 0 0.9
32 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9
33 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89
34 INT305406 Binding of CAV3 and ST8SIA2 1 0.16 0 0.86
35 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
36 INT152949 Homer1 Regulation of Sgk1 1 0.28 0.18 0.76
37 INT152946 Homer1 Regulation of Cap1 1 0.32 0.18 0.76
38 INT107028 KNG1 Regulation of Des 1 0.01 1.7 0.76
39 INT152948 Homer1 Regulation of Gpr88 1 0.36 0.18 0.75
40 INT296285 Binding of Car1 and Grin2b 1 0.14 0.32 0.72
41 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
42 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
43 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
44 INT296298 Grin2b Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
45 INT104110 Negative_regulation of Adrbk2 Negative_regulation of Oprm1 1 0.00 0 0.71
46 INT123077 Cacna1c Negative_regulation of Gene_expression of Dbi 1 0.05 0.71 0.7
47 INT104102 Negative_regulation of Adrbk2 Negative_regulation of Oprl1 1 0.06 0 0.7
48 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69
49 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
50 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
51 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
52 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
53 INT89875 Pdyn Positive_regulation of Localization of Myh6 1 0.09 0 0.66
54 INT72146 POMC Positive_regulation of Phosphorylation of MYOT 1 0.00 0.25 0.65
55 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63
56 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
57 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
58 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
59 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
60 INT120348 Negative_regulation of Binding of DES and MYC 1 0.06 0.18 0.58
61 INT120349 Binding of BDKRB1 and DES 1 0.05 0.17 0.58
62 INT120350 Binding of DES and MYC 1 0.05 0.17 0.58
63 INT253835 Binding of DST and Fos 1 0.02 0 0.55
64 INT251141 Binding of Dlg4 and Grin2b 1 0.14 0.32 0.55
65 INT251143 Binding of Grin2b and Dlg3 1 0.22 0.32 0.55
66 INT350169 Binding of DMD and MRI1 1 0.11 3.08 0.54
67 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
68 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
69 INT297479 Ryr2 Positive_regulation of Ca2 1 0.22 0 0.52
70 INT208121 Binding of Grin2a and Grin2b 3 0.35 0.06 0.51
71 INT250080 Grin2b Positive_regulation of Ltp 1 0.22 0.19 0.49
72 INT208119 Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.16 0.21 0.49
73 INT81064 Negative_regulation of Nts Negative_regulation of Gene_expression of Homer1 1 0.01 0 0.48
74 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
75 INT349853 Binding of Hspb1 and Jun 1 0.14 2.3 0.45
76 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
77 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42
78 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42
79 INT244421 Binding of DST and Ctss 1 0.02 0.42 0.41
80 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
81 INT67633 Binding of DST and Gabrd 1 0.03 0 0.41
82 INT62555 CPN1 Positive_regulation of DES 1 0.10 0.37 0.41
83 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 0.22 0.09 0.41
84 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4
85 INT296296 Binding of Grin2b and Kcnip3 1 0.24 0 0.4
86 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4
87 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39
88 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
89 INT150196 Grm5 Regulation of Grin2b 1 0.45 0 0.36
90 INT331966 Binding of DES and SACM1L 1 0.01 1.86 0.36
91 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 0.01 0.23 0.35
92 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
93 INT352547 Binding of CFTR and DMD 1 0.01 1.42 0.35
94 INT25526 Dst Regulation of Gh 1 0.00 0.26 0.34
95 INT236006 HTR1A Regulation of Grin2b 1 0.00 0 0.33
96 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
97 INT138469 Cpb2 Negative_regulation of Gene_expression of Ryr2 1 0.04 0.25 0.32
98 INT263749 Binding of Grin2b and Neto1 1 0.38 0 0.3
99 INT244422 Binding of DST and Fig4 1 0.01 0.42 0.29
100 INT250079 Grin2b Regulation of Ltp 1 0.18 0.31 0.29
101 INT83568 Adrbk2 Regulation of Oprk1 1 0.02 0 0.29
102 INT180570 Binding of HEYL and Positive_regulation of DMD 1 0.00 1.08 0.28
103 INT70096 Csrp3 Positive_regulation of Mpo 1 0.10 0.19 0.28
104 INT180564 HEYL Regulation of Regulation of DMD 1 0.00 0.88 0.28
105 INT291641 Binding of DST and ESRRG 1 0.16 1.8 0.28
106 INT44091 Binding of ACTN1 and CAMSAP2 1 0.08 0 0.28
107 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
108 INT257577 CALCA Positive_regulation of DMD 1 0.01 0.57 0.26
109 INT345008 Binding of ACTN1 and CSF2 1 0.02 0.53 0.26
110 INT120191 Ccl4 Positive_regulation of Pdlim3 1 0.51 0.24 0.25
111 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
112 INT150582 Creb1 Positive_regulation of Gene_expression of Homer1 1 0.00 0 0.22
113 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
114 INT208123 Hpcal1 Regulation of Grin2b 1 0.10 0 0.21
115 INT174679 Homer1 Regulation of Luc7l3 1 0.02 0.67 0.21
116 INT354519 Cacna1c Regulation of Mri1 1 0.00 1.15 0.21
117 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2
118 INT250074 Grin2b Positive_regulation of Gene_expression of Hpcal4 1 0.04 0.3 0.2
119 INT291642 Binding of DST and GGT1 1 0.00 1.4 0.19
120 INT301083 Binding of BCS1L and MYH7 1 0.36 1.53 0.19
121 INT349855 Atf3 Regulation of Hspb1 1 0.37 0.77 0.19
122 INT66279 Binding of FLNB and HLA-B 1 0.41 0.57 0.19
123 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
124 INT301782 Binding of Dmd and Utrn 1 0.24 0.15 0.18
125 INT347446 CD99 Positive_regulation of Binding of DES 1 0.46 1.01 0.17
126 INT274353 DST Regulation of Gopc 1 0.00 0 0.17
127 INT301784 Binding of Dmd and Sntb1 1 0.05 0.36 0.16
128 INT186954 Binding of Des and Nsdhl 1 0.06 0.32 0.16
129 INT58179 Gtf3a Positive_regulation of Gene_expression of Homer1 1 0.07 0.1 0.16
130 INT298448 Binding of SLC4A1 and Slc4a3 1 0.39 1.89 0.15
131 INT180566 Binding of COMP and DMD 1 0.02 0.72 0.15
132 INT347638 Negative_regulation of Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
133 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14
134 INT94763 PSEN2 Regulation of Positive_regulation of App 1 0.11 0.72 0.14
135 INT347639 Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
136 INT173942 Binding of DMD and Atp6v1e1 1 0.00 0 0.13
137 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
138 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
139 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
140 INT86429 Binding of Hspb1 and Esr1 1 0.19 0.26 0.13
141 INT224125 Adrbk2 Positive_regulation of Phosphorylation of Adora3 1 0.04 0 0.13
142 INT265982 Homer1 Regulation of Grm5 1 0.04 0.38 0.12
143 INT301788 Binding of Dmd and Dtna 1 0.09 0.05 0.12
144 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
145 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
146 INT249495 Binding of Grin2b and Efnb2 1 0.02 0.05 0.11
147 INT243996 Binding of Dag1 and Dmd 1 0.04 0.08 0.11
148 INT263729 Grin2b Positive_regulation of Gene_expression of Car1 1 0.20 0 0.1
149 INT214012 Binding of Ank1 and Nav1 1 0.01 0.51 0.1
150 INT214011 Negative_regulation of Binding of Ank1 and Nav1 1 0.01 0.51 0.1
151 INT101880 Oxt Positive_regulation of Gene_expression of Homer1 1 0.23 0.14 0.1
152 INT72848 RT1-EC2 Positive_regulation of Adrbk2 1 0.00 0.33 0.1
153 INT72847 Adrbk2 Positive_regulation of Adrbk1 1 0.02 0.33 0.1
154 INT349340 SRI Regulation of Rpe 1 0.02 0.05 0.09
155 INT202392 Binding of Osm and Nexn 1 0.02 0.13 0.09
156 INT137394 Binding of DES and CD99 1 0.17 1.04 0.09
157 INT147673 SRI Positive_regulation of Per1 1 0.03 0 0.09
158 INT214168 Msx1 Positive_regulation of Gene_expression of DST 1 0.00 0.13 0.09
159 INT214166 DST Negative_regulation of Gene_expression of Npy 1 0.02 0.07 0.09
160 INT265981 Homer1 Regulation of Localization of Grm5 1 0.04 0.06 0.09
161 INT20959 Binding of PTPRC and Pak1 1 0.01 0.76 0.09
162 INT350106 Binding of SLC4A3 and SLC4A1 1 0.13 2.78 0.09
163 INT202393 Binding of Mapk14 and Nexn 1 0.03 0.13 0.09
164 INT270777 Binding of DMD and BPs 1 0.01 0.33 0.09
165 INT232917 Binding of KRT8 and KRT19 2 0.16 1.04 0.08
166 INT147661 Binding of GRP and SRI 1 0.00 0 0.08
167 INT311083 DST Regulation of FOS 1 0.03 0.15 0.08
168 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
169 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
170 INT20957 Binding of Pak1 and Pak2 1 0.27 0.65 0.08
171 INT221477 Gadd45b Negative_regulation of SRI 1 0.03 0.27 0.08
172 INT68008 Binding of DES and Hba-a1 1 0.03 1.3 0.08
173 INT137256 BCL2L11 Regulation of SLC4A1 1 0.24 0.99 0.08
174 INT201173 Sox2 Positive_regulation of Localization of Ryr2 1 0.40 0.9 0.07
175 INT159852 Gene_expression of IL2 Regulation of Gene_expression of ACTN1 1 0.03 0.16 0.07
176 INT263755 Grin1 Regulation of Localization of Grin2b 1 0.27 0.17 0.07
177 INT339111 Binding of ERBB2 and JUP 1 0.38 0.62 0.07
178 INT279767 Binding of IGHG3 and KRT19 1 0.01 0.84 0.07
179 INT263741 Grin2b Regulation of Localization of Dlg4 1 0.17 0.17 0.07
180 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
181 INT356379 DMD Positive_regulation of Negative_regulation of Utrn 1 0.54 0.84 0.07
182 INT263728 Grin2b Regulation of Localization of Grin1 1 0.27 0.17 0.07
183 INT263723 Grin2b Regulation of Localization of Gria2 1 0.18 0.17 0.07
184 INT265983 Homer1 Regulation of Ryr1 1 0.37 0.15 0.07
185 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
186 INT263762 Grin2a Regulation of Localization of Grin2b 1 0.26 0.17 0.07
187 INT263722 Dlg4 Regulation of Localization of Grin2b 1 0.15 0.17 0.07
188 INT263739 Grin2b Regulation of Localization of Vamp2 1 0.24 0.17 0.07
189 INT111933 Cacna1c Positive_regulation of PENK 1 0.01 0 0.07
190 INT263768 Grin2b Regulation of Localization of Grin2a 1 0.26 0.17 0.07
191 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
192 INT263767 Binding of Camk2a and Grin2b 1 0.18 0 0.06
193 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
194 INT341680 Binding of DES and Vim 1 0.02 0.59 0.06
195 INT267214 Hspb8 Negative_regulation of Cryab 1 0.32 1.56 0.06
196 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06
197 INT135641 Binding of Dst and Ina 1 0.35 0.34 0.06
198 INT254463 Binding of Camk2a and Cacna1c 1 0.00 0.17 0.06
199 INT231300 Positive_regulation of Grin2b Positive_regulation of Prnp 1 0.39 0.16 0.05
200 INT263763 Localization of Neto1 Regulation of Localization of Grin2b 1 0.36 0.18 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for Z disc. They are ordered first by their pain relevance and then by number of times they were reported in Z disc. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
2 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
3 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
4 INT7898 Gene_expression of Homer1 123 0.78 31.52 53.67
5 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
6 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
7 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
8 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
9 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
10 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
11 INT7899 Positive_regulation of Gene_expression of Homer1 41 0.70 7.29 25.98
12 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
13 INT47818 Positive_regulation of Homer1 48 0.70 11.11 24.05
14 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
15 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
16 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
17 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
18 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25
19 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06
20 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
21 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
22 INT47702 Gene_expression of Sptan1 24 0.76 7.6 11.36
23 INT25963 Gene_expression of DES 122 0.75 98.81 11.25
24 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
25 INT60995 Negative_regulation of Positive_regulation of Homer1 9 0.38 1.63 9.63
26 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
27 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
28 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
29 INT15242 Regulation of Gene_expression of Homer1 14 0.62 4.33 9.28
30 INT168096 Transcription of Cav3 1 0.72 7.23 8.58
31 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
32 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
33 INT7813 Regulation of SRI 25 0.61 6.18 8.13
34 INT73181 Gene_expression of Hspb1 24 0.78 15.84 7.31
35 INT71496 Positive_regulation of Hspb1 15 0.69 14.7 6.86
36 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
37 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
38 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
39 INT54713 Gene_expression of Adrbk2 12 0.65 0.08 5.92
40 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
41 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
42 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78
43 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45
44 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34
45 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
46 INT130478 Localization of Grin2b 11 0.75 2.49 5.28
47 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
48 INT53974 Regulation of Homer1 14 0.39 4.71 4.9
49 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
50 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25
51 INT112100 Negative_regulation of Gene_expression of Grin2b 6 0.42 3.71 4.24
52 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
53 INT3127 Gene_expression of SRI 38 0.68 26.29 3.82
54 INT52755 Positive_regulation of Sptan1 6 0.67 1.57 3.82
55 INT163500 Transcription of Grin2b 3 0.67 3.63 3.8
56 INT9798 Negative_regulation of Gene_expression of Homer1 10 0.41 2.04 3.77
57 INT139646 Positive_regulation of Positive_regulation of Grin2b 4 0.42 3.89 3.74
58 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
59 INT16165 Regulation of DMD 114 0.60 35.13 3.64
60 INT137702 Binding of TTN 7 0.35 4.48 3.62
61 INT18282 Binding of SRI 10 0.36 3.31 3.59
62 INT102076 Regulation of DST 15 0.22 10 3.5
63 INT60714 Regulation of Positive_regulation of Homer1 3 0.04 0.64 3.46
64 INT171998 Binding of DMD 58 0.47 38.13 3.35
65 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29
66 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
67 INT52756 Negative_regulation of Sptan1 7 0.42 1.31 3.19
68 INT137549 Gene_expression of Pygm 12 0.05 6.74 3.16
69 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
70 INT201152 Regulation of Ryr2 5 0.32 2.8 2.99
71 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
72 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
73 INT48219 Gene_expression of SLC4A1 34 0.75 33.18 2.84
74 INT58173 Negative_regulation of Homer1 5 0.43 1 2.79
75 INT24068 Localization of Hspb1 6 0.78 6.11 2.75
76 INT82278 Positive_regulation of Positive_regulation of Homer1 5 0.13 2.32 2.73
77 INT158157 Phosphorylation of Csrp3 1 0.03 1.28 2.68
78 INT144057 Transcription of SRI 5 0.67 7.94 2.6
79 INT65603 Positive_regulation of SRI 8 0.41 2.32 2.56
80 INT101055 Regulation of GRIN2B 4 0.61 1.39 2.5
81 INT37621 Gene_expression of Des 6 0.65 2.17 2.48
82 INT144274 Gene_expression of Cav3 28 0.78 3.21 2.47
83 INT54435 Binding of Sptan1 8 0.36 4.7 2.44
84 INT163544 Binding of Psen1 40 0.36 15.28 2.42
85 INT59784 Binding of DES 22 0.47 19.48 2.27
86 INT34596 Binding of Des 5 0.36 3.26 2.27
87 INT86426 Gene_expression of Hspb1 16 0.78 10.86 2.26
88 INT19286 Negative_regulation of Cacna1c 11 0.46 5.12 2.22
89 INT168959 Gene_expression of CAV3 5 0.65 0.7 2.2
90 INT51869 Negative_regulation of Dmd 24 0.52 10.4 2.18
91 INT65119 Negative_regulation of Des 4 0.41 1.29 2.14
92 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
93 INT54433 Transcription of Sptan1 1 0.69 0 2.03
94 INT60723 Localization of Psen2 5 0.68 2.11 2.02
95 INT246518 Regulation of Negative_regulation of Grin2b 1 0.38 0.07 1.99
96 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
97 INT112368 Positive_regulation of Cacna1c 8 0.46 2.94 1.97
98 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
99 INT151942 Regulation of Negative_regulation of Grin2b 2 0.41 0.41 1.92
100 INT61845 Transcription of Homer1 9 0.72 2.28 1.85
101 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82
102 INT23956 Negative_regulation of DES 12 0.42 10.84 1.82
103 INT74594 Regulation of Transcription of Grin2b 1 0.42 0.17 1.8
104 INT277591 Gene_expression of Hdac4 22 0.77 7.77 1.79
105 INT130440 Phosphorylation of GRIN2B 2 0.79 2.93 1.79
106 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
107 INT52758 Negative_regulation of Positive_regulation of Sptan1 2 0.57 0.33 1.73
108 INT168964 Negative_regulation of Gene_expression of CAV3 1 0.47 0 1.68
109 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
110 INT63520 Localization of Homer1 4 0.75 0.38 1.63
111 INT52188 Positive_regulation of Des 2 0.16 1.56 1.63
112 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
113 INT83563 Positive_regulation of Gene_expression of Adrbk2 2 0.58 0 1.57
114 INT54711 Regulation of Adrbk2 1 0.59 0 1.57
115 INT123076 Gene_expression of Cacna1c 7 0.37 1.91 1.56
116 INT135640 Negative_regulation of Dst 5 0.57 2.25 1.56
117 INT62127 Localization of SRI 12 0.45 10.21 1.54
118 INT104106 Localization of Adrbk2 3 0.19 0.35 1.53
119 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
120 INT107379 Localization of GRIN2B 2 0.73 0.86 1.48
121 INT15048 Regulation of Cacna1c 4 0.29 3.26 1.47
122 INT7812 Negative_regulation of SRI 10 0.59 4.28 1.46
123 INT65452 Negative_regulation of Cacna1c 8 0.09 0.8 1.44
124 INT78646 Regulation of Psen2 4 0.20 1.78 1.42
125 INT296265 Regulation of Phosphorylation of Grin2b 2 0.44 1.06 1.4
126 INT82279 Regulation of Negative_regulation of Homer1 1 0.02 0 1.36
127 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
128 INT129179 Gene_expression of Ank1 4 0.31 0.47 1.35
129 INT54712 Positive_regulation of Adrbk2 3 0.66 0.34 1.35
130 INT37203 Negative_regulation of Pygm 3 0.06 1.64 1.33
131 INT77752 Binding of Cacna1c 3 0.22 0.22 1.31
132 INT24069 Negative_regulation of Localization of Hspb1 3 0.14 3.93 1.3
133 INT38645 Negative_regulation of Positive_regulation of DST 3 0.29 1.05 1.29
134 INT104636 Regulation of TTN 2 0.33 0 1.29
135 INT277581 Positive_regulation of Hdac4 4 0.50 1.47 1.25
136 INT113858 Positive_regulation of SLC4A1 6 0.49 3.44 1.22
137 INT249527 Positive_regulation of Positive_regulation of Grin2b 2 0.37 1.12 1.22
138 INT216103 Positive_regulation of Dmd 15 0.46 5.92 1.21
139 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
140 INT104777 Regulation of DES 4 0.38 2.38 1.2
141 INT137548 Positive_regulation of Pygm 2 0.04 2.26 1.2
142 INT168095 Positive_regulation of Transcription of Cav3 1 0.47 0.91 1.2
143 INT95347 Negative_regulation of GRIN2B 1 0.57 0 1.19
144 INT101027 Binding of DST 20 0.41 10.9 1.17
145 INT76303 Negative_regulation of Positive_regulation of Hspb1 1 0.42 0.49 1.17
146 INT50389 Localization of Sptan1 3 0.73 0 1.16
147 INT80736 Protein_catabolism of Sptan1 5 0.32 3.32 1.1
148 INT143091 Positive_regulation of Negative_regulation of Grin2b 2 0.44 0.9 1.09
149 INT291961 Negative_regulation of Regulation of Grin2b 1 0.30 1.65 1.09
150 INT13397 Localization of DMD 21 0.78 7.96 1.08
151 INT66452 Positive_regulation of Cacna1c 6 0.19 2.56 1.08
152 INT231162 Localization of Dmd 6 0.71 2.27 1.07
153 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
154 INT199308 Gene_expression of Krt8 37 0.75 23.17 1.06
155 INT168957 Positive_regulation of CAV3 1 0.40 0 1.06
156 INT71498 Binding of Hspb1 7 0.42 7.38 1.05
157 INT71499 Localization of Hspb1 4 0.72 1.38 1.05
158 INT168960 Binding of CAV3 1 0.30 0 1.05
159 INT123962 Phosphorylation of Hspb1 8 0.82 2.08 1.04
160 INT83566 Negative_regulation of Adrbk2 2 0.23 0 1.03
161 INT71987 Regulation of Gene_expression of Sptan1 1 0.60 0 1.03
162 INT242171 Protein_catabolism of JUP 4 0.96 0.91 1.01
163 INT78645 Negative_regulation of Gene_expression of Psen2 1 0.14 0.13 1.01
164 INT138467 Gene_expression of Ryr2 5 0.55 2.36 0.98
165 INT125892 Regulation of Hspb1 2 0.48 4.28 0.98
166 INT71916 Gene_expression of TTN 9 0.75 1.69 0.97
167 INT78935 Localization of Cacna1c 3 0.48 1.25 0.97
168 INT71917 Gene_expression of ACTN1 4 0.24 2.27 0.96
169 INT84386 Positive_regulation of Positive_regulation of SRI 1 0.20 0 0.96
170 INT159986 Positive_regulation of Gene_expression of Sptan1 2 0.68 1.1 0.95
171 INT33217 Positive_regulation of Csrp3 1 0.08 0.85 0.95
172 INT24067 Negative_regulation of Hspb1 1 0.11 0.67 0.95
173 INT33218 Gene_expression of Csrp3 1 0.24 0.84 0.94
174 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
175 INT34597 Gene_expression of Des 10 0.75 2.54 0.93
176 INT192686 Positive_regulation of Positive_regulation of DMD 8 0.41 4.66 0.93
177 INT149903 Localization of Cav3 3 0.80 1.1 0.93
178 INT351265 Regulation of Binding of SRI 1 0.28 0 0.92
179 INT9797 Binding of Homer1 2 0.48 1.14 0.9
180 INT101056 Positive_regulation of GRIN2B 1 0.23 0.32 0.9
181 INT72151 Phosphorylation of MYOT 2 0.01 1.49 0.88
182 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
183 INT137551 Regulation of Pygm 2 0.01 1.59 0.87
184 INT186168 Negative_regulation of Negative_regulation of Grin2b 2 0.35 0.54 0.85
185 INT195056 Positive_regulation of Gene_expression of Pygm 2 0.04 1.99 0.83
186 INT78647 Positive_regulation of Localization of Psen2 1 0.16 0.14 0.83
187 INT167424 Positive_regulation of Pak1 1 0.14 1.43 0.83
188 INT143092 Negative_regulation of Negative_regulation of Grin2b 1 0.27 0.33 0.83
189 INT62155 Positive_regulation of Gene_expression of DMD 17 0.67 6.17 0.82
190 INT149905 Negative_regulation of Cav3 2 0.43 0.98 0.82
191 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
192 INT120353 Phosphorylation of DES 2 0.80 1.17 0.79
193 INT168661 Negative_regulation of Positive_regulation of SRI 1 0.02 0.37 0.79
194 INT94756 Positive_regulation of PSEN2 8 0.49 4.59 0.77
195 INT167381 Localization of DES 4 0.73 4.15 0.77
196 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
197 INT193849 Positive_regulation of Gene_expression of Psen2 5 0.44 4.92 0.76
198 INT202359 Binding of Nexn 4 0.08 1.43 0.76
199 INT165578 Regulation of Positive_regulation of Grin2b 3 0.41 1.07 0.74
200 INT114524 Binding of GRIN2B 3 0.36 0.44 0.74
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