GO:0030101

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Name natural killer cell activation
Categary Process
Go Slim No
Go Link GO:0030101
Unique Molecular Interactions 199
Total Molecular Interactions 259
Total Single Events 2397
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for natural killer cell activation. They are ordered first by their pain relevance and then by number of times they were reported for natural killer cell activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76
2 INT329956 Binding of IL2 and IL23R 1 0.33 4.58 1.21
3 INT88193 Binding of IL2 and IL4 1 0.13 1.7 1.2
4 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06
5 INT21415 POMC Positive_regulation of Gene_expression of IL2 1 0.00 0.27 1
6 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
7 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
8 INT134782 Il2rb Regulation of Gene_expression of Crp 1 0.00 1.16 0.92
9 INT161306 POMC Negative_regulation of Transcription of IL2 1 0.24 0.27 0.85
10 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
11 INT161305 NFKB1 Positive_regulation of IL2 1 0.25 0.25 0.83
12 INT12883 Binding of IL2 and POMC 1 0.01 0 0.81
13 INT8411 IL2 Regulation of Gene_expression of Vip 1 0.00 0.27 0.8
14 INT266769 IL2 Positive_regulation of Localization of IL4 1 0.00 1.03 0.72
15 INT209029 Il12b Positive_regulation of Elf1 1 0.24 0.37 0.72
16 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
17 INT209030 Il12b Positive_regulation of Cxcl1 1 0.16 0.37 0.72
18 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72
19 INT266765 IL2 Positive_regulation of Localization of IL10 1 0.01 1.03 0.72
20 INT209032 Il12b Positive_regulation of Csf2 1 0.08 0.37 0.72
21 INT27034 HERPUD1 Regulation of Gene_expression of IL2 1 0.38 0 0.71
22 INT13238 POMC Regulation of Gene_expression of IL2 1 0.09 0.26 0.59
23 INT202018 Binding of KIR3DS1 and MRAP 1 0.13 0.59 0.59
24 INT74656 YY1 Positive_regulation of Localization of IL2 1 0.07 0.09 0.58
25 INT39210 TF Positive_regulation of Gene_expression of IL2 1 0.17 0.07 0.57
26 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57
27 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
28 INT144598 Hrh2 Positive_regulation of IL2 1 0.01 0.08 0.56
29 INT328936 Binding of HLA-B and KIR3DS1 1 0.25 0.7 0.48
30 INT337326 PIK3CD Positive_regulation of Localization of ITPR3 1 0.02 0 0.43
31 INT337325 PIK3CD Positive_regulation of Phosphorylation of IL2RG 1 0.00 0 0.43
32 INT337324 PIK3CD Positive_regulation of Gene_expression of ITPR3 1 0.02 0 0.43
33 INT95206 Binding of CSF2 and IL2 1 0.40 1.81 0.4
34 INT292891 IL2 Regulation of IL5 1 0.02 0.25 0.39
35 INT237778 Il12b Positive_regulation of Gene_expression of Eae1 1 0.01 1.51 0.39
36 INT292889 IL2 Regulation of IL12A 1 0.01 0.25 0.39
37 INT292886 IL2 Regulation of IL8 1 0.03 0.25 0.39
38 INT172148 Binding of IL2 and TNF 2 0.05 0.67 0.37
39 INT217028 Adp Negative_regulation of Il12b 1 0.00 0 0.37
40 INT172135 Binding of IL2 and IL6 1 0.01 0.57 0.37
41 INT27036 HERPUD1 Positive_regulation of Gene_expression of IL2 1 0.31 0 0.37
42 INT68119 Binding of IL2 and Oprd1 1 0.02 0 0.37
43 INT27032 ASNA1 Regulation of Gene_expression of IL2 1 0.03 0 0.36
44 INT320699 Gene_expression of Ptger2 Negative_regulation of Gene_expression of IL2 1 0.00 1.1 0.35
45 INT27033 HERPUD1 Regulation of Gene_expression of CD2 1 0.34 0 0.34
46 INT27031 HERPUD1 Regulation of CD2 1 0.34 0 0.34
47 INT267589 IL2 Positive_regulation of Gene_expression of IL12A 1 0.01 0.69 0.34
48 INT39208 ALOX5 Regulation of Gene_expression of IL2 1 0.04 0.06 0.34
49 INT285565 Positive_regulation of Zeb1 Negative_regulation of IL2 1 0.02 0.62 0.33
50 INT285566 F8 Negative_regulation of IL2 1 0.00 0.62 0.33
51 INT285563 Zeb1 Negative_regulation of IL2 1 0.01 0.62 0.33
52 INT303993 Lep Positive_regulation of Gene_expression of IL2 1 0.15 0.24 0.33
53 INT194621 TNF Positive_regulation of Gene_expression of Klrk1 1 0.05 0.5 0.32
54 INT194614 Il15 Positive_regulation of Gene_expression of Klrk1 1 0.04 0.5 0.32
55 INT34727 TNF Positive_regulation of Gene_expression of IL2 1 0.56 0.81 0.31
56 INT94076 ARSA Negative_regulation of Gene_expression of IL2 1 0.13 0.09 0.3
57 INT94072 ARSA Regulation of Gene_expression of IL2 1 0.07 0.09 0.29
58 INT62753 IL2 Regulation of POMC 1 0.27 0 0.28
59 INT19513 Prl Positive_regulation of IL2 1 0.41 0.8 0.27
60 INT68118 Binding of IL2 and OPRD1 1 0.35 0 0.26
61 INT237380 Binding of Cdkn2d and Il12b 1 0.01 0.45 0.26
62 INT189145 MTNR1B Positive_regulation of Gene_expression of IL2 1 0.02 0.3 0.26
63 INT351007 Binding of IL2 and IL2RA 1 0.33 1.33 0.26
64 INT354393 NCR1 Regulation of Localization of UNK 1 0.17 0 0.25
65 INT307011 MT1JP Regulation of IL2 1 0.01 0 0.24
66 INT63196 INS Positive_regulation of IL2 1 0.10 0.3 0.23
67 INT63197 POMC Positive_regulation of IL2 1 0.16 0.3 0.23
68 INT164517 CABIN1 Positive_regulation of Transcription of IL2 1 0.13 0.35 0.22
69 INT63200 PTH Positive_regulation of IL2 1 0.24 0.29 0.22
70 INT318303 Negative_regulation of Myoz1 Negative_regulation of Transcription of IL2 1 0.00 0.75 0.21
71 INT141043 ZNF404 Negative_regulation of Transcription of IL2 1 0.01 0 0.21
72 INT299787 Binding of IL2 and ISG20 1 0.04 0.82 0.21
73 INT39209 TMSB4XP5 Positive_regulation of Gene_expression of IL2 1 0.07 0 0.21
74 INT34903 CALM1 Negative_regulation of Gene_expression of IL2 1 0.18 0 0.2
75 INT226528 BTPs Negative_regulation of Gene_expression of IL2 1 0.04 0.22 0.19
76 INT292625 IL2 Positive_regulation of Gene_expression of IL9 1 0.11 0.29 0.19
77 INT99013 Binding of Itgb2 and Selp 1 0.16 1.36 0.18
78 INT298196 EGFR Positive_regulation of PIK3CD 1 0.04 0.65 0.18
79 INT99011 Regulation of Binding of Itgb2 and Selp 1 0.19 1.37 0.18
80 INT355882 TNF Positive_regulation of Gene_expression of Il12b 1 0.03 0.21 0.18
81 INT107425 Binding of ST3GAL4 and IFNK 1 0.08 1.12 0.17
82 INT252326 Binding of Cx3cl1 and Klrk1 1 0.01 0.23 0.16
83 INT353037 IL4 Positive_regulation of IL2 1 0.02 0.99 0.16
84 INT303980 Lep Positive_regulation of Transcription of IL2 1 0.10 0.24 0.16
85 INT353038 IL4 Positive_regulation of Localization of IL2 1 0.02 0.99 0.16
86 INT273714 Positive_regulation of Binding of Icam1 and Itgb2 1 0.17 1.46 0.15
87 INT233386 Binding of Il12a and Il12b 1 0.01 0.48 0.15
88 INT273717 Binding of Icam1 and Itgb2 1 0.17 1.45 0.15
89 INT49608 IL2 Positive_regulation of Alpk1 1 0.01 1.47 0.14
90 INT237774 Il12b Positive_regulation of Eae1 1 0.01 0.58 0.13
91 INT173406 Binding of ITGAL and Itgb2 1 0.02 0.41 0.13
92 INT335460 FPR1 Positive_regulation of PIK3CD 1 0.17 0 0.13
93 INT289958 Binding of IL2 and IL2RB 1 0.02 0.59 0.12
94 INT39207 LBR Positive_regulation of Gene_expression of IL2 1 0.23 0 0.11
95 INT352030 Binding of NR3C1 and IL2 1 0.15 0.5 0.11
96 INT286969 IL2 Regulation of Gene_expression of FOXP3 1 0.04 1.05 0.1
97 INT49283 Binding of IGLL1 and IFNK 1 0.02 0.9 0.1
98 INT232653 Binding of CD2 and MLL 1 0.02 0.27 0.1
99 INT232652 Binding of CD2 and ITGAL 1 0.03 0.28 0.09
100 INT202020 Binding of TYROBP and NCR1 1 0.01 0.36 0.09
101 INT333095 Localization of IL2 Negative_regulation of Negative_regulation of CD8A 1 0.10 0.8 0.09
102 INT328435 PIK3CD Positive_regulation of Gene_expression of VEGFA 1 0.23 0.64 0.09
103 INT194730 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL2 1 0.06 0 0.09
104 INT33809 IL2 Regulation of Regulation of LIPE 1 0.23 0.09 0.09
105 INT333099 Localization of IL2 Negative_regulation of Negative_regulation of CD4 1 0.14 0.8 0.09
106 INT337536 Binding of Klrk1 and COPD 1 0.03 3.09 0.09
107 INT33806 IL2 Regulation of ADRB3 1 0.28 0.08 0.09
108 INT173408 GPER Regulation of Itgb2 1 0.01 0.23 0.08
109 INT159852 Gene_expression of IL2 Regulation of Gene_expression of ACTN1 1 0.03 0.16 0.07
110 INT278059 XRCC1 Positive_regulation of Gene_expression of IL2 1 0.01 1.06 0.07
111 INT159854 Gene_expression of IL2 Regulation of Gene_expression of CDC42EP5 1 0.01 0.16 0.07
112 INT348168 Thbs1 Positive_regulation of PIK3CD 1 0.00 0.65 0.07
113 INT33807 IL2 Negative_regulation of Negative_regulation of LIPE 1 0.16 0.06 0.07
114 INT333092 Binding of CD4 and IL2 1 0.01 0.17 0.07
115 INT159853 Gene_expression of IL2 Regulation of Gene_expression of RHO 1 0.17 0.16 0.07
116 INT333098 Binding of CD8A and IL2 1 0.01 0.17 0.07
117 INT159851 Positive_regulation of RHOA Positive_regulation of Gene_expression of IL2 1 0.15 0.15 0.06
118 INT286966 IL2 Positive_regulation of Binding of STAT3 1 0.04 0.5 0.06
119 INT186375 TNF Negative_regulation of Gene_expression of Il12b 1 0.03 0.78 0.06
120 INT194678 IL2 Positive_regulation of Positive_regulation of MAPK1 1 0.05 0 0.06
121 INT302164 PTEN Regulation of PIK3CD 1 0.16 1.13 0.06
122 INT237151 Binding of Klrk1 and Ulbp1 1 0.05 1.02 0.05
123 INT194664 Negative_regulation of MAPK1 Negative_regulation of IL2 1 0.06 0 0.05
124 INT110960 Binding of CD2 and GYPA 1 0.01 0.19 0.05
125 INT354392 TNFSF12 Regulation of NCR1 1 0.10 0.09 0.05
126 INT60089 IL2 Regulation of IFNA2 1 0.25 0.09 0.05
127 INT351010 ISG20 Positive_regulation of Transcription of IL2 1 0.31 0.46 0.05
128 INT336388 Binding of IL2 and ALPK1 1 0.06 0.73 0.05
129 INT351009 IL2RG Positive_regulation of Transcription of IL2 1 0.27 0.44 0.05
130 INT351008 IL2RB Positive_regulation of Gene_expression of IL2 1 0.18 0.42 0.05
131 INT328438 PRB4 Negative_regulation of PIK3CD 1 0.06 0.29 0.05
132 INT237149 Binding of H60a and Klrk1 1 0.24 1.01 0.05
133 INT237150 Binding of Klrk1 and Rae1 1 0.04 1.14 0.05
134 INT268674 IL2 Positive_regulation of XRCC1 1 0.08 0.75 0.05
135 INT194694 MAPK1 Negative_regulation of Gene_expression of IL2 1 0.04 0 0.04
136 INT331172 Binding of IFNA1 and IL2 1 0.00 0.46 0.04
137 INT354390 TNFSF12 Regulation of Gene_expression of NCR1 1 0.13 0 0.04
138 INT35172 IL2 Positive_regulation of Gene_expression of IFNG 1 0.01 0.27 0.04
139 INT176326 IL2 Positive_regulation of Gene_expression of MUC1 1 0.08 0.71 0.04
140 INT286962 IL2 Regulation of Gene_expression of CD4 1 0.01 0.45 0.04
141 INT270206 Hdl1 Positive_regulation of Gene_expression of IL2 1 0.01 0.35 0.03
142 INT332286 PIK3CD Positive_regulation of MTOR 1 0.14 0.73 0.03
143 INT328436 PRB4 Negative_regulation of Gene_expression of PIK3CD 1 0.07 0.24 0.03
144 INT328430 PRB4 Regulation of Positive_regulation of PIK3CD 1 0.06 0.4 0.03
145 INT332284 IRS1 Regulation of PIK3CD 1 0.15 0.72 0.03
146 INT321402 Binding of NPHS1 and PIK3CD 1 0.02 0.73 0.03
147 INT60088 IFNA2 Positive_regulation of IL2 1 0.12 0.07 0.03
148 INT211191 CD28 Positive_regulation of Gene_expression of IL2 1 0.15 0.15 0.03
149 INT273719 Binding of Itgb2 and Trav6-3 1 0.07 0.47 0.03
150 INT332288 Positive_regulation of IRS1 Regulation of PIK3CD 1 0.07 0.73 0.03
151 INT235493 SFTPA1 Positive_regulation of Gene_expression of IL2 1 0.04 0 0.03
152 INT104864 IL2 Positive_regulation of NXT1 1 0.08 0 0
153 INT233387 Binding of SPINK1 and Il12b 1 0.04 0.33 0
154 INT130222 IL2 Positive_regulation of Il2rb 1 0.00 0 0
155 INT322849 Binding of PIK3CD and PDCD10 1 0.16 0 0
156 INT210707 Binding of IFNA2 and IL2 1 0.06 0.91 0
157 INT340515 HIVEP1 Regulation of IL2 1 0.01 0.32 0
158 INT328431 PIK3CD Negative_regulation of Gene_expression of VEGFA 1 0.22 0.29 0
159 INT237146 Binding of H60a and Rae1 1 0.07 0 0
160 INT235491 SFTPA1 Regulation of Gene_expression of IL2 1 0.02 0.23 0
161 INT322844 Binding of KDR and PIK3CD 1 0.04 0 0
162 INT320712 Binding of NRAS and PIK3CD 1 0.21 1.66 0
163 INT192956 Binding of CD2 and KIT 1 0.03 0.62 0
164 INT294521 Binding of IL2 and p53 1 0.40 0.1 0
165 INT111768 IL2 Positive_regulation of Localization of CRH 1 0.02 0 0
166 INT235492 SFTPA1 Positive_regulation of Localization of IL2 1 0.04 0 0
167 INT202599 Binding of IL2 and PTPN5 1 0.03 0.12 0
168 INT272775 IL2 Positive_regulation of Gene_expression of IGHG3 1 0.01 0.16 0
169 INT321788 IL2 Negative_regulation of Localization of IFN1@ 1 0.23 0.09 0
170 INT202600 IL2 Regulation of HIVEP1 1 0.01 0.5 0
171 INT270145 TNF Positive_regulation of IL2 1 0.01 0.53 0
172 INT328427 PIK3CD Negative_regulation of Phosphorylation of AKT1 1 0.09 0.29 0
173 INT322848 VEGFA Positive_regulation of PIK3CD 1 0.09 0 0
174 INT273720 Binding of Cd28 and Itgb2 1 0.10 0 0
175 INT322843 Positive_regulation of PIK3CD Positive_regulation of Positive_regulation of RHOA 1 0.03 0 0
176 INT320715 NRAS Positive_regulation of PIK3CD 1 0.27 1.66 0
177 INT181216 IL2 Positive_regulation of Gpi1 1 0.00 0.15 0
178 INT340516 CD4 Regulation of IL2 1 0.04 0.32 0
179 INT237148 Negative_regulation of Binding of Klrk1 and Rae1 1 0.05 0.13 0
180 INT293362 CSH1 Negative_regulation of Gene_expression of IL2 1 0.01 0.12 0
181 INT235495 PLAT Positive_regulation of Gene_expression of IL2 1 0.05 0 0
182 INT354404 Binding of IL18 and NCR1 1 0.22 0 0
183 INT104865 IL2 Positive_regulation of TH1L 1 0.38 0 0
184 INT104863 IL2 Positive_regulation of ZAK 1 0.19 0 0
185 INT337537 Binding of MICA and Positive_regulation of Klrk1 1 0.07 0.68 0
186 INT294522 Binding of IL2 and MDM2 1 0.40 0.2 0
187 INT294525 Binding of IL2 and PDB1 1 0.40 0.1 0
188 INT283461 Binding of IL2 and SLC4A2 1 0.01 0.98 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for natural killer cell activation. They are ordered first by their pain relevance and then by number of times they were reported in natural killer cell activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69
2 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67
3 INT10763 Localization of IL2 157 0.80 81.11 33.21
4 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7
5 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04
6 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96
7 INT15796 Regulation of IL2 66 0.61 25.43 20.62
8 INT10000 Regulation of Gene_expression of IL2 56 0.45 15.33 16.2
9 INT51014 Transcription of IL2 42 0.71 21.56 12.7
10 INT16322 Gene_expression of Il2rb 19 0.51 15.88 12.18
11 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68
12 INT22383 Binding of IL2 59 0.48 39.06 8.56
13 INT120401 Positive_regulation of PIK3CD 33 0.45 14.89 7.37
14 INT56564 Negative_regulation of Gene_expression of Il2rb 1 0.38 0 6.97
15 INT15131 Gene_expression of CD2 20 0.75 9.47 5.01
16 INT58459 Negative_regulation of Localization of IL2 13 0.41 6.46 4.88
17 INT64653 Binding of CD2 17 0.44 6.74 4.45
18 INT56562 Positive_regulation of Gene_expression of Il2rb 6 0.45 3.17 4.34
19 INT110343 Negative_regulation of PIK3CD 22 0.40 5.84 4.2
20 INT29138 Positive_regulation of Localization of IL2 25 0.50 10.06 3.89
21 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89
22 INT144231 Gene_expression of Il12b 18 0.75 12.93 3.65
23 INT133169 Positive_regulation of Il12b 25 0.49 13 3.64
24 INT133174 Positive_regulation of Gene_expression of Il12b 29 0.15 13.04 2.92
25 INT153439 Gene_expression of KIR3DS1 3 0.66 2.77 2.92
26 INT22831 Negative_regulation of Positive_regulation of IL2 7 0.55 1.7 2.62
27 INT141367 Negative_regulation of Transcription of IL2 9 0.32 2.07 2.43
28 INT36100 Positive_regulation of Il2rb 7 0.49 4.18 2.32
29 INT20289 Regulation of Localization of IL2 7 0.26 1.23 2.24
30 INT51461 Gene_expression of Itgb2 7 0.75 5.48 2.2
31 INT92648 Positive_regulation of IL12B 7 0.20 4.55 2.19
32 INT153444 Positive_regulation of KIR3DS1 3 0.67 2.34 2.18
33 INT264967 Positive_regulation of Positive_regulation of PIK3CD 4 0.18 1.97 2.13
34 INT74156 Positive_regulation of Il12b 3 0.49 1.54 2.04
35 INT92056 Transcription of Il12b 8 0.69 4.75 1.95
36 INT133170 Negative_regulation of Il12b 12 0.05 5.32 1.86
37 INT199591 Protein_catabolism of IL2 2 0.05 1.2 1.81
38 INT97108 Phosphorylation of IL2 5 0.73 2.47 1.7
39 INT100586 Localization of Il2rb 6 0.15 3.18 1.64
40 INT88746 Positive_regulation of Transcription of IL2 7 0.51 2.14 1.6
41 INT174230 Positive_regulation of Gene_expression of IL12B 6 0.49 3.2 1.56
42 INT243799 Gene_expression of PIK3CD 15 0.45 6.63 1.5
43 INT97142 Localization of IL12B 5 0.73 1.73 1.46
44 INT152190 Positive_regulation of Phosphorylation of IL2 1 0.23 0.2 1.41
45 INT87029 Positive_regulation of Positive_regulation of IL2 8 0.50 8.17 1.36
46 INT194611 Gene_expression of Klrk1 28 0.44 19.31 1.28
47 INT100909 Negative_regulation of Gene_expression of Itgb2 2 0.41 1.79 1.22
48 INT236329 Regulation of IL12B 3 0.02 0.78 1.2
49 INT202022 Binding of KIR3DS1 2 0.30 1.43 1.2
50 INT97261 Negative_regulation of Regulation of IL2 2 0.26 1.04 1.17
51 INT92055 Positive_regulation of Transcription of Il12b 4 0.49 2.77 1.16
52 INT85995 Gene_expression of NCR1 5 0.45 3.39 1.15
53 INT264969 Localization of PIK3CD 5 0.50 0.64 1.13
54 INT68018 Positive_regulation of CD2 3 0.65 0.79 1.13
55 INT233357 Localization of Il12b 7 0.16 3.4 1.12
56 INT112004 Positive_regulation of Negative_regulation of IL2 3 0.50 1.56 1.08
57 INT22830 Negative_regulation of Binding of IL2 4 0.55 4.8 1.06
58 INT144232 Negative_regulation of Gene_expression of Il12b 4 0.41 2.26 1.01
59 INT100911 Positive_regulation of Itgb2 1 0.51 1.62 0.99
60 INT233349 Regulation of Il12b 5 0.05 3.71 0.98
61 INT133173 Regulation of Negative_regulation of Il12b 2 0.04 0.52 0.97
62 INT36437 Regulation of CD2 3 0.30 0 0.91
63 INT178803 Gene_expression of Itgb2 10 0.44 5.13 0.87
64 INT92649 Negative_regulation of Gene_expression of IL12B 3 0.03 2.23 0.86
65 INT36439 Regulation of Gene_expression of CD2 3 0.22 0.33 0.86
66 INT19279 Negative_regulation of Negative_regulation of IL2 3 0.43 1.62 0.79
67 INT186283 Negative_regulation of Gene_expression of Il12b 2 0.13 7.92 0.74
68 INT100910 Regulation of Positive_regulation of Itgb2 1 0.20 0.53 0.72
69 INT51459 Positive_regulation of Gene_expression of Itgb2 2 0.37 1.92 0.7
70 INT186136 Negative_regulation of Binding of CD2 2 0.29 2.06 0.68
71 INT74155 Transcription of Il12b 3 0.60 1.45 0.66
72 INT156544 Regulation of Il12b 2 0.44 1.29 0.66
73 INT61623 Regulation of Positive_regulation of IL2 1 0.21 0.33 0.65
74 INT264964 Positive_regulation of Localization of PIK3CD 1 0.13 0.05 0.62
75 INT186277 Binding of Il12b 4 0.20 2.15 0.55
76 INT100588 Positive_regulation of Localization of Il2rb 1 0.09 0.52 0.53
77 INT330393 Positive_regulation of Gene_expression of Il12b 2 0.49 1.24 0.48
78 INT51462 Regulation of Gene_expression of Itgb2 2 0.34 0.79 0.47
79 INT28694 Negative_regulation of CD2 2 0.37 1.21 0.45
80 INT154565 Regulation of Positive_regulation of PIK3CD 2 0.09 1.59 0.45
81 INT143548 Binding of Itgb2 1 0.35 0 0.44
82 INT233355 Positive_regulation of Localization of Il12b 2 0.11 0.99 0.43
83 INT185318 Negative_regulation of Transcription of Il12b 2 0.06 1.03 0.43
84 INT337345 Regulation of Gene_expression of PIK3CD 1 0.20 0 0.43
85 INT118202 Negative_regulation of Itgb2 1 0.41 1.05 0.42
86 INT100587 Negative_regulation of Localization of Il2rb 1 0.11 0.23 0.41
87 INT337344 Negative_regulation of Negative_regulation of PIK3CD 1 0.19 0 0.4
88 INT219212 Positive_regulation of Gene_expression of CD2 1 0.33 0 0.4
89 INT233356 Negative_regulation of Positive_regulation of Il12b 3 0.13 0.85 0.38
90 INT36440 Negative_regulation of Gene_expression of CD2 1 0.35 0 0.38
91 INT233350 Regulation of Gene_expression of Il12b 1 0.06 3.03 0.37
92 INT92652 Negative_regulation of Positive_regulation of IL12B 1 0.03 0.99 0.36
93 INT237144 Binding of Klrk1 3 0.18 3.44 0.34
94 INT49286 Binding of IFNK 2 0.25 2.48 0.34
95 INT348183 Binding of IL12B 1 0.46 0.97 0.33
96 INT99005 Positive_regulation of Itgb2 8 0.39 6.36 0.27
97 INT98996 Regulation of Itgb2 2 0.25 2.09 0.27
98 INT219210 Regulation of Binding of CD2 1 0.30 0 0.27
99 INT329823 Negative_regulation of Il12b 1 0.42 0.57 0.27
100 INT298430 Positive_regulation of Protein_catabolism of IL2 1 0.03 0.85 0.26
101 INT293350 Regulation of Binding of IL2 2 0.22 0.87 0.23
102 INT60017 Regulation of Il2rb 1 0.01 0.71 0.23
103 INT294675 Localization of Il12b 2 0.78 1.15 0.19
104 INT34479 Gene_expression of IFNK 1 0.75 0.88 0.18
105 INT354425 Regulation of NCR1 1 0.23 0 0.18
106 INT119167 Positive_regulation of Transcription of Il12b 1 0.09 0.77 0.17
107 INT302261 Regulation of PIK3CD 7 0.29 5.34 0.15
108 INT115522 Regulation of Itgb2 3 0.19 0.5 0.15
109 INT344816 Regulation of Gene_expression of Itgb2 1 0.07 0.56 0.15
110 INT243793 Phosphorylation of PIK3CD 5 0.42 1.74 0.13
111 INT354412 Transcription of NCR1 1 0.40 0.46 0.13
112 INT202034 Regulation of Positive_regulation of KIR3DS1 1 0.23 0.41 0.13
113 INT237761 Phosphorylation of Il12b 1 0.09 0.49 0.11
114 INT273704 Binding of Itgb2 3 0.20 2.59 0.1
115 INT60016 Negative_regulation of Il2rb 2 0.02 2.26 0.08
116 INT273698 Positive_regulation of Positive_regulation of Itgb2 1 0.39 0.22 0.08
117 INT328448 Negative_regulation of Gene_expression of PIK3CD 1 0.21 0.84 0.08
118 INT233354 Positive_regulation of Positive_regulation of Il12b 1 0.06 2.91 0.07
119 INT186310 Positive_regulation of Binding of Il12b 1 0.15 1.07 0.07
120 INT57480 Regulation of Negative_regulation of IL2 1 0.45 0.37 0.07
121 INT49285 Regulation of IFNK 1 0.18 0.81 0.06
122 INT97135 Positive_regulation of Localization of IL12B 2 0.49 0.92 0.05
123 INT244650 Positive_regulation of Binding of IL2 1 0.20 1.39 0.05
124 INT337525 Positive_regulation of Gene_expression of Klrk1 1 0.17 2.32 0.05
125 INT254584 Transcription of Il2rb 1 0.01 0 0.05
126 INT276472 Positive_regulation of NCR1 2 0.29 0.49 0.04
127 INT337524 Regulation of Klrk1 1 0.17 2.05 0.03
128 INT235499 Regulation of Regulation of IL2 1 0.27 0 0.03
129 INT305355 Transcription of IL12B 1 0.52 0.46 0.03
130 INT337565 Regulation of Transcription of IL2 1 0.45 0.51 0.03
131 INT320732 Binding of PIK3CD 3 0.20 1.66 0
132 INT311855 Regulation of Negative_regulation of PIK3CD 1 0.04 0.28 0
133 INT237142 Regulation of Gene_expression of Klrk1 1 0.26 0.12 0
134 INT337527 Positive_regulation of Klrk1 1 0.17 1.64 0
135 INT279322 Regulation of Gene_expression of Il2rb 1 0.14 0.3 0
136 INT97143 Regulation of Localization of IL12B 1 0.08 0 0
137 INT279323 Binding of Il2rb 1 0.09 1.86 0
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