GO:0030073

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Name insulin secretion
Categary Process
Go Slim No
Go Link GO:0030073
Unique Molecular Interactions 490
Total Molecular Interactions 667
Total Single Events 4935
Pain Genes Associated 45

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for insulin secretion. They are ordered first by their pain relevance and then by number of times they were reported for insulin secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
2 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
3 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 0.07 1.72 2.46
4 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
5 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
6 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44
7 INT81788 Binding of AGRP and MC4R 4 0.51 0 1.09
8 INT331108 Mc1r Positive_regulation of Mc4r 1 0.44 1.05 1.06
9 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
10 INT166842 Binding of ANXA1 and Nfkb1 1 0.37 1.64 0.95
11 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
12 INT161769 Cck Regulation of Cckar 1 0.27 0.53 0.92
13 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91
14 INT151630 Il1rn Negative_regulation of Dock9 1 0.03 1.33 0.88
15 INT115655 Glp1r Positive_regulation of Ins1 1 0.42 0 0.84
16 INT84102 B3GAT1 Positive_regulation of Localization of Glp1r 1 0.09 0 0.83
17 INT187226 Vip Positive_regulation of Gene_expression of Il1rn 1 0.04 0.96 0.82
18 INT78348 Binding of GALR1 and GAL 4 0.41 1.47 0.8
19 INT150680 Pomc Negative_regulation of Gene_expression of Eif2ak3 1 0.35 0.07 0.8
20 INT56499 Neurod1 Positive_regulation of Maoa 1 0.47 0 0.8
21 INT18402 Glp1r Regulation of Localization of Sst 1 0.19 0 0.77
22 INT111194 Binding of NEUROD1 and Pck1 1 0.39 0 0.75
23 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
24 INT123077 Cacna1c Negative_regulation of Gene_expression of Dbi 1 0.05 0.71 0.7
25 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
26 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69
27 INT326586 SLC18A2 Negative_regulation of DDC 1 0.28 0.91 0.66
28 INT335456 Binding of PDX1 and hb 1 0.02 2.59 0.66
29 INT154263 NEUROD1 Positive_regulation of Gene_expression of GAL 1 0.50 0.06 0.63
30 INT279398 Binding of IL1RN and Il1rn 1 0.00 0.51 0.63
31 INT255994 Binding of Ang and Il1rn 1 0.09 1.21 0.63
32 INT255997 Binding of Il1rn and H7 1 0.01 1.21 0.63
33 INT257717 Binding of Bdnf and Vgf 1 0.25 0.86 0.61
34 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
35 INT257715 Bdnf Positive_regulation of Transcription of Vgf 1 0.35 0.66 0.57
36 INT143938 Il1rn Negative_regulation of Il1b 1 0.04 0.52 0.57
37 INT185809 Binding of PDX1 and SPP1 1 0.02 1.69 0.57
38 INT143940 Il1rn Negative_regulation of Il1f5 1 0.00 0.51 0.57
39 INT257713 Ngf Positive_regulation of Transcription of Vgf 1 0.41 0.66 0.57
40 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
41 INT14387 GAL Regulation of TAC1 1 0.10 0 0.56
42 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56
43 INT166840 Binding of Anxa1 and Nfkb1 1 0.26 0.82 0.56
44 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
45 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55
46 INT108021 Binding of Pomc and Mc4r 1 0.00 0.97 0.55
47 INT85265 Binding of Il1rn and Insrr 1 0.01 0 0.54
48 INT171896 Binding of Ifnar1 and Il1rn 1 0.00 0.81 0.54
49 INT316735 Il1 Positive_regulation of Gene_expression of Il1rn 1 0.00 0.53 0.53
50 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53
51 INT214164 Binding of Mc4r and Pomc 1 0.39 1.31 0.53
52 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53
53 INT119745 NEUROD1 Regulation of Gene_expression of BHLHE22 1 0.11 0.26 0.53
54 INT24869 GAL Regulation of Localization of Gh 1 0.19 0.4 0.51
55 INT95042 Binding of NEUROD1 and Olr1246 1 0.02 0.23 0.51
56 INT89186 Agrp Negative_regulation of Mc4r 1 0.40 0 0.51
57 INT49150 GAL Regulation of Localization of Gnrhr 1 0.00 0.09 0.51
58 INT130335 Binding of Mc4r and Nr3c2 1 0.06 1.87 0.5
59 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
60 INT257720 Bdnf Regulation of Vgf 1 0.19 0.64 0.49
61 INT130726 Negative_regulation of Binding of IL1B and Il1rn 1 0.01 0.6 0.48
62 INT257719 Ngf Regulation of Vgf 1 0.22 0.64 0.48
63 INT130723 Binding of IL1A and Il1rn 1 0.01 0.59 0.47
64 INT130724 Negative_regulation of Binding of IL1A and Il1rn 1 0.01 0.59 0.47
65 INT280614 Il6 Regulation of Transcription of Irs1 1 0.26 0.4 0.46
66 INT335594 Myo5a Regulation of Hmmr 1 0.00 0.39 0.45
67 INT348784 Ins1 Positive_regulation of Irs1 1 0.09 3.47 0.44
68 INT296237 Anxa1 Regulation of Gene_expression of Trpm8 1 0.03 0.57 0.43
69 INT296231 Anxa1 Regulation of Gene_expression of Trpa1 1 0.03 0.57 0.43
70 INT230437 Binding of PDX1 and HRCT1 1 0.04 2.45 0.43
71 INT171185 Binding of NEUROD1 and ACOT1 1 0.01 0.37 0.42
72 INT61345 Iapp Regulation of GAL 2 0.08 0.35 0.41
73 INT296235 Trpm8 Regulation of Positive_regulation of Anxa1 1 0.03 0.62 0.41
74 INT59742 Glp1r Positive_regulation of Gene_expression of Npy 1 0.27 0.32 0.41
75 INT59740 Glp1r Positive_regulation of Localization of Npy 1 0.25 0.33 0.41
76 INT59739 Glp1r Positive_regulation of Transcription of Npy 1 0.25 0.32 0.41
77 INT241679 EIF2AK3 Positive_regulation of Atf4 1 0.06 0.46 0.4
78 INT222180 Binding of HNF1B and TFAM 1 0.01 1.48 0.4
79 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
80 INT171898 Il1rn Regulation of Gene_expression of Il1 1 0.02 0.92 0.4
81 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
82 INT152164 Binding of GALR3 and GAL 2 0.31 0.88 0.39
83 INT237415 Il1rn Regulation of Il10 1 0.03 0.96 0.39
84 INT237417 Il1rn Regulation of Il4 1 0.02 0.96 0.39
85 INT24755 GAL Regulation of Regulation of Calca 1 0.16 0 0.38
86 INT55427 Grpr Positive_regulation of Localization of Glp1r 1 0.02 0 0.38
87 INT70010 Binding of Neurod1 and Insrr 1 0.01 0.11 0.37
88 INT214142 Agrp Positive_regulation of Mc4r 1 0.39 0.23 0.37
89 INT214145 Binding of Agrp and Mc4r 1 0.40 0.18 0.37
90 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
91 INT230499 Gene_expression of Il1rn Negative_regulation of Gene_expression of Icam1 1 0.01 0.85 0.36
92 INT230438 Binding of PDX1 and HAUS7 1 0.02 2.29 0.35
93 INT242363 Binding of Il1a and Il1rn 1 0.05 0.19 0.35
94 INT213484 Binding of Lep and Pik3c3 1 0.01 0 0.35
95 INT322208 HRCT1 Positive_regulation of PDX1 1 0.01 1.31 0.34
96 INT335455 Negative_regulation of Binding of PDX1 and hb 1 0.02 1.3 0.33
97 INT55426 Sct Positive_regulation of Localization of Glp1r 1 0.49 0 0.33
98 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
99 INT303993 Lep Positive_regulation of Gene_expression of IL2 1 0.15 0.24 0.33
100 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
101 INT213485 Lep Positive_regulation of Localization of Grin2a 1 0.19 0 0.31
102 INT55429 Binding of Gip and Glp1r 1 0.39 0 0.31
103 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
104 INT168948 Binding of CCK and CCKAR 1 0.23 0 0.3
105 INT335446 Binding of PDX1 and COPD 1 0.02 1.99 0.3
106 INT75042 Binding of MC2R and MC4R 1 0.00 0.18 0.3
107 INT226989 Lias Regulation of Gene_expression of Lep 1 0.10 0.91 0.3
108 INT55425 Gip Positive_regulation of Localization of Glp1r 1 0.44 0 0.3
109 INT303983 Lep Positive_regulation of CXCL10 1 0.06 0.31 0.29
110 INT118239 Binding of CCKAR and CYP2B6 1 0.32 0.19 0.29
111 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29
112 INT303998 Lep Positive_regulation of Localization of IL1RAPL1 1 0.04 0.31 0.29
113 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29
114 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
115 INT287747 Anxa1 Positive_regulation of Lpar1 1 0.04 0 0.29
116 INT137023 Gene_expression of SMAD2 Negative_regulation of Gene_expression of Acta2 1 0.00 0.43 0.29
117 INT60449 GAL Positive_regulation of Gnrhr 1 0.00 0 0.29
118 INT287748 Positive_regulation of Anxa1 Positive_regulation of Lpar1 1 0.04 0 0.29
119 INT246841 Binding of Irs1 and Ppp1r13b 5 0.16 0.94 0.28
120 INT303984 Lep Positive_regulation of Gene_expression of IL8 1 0.06 0.85 0.28
121 INT185806 Binding of PDX1 and MMP7 1 0.02 0.84 0.28
122 INT118852 Positive_regulation of GNA14 Positive_regulation of CAMK2G 1 0.01 0.09 0.27
123 INT298277 Pou4f1 Negative_regulation of Gene_expression of Neurod1 1 0.58 0.48 0.27
124 INT256001 Ang Negative_regulation of Il1rn 1 0.11 0.25 0.27
125 INT118846 GNA14 Positive_regulation of CAMK2G 1 0.01 0.09 0.27
126 INT167488 Binding of NEUROD1 and GGNBP2 1 0.08 0 0.27
127 INT255996 H7 Negative_regulation of Il1rn 1 0.01 0.25 0.27
128 INT100531 Cck Positive_regulation of Lep 1 0.70 0.15 0.26
129 INT83220 Gucy1a2 Positive_regulation of Positive_regulation of Glp1r 1 0.02 0 0.26
130 INT68298 Binding of Neurod1 and Abt1 1 0.24 0 0.26
131 INT162502 NEUROD1 Regulation of CYP1A1 2 0.07 0.09 0.25
132 INT162501 NEUROD1 Regulation of CYP1A2 2 0.22 0.09 0.25
133 INT317251 Npy Positive_regulation of Gpr119 1 0.32 0 0.25
134 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
135 INT130691 CA2 Positive_regulation of EIF2AK3 1 0.16 0.59 0.24
136 INT335447 PDX1 Regulation of Gene_expression of COPD 1 0.02 1.03 0.24
137 INT337892 Positive_regulation of Mc4r Positive_regulation of Gene_expression of Nr2f2 1 0.34 0 0.23
138 INT303988 Lep Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.55 0.23
139 INT260835 NRP2 Positive_regulation of Eif2ak3 1 0.00 0.73 0.23
140 INT332481 ANXA1 Regulation of SGPP2 1 0.45 1.01 0.22
141 INT224908 Binding of SLC6A7 and GAL 1 0.17 0.37 0.22
142 INT102937 Gnrh1 Positive_regulation of Gene_expression of Lep 1 0.50 0 0.22
143 INT224904 Binding of GALR2 and GAL 1 0.16 0.37 0.22
144 INT110653 Lep Regulation of Localization of Cck 1 0.06 0.22 0.22
145 INT20310 Binding of Hnf1a and Positive_regulation of Transcription of Cyp2e1 1 0.02 0 0.21
146 INT132680 HNF1A Positive_regulation of Gene_expression of UGT1A6 1 0.30 0.08 0.21
147 INT257728 Binding of Pbx2 and Vgf 1 0.42 0.18 0.21
148 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
149 INT207185 Binding of Bmi1 and Lep 1 0.01 1.7 0.21
150 INT132679 HNF1A Regulation of Gene_expression of UGT1A6 1 0.16 0.08 0.21
151 INT354519 Cacna1c Regulation of Mri1 1 0.00 1.15 0.21
152 INT203527 Pou4f1 Negative_regulation of Neurod1 1 0.32 0.54 0.2
153 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2
154 INT304001 Lep Negative_regulation of ICAM3 1 0.07 0.35 0.2
155 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
156 INT18966 TNF Positive_regulation of NEUROD1 1 0.53 0.83 0.2
157 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2
158 INT303979 Lep Positive_regulation of ITGB2 1 0.11 0.35 0.2
159 INT256576 Lep Regulation of Localization of Ins1 1 0.57 2.08 0.2
160 INT303991 Lep Negative_regulation of SELL 1 0.04 0.35 0.2
161 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19
162 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19
163 INT303964 Lep Positive_regulation of Icam1 1 0.24 0.35 0.19
164 INT244054 Prkaca Regulation of Neurod1 1 0.02 0.06 0.19
165 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19
166 INT280621 Il6 Negative_regulation of Transcription of Irs1 1 0.25 0.4 0.19
167 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
168 INT303981 Lep Positive_regulation of Localization of CXCL1 1 0.02 0.34 0.18
169 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
170 INT210862 Binding of POMC and Mc4r 1 0.34 0.42 0.17
171 INT226988 Lias Positive_regulation of Localization of Lep 1 0.08 0.3 0.17
172 INT173938 Il1rn Negative_regulation of Il1 1 0.00 0.18 0.17
173 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16
174 INT333447 Binding of SMAD2 and RXRA 1 0.04 0 0.16
175 INT255736 Mapk8 Positive_regulation of Phosphorylation of Irs1 1 0.14 2.31 0.16
176 INT303980 Lep Positive_regulation of Transcription of IL2 1 0.10 0.24 0.16
177 INT329002 POMC Positive_regulation of Mc4r 1 0.13 0 0.16
178 INT59744 Glp1r Regulation of Localization of Ins1 1 0.07 0.14 0.16
179 INT246843 Positive_regulation of Binding of Irs1 and Ppp1r13b 1 0.18 0.28 0.16
180 INT111284 AGRP Negative_regulation of MC4R 1 0.46 0 0.14
181 INT296233 Binding of Anxa1 and Trpa1 1 0.03 0.78 0.14
182 INT332485 SGPP2 Regulation of ANXA1 1 0.27 0.69 0.13
183 INT111283 Regulation of Binding of AGRP and MC4R 1 0.48 0 0.12
184 INT214141 Binding of Lep and Lepr 1 0.32 0.82 0.12
185 INT111285 Positive_regulation of Binding of AGRP and MC4R 1 0.50 0 0.12
186 INT10731 NEUROD1 Regulation of CD4 1 0.42 1.3 0.12
187 INT10732 NEUROD1 Regulation of CD9 1 0.49 1.29 0.12
188 INT317162 Binding of Bdnf and Htt 1 0.51 0.2 0.12
189 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
190 INT240806 Binding of Glp1r and Arc 1 0.19 0.53 0.11
191 INT294742 Lep Positive_regulation of Localization of Icam1 1 0.15 0.48 0.11
192 INT163817 Lep Positive_regulation of Phosphorylation of Akt1 1 0.33 0.31 0.11
193 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11
194 INT303989 Lep Positive_regulation of IL12A 1 0.05 0.39 0.11
195 INT240805 Positive_regulation of Binding of Glp1r and Arc 1 0.24 0.53 0.11
196 INT214152 Binding of Mc4r and Msx1 1 0.03 0.24 0.11
197 INT246844 Binding of Irs1 and Myl7 1 0.05 0.43 0.11
198 INT321983 Glp1r Negative_regulation of Localization of Gcg 1 0.09 1.36 0.11
199 INT319315 Binding of Ap2a2 and Htt 1 0.28 0.64 0.11
200 INT303966 Lep Regulation of Il1 2 0.09 0.41 0.1

Single Events

The table below shows the top 100 pain related interactions that have been reported for insulin secretion. They are ordered first by their pain relevance and then by number of times they were reported in insulin secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4868 Gene_expression of GAL 75 0.78 22.23 29.02
2 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
3 INT18400 Localization of Glp1r 97 0.80 11.96 24.32
4 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
5 INT64442 Regulation of Mc4r 6 0.62 5.22 19.09
6 INT33542 Gene_expression of Il1rn 41 0.76 32.47 18.08
7 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97
8 INT4866 Positive_regulation of GAL 32 0.67 13.02 16.16
9 INT64447 Transcription of Mc4r 14 0.61 6.08 15.29
10 INT49606 Gene_expression of Il1rn 30 0.66 15.78 14.82
11 INT109031 Positive_regulation of Eif2ak3 44 0.69 21.11 14.72
12 INT7587 Localization of GAL 27 0.78 4.79 14.29
13 INT109034 Gene_expression of Eif2ak3 37 0.77 17.11 14.19
14 INT64445 Gene_expression of Mc4r 17 0.78 5.06 12.91
15 INT73641 Regulation of Lep 45 0.62 26.2 12.59
16 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23
17 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
18 INT85017 Positive_regulation of Mc4r 13 0.67 7.56 10.86
19 INT89184 Gene_expression of Mc4r 55 0.77 23.85 10.65
20 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
21 INT62544 Gene_expression of Anxa1 21 0.47 13.56 9.71
22 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
23 INT149138 Binding of PDX1 27 0.37 32.62 9.33
24 INT150678 Positive_regulation of Gene_expression of Eif2ak3 17 0.69 6.64 8.99
25 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89
26 INT82082 Localization of Lep 63 0.81 26.41 8.56
27 INT4867 Positive_regulation of Gene_expression of GAL 17 0.70 6.65 8.28
28 INT64449 Negative_regulation of Gene_expression of Mc4r 7 0.58 2 7.86
29 INT64370 Gene_expression of Neurod1 22 0.75 5.19 7.1
30 INT47944 Positive_regulation of Localization of Glp1r 23 0.70 0.16 6.79
31 INT69980 Negative_regulation of Il1rn 11 0.33 7.75 6.7
32 INT47942 Positive_regulation of Glp1r 38 0.70 15.94 6.47
33 INT64444 Negative_regulation of Mc4r 9 0.58 5.12 6.44
34 INT50328 Positive_regulation of Vgf 8 0.70 13.98 6.37
35 INT126395 Positive_regulation of Gene_expression of Il1rn 11 0.41 7.66 6.25
36 INT6097 Negative_regulation of NEUROD1 30 0.57 9.71 6.24
37 INT72110 Gene_expression of Glp1r 48 0.78 22.46 6.17
38 INT36757 Gene_expression of Eif2ak3 4 0.74 0.15 6.06
39 INT6098 Binding of NEUROD1 17 0.47 3.4 5.99
40 INT107441 Positive_regulation of Gene_expression of Il1rn 7 0.46 3.24 5.95
41 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
42 INT114993 Binding of Myo5a 15 0.30 11.46 5.48
43 INT114180 Negative_regulation of Il1rn 22 0.57 11.06 5.44
44 INT91338 Binding of Lep 31 0.48 26.86 5.39
45 INT49149 Transcription of GAL 9 0.67 2.18 5.39
46 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36
47 INT23725 Gene_expression of CCKAR 14 0.55 0.14 5.3
48 INT102935 Regulation of Lep 31 0.60 18.47 5.24
49 INT23638 Negative_regulation of GAL 17 0.42 5.68 5.04
50 INT105609 Negative_regulation of Mc4r 10 0.58 10.4 5.04
51 INT58750 Binding of GAL 16 0.47 5.48 4.92
52 INT114183 Positive_regulation of Il1rn 17 0.55 11.31 4.83
53 INT64446 Negative_regulation of Transcription of Mc4r 4 0.43 1.01 4.8
54 INT137336 Phosphorylation of Eif2ak3 14 0.79 4.72 4.78
55 INT96504 Negative_regulation of SLC18A2 5 0.36 2.07 4.62
56 INT64441 Regulation of Transcription of Mc4r 3 0.27 2.93 4.62
57 INT97391 Binding of Lep 18 0.48 8.97 4.47
58 INT76683 Positive_regulation of Il1rn 9 0.51 9.3 4.41
59 INT37379 Regulation of Localization of Glp1r 10 0.62 0.16 4.32
60 INT230796 Phosphorylation of Irs1 70 0.81 31.73 4.13
61 INT163581 Localization of Lep 27 0.79 18.99 4.08
62 INT5602 Positive_regulation of Eif2ak3 9 0.66 0 4.04
63 INT14439 Regulation of GAL 12 0.61 2.25 4.02
64 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
65 INT85497 Gene_expression of Anxa1 6 0.77 4.7 3.68
66 INT20011 Regulation of NEUROD1 10 0.44 3.83 3.53
67 INT23728 Negative_regulation of CCKAR 6 0.42 0.48 3.53
68 INT257727 Transcription of Vgf 1 0.72 7.38 3.52
69 INT83646 Binding of Il1rn 12 0.37 4.41 3.51
70 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
71 INT40232 Transcription of Il1rn 8 0.53 9.6 3.37
72 INT133214 Regulation of PDX1 9 0.34 10.26 3.36
73 INT106341 Phosphorylation of Irs1 18 0.72 14.7 3.3
74 INT62547 Positive_regulation of Gene_expression of Anxa1 5 0.42 4.52 3.27
75 INT50326 Gene_expression of Vgf 11 0.78 4.41 3.2
76 INT48042 Positive_regulation of Anxa1 5 0.50 3.64 3.19
77 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16
78 INT61347 Positive_regulation of Localization of GAL 4 0.49 1.06 3.15
79 INT171888 Binding of Il1rn 13 0.38 5.53 3.13
80 INT66599 Gene_expression of MC4R 16 0.78 12.37 3.12
81 INT210838 Positive_regulation of Mc4r 17 0.53 6.79 3.06
82 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
83 INT134798 Gene_expression of ANXA1 15 0.75 13.94 2.99
84 INT18399 Regulation of Glp1r 11 0.53 3.78 2.97
85 INT39856 Binding of Neurod1 8 0.47 1.44 2.88
86 INT132773 Negative_regulation of Acvr2b 3 0.41 1.55 2.87
87 INT85947 Regulation of Cckar 2 0.36 2.4 2.86
88 INT106340 Positive_regulation of Phosphorylation of Irs1 8 0.53 7.03 2.85
89 INT171058 Negative_regulation of PDX1 5 0.32 9.31 2.72
90 INT130028 Positive_regulation of Gene_expression of Mc4r 2 0.45 0.41 2.7
91 INT48651 Regulation of Gene_expression of GAL 7 0.61 2.95 2.63
92 INT50325 Regulation of Vgf 2 0.62 4.4 2.58
93 INT203819 Binding of Eif2ak3 9 0.37 5.94 2.57
94 INT165726 Positive_regulation of Anxa1 7 0.29 3.16 2.57
95 INT15695 Positive_regulation of EIF2AK3 12 0.67 7.01 2.56
96 INT23534 Regulation of CCKAR 8 0.32 0.17 2.56
97 INT48654 Negative_regulation of Gene_expression of GAL 5 0.42 2.14 2.56
98 INT76679 Positive_regulation of Transcription of Il1rn 1 0.37 9.13 2.55
99 INT240953 Positive_regulation of Ffar1 14 0.67 4.81 2.53
100 INT62064 Negative_regulation of Gene_expression of Il1rn 6 0.32 4.81 2.53
101 INT127113 Positive_regulation of Phosphorylation of Smad2 1 0.68 2.38 2.51
102 INT69981 Positive_regulation of Negative_regulation of Il1rn 2 0.09 3.28 2.48
103 INT40505 Positive_regulation of CCKAR 3 0.40 0 2.42
104 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
105 INT210833 Regulation of Mc4r 4 0.30 1.57 2.38
106 INT115654 Localization of Glp1r 11 0.75 3.79 2.34
107 INT72109 Negative_regulation of Localization of Glp1r 8 0.59 0.8 2.3
108 INT194504 Gene_expression of Smad2 27 0.65 7.45 2.25
109 INT131928 Localization of Il1rn 3 0.74 2.22 2.24
110 INT19286 Negative_regulation of Cacna1c 11 0.46 5.12 2.22
111 INT36758 Positive_regulation of Gene_expression of Eif2ak3 1 0.48 0 2.21
112 INT166838 Positive_regulation of ANXA1 4 0.64 4.88 2.16
113 INT82048 Positive_regulation of Neurod1 7 0.49 2.39 2.13
114 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
115 INT123588 Localization of Vgf 3 0.81 2.35 2.07
116 INT83392 Transcription of Lep 6 0.54 5.07 2.04
117 INT59737 Negative_regulation of Glp1r 15 0.43 6.94 2.01
118 INT237322 Gene_expression of Irs1 52 0.77 21.07 2
119 INT112368 Positive_regulation of Cacna1c 8 0.46 2.94 1.97
120 INT36755 Positive_regulation of Localization of Eif2ak3 1 0.48 0 1.97
121 INT36756 Localization of Eif2ak3 1 0.71 0 1.96
122 INT150675 Regulation of Gene_expression of Eif2ak3 3 0.40 1.11 1.93
123 INT133269 Positive_regulation of PDX1 10 0.54 9.77 1.9
124 INT171059 Localization of PDX1 8 0.56 6.7 1.9
125 INT13999 Positive_regulation of Positive_regulation of NEUROD1 5 0.67 4.07 1.86
126 INT173931 Regulation of Gene_expression of Il1rn 3 0.60 2.68 1.84
127 INT30373 Localization of CCKAR 5 0.68 0.17 1.79
128 INT89639 Phosphorylation of CAMK2G 5 0.48 0.66 1.78
129 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
130 INT36759 Regulation of Gene_expression of Eif2ak3 1 0.59 0 1.74
131 INT101875 Binding of MC4R 6 0.47 0.19 1.73
132 INT85498 Positive_regulation of Gene_expression of Anxa1 3 0.50 2.12 1.7
133 INT113897 Positive_regulation of Transcription of Mc4r 1 0.45 0 1.7
134 INT230799 Positive_regulation of Phosphorylation of Irs1 28 0.69 11.17 1.63
135 INT109033 Positive_regulation of Positive_regulation of Eif2ak3 2 0.45 2.36 1.59
136 INT178264 Positive_regulation of Gene_expression of Mc4r 10 0.43 3.52 1.57
137 INT123076 Gene_expression of Cacna1c 7 0.37 1.91 1.56
138 INT65602 Negative_regulation of Neurod1 7 0.42 2.52 1.55
139 INT317226 Gene_expression of Gpr119 1 0.53 0.74 1.54
140 INT127115 Regulation of Phosphorylation of Smad2 1 0.60 1.74 1.53
141 INT85499 Regulation of Anxa1 1 0.27 1.88 1.52
142 INT15048 Regulation of Cacna1c 4 0.29 3.26 1.47
143 INT150677 Negative_regulation of Eif2ak3 9 0.58 6.24 1.46
144 INT64371 Positive_regulation of Gene_expression of Neurod1 4 0.64 1.56 1.45
145 INT255251 Negative_regulation of Smad2 12 0.32 5.69 1.44
146 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44
147 INT65452 Negative_regulation of Cacna1c 8 0.09 0.8 1.44
148 INT54775 Binding of Cckar 1 0.34 0 1.43
149 INT27356 Localization of NEUROD1 8 0.78 3.44 1.39
150 INT311241 Transcription of Myo5a 1 0.50 1.61 1.37
151 INT215864 Localization of Eif2ak3 5 0.75 3.26 1.36
152 INT18337 Transcription of Eif2ak3 3 0.68 0 1.36
153 INT168954 Binding of CCKAR 1 0.28 0 1.36
154 INT132915 Phosphorylation of GAL 1 0.61 0 1.36
155 INT129619 Phosphorylation of Smad2 34 0.61 11.6 1.34
156 INT23727 Positive_regulation of Gene_expression of CCKAR 4 0.31 0 1.34
157 INT244284 Binding of SLC18A2 1 0.23 1.87 1.34
158 INT240842 Positive_regulation of Gene_expression of Irs1 31 0.69 12 1.31
159 INT77752 Binding of Cacna1c 3 0.22 0.22 1.31
160 INT183065 Positive_regulation of Gene_expression of PDX1 7 0.54 6.58 1.29
161 INT120970 Negative_regulation of Irs1 12 0.37 8.65 1.28
162 INT18971 Positive_regulation of Gene_expression of NEUROD1 8 0.67 1.91 1.23
163 INT127900 Phosphorylation of EIF2AK3 14 0.80 7.99 1.22
164 INT101022 Regulation of Il1rn 5 0.44 2.15 1.21
165 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19
166 INT213465 Transcription of Lep 4 0.68 2.11 1.15
167 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12
168 INT97369 Regulation of Gene_expression of NEUROD1 1 0.26 0.25 1.12
169 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
170 INT125147 Binding of Mc4r 10 0.41 3.55 1.08
171 INT66452 Positive_regulation of Cacna1c 6 0.19 2.56 1.08
172 INT108997 Localization of Htt 28 0.77 3.76 1.07
173 INT137338 Regulation of Eif2ak3 8 0.45 5.5 1.07
174 INT331098 Negative_regulation of Positive_regulation of Mc4r 1 0.32 1.08 1.07
175 INT75846 Positive_regulation of MC4R 7 0.70 5.73 1.05
176 INT71233 Negative_regulation of Anxa1 1 0.07 0.15 1.05
177 INT94210 Regulation of Neurod1 2 0.33 0.07 1.04
178 INT145864 Gene_expression of Irs1 5 0.71 3.34 1.01
179 INT228871 Negative_regulation of Gene_expression of Anxa1 2 0.03 1.92 1.01
180 INT240800 Positive_regulation of Gene_expression of Glp1r 1 0.44 2.01 1.01
181 INT122151 Localization of Anxa1 1 0.75 0.53 1
182 INT132574 Positive_regulation of SLC18A2 1 0.12 0.25 0.99
183 INT78935 Localization of Cacna1c 3 0.48 1.25 0.97
184 INT292529 Phosphorylation of Il1rn 1 0.09 1 0.97
185 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
186 INT246720 Gene_expression of Glp1r 9 0.63 6.53 0.96
187 INT145851 Negative_regulation of Positive_regulation of Il1rn 1 0.08 0.7 0.95
188 INT173929 Regulation of Il1rn 5 0.26 3.02 0.93
189 INT192785 Regulation of Myo5a 4 0.05 9.05 0.93
190 INT145852 Negative_regulation of Negative_regulation of Il1rn 1 0.08 0.69 0.93
191 INT113736 Negative_regulation of Positive_regulation of Mc4r 1 0.08 1.11 0.93
192 INT218696 Negative_regulation of Phosphorylation of Smad2 3 0.42 4.36 0.92
193 INT326601 Gene_expression of SLC18A2 2 0.42 1.31 0.92
194 INT51906 Negative_regulation of Gene_expression of NEUROD1 4 0.57 1.56 0.91
195 INT55422 Binding of Glp1r 7 0.48 3.35 0.9
196 INT255990 Localization of Il1rn 6 0.73 1.74 0.9
197 INT171889 Negative_regulation of Gene_expression of Il1rn 3 0.08 2.31 0.9
198 INT123589 Positive_regulation of Positive_regulation of Vgf 7 0.50 2.92 0.88
199 INT240368 Positive_regulation of Localization of Eif2ak3 1 0.34 0.66 0.87
200 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
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