GO:0030131

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Name clathrin adaptor complex
Categary Component
Go Slim No
Go Link GO:0030131
Unique Molecular Interactions 40
Total Molecular Interactions 57
Total Single Events 216
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for clathrin adaptor complex. They are ordered first by their pain relevance and then by number of times they were reported for clathrin adaptor complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT33314 Binding of Ap1m1 and Ap1m2 1 0.07 0.97 5.42
2 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9
3 INT90929 Binding of Ap1m1 and Insrr 1 0.01 0.19 1.6
4 INT13755 Binding of Oprd1 and Ap2m1 1 0.20 0 1.32
5 INT69562 Positive_regulation of AP2M1 Positive_regulation of Regulation of Adrb3 1 0.01 0.19 1.24
6 INT58140 Binding of AP2M1 and Oprm1 1 0.01 0.4 1.23
7 INT56205 Binding of Ap1m2 and Insrr 1 0.00 0.07 0.96
8 INT146240 Binding of AP1B1 and Mrgprc 1 0.08 0.82 0.85
9 INT122833 AP1B1 Regulation of Gene_expression of Fos 1 0.16 0 0.83
10 INT6408 Binding of NFKBIL1 and Ap1m2 1 0.00 0 0.8
11 INT43321 Oprd1 Regulation of Ap2m1 1 0.20 0 0.63
12 INT72227 Binding of BTRC and AP1M2 1 0.00 0 0.49
13 INT122832 AP1B1 Negative_regulation of Gene_expression of FLII 1 0.01 0 0.47
14 INT29906 Binding of Scn4a and Ap2m1 1 0.09 0 0.43
15 INT72226 Binding of AP1M2 and EMID1 1 0.00 0 0.26
16 INT72228 Negative_regulation of Binding of OPRD1 and AP1M2 1 0.04 0 0.25
17 INT72224 Binding of OPRD1 and AP1M2 1 0.03 0 0.25
18 INT111908 Binding of HSPD1 and AP4B1 1 0.03 0.48 0.25
19 INT287763 Binding of Gria2 and Ap3m1 1 0.02 0.33 0.21
20 INT333510 Positive_regulation of STON1 Positive_regulation of GPI 1 0.10 0.38 0.19
21 INT107634 Slc25a1 Regulation of AP4B1 1 0.00 0.1 0.13
22 INT107622 KNG1 Regulation of AP4B1 1 0.19 0.1 0.13
23 INT333511 STON1 Positive_regulation of GYPE 1 0.10 0.49 0.12
24 INT333509 STON1 Positive_regulation of GPI 1 0.04 0.49 0.12
25 INT319315 Binding of Ap2a2 and Htt 1 0.28 0.64 0.11
26 INT250804 Binding of CCL4L1 and AP5M1 1 0.01 1.48 0.08
27 INT250801 Binding of AP5M1 and MAPKAP1 1 0.00 1.48 0.08
28 INT305737 Binding of Sort1 and Gga2 1 0.19 0.11 0.06
29 INT250802 Binding of IL6 and AP5M1 1 0.01 1.47 0.05
30 INT220630 Binding of Bace1 and Gga1 3 0.25 0.07 0
31 INT220631 Gene_expression of Gga1 Positive_regulation of Bace1 2 0.24 0 0
32 INT220628 Gene_expression of Gga1 Positive_regulation of App 2 0.22 0 0
33 INT333772 Positive_regulation of Casp3 Positive_regulation of Gga3 1 0.05 0.5 0
34 INT297000 Binding of AP2A1 and AP1B1 1 0.00 0.21 0
35 INT333771 Casp3 Positive_regulation of Gga3 1 0.05 0.5 0
36 INT297057 Binding of AP1B1 and Sag 1 0.00 0 0
37 INT297003 Binding of AP1B1 and AP2B1 1 0.00 0.21 0
38 INT297002 Binding of AP1B1 and CLINT1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for clathrin adaptor complex. They are ordered first by their pain relevance and then by number of times they were reported in clathrin adaptor complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT24780 Binding of Ap1m1 20 0.29 4.75 25.05
2 INT29812 Binding of Ap1m2 14 0.33 3.66 14.55
3 INT13754 Binding of Ap2m1 7 0.36 0.96 5.64
4 INT33308 Gene_expression of Ap1m2 5 0.15 0.44 5.08
5 INT57125 Gene_expression of AP1B1 8 0.18 3.8 4.91
6 INT5994 Positive_regulation of Ap1m2 3 0.18 0.07 4.68
7 INT33313 Gene_expression of Ap1m1 4 0.41 0.44 4.04
8 INT42823 Negative_regulation of Ap1m1 2 0.14 0.3 3.85
9 INT54375 Negative_regulation of Ap1m2 2 0.03 0.22 2.97
10 INT57123 Localization of AP1B1 5 0.24 1.29 2.91
11 INT162957 Positive_regulation of STON1 5 0.35 4.83 2.77
12 INT13626 Positive_regulation of Ap2m1 5 0.49 0.94 2.47
13 INT72237 Binding of AP1M2 3 0.25 0 1.94
14 INT57122 Positive_regulation of Localization of AP1B1 3 0.16 0.39 1.93
15 INT7781 Regulation of Ap2m1 3 0.60 0.26 1.9
16 INT351284 Regulation of Localization of AP1M2 1 0.04 0.85 1.9
17 INT351285 Localization of AP1M2 1 0.07 0.79 1.89
18 INT33306 Negative_regulation of Binding of Ap1m1 2 0.26 0.75 1.88
19 INT57124 Positive_regulation of AP1B1 4 0.19 0.94 1.74
20 INT98283 Negative_regulation of STON1 5 0.48 2.26 1.61
21 INT120543 Gene_expression of AP4B1 4 0.58 1.75 1.44
22 INT12806 Positive_regulation of AP2M1 2 0.67 0.19 1.35
23 INT120544 Positive_regulation of Gene_expression of AP4B1 1 0.52 1.22 1.3
24 INT107633 Positive_regulation of AP4B1 4 0.52 1.67 1.28
25 INT13750 Transcription of Ap2m1 1 0.57 0 1.2
26 INT59408 Regulation of Ap1m2 1 0.05 0 1.2
27 INT60762 Gene_expression of Ap3m1 1 0.01 0.25 1.15
28 INT33656 Gene_expression of Ap2m1 2 0.04 0.14 1.1
29 INT141360 Negative_regulation of AP1B1 2 0.21 0 1.06
30 INT29905 Localization of Ap2m1 2 0.66 0 1.05
31 INT33310 Localization of Ap1m1 1 0.48 0.24 1.05
32 INT33309 Localization of Ap1m2 1 0.18 0.24 1.05
33 INT154312 Gene_expression of STON1 3 0.54 3.17 1
34 INT33311 Transcription of Ap1m2 1 0.15 0.17 0.98
35 INT33312 Transcription of Ap1m1 1 0.41 0.17 0.98
36 INT35108 Binding of AP4B1 2 0.32 0.67 0.91
37 INT151682 Regulation of STON1 3 0.24 1.98 0.88
38 INT20709 Positive_regulation of Positive_regulation of Ap2m1 1 0.49 0 0.77
39 INT146238 Positive_regulation of Gene_expression of AP1B1 1 0.11 0.72 0.76
40 INT59696 Gene_expression of AP2M1 1 0.65 0.23 0.7
41 INT146237 Negative_regulation of Gene_expression of AP1B1 1 0.10 0.58 0.62
42 INT56204 Negative_regulation of Binding of Ap1m2 1 0.05 0.16 0.57
43 INT101155 Binding of AP1B1 2 0.36 0.13 0.56
44 INT220566 Negative_regulation of Gga3 6 0.35 5.98 0.5
45 INT113532 Binding of AP2M1 1 0.47 0.19 0.47
46 INT57120 Regulation of AP1B1 1 0.02 0.37 0.43
47 INT29903 Negative_regulation of Ap2m1 1 0.48 0 0.43
48 INT57121 Negative_regulation of Positive_regulation of AP1B1 1 0.03 0.3 0.42
49 INT333515 Positive_regulation of Positive_regulation of STON1 1 0.13 0.38 0.4
50 INT147077 Localization of AP4B1 1 0.10 0.07 0.39
51 INT220589 Protein_catabolism of Gga3 2 0.39 2 0.28
52 INT209719 Phosphorylation of AP1B1 1 0.10 0.07 0.28
53 INT5397 Negative_regulation of AP2B1 1 0.08 0.4 0.28
54 INT72236 Negative_regulation of AP1M2 1 0.19 0 0.25
55 INT69997 Positive_regulation of Ap2a2 1 0.01 0.15 0.25
56 INT69995 Localization of Ap2a2 1 0.02 0.14 0.23
57 INT6373 Positive_regulation of AP5M1 2 0.01 1.92 0.22
58 INT69996 Gene_expression of Ap2a2 1 0.01 0.14 0.18
59 INT250817 Binding of AP5M1 2 0.01 2.72 0.15
60 INT201016 Positive_regulation of AP2B1 2 0.36 1.01 0.09
61 INT220595 Gene_expression of Gga3 2 0.40 1.32 0.07
62 INT250811 Regulation of AP5M1 1 0.01 2.45 0.07
63 INT220572 Positive_regulation of Negative_regulation of Gga3 2 0.30 0.16 0.03
64 INT262693 Regulation of Negative_regulation of Gga3 1 0.24 0.75 0.03
65 INT220610 Gene_expression of Gga1 3 0.36 0.06 0
66 INT220613 Positive_regulation of Gene_expression of Gga1 2 0.32 0 0
67 INT297043 Regulation of AP2B1 1 0.19 1.22 0
68 INT250812 Gene_expression of AP5M1 1 0.02 0.76 0
69 INT178210 Localization of STON1 1 0.07 1.26 0
70 INT297036 Regulation of Gene_expression of AP2B1 1 0.32 0.54 0
71 INT272124 Localization of AP5M1 1 0.01 1.66 0
72 INT220583 Positive_regulation of Gga3 1 0.30 0.1 0
73 INT297032 Gene_expression of AP2B1 1 0.48 0.54 0
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