GO:0030020

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Name extracellular matrix structural constituent conferring tensile strength
Categary Function
Go Slim No
Go Link GO:0030020
Unique Molecular Interactions 33
Total Molecular Interactions 40
Total Single Events 474
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for extracellular matrix structural constituent conferring tensile strength. They are ordered first by their pain relevance and then by number of times they were reported for extracellular matrix structural constituent conferring tensile strength. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54
2 INT312122 ELANE Positive_regulation of Protein_catabolism of COL2A1 1 0.05 0.65 0.39
3 INT264523 PTGDS Positive_regulation of Gene_expression of COL2A1 1 0.03 1.24 0.3
4 INT220194 PTGER2 Negative_regulation of COL2A1 1 0.26 0.55 0.29
5 INT60347 COL2A1 Positive_regulation of Gene_expression of Hras 1 0.05 0.92 0.2
6 INT220190 PTGER2 Regulation of COL2A1 1 0.32 0.92 0.18
7 INT220191 Binding of COL2A1 and PTGER2 1 0.22 0.35 0.18
8 INT293867 Binding of COL2A1 and MEFV 1 0.01 0.52 0.14
9 INT220213 Mmp13 Regulation of Protein_catabolism of COL2A1 1 0.49 0.29 0.14
10 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
11 INT279109 Binding of COL9A2 and MATN3 1 0.48 0.64 0.1
12 INT220195 PTGER2 Negative_regulation of Localization of COL2A1 1 0.26 0.51 0.09
13 INT245732 Binding of COL9A2 and DISC1 1 0.07 1.34 0.08
14 INT288003 Binding of COL2A1 and PADI1 1 0.09 0.11 0.06
15 INT220189 Binding of COL2A1 and TIMP1 1 0.04 0.1 0.05
16 INT323807 NFAT5 Regulation of Gene_expression of COL2A1 1 0.29 0.19 0.04
17 INT220196 Binding of PTGER2 and Negative_regulation of Gene_expression of COL2A1 1 0.26 0.77 0.04
18 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03
19 INT220245 IL1RN Regulation of Protein_catabolism of COL2A1 1 0.09 0 0.03
20 INT293869 Binding of COL2A1 and GREM1 1 0.00 1.11 0
21 INT288002 Binding of COL2A1 and GOPC 1 0.12 0 0
22 INT312230 INPP5K Regulation of Gene_expression of COL2A1 1 0.06 0 0
23 INT185848 Binding of COL11A2 and NTNG2 1 0.13 1.06 0
24 INT88567 COL2A1 Positive_regulation of A1cf 1 0.09 0.36 0
25 INT312227 INPP5K Regulation of Negative_regulation of COL2A1 1 0.06 0 0
26 INT245734 Binding of COL9A1 and COL9A2 1 0.26 0.52 0
27 INT312345 Binding of COL2A1 and COL5A2 1 0.00 1.21 0
28 INT323804 NFAT5 Regulation of Transcription of COL2A1 1 0.43 0.07 0
29 INT312213 INPP5K Regulation of COL2A1 1 0.06 0 0
30 INT245729 Binding of COL9A1 and COL9A3 1 0.29 0.52 0
31 INT238031 Binding of COL11A2 and OPLL 1 0.10 0.3 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for extracellular matrix structural constituent conferring tensile strength. They are ordered first by their pain relevance and then by number of times they were reported in extracellular matrix structural constituent conferring tensile strength. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58
2 INT130731 Protein_catabolism of COL2A1 47 0.96 21.86 9.28
3 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81
4 INT217742 Positive_regulation of Gene_expression of COL2A1 20 0.67 9.76 4.23
5 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47
6 INT130729 Negative_regulation of Protein_catabolism of COL2A1 15 0.42 7.59 3.35
7 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66
8 INT96693 Binding of COL2A1 45 0.46 37.11 2.61
9 INT117232 Localization of COL2A1 11 0.72 7.34 1.3
10 INT11658 Regulation of Gene_expression of COL2A1 9 0.62 3.09 1.11
11 INT9732 Regulation of COL2A1 9 0.58 6.93 0.44
12 INT279125 Binding of COL9A2 2 0.32 2.59 0.36
13 INT341659 Protein_catabolism of COL9A2 1 0.62 2.21 0.35
14 INT180577 Positive_regulation of Protein_catabolism of COL2A1 2 0.12 0.91 0.31
15 INT220209 Negative_regulation of Localization of COL2A1 1 0.41 0.48 0.29
16 INT220208 Regulation of Protein_catabolism of COL2A1 1 0.26 0.28 0.17
17 INT221000 Phosphorylation of COL2A1 1 0.19 0.18 0.12
18 INT245740 Binding of COL9A3 2 0.31 1.85 0.08
19 INT245754 Regulation of Positive_regulation of COL9A2 1 0.34 0.74 0.06
20 INT245747 Positive_regulation of Binding of COL9A3 1 0.42 1.05 0.06
21 INT245738 Positive_regulation of COL9A2 1 0.38 0.72 0.06
22 INT245750 Regulation of COL9A3 1 0.20 0.7 0.06
23 INT144618 Gene_expression of COL11A2 4 0.65 2.57 0.05
24 INT250505 Positive_regulation of Negative_regulation of COL2A1 1 0.41 0.57 0.05
25 INT272249 Negative_regulation of Negative_regulation of COL2A1 1 0.06 0 0.05
26 INT245751 Gene_expression of COL9A2 4 0.65 1.83 0.04
27 INT307323 Negative_regulation of Gene_expression of COL9A2 1 0.06 0.74 0.04
28 INT184729 Transcription of COL2A1 4 0.67 1.1 0
29 INT279126 Localization of COL9A2 2 0.64 0.77 0
30 INT165862 Positive_regulation of Binding of COL2A1 2 0.43 0 0
31 INT312246 Regulation of Negative_regulation of COL2A1 1 0.07 0 0
32 INT307327 Negative_regulation of Localization of COL9A2 1 0.06 0.35 0
33 INT245755 Gene_expression of COL9A3 1 0.57 0.54 0
34 INT132341 Negative_regulation of COL9A3 1 0.41 0.09 0
35 INT336845 Positive_regulation of COL9A3 1 0.05 1.42 0
36 INT185876 Binding of COL11A2 1 0.44 1.06 0
37 INT245739 Gene_expression of COL9A1 1 0.54 0.53 0
38 INT322897 Negative_regulation of Transcription of COL2A1 1 0.17 0 0
39 INT185906 Positive_regulation of Gene_expression of COL11A2 1 0.42 1.11 0
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