GO:0030072

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Name peptide hormone secretion
Categary Process
Go Slim No
Go Link GO:0030072
Unique Molecular Interactions 312
Total Molecular Interactions 459
Total Single Events 3106
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for peptide hormone secretion. They are ordered first by their pain relevance and then by number of times they were reported for peptide hormone secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
2 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
3 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
4 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
5 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
6 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
7 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
8 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
9 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
10 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
11 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
12 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
13 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
14 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82
15 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
16 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
17 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
18 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
19 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
20 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
21 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
22 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
23 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
24 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
25 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
26 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
27 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
28 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
29 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
30 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
31 INT131642 Edn1 Positive_regulation of Positive_regulation of Insrr 1 0.01 0.44 0.6
32 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
33 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
34 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
35 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
36 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
37 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
38 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
39 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
40 INT94018 Binding of EDN2 and EDN3 1 0.19 0 0.48
41 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
42 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
43 INT50497 Edn1 Positive_regulation of Pla2g1b 1 0.01 0.23 0.45
44 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
45 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
46 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
47 INT153766 Edn1 Positive_regulation of Gtf3a 1 0.04 1.25 0.41
48 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
49 INT99399 Penk Positive_regulation of Edn1 1 0.00 0 0.38
50 INT99400 Gast Positive_regulation of Edn1 1 0.00 0 0.38
51 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37
52 INT313701 Calca Negative_regulation of Binding of Edn1 1 0.30 0.14 0.37
53 INT152314 Il18 Regulation of Edn1 1 0.02 0.22 0.36
54 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
55 INT152316 Ifng Regulation of Edn1 1 0.01 0.22 0.35
56 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
57 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
58 INT207576 RETN Positive_regulation of Gene_expression of EDN1 1 0.05 0.78 0.33
59 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
60 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32
61 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
62 INT182262 EDN1 Positive_regulation of Gene_expression of NOS2 1 0.28 0.79 0.31
63 INT99843 Edn3 Negative_regulation of Localization of Ren 1 0.25 0.42 0.31
64 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31
65 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
66 INT54639 Edn3 Negative_regulation of Edn2 1 0.00 0 0.28
67 INT72820 EDN3 Positive_regulation of Avp 1 0.31 0.64 0.27
68 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26
69 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
70 INT178095 EDN1 Positive_regulation of MMP3 1 0.04 0.88 0.24
71 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24
72 INT178085 EDN1 Positive_regulation of MMP7 1 0.06 0.89 0.24
73 INT178141 EDN1 Positive_regulation of Timp1 1 0.30 0.89 0.24
74 INT178075 EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
75 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 0.05 0.83 0.24
76 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
77 INT178142 EDN1 Positive_regulation of Localization of Timp1 1 0.28 0.89 0.24
78 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24
79 INT182272 EDN1 Regulation of Gene_expression of MMP13 1 0.26 0.87 0.22
80 INT91686 Mb Positive_regulation of Edn1 1 0.03 0.29 0.22
81 INT182265 EDN1 Positive_regulation of NOS2 1 0.24 0.56 0.22
82 INT182263 EDN1 Positive_regulation of MMP1 1 0.15 0.43 0.21
83 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
84 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2
85 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
86 INT182258 EDN1 Positive_regulation of Positive_regulation of MMP1 1 0.15 0.47 0.19
87 INT182271 EDN1 Positive_regulation of Localization of MMP13 1 0.27 0.47 0.19
88 INT219915 Edn1 Regulation of Positive_regulation of Trpv1 1 0.33 0 0.18
89 INT140096 Gtf3a Positive_regulation of Gene_expression of Edn1 1 0.02 0.44 0.18
90 INT171386 Edn1 Positive_regulation of Mapk1 1 0.05 0.13 0.18
91 INT60778 Edn1 Positive_regulation of EDNRA 1 0.00 0 0.18
92 INT284450 Edn1 Positive_regulation of Gene_expression of MMP9 1 0.01 0.3 0.18
93 INT140094 Ifng Regulation of Gene_expression of Edn1 1 0.18 0.44 0.18
94 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17
95 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
96 INT203759 Binding of EDN1 and TNF 1 0.16 0.71 0.16
97 INT94017 Binding of EDN3 and INSRR 1 0.03 0 0.16
98 INT324899 Edn1 Positive_regulation of Positive_regulation of Mmp9 1 0.10 0.66 0.16
99 INT94022 Positive_regulation of Binding of EDN1 and INSRR 1 0.06 0 0.16
100 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.91 0.16
101 INT94021 Binding of EDN1 and EDN2 1 0.26 0 0.16
102 INT94014 Positive_regulation of Binding of EDN1 and EDN3 1 0.36 0 0.16
103 INT94023 Positive_regulation of Binding of EDN2 and EDN3 1 0.25 0 0.16
104 INT94019 Positive_regulation of Binding of EDN3 and INSRR 1 0.04 0 0.16
105 INT324894 Edn1 Positive_regulation of Gene_expression of Mmp3 1 0.07 0.66 0.16
106 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15
107 INT21509 Agt Regulation of Edn1 1 0.53 0 0.15
108 INT182261 EDN1 Regulation of Gene_expression of MMP1 1 0.17 0.7 0.15
109 INT50500 Edn1 Positive_regulation of PTGS1 1 0.00 0.07 0.14
110 INT324898 Ece1 Regulation of Gene_expression of Edn1 1 0.17 0.8 0.14
111 INT161799 Positive_regulation of Binding of ECE1 and EDN1 1 0.07 0.68 0.14
112 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14
113 INT72818 Edn3 Negative_regulation of Avp 1 0.08 0.34 0.14
114 INT72819 Regulation of EDN3 Positive_regulation of Avp 1 0.28 0.32 0.13
115 INT161798 Positive_regulation of Binding of EDN1 and ING1 1 0.06 0.66 0.13
116 INT161800 Binding of EDN1 and ING1 1 0.05 0.65 0.13
117 INT178083 EDN1 Positive_regulation of Gene_expression of VEGFA 1 0.09 1.8 0.13
118 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12
119 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
120 INT77863 EDN1 Positive_regulation of POMC 1 0.50 0.34 0.12
121 INT182273 EDN1 Regulation of Gene_expression of BAD 1 0.11 0.73 0.12
122 INT317162 Binding of Bdnf and Htt 1 0.51 0.2 0.12
123 INT180445 Edn1 Positive_regulation of Rhoa 1 0.08 0.57 0.11
124 INT222507 Igf1 Positive_regulation of Localization of Edn3 1 0.05 0 0.11
125 INT319315 Binding of Ap2a2 and Htt 1 0.28 0.64 0.11
126 INT182270 EDN1 Positive_regulation of Gene_expression of MMP1 1 0.18 0.55 0.1
127 INT181569 Binding of Edn1 and Mapk8 1 0.09 2.7 0.1
128 INT181570 Binding of Edn1 and Mapk1 1 0.13 2.72 0.1
129 INT6674 Edn1 Positive_regulation of Gene_expression of FOS 1 0.08 0.19 0.1
130 INT139476 Edn1 Positive_regulation of Ednra 1 0.00 1.07 0.1
131 INT10904 Edn1 Regulation of Localization of Nppb 1 0.22 0.54 0.1
132 INT92956 Edn1 Regulation of Positive_regulation of Nos2 1 0.18 0.17 0.09
133 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 0.10 0.57 0.09
134 INT230750 Crp Positive_regulation of Edn1 1 0.10 0.27 0.09
135 INT92957 Edn1 Regulation of Gene_expression of Nos2 1 0.18 0.17 0.09
136 INT178072 Gene_expression of EDNRB Positive_regulation of EDN3 1 0.05 1.11 0.08
137 INT242257 Binding of EDN1 and ELF3 1 0.17 0.21 0.08
138 INT181584 Binding of EDNRB and Edn1 1 0.46 0.85 0.08
139 INT181583 Binding of Edn1 and Positive_regulation of NOS1 1 0.02 0.86 0.08
140 INT178100 Gene_expression of EDNRB Positive_regulation of EDN1 1 0.17 1.11 0.08
141 INT113369 Edn1 Regulation of Adarb1 1 0.02 0.14 0.08
142 INT178081 Negative_regulation of EDN1 Positive_regulation of HIF1A 1 0.04 1.18 0.08
143 INT178080 EDN1 Positive_regulation of HIF1A 1 0.05 1.05 0.08
144 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07
145 INT182269 EDN1 Positive_regulation of Localization of MMP1 1 0.17 0.31 0.07
146 INT192908 Edn1 Positive_regulation of Ednra 1 0.21 0.35 0.07
147 INT242258 ELF3 Negative_regulation of EDN1 1 0.15 0.09 0.07
148 INT309941 Edn1 Positive_regulation of Tlr2 1 0.02 1.31 0.07
149 INT178093 EDN3 Positive_regulation of Gene_expression of EDNRB 1 0.05 1.01 0.07
150 INT172382 AGT Positive_regulation of Localization of EDN1 1 0.03 0.34 0.07
151 INT182268 Negative_regulation of MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
152 INT192907 Edn1 Positive_regulation of Ednrb 1 0.10 0.35 0.07
153 INT182274 MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
154 INT191219 Edn1 Positive_regulation of Amigo2 1 0.06 1.26 0.07
155 INT324896 Ece1 Positive_regulation of Negative_regulation of Edn1 1 0.19 0.42 0.07
156 INT172381 AVP Positive_regulation of Localization of EDN1 1 0.01 0.34 0.07
157 INT178096 EDN1 Positive_regulation of Gene_expression of EDNRB 1 0.17 1.01 0.07
158 INT181645 Edn1 Positive_regulation of NOS3 1 0.02 0.21 0.07
159 INT178090 EDN1 Positive_regulation of Phosphorylation of GJA1 1 0.09 0.88 0.06
160 INT302980 Mmp2 Positive_regulation of Smpd3 1 0.29 0.78 0.05
161 INT191216 Binding of Edn1 and Cotl1 1 0.14 0.63 0.05
162 INT182259 EDN1 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.27 0.05
163 INT180668 Edn1 Positive_regulation of Gene_expression of Col1a1 1 0.02 0 0.05
164 INT182264 EDN1 Positive_regulation of Positive_regulation of MAPK14 1 0.26 0.1 0.05
165 INT317181 Binding of Htt and Uts2r 1 0.04 0 0.05
166 INT180667 Edn1 Regulation of Ecm1 1 0.04 0 0.05
167 INT213263 INS Positive_regulation of EDN1 1 0.12 0.54 0.04
168 INT178091 EDN1 Positive_regulation of Gene_expression of PTGER2 1 0.01 0.74 0.04
169 INT353314 Edn1 Positive_regulation of Kalrn 1 0.03 0.21 0.04
170 INT229371 Positive_regulation of Pparg Negative_regulation of Gene_expression of Edn1 1 0.01 0.92 0.04
171 INT178098 EDN1 Positive_regulation of Transcription of VEGFA 1 0.08 0.76 0.04
172 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04
173 INT306513 EDN3 Positive_regulation of EDNRB 1 0.14 0.98 0.04
174 INT302982 Smpd1 Positive_regulation of Gene_expression of Smpd3 1 0.30 0.64 0.04
175 INT306514 EDN1 Positive_regulation of EDNRB 1 0.11 0.98 0.04
176 INT353317 Edn1 Positive_regulation of RHOA 1 0.19 0.16 0.04
177 INT178082 EDN1 Positive_regulation of VEGFA 1 0.08 0.77 0.04
178 INT306527 Binding of Htt and Aifm1 1 0.20 0.82 0.04
179 INT323623 Binding of Adm and Edn1 1 0.04 0.77 0.03
180 INT317161 Htt Regulation of Transcription of Bdnf 1 0.48 0.41 0.03
181 INT239229 Regulation of Binding of Edn1 and Ednra 1 0.01 0.37 0.03
182 INT321407 EDN1 Positive_regulation of Phosphorylation of IRS1 1 0.06 1.07 0.03
183 INT345298 NLRP3 Positive_regulation of Localization of Edn1 1 0.01 0.94 0.03
184 INT256228 EDNRB Positive_regulation of EDN1 1 0.26 0.62 0.03
185 INT239225 Binding of Edn1 and Ednrb 1 0.02 0.36 0.03
186 INT292081 Binding of EDN1 and NCOR2 1 0.00 0.98 0.03
187 INT239228 Regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03
188 INT200311 Htt Positive_regulation of Rest 1 0.05 0.75 0.03
189 INT239224 Positive_regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03
190 INT213030 Hdl1 Regulation of Gene_expression of Edn1 1 0.06 0.88 0
191 INT10901 Edn1 Positive_regulation of Localization of Nppb 1 0.39 0.68 0
192 INT6676 Binding of Edn1 and Regulation of Gene_expression of CREB1 1 0.04 0.15 0
193 INT10909 Edn1 Positive_regulation of Nppb 1 0.39 0.16 0
194 INT186689 Binding of ACHE and Edn1 1 0.28 0 0
195 INT14790 Nppa Regulation of Edn3 1 0.45 0.7 0
196 INT186685 Edn1 Regulation of Gene_expression of Il6 1 0.11 1.1 0
197 INT284143 EDN1 Positive_regulation of CA2 1 0.03 0.37 0
198 INT121179 Binding of Htt and Rest 1 0.07 0.45 0
199 INT192910 Edn1 Regulation of Col4a1 1 0.16 0.49 0
200 INT309515 Xrcc6 Regulation of Gene_expression of Htt 1 0.32 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for peptide hormone secretion. They are ordered first by their pain relevance and then by number of times they were reported in peptide hormone secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
2 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
3 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
4 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
5 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
6 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
7 INT5048 Binding of Edn1 55 0.47 18.86 19.16
8 INT9191 Localization of EDN1 94 0.81 57.01 14.78
9 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
10 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
11 INT6365 Localization of Edn1 56 0.81 18.84 13.83
12 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
13 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
14 INT6361 Localization of Edn1 30 0.81 19.09 9.7
15 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
16 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
17 INT10237 Binding of EDN1 40 0.48 16 8.48
18 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
19 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
20 INT17803 Regulation of Edn1 14 0.54 4.75 4.71
21 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
22 INT5782 Gene_expression of Edn3 17 0.67 3.38 3.65
23 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
24 INT55033 Localization of Edn3 7 0.80 1.4 3.05
25 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
26 INT53374 Binding of Edn1 17 0.43 11.66 2.98
27 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
28 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
29 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
30 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
31 INT76834 Negative_regulation of Gene_expression of Edn1 4 0.43 1.76 1.88
32 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
33 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76
34 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
35 INT14842 Negative_regulation of Binding of EDN1 4 0.57 0.67 1.66
36 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
37 INT15407 Positive_regulation of Positive_regulation of Edn1 5 0.62 3.69 1.49
38 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
39 INT65640 Positive_regulation of Localization of Edn1 2 0.42 2.16 1.48
40 INT17802 Transcription of Edn1 6 0.24 6.31 1.18
41 INT302938 Gene_expression of Smpd3 1 0.78 16.18 1.17
42 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12
43 INT108997 Localization of Htt 28 0.77 3.76 1.07
44 INT69803 Regulation of Localization of Edn1 3 0.62 0.79 0.98
45 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
46 INT49255 Protein_catabolism of EDN1 5 0.99 2.66 0.95
47 INT69422 Positive_regulation of Negative_regulation of EDN1 2 0.43 0.96 0.95
48 INT49254 Transcription of EDN1 5 0.69 2.42 0.94
49 INT302945 Positive_regulation of Smpd3 1 0.70 9.99 0.93
50 INT152081 Phosphorylation of Edn1 1 0.53 0.39 0.9
51 INT61591 Negative_regulation of Localization of EDN1 11 0.59 2.09 0.85
52 INT6243 Regulation of Edn3 2 0.35 0.2 0.83
53 INT154886 Gene_expression of Htt 18 0.76 15.51 0.82
54 INT57433 Positive_regulation of Binding of EDN1 3 0.49 0.62 0.82
55 INT61122 Regulation of Regulation of Edn3 1 0.35 0.2 0.75
56 INT61121 Regulation of Regulation of Edn1 1 0.43 0.2 0.75
57 INT59970 Positive_regulation of Binding of Edn1 2 0.40 1.11 0.71
58 INT63556 Binding of Edn3 1 0.24 0.63 0.7
59 INT21957 Negative_regulation of Negative_regulation of Edn1 5 0.43 1.34 0.69
60 INT49252 Positive_regulation of Localization of EDN1 17 0.69 6.55 0.66
61 INT100396 Transcription of Edn1 7 0.69 2.48 0.66
62 INT50061 Negative_regulation of Edn3 4 0.58 0.77 0.65
63 INT49256 Regulation of Positive_regulation of EDN1 2 0.45 2.5 0.65
64 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6
65 INT287206 Regulation of Gene_expression of Htt 6 0.50 3.27 0.57
66 INT7153 Positive_regulation of Regulation of Edn1 2 0.35 1.97 0.57
67 INT135715 Negative_regulation of Localization of Edn1 5 0.42 1.7 0.56
68 INT215340 Localization of Htt 10 0.61 5.12 0.55
69 INT63910 Regulation of Positive_regulation of Edn1 2 0.43 0.64 0.54
70 INT287204 Protein_catabolism of Htt 6 0.99 2.8 0.53
71 INT131641 Negative_regulation of Negative_regulation of Edn1 1 0.37 0.31 0.52
72 INT181581 Regulation of Positive_regulation of Edn1 4 0.23 3.76 0.51
73 INT119230 Negative_regulation of Htt 5 0.42 2.99 0.5
74 INT55372 Regulation of Localization of Edn1 2 0.38 0.64 0.46
75 INT243418 Binding of Htt 14 0.30 5.94 0.44
76 INT165597 Positive_regulation of Htt 8 0.60 4.27 0.44
77 INT55370 Positive_regulation of Localization of Edn3 2 0.47 1.13 0.44
78 INT57434 Regulation of Regulation of EDN1 1 0.40 0.47 0.44
79 INT92195 Negative_regulation of Edn3 3 0.43 1.92 0.43
80 INT132864 Binding of Htt 15 0.46 2.34 0.38
81 INT81433 Negative_regulation of Positive_regulation of Edn1 4 0.39 0.81 0.38
82 INT168066 Transcription of Edn3 1 0.38 0.87 0.38
83 INT8664 Positive_regulation of EDN3 2 0.38 0 0.37
84 INT287207 Regulation of Protein_catabolism of Htt 3 0.45 1.73 0.35
85 INT129487 Negative_regulation of EDN3 1 0.38 0.35 0.35
86 INT113368 Regulation of Negative_regulation of Edn1 1 0.45 0.71 0.35
87 INT141013 Regulation of Gene_expression of Edn1 2 0.24 0.55 0.34
88 INT53375 Binding of Edn3 1 0.36 0 0.32
89 INT16368 Protein_catabolism of Edn1 2 0.72 0.18 0.31
90 INT131110 Localization of EDN3 1 0.03 0.74 0.31
91 INT131109 Positive_regulation of Localization of EDN3 1 0.02 0.76 0.31
92 INT302947 Negative_regulation of Gene_expression of Smpd3 1 0.43 3.76 0.31
93 INT16366 Gene_expression of Edn3 4 0.49 1.35 0.29
94 INT254877 Positive_regulation of Gene_expression of Htt 15 0.64 6.29 0.28
95 INT84038 Protein_catabolism of Edn1 2 0.86 0.69 0.26
96 INT302956 Localization of Smpd3 1 0.75 2.92 0.24
97 INT287205 Regulation of Htt 5 0.45 3.56 0.22
98 INT302952 Negative_regulation of Smpd3 1 0.43 2.57 0.22
99 INT8665 Positive_regulation of Positive_regulation of EDN3 1 0.38 0 0.22
100 INT67265 Positive_regulation of Negative_regulation of Edn1 1 0.61 0.05 0.21
101 INT156920 Phosphorylation of EDN1 4 0.61 0.66 0.19
102 INT53376 Positive_regulation of Regulation of Edn3 1 0.48 0 0.19
103 INT53372 Positive_regulation of Regulation of Edn1 1 0.50 0 0.19
104 INT100397 Regulation of Transcription of Edn1 1 0.00 0.1 0.19
105 INT53373 Regulation of Edn3 2 0.45 1.38 0.18
106 INT55371 Positive_regulation of Edn3 1 0.69 0.38 0.14
107 INT284152 Regulation of Transcription of EDN1 1 0.32 0.44 0.13
108 INT6362 Negative_regulation of Localization of Edn1 3 0.16 1.92 0.12
109 INT15391 Negative_regulation of Positive_regulation of Edn1 2 0.07 0.1 0.1
110 INT170744 Positive_regulation of Transcription of Edn1 2 0.20 1.3 0.1
111 INT302948 Negative_regulation of Binding of Smpd3 1 0.43 1.54 0.1
112 INT302940 Binding of Smpd3 1 0.37 1.53 0.1
113 INT49257 Positive_regulation of Transcription of EDN1 2 0.46 1.1 0.08
114 INT126441 Negative_regulation of Transcription of Edn1 1 0.40 0.17 0.08
115 INT287203 Negative_regulation of Gene_expression of Htt 7 0.37 5.08 0.07
116 INT178109 Binding of EDN3 1 0.06 1.65 0.07
117 INT302969 Positive_regulation of Positive_regulation of Smpd3 1 0.50 1.27 0.06
118 INT261890 Positive_regulation of Gene_expression of Htt 1 0.43 0.85 0.06
119 INT317175 Positive_regulation of Localization of Htt 1 0.48 0 0.05
120 INT306521 Transcription of Htt 1 0.69 4.13 0.05
121 INT331204 Negative_regulation of Binding of Htt 1 0.04 0.64 0.04
122 INT261891 Negative_regulation of Gene_expression of Htt 1 0.37 1.12 0.04
123 INT302965 Regulation of Positive_regulation of Smpd3 1 0.27 0.78 0.03
124 INT302943 Regulation of Smpd3 1 0.45 1.35 0.03
125 INT270323 Gene_expression of EDN3 1 0.01 0.76 0.03
126 INT154887 Transcription of Htt 3 0.66 0 0
127 INT261886 Regulation of Htt 2 0.43 2.06 0
128 INT313014 Positive_regulation of Binding of Htt 2 0.13 0.91 0
129 INT341938 Positive_regulation of Negative_regulation of Htt 1 0.07 0.65 0
130 INT254883 Negative_regulation of Positive_regulation of Htt 1 0.05 1.14 0
131 INT317177 Negative_regulation of Transcription of Htt 1 0.41 0 0
132 INT226251 Protein_catabolism of EDN3 1 0.02 0 0
133 INT22196 Positive_regulation of Gene_expression of Edn3 1 0.17 0.15 0
134 INT280682 Positive_regulation of Transcription of Edn1 1 0.34 0 0
135 INT49261 Negative_regulation of Protein_catabolism of EDN1 1 0.58 0 0
136 INT309469 Negative_regulation of Localization of Htt 1 0.34 0.13 0
137 INT317170 Regulation of Binding of Htt 1 0.43 0 0
138 INT181578 Negative_regulation of Phosphorylation of Edn1 1 0.37 0.1 0
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