GO:0030036

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Name actin cytoskeleton organization
Categary Process
Go Slim No
Go Link GO:0030036
Unique Molecular Interactions 669
Total Molecular Interactions 878
Total Single Events 5812
Pain Genes Associated 99

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for actin cytoskeleton organization. They are ordered first by their pain relevance and then by number of times they were reported for actin cytoskeleton organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
2 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
3 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
4 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
5 INT146930 CAP1 Regulation of ABCB1 1 0.29 0.3 2.19
6 INT281381 FSCN1 Positive_regulation of Gene_expression of Gfap 1 0.06 1.13 1.98
7 INT134686 FSCN1 Positive_regulation of Gfap 1 0.00 0.71 1.89
8 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79
9 INT18786 Binding of Adra2a and Nisch 2 0.19 0 1.7
10 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
11 INT103592 CAP1 Negative_regulation of Gene_expression of CPOX 1 0.19 1.52 1.64
12 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
13 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
14 INT134679 FSCN1 Positive_regulation of MAPK8 1 0.01 0.56 1.39
15 INT281382 FSCN1 Positive_regulation of Sds 1 0.02 0.84 1.33
16 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
17 INT281383 FSCN1 Positive_regulation of Fig4 1 0.02 0.44 1.19
18 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19
19 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
20 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14
21 INT193288 CAP1 Positive_regulation of Pth 1 0.04 0.08 1.14
22 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
23 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08
24 INT93306 Binding of TRPV1 and CAP1 2 0.18 0.07 0.97
25 INT93307 CAP1 Positive_regulation of TRPV1 1 0.15 0.07 0.96
26 INT281380 Fos Negative_regulation of Gene_expression of FSCN1 1 0.07 0.4 0.96
27 INT182203 Binding of CXCL1 and CXCR2 1 0.14 1.25 0.95
28 INT166790 HRAS Negative_regulation of Gene_expression of PTGER1 1 0.01 1.46 0.95
29 INT182199 Binding of CXCR5 and CXCL1 1 0.16 1.24 0.94
30 INT182195 Binding of CXCL1 and CXCR4 1 0.13 1.25 0.94
31 INT281377 FSCN1 Positive_regulation of Gene_expression of Fos 1 0.08 0.49 0.93
32 INT182189 Binding of CXCL1 and CXCL13 1 0.14 1.24 0.93
33 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 0.09 0.18 0.93
34 INT193291 Binding of CAP1 and Cfd 1 0.02 0.13 0.91
35 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91
36 INT53152 Rac1 Regulation of Scg2 1 0.03 0 0.9
37 INT85783 PRKG1 Regulation of Prkcg 1 0.09 0.38 0.9
38 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 0.06 0.2 0.9
39 INT121701 HRAS Negative_regulation of MMP1 1 0.06 0.2 0.89
40 INT121704 HRAS Negative_regulation of MMP3 1 0.06 0.19 0.89
41 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
42 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 0.06 0.19 0.88
43 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
44 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
45 INT221257 Pde5a Positive_regulation of PRKG1 3 0.07 0.19 0.86
46 INT125234 Positive_regulation of Binding of BCR and CD40LG 1 0.31 0.76 0.86
47 INT125233 Binding of BCR and CD40LG 1 0.23 0.75 0.85
48 INT338695 CAP1 Regulation of Trpv1 1 0.01 0.14 0.85
49 INT94665 Nisch Negative_regulation of Maoa 1 0.07 0 0.83
50 INT63544 Adra2a Regulation of Nisch 1 0.18 0 0.79
51 INT128180 Gna12 Regulation of Regulation of RHOA 1 0.00 0 0.78
52 INT302119 Positive_regulation of Binding of Oprm1 and Ppp1r9b 1 0.02 0 0.77
53 INT152945 Dlg4 Regulation of Cap1 1 0.11 0.18 0.76
54 INT152946 Homer1 Regulation of Cap1 1 0.32 0.18 0.76
55 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
56 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72
57 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
58 INT338693 Aff3 Positive_regulation of Localization of CAP1 1 0.01 0.39 0.69
59 INT232617 Grid2ip Regulation of Cysltr1 1 0.03 0.58 0.68
60 INT354249 Binding of Mtap6 and Ppp1r9b 1 0.24 0.07 0.67
61 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
62 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
63 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 0.00 1.12 0.65
64 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
65 INT150965 NT5C2 Positive_regulation of PRKG1 1 0.04 0.07 0.62
66 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
67 INT247285 GLC1N Positive_regulation of Gene_expression of HRAS 1 0.02 1.3 0.61
68 INT193290 CAP1 Regulation of Fth1 1 0.02 0 0.6
69 INT193265 CAP1 Regulation of STH 1 0.00 0 0.6
70 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 0.05 0.05 0.59
71 INT193289 CAP1 Regulation of Pth 1 0.02 0 0.59
72 INT202971 Binding of BAG3 and CAP1 1 0.04 1.26 0.59
73 INT202973 Binding of CAP1 and CPP 1 0.05 1.24 0.58
74 INT202970 Binding of STC2 and CAP1 1 0.00 1.25 0.58
75 INT281378 FSCN1 Positive_regulation of Gene_expression of Fig4 1 0.02 0.22 0.56
76 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55
77 INT72387 Trim13 Regulation of Phosphorylation of Shc1 1 0.32 0.09 0.54
78 INT232618 Gene_expression of Grid2ip Regulation of Localization of Gria1 1 0.28 0.86 0.52
79 INT292075 FSCN1 Positive_regulation of Gene_expression of Csnk1a1 1 0.03 0.57 0.52
80 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
81 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
82 INT143922 TMSB4X Negative_regulation of Positive_regulation of Nfkb1 1 0.01 1.22 0.5
83 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 1 0.42 0.21 0.48
84 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 1 0.38 0.21 0.48
85 INT232619 Binding of Gria1 and Grid2ip 1 0.23 0.51 0.48
86 INT173475 Bcar1 Regulation of Isl1 1 0.01 0 0.47
87 INT296487 PRKG1 Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
88 INT155881 Binding of CDX2 and KRAS 1 0.40 1.51 0.47
89 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
90 INT92743 Binding of NF2 and LMOD1 1 0.00 0.08 0.46
91 INT95564 Positive_regulation of HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
92 INT341211 Gopc Regulation of Shc1 1 0.02 0.68 0.45
93 INT95562 HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
94 INT95563 HRAS Positive_regulation of TNF 1 0.03 0.7 0.45
95 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
96 INT338692 CAP1 Negative_regulation of Positive_regulation of Aff3 1 0.01 0.2 0.44
97 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
98 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43
99 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43
100 INT346218 Positive_regulation of Kras Positive_regulation of Phosphorylation of Mdk 1 0.01 0.71 0.42
101 INT247287 Gene_expression of GLC1N Regulation of Gene_expression of HRAS 1 0.02 0.56 0.42
102 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
103 INT131505 Rac1 Regulation of Gene_expression of Trpv1 1 0.55 0.39 0.42
104 INT92744 Binding of ADRB2 and NF2 1 0.00 0.1 0.41
105 INT257229 Binding of PRKG1 and Pde5a 1 0.01 0.17 0.41
106 INT351237 HRAS Regulation of CBL 1 0.00 0.48 0.4
107 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
108 INT118919 Binding of FRTS and Sh2b2 1 0.24 0 0.39
109 INT134167 Binding of ADRA2A and APLP1 1 0.09 0.64 0.39
110 INT166788 HRAS Negative_regulation of Phosphorylation of NFKB1 1 0.08 0.5 0.39
111 INT263433 Abl1 Regulation of Abl1 1 0.04 0.28 0.38
112 INT180442 Acot1 Positive_regulation of Rhoa 1 0.08 1.03 0.38
113 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37
114 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
115 INT85782 Rb1 Regulation of PRKG1 1 0.00 0.38 0.37
116 INT221259 Pde5a Positive_regulation of Localization of PRKG1 1 0.00 0.06 0.37
117 INT169646 Binding of Csrp1 and Il6 1 0.00 1.69 0.36
118 INT130974 Slc9a3r1 Positive_regulation of ASIC3 1 0.08 0.29 0.36
119 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
120 INT263383 Abl1 Regulation of Trib3 1 0.01 0.28 0.35
121 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
122 INT84085 Binding of Gucy1a2 and Nisch 1 0.00 0.22 0.35
123 INT71518 Binding of INSRR and Nisch 1 0.00 0.22 0.35
124 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
125 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
126 INT173476 Th Regulation of Gene_expression of Bcar1 1 0.10 0 0.34
127 INT23882 Npy Positive_regulation of Bcar1 1 0.34 0.67 0.34
128 INT20468 Ran Negative_regulation of Localization of Prl 1 0.30 0 0.33
129 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
130 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
131 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32
132 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32
133 INT295725 PTGER2 Positive_regulation of RAC2 1 0.05 1.92 0.32
134 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
135 INT316884 Positive_regulation of Binding of Cr2 and Bcr 1 0.06 0.86 0.31
136 INT316881 Positive_regulation of Binding of Cd19 and Bcr 1 0.08 0.86 0.31
137 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3
138 INT143688 Binding of Dlc1 and Trpv1 1 0.01 0.45 0.3
139 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3
140 INT316885 Binding of Cr2 and Bcr 1 0.06 0.85 0.3
141 INT316888 Binding of Cd19 and Bcr 1 0.08 0.85 0.3
142 INT166789 HRAS Regulation of Positive_regulation of NFKB1 1 0.05 0.31 0.3
143 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3
144 INT304536 Mknk1 Positive_regulation of PRKG1 1 0.03 0.53 0.3
145 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
146 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29
147 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29
148 INT265467 HRAS Negative_regulation of Gene_expression of PTGS2 1 0.01 0.84 0.29
149 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
150 INT346220 Binding of Kras and Braf 1 0.03 0.58 0.28
151 INT337161 Binding of Diap1 and Iqgap1 1 0.29 0.78 0.28
152 INT238632 Binding of EPB41 and Cask 1 0.44 0.78 0.27
153 INT213798 Sh2b2 Regulation of tf 1 0.12 0.53 0.27
154 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
155 INT213799 Sh2b2 Regulation of Tfeb 1 0.26 0.54 0.27
156 INT215279 Siglec1 Regulation of Rac2 1 0.01 0.74 0.27
157 INT224457 TNF Positive_regulation of Pdgfa 1 0.34 1.22 0.27
158 INT262354 TRIP10 Negative_regulation of Cyp4a3 1 0.00 0.8 0.26
159 INT109016 Negative_regulation of Prkg1 Negative_regulation of Positive_regulation of PRKG1 1 0.06 0.28 0.26
160 INT262353 TRIP10 Negative_regulation of Cyp1a2 1 0.03 0.8 0.26
161 INT262329 TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26
162 INT262330 Positive_regulation of TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26
163 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25
164 INT60524 IFNGR2 Positive_regulation of FERMT2 1 0.04 1.87 0.25
165 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
166 INT193031 CHRM2 Positive_regulation of ROCK1 1 0.00 0.12 0.24
167 INT193029 CHRM2 Positive_regulation of RHOA 1 0.01 0.12 0.24
168 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
169 INT140376 TGM1 Positive_regulation of Rhoa 1 0.01 0 0.24
170 INT312726 AASS Positive_regulation of FGD1 1 0.02 0.08 0.24
171 INT269561 TMPO Positive_regulation of RHOA 1 0.22 0 0.23
172 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
173 INT337158 Binding of Iqgap1 and Wasl 1 0.09 0.55 0.22
174 INT32735 ADRA2A Regulation of RTCA 1 0.07 0 0.22
175 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21
176 INT193035 Positive_regulation of PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
177 INT257397 Binding of FGD1 and INS 1 0.07 0.27 0.21
178 INT274578 Binding of ABL1 and PSTPIP1 1 0.07 1.55 0.21
179 INT193025 PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
180 INT193036 EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
181 INT193032 Positive_regulation of EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
182 INT213812 Sh2b2 Positive_regulation of Tfeb 1 0.44 0.45 0.2
183 INT60347 COL2A1 Positive_regulation of Gene_expression of Hras 1 0.05 0.92 0.2
184 INT257231 PRKG1 Negative_regulation of Ltp 1 0.07 0.07 0.2
185 INT257398 Binding of FGD1 and GHRH 1 0.03 0.27 0.2
186 INT257233 PRKG1 Positive_regulation of Phosphorylation of Creb1 1 0.01 0.09 0.2
187 INT145886 Binding of CXCL1 and Adipoq 1 0.00 0.77 0.2
188 INT143973 Rac1 Positive_regulation of Vti1b 1 0.00 0.16 0.2
189 INT343547 ROCK1 Positive_regulation of Gene_expression of PTHLH 1 0.15 0.2 0.2
190 INT180435 Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
191 INT180444 Positive_regulation of Acot1 Positive_regulation of Rhoa 1 0.08 0.43 0.19
192 INT299113 Binding of INPP5K and GOPC 1 0.18 2.69 0.19
193 INT180437 Positive_regulation of Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
194 INT332245 Pdgfa Positive_regulation of Stat6 1 0.07 1.22 0.19
195 INT66279 Binding of FLNB and HLA-B 1 0.41 0.57 0.19
196 INT355733 Pdgfb Regulation of Transcription of Bdnf 1 0.10 0.86 0.19
197 INT192333 PDGFA Positive_regulation of Gene_expression of FN1 2 0.11 1.26 0.18
198 INT303981 Lep Positive_regulation of Localization of CXCL1 1 0.02 0.34 0.18
199 INT193080 ROCK1 Positive_regulation of Ppp1r14a 1 0.00 0.13 0.18
200 INT103197 Nf1 Negative_regulation of ras 1 0.04 1.19 0.17

Single Events

The table below shows the top 100 pain related interactions that have been reported for actin cytoskeleton organization. They are ordered first by their pain relevance and then by number of times they were reported in actin cytoskeleton organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT129686 Gene_expression of FSCN1 46 0.15 18.91 34.47
2 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
3 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
4 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
5 INT104523 Positive_regulation of FSCN1 14 0.12 10.09 20.08
6 INT81210 Positive_regulation of PRKG1 71 0.70 26.83 19.89
7 INT104527 Binding of FSCN1 18 0.23 14.75 19.6
8 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
9 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
10 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14
11 INT27627 Binding of Rac1 41 0.41 22.88 13.68
12 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
13 INT76434 Negative_regulation of PRKG1 25 0.58 10.36 10.81
14 INT93309 Positive_regulation of CAP1 17 0.43 11.4 9.13
15 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
16 INT109724 Phosphorylation of FSCN1 5 0.07 3.15 8.82
17 INT89677 Gene_expression of PRKG1 38 0.78 13.98 8.56
18 INT93310 Gene_expression of CAP1 14 0.58 3.07 8.55
19 INT127691 Gene_expression of CXCL1 23 0.66 18.11 7.04
20 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
21 INT8541 Gene_expression of Csrp1 42 0.76 23.72 6.9
22 INT64671 Gene_expression of NISCH 10 0.69 2.19 6.9
23 INT8799 Negative_regulation of Csrp1 24 0.58 11.01 6.86
24 INT21138 Binding of ADRA2A 16 0.48 5.57 6.8
25 INT142065 Phosphorylation of CFL1 8 0.78 0.87 6.3
26 INT189177 Positive_regulation of Gene_expression of FSCN1 12 0.11 3.77 6.12
27 INT43524 Positive_regulation of Sh2b2 16 0.58 2.95 5.78
28 INT123563 Negative_regulation of Rock1 7 0.55 16.56 5.78
29 INT129685 Negative_regulation of FSCN1 7 0.05 3.44 5.69
30 INT120550 Negative_regulation of Rock1 27 0.42 18.38 5.66
31 INT116055 Phosphorylation of PRKG1 33 0.80 2.22 5.58
32 INT96778 Positive_regulation of Pdgfa 22 0.46 12.7 5.31
33 INT104342 Regulation of FSCN1 4 0.15 3.18 4.84
34 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
35 INT68216 Binding of NF1 40 0.48 51.24 4.59
36 INT1807 Negative_regulation of Bcar1 9 0.38 4.04 4.59
37 INT76433 Regulation of PRKG1 13 0.34 4.27 4.57
38 INT50713 Positive_regulation of Nisch 6 0.69 1.5 4.33
39 INT63113 Positive_regulation of HRAS 30 0.67 22.85 4.28
40 INT18785 Binding of Nisch 12 0.43 1.03 4.28
41 INT167174 Negative_regulation of Gene_expression of FSCN1 6 0.06 3.05 4.25
42 INT20981 Binding of HRAS 42 0.48 24.49 4.23
43 INT34184 Localization of FGD1 7 0.65 2.68 4.21
44 INT166966 Gene_expression of Ccr7 14 0.48 7.36 4.2
45 INT58875 Positive_regulation of FGD1 20 0.60 3.88 4.19
46 INT72385 Phosphorylation of Shc1 11 0.52 1.62 4.1
47 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
48 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97
49 INT96776 Positive_regulation of Gene_expression of Pdgfa 8 0.40 7.79 3.93
50 INT169475 Localization of HRAS 14 0.73 9.02 3.9
51 INT89678 Positive_regulation of Gene_expression of PRKG1 15 0.70 5.99 3.84
52 INT53594 Binding of Csrp1 5 0.32 11.87 3.84
53 INT92509 Regulation of Sh2b2 7 0.35 3.41 3.8
54 INT142066 Positive_regulation of Phosphorylation of CFL1 5 0.48 0.24 3.73
55 INT123564 Negative_regulation of Rock2 13 0.59 9.61 3.58
56 INT53706 Positive_regulation of Kras 13 0.67 9.26 3.57
57 INT193281 Binding of CAP1 7 0.07 4.57 3.53
58 INT96777 Localization of Pdgfa 12 0.79 5.86 3.52
59 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
60 INT55781 Regulation of Csrp1 11 0.34 6.87 3.36
61 INT48292 Negative_regulation of Sh2b2 9 0.26 2.14 3.26
62 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
63 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
64 INT58475 Localization of Rac1 12 0.75 5.94 3.2
65 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
66 INT117080 Localization of Csrp1 6 0.42 7.23 3.09
67 INT128179 Gene_expression of RHOA 7 0.64 2.48 3.01
68 INT51099 Negative_regulation of Nisch 6 0.43 0.97 2.93
69 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
70 INT61714 Binding of FGD1 12 0.35 7.72 2.91
71 INT72384 Positive_regulation of Phosphorylation of Shc1 1 0.32 0.48 2.9
72 INT15157 Gene_expression of INPP5K 30 0.67 15.49 2.85
73 INT158083 Gene_expression of FGD1 24 0.67 6.82 2.83
74 INT271599 Phosphorylation of Pdgfa 1 0.11 2.55 2.81
75 INT27260 Gene_expression of DYNLL1 8 0.75 7.72 2.78
76 INT22739 Positive_regulation of DYNLL1 5 0.67 1.69 2.67
77 INT62683 Negative_regulation of HRAS 19 0.57 7.93 2.65
78 INT182893 Gene_expression of Sh2b2 8 0.65 1.74 2.65
79 INT172963 Negative_regulation of Pdgfa 11 0.21 12.94 2.64
80 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
81 INT332774 Positive_regulation of Phosphorylation of FSCN1 1 0.02 0.69 2.63
82 INT146931 Regulation of CAP1 1 0.44 0.22 2.58
83 INT120551 Negative_regulation of Rock2 8 0.52 2.73 2.53
84 INT136681 Gene_expression of Shc1 13 0.77 9.67 2.52
85 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
86 INT262339 Positive_regulation of TRIP10 2 0.26 2.07 2.5
87 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
88 INT61378 Positive_regulation of Bcar1 13 0.45 2.84 2.45
89 INT223080 Binding of Pdgfa 8 0.18 7.21 2.44
90 INT61434 Regulation of Nf1 3 0.26 1.39 2.4
91 INT111039 Gene_expression of Kras 20 0.60 15.42 2.39
92 INT77983 Positive_regulation of Gene_expression of Csrp1 4 0.19 4.91 2.38
93 INT128174 Positive_regulation of Gene_expression of RHOA 7 0.36 1.5 2.36
94 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
95 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
96 INT64700 Binding of Nf1 14 0.45 15.24 2.29
97 INT86999 Regulation of DYNLL1 5 0.44 2.85 2.18
98 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
99 INT68277 Positive_regulation of CXCL1 6 0.56 6.98 2.14
100 INT22738 Negative_regulation of DYNLL1 17 0.57 6.68 2.06
101 INT142064 Negative_regulation of Phosphorylation of CFL1 3 0.56 0.42 2.06
102 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
103 INT76993 Regulation of HRAS 8 0.60 7.81 1.95
104 INT245945 Localization of CAP1 4 0.69 1.63 1.95
105 INT122534 Binding of Shc1 6 0.48 3.59 1.94
106 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93
107 INT113966 Negative_regulation of Nisch 2 0.31 0.76 1.93
108 INT308845 Gene_expression of Nisch 1 0.10 3.32 1.92
109 INT117980 Regulation of Rac1 10 0.45 3.72 1.88
110 INT23426 Regulation of ADRA2A 8 0.48 1.81 1.88
111 INT68181 Binding of Nf1 6 0.48 8.14 1.88
112 INT134097 Binding of CXCL1 1 0.17 1.35 1.88
113 INT126626 Positive_regulation of Rhoa 14 0.69 4.43 1.87
114 INT109015 Positive_regulation of Positive_regulation of PRKG1 5 0.38 2.04 1.87
115 INT130565 Localization of Nisch 1 0.71 0.17 1.86
116 INT308851 Regulation of Gene_expression of Nisch 1 0.04 2.35 1.86
117 INT232607 Gene_expression of Grid2ip 1 0.65 2.35 1.85
118 INT146193 Negative_regulation of Positive_regulation of Rhoa 3 0.42 3 1.84
119 INT99416 Negative_regulation of Bcar1 1 0.34 0.64 1.84
120 INT85348 Localization of RHOA 12 0.59 4.81 1.83
121 INT4188 Binding of NF2 7 0.46 3.52 1.79
122 INT126457 Gene_expression of BCL6 34 0.66 22.45 1.75
123 INT59790 Binding of BCR 16 0.36 15.34 1.75
124 INT104524 Localization of FSCN1 3 0.13 1.76 1.75
125 INT127692 Positive_regulation of Gene_expression of CXCL1 8 0.56 6.26 1.71
126 INT23881 Gene_expression of Bcar1 8 0.52 2.48 1.69
127 INT257820 Positive_regulation of PAFAH1B1 1 0.68 11.09 1.69
128 INT109975 Positive_regulation of Kras 14 0.45 12.72 1.68
129 INT254045 Gene_expression of TRIP10 4 0.29 3.04 1.67
130 INT263398 Positive_regulation of Abl1 1 0.60 1.44 1.66
131 INT136680 Negative_regulation of Gene_expression of Shc1 4 0.43 3.36 1.57
132 INT193284 Positive_regulation of Gene_expression of CAP1 1 0.07 0.05 1.55
133 INT43327 Positive_regulation of ADRA2A 3 0.46 1.54 1.53
134 INT93624 Negative_regulation of Kras 3 0.41 1.15 1.52
135 INT146190 Negative_regulation of Localization of Rhoa 4 0.42 1.64 1.5
136 INT104691 Positive_regulation of Localization of CXCL1 1 0.06 2.69 1.48
137 INT235954 Gene_expression of Bcr 1 0.13 6.77 1.47
138 INT184206 Protein_catabolism of HRAS 22 0.66 7.86 1.46
139 INT113659 Gene_expression of ABR 19 0.65 8.49 1.45
140 INT42391 Positive_regulation of BCR 7 0.49 4.93 1.44
141 INT135611 Negative_regulation of Gene_expression of CXCL1 3 0.48 4.07 1.44
142 INT66708 Negative_regulation of NISCH 2 0.38 3.1 1.43
143 INT232604 Localization of Grid2ip 1 0.72 1.33 1.43
144 INT114490 Gene_expression of PDLIM7 17 0.78 11.35 1.42
145 INT136678 Positive_regulation of Gene_expression of Shc1 4 0.50 2.93 1.42
146 INT159186 Positive_regulation of Gene_expression of DYNLL1 1 0.49 1.25 1.4
147 INT116056 Positive_regulation of Phosphorylation of PRKG1 8 0.33 0.27 1.37
148 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
149 INT117394 Positive_regulation of Gene_expression of NISCH 3 0.45 0.41 1.35
150 INT117081 Positive_regulation of Localization of Csrp1 2 0.28 2.43 1.35
151 INT156993 Localization of PRKG1 6 0.35 1.06 1.34
152 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32
153 INT78949 Positive_regulation of Nisch 3 0.18 0.57 1.3
154 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29
155 INT142992 Phosphorylation of RHOA 3 0.80 0.87 1.28
156 INT128176 Regulation of RHOA 13 0.44 4.35 1.26
157 INT131645 Negative_regulation of Nf1 10 0.58 8.12 1.24
158 INT83032 Regulation of NISCH 2 0.55 1.2 1.24
159 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23
160 INT268027 Regulation of Gene_expression of FSCN1 3 0.03 0.64 1.23
161 INT168720 Regulation of Negative_regulation of Rock1 1 0.43 1.31 1.23
162 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22
163 INT111859 Regulation of Rhoa 3 0.61 0.23 1.22
164 INT67308 Positive_regulation of NISCH 3 0.62 1.21 1.22
165 INT16013 Gene_expression of Rac1 52 0.75 23.79 1.21
166 INT60060 Positive_regulation of KRAS 17 0.67 11.68 1.21
167 INT98062 Regulation of Gene_expression of Rac1 4 0.39 1.41 1.21
168 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
169 INT343806 Gene_expression of CORO7 3 0.57 2.54 1.18
170 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17
171 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
172 INT143846 Positive_regulation of INPP5K 5 0.40 6.4 1.17
173 INT105865 Regulation of Gene_expression of PRKG1 4 0.12 1.82 1.15
174 INT176317 Transcription of CAP1 3 0.16 1.8 1.15
175 INT152010 Positive_regulation of Ccr7 3 0.47 1.46 1.15
176 INT180095 Gene_expression of Rock1 22 0.55 4.9 1.14
177 INT126534 Negative_regulation of ROCK1 18 0.49 14.32 1.13
178 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13
179 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12
180 INT354243 Negative_regulation of Ppp1r9b 1 0.28 0.28 1.12
181 INT166171 Negative_regulation of Gene_expression of HRAS 5 0.07 3.98 1.11
182 INT146198 Positive_regulation of Rock1 16 0.49 5.86 1.1
183 INT102758 Negative_regulation of Abl1 2 0.51 1.13 1.1
184 INT146553 Positive_regulation of Rock2 4 0.44 2.56 1.09
185 INT263403 Positive_regulation of Rock1 3 0.38 4.68 1.09
186 INT111858 Regulation of Rock1 1 0.41 0.75 1.09
187 INT28809 Regulation of CXCL1 3 0.53 3.21 1.07
188 INT136044 Gene_expression of Rock2 7 0.78 0.19 1.06
189 INT196276 Regulation of Phosphorylation of PRKG1 6 0.27 0 1.06
190 INT150938 Regulation of Nisch 2 0.45 0.8 1.05
191 INT136817 Negative_regulation of Positive_regulation of RHOA 8 0.57 0 1.04
192 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
193 INT93044 Negative_regulation of Gene_expression of Csrp1 2 0.58 2.17 1.03
194 INT247294 Regulation of Gene_expression of HRAS 1 0.04 1.8 1.02
195 INT204058 Regulation of Gene_expression of Kras 4 0.24 7.54 1.01
196 INT12976 Negative_regulation of ADRA2A 4 0.50 0.16 1.01
197 INT181354 Binding of Ccr7 2 0.23 1.94 1.01
198 INT257824 Localization of PAFAH1B1 1 0.74 6.58 1
199 INT67174 Negative_regulation of Rac1 22 0.56 10.72 0.99
200 INT111035 Positive_regulation of Gene_expression of Kras 5 0.31 3.31 0.99
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