GO:0030157

From wiki-pain
Jump to: navigation, search
Name pancreatic juice secretion
Categary Process
Go Slim No
Go Link GO:0030157
Unique Molecular Interactions 113
Total Molecular Interactions 140
Total Single Events 1302
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for pancreatic juice secretion. They are ordered first by their pain relevance and then by number of times they were reported for pancreatic juice secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT138961 Dbi Positive_regulation of Chkb 1 0.00 3.05 3.99
2 INT138959 Dbi Positive_regulation of Penk 1 0.01 3.05 3.99
3 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61
4 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
5 INT138962 Dbi Positive_regulation of Pomc 1 0.00 1.53 2
6 INT138960 Dbi Positive_regulation of Avp 1 0.02 1.53 2
7 INT138958 Dbi Positive_regulation of Positive_regulation of Avp 1 0.02 1.53 2
8 INT140013 Avp Positive_regulation of Gene_expression of Dbi 1 0.07 0.85 1.52
9 INT140012 Avp Negative_regulation of Dbi 1 0.06 0.8 1.44
10 INT219686 Binding of CEL and COPD 1 0.12 11.35 1.26
11 INT76199 CASP1 Positive_regulation of CEL 1 0.06 0.32 1.14
12 INT41093 Binding of Dbi and Nil 1 0.00 0 0.93
13 INT161769 Cck Regulation of Cckar 1 0.27 0.53 0.92
14 INT55204 Prl Positive_regulation of Localization of Dbi 1 0.02 0 0.91
15 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82
16 INT99578 Binding of CEL and Kit 1 0.04 1.07 0.81
17 INT87646 Dbi Regulation of Olfr1507 1 0.00 0.69 0.72
18 INT95148 CEL Regulation of IL1B 1 0.24 0.88 0.7
19 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67
20 INT2401 SCT Positive_regulation of SGCA 1 0.00 0 0.62
21 INT26648 Binding of CEL and HP 1 0.04 0 0.58
22 INT98815 Binding of Crhr2 and Ucn 3 0.32 0.5 0.56
23 INT32479 Gh1 Negative_regulation of Dbi 1 0.01 0 0.51
24 INT160444 Tpsab1 Positive_regulation of Gene_expression of CEL 1 0.48 0.96 0.48
25 INT34982 Trh Regulation of Dbi 1 0.12 0 0.47
26 INT34984 Negative_regulation of Trh Regulation of Dbi 1 0.19 0 0.47
27 INT34983 Gene_expression of Dbi Positive_regulation of Localization of Trh 1 0.22 0 0.42
28 INT34981 Gene_expression of Dbi Positive_regulation of Localization of Prl 1 0.23 0 0.41
29 INT219683 Binding of CEL and GOPC 1 0.04 3.11 0.38
30 INT63970 Binding of TRPV1 and Copa 1 0.00 0 0.37
31 INT164371 Dbi Regulation of Pomc 1 0.19 0.17 0.35
32 INT88904 Binding of SCT and Hcrt 1 0.07 0 0.31
33 INT88903 Regulation of Binding of SCT and Hcrt 1 0.06 0 0.31
34 INT168948 Binding of CCK and CCKAR 1 0.23 0 0.3
35 INT260433 Dbi Positive_regulation of Cd8a 1 0.00 0.13 0.3
36 INT35858 PRSS1 Regulation of Positive_regulation of SCT 1 0.17 0.18 0.3
37 INT17162 Binding of CEL and Lhb 1 0.06 0.38 0.3
38 INT139778 Binding of AQP1 and GBE1 1 0.00 0.22 0.3
39 INT118239 Binding of CCKAR and CYP2B6 1 0.32 0.19 0.29
40 INT98816 Crhr2 Positive_regulation of Negative_regulation of Ucn 1 0.33 0.09 0.28
41 INT233785 Binding of SCT and VIPR1 1 0.08 0 0.27
42 INT233784 Binding of GCG and SCT 1 0.06 0 0.27
43 INT233781 Binding of PTH1R and SCT 1 0.18 0 0.27
44 INT233786 Binding of CALCR and SCT 1 0.05 0 0.27
45 INT233780 Binding of ADCYAP1 and SCT 1 0.16 0 0.27
46 INT233782 Binding of PTHLH and SCT 1 0.06 0 0.27
47 INT233783 Binding of SCT and VIPR2 1 0.13 0 0.27
48 INT82194 Dbi Regulation of Oprd1 1 0.12 0.07 0.26
49 INT60360 SCT Regulation of NTS 1 0.13 0 0.24
50 INT43532 Dbi Negative_regulation of Localization of LH 1 0.15 0.75 0.23
51 INT60361 SCT Regulation of CCK 1 0.19 0 0.23
52 INT58305 AQP1 Regulation of Localization of TNF 1 0.10 0.16 0.22
53 INT58303 AQP1 Regulation of Gene_expression of IL1B 1 0.10 0.16 0.22
54 INT35966 SCT Regulation of Localization of LIPF 1 0.32 0.24 0.22
55 INT35472 Dbi Regulation of Gnrh1 1 0.06 0.17 0.22
56 INT35967 SCT Positive_regulation of Localization of LIPF 1 0.33 0.24 0.22
57 INT106993 CEL Positive_regulation of NR1I2 1 0.39 0.39 0.22
58 INT35468 Dbi Regulation of Prl 1 0.05 0.17 0.22
59 INT143394 Ucn Regulation of Crh 1 0.44 0.19 0.2
60 INT46285 SCT Positive_regulation of PRSS1 1 0.16 0.1 0.19
61 INT35471 Dbi Negative_regulation of Localization of Gnrh1 1 0.05 0.14 0.19
62 INT46286 SCT Positive_regulation of CTRC 1 0.24 0.1 0.19
63 INT348059 Dbi Negative_regulation of Binding of Mpo 1 0.08 0.43 0.19
64 INT49057 Positive_regulation of CEL Positive_regulation of Localization of LTC4S 1 0.41 0.28 0.18
65 INT94355 NOVA2 Positive_regulation of Dbi 1 0.00 0.15 0.18
66 INT42521 Pomc Regulation of Dbi 1 0.06 0 0.17
67 INT32665 Pomc Negative_regulation of Dbi 1 0.06 0 0.17
68 INT5520 Negative_regulation of Dbi Negative_regulation of Gene_expression of Crh 1 0.21 0.44 0.16
69 INT5517 Negative_regulation of Dbi Negative_regulation of Crh 1 0.27 0.44 0.16
70 INT355410 Ins1 Regulation of Gene_expression of Dbi 1 0.07 0.57 0.16
71 INT35860 PRSS1 Regulation of Localization of SCT 1 0.10 0.08 0.16
72 INT231838 Pcdh8 Regulation of Cel 1 0.00 0.39 0.15
73 INT85816 Binding of CEL and TTR 1 0.39 0.77 0.14
74 INT231846 Pcdh8 Negative_regulation of Positive_regulation of Cel 1 0.00 0.91 0.14
75 INT355408 Ins1 Regulation of Dbi 1 0.07 0.58 0.14
76 INT92671 Binding of CEL and HLA-B 1 0.38 0.19 0.1
77 INT246535 Binding of Cel and Mag 1 0.01 7.26 0.1
78 INT43530 Dbi Negative_regulation of LH 1 0.18 0.3 0.1
79 INT5519 Dbi Negative_regulation of Crh 1 0.31 0.28 0.1
80 INT32030 Binding of CEL and ERLEC1 1 0.08 0.42 0.1
81 INT43529 Dbi Negative_regulation of Gene_expression of LH 1 0.13 0.3 0.1
82 INT139250 CCKAR Positive_regulation of Localization of POMC 1 0.35 0.61 0.09
83 INT41574 POMC Regulation of CCKAR 1 0.00 0 0.09
84 INT94353 Crh Negative_regulation of Positive_regulation of Dbi 1 0.03 0.14 0.08
85 INT205033 Ucn Positive_regulation of Crhr2 1 0.22 0.15 0.08
86 INT94354 Crh Negative_regulation of Dbi 1 0.03 0.14 0.08
87 INT43528 Dbi Regulation of Localization of LH 1 0.09 0.21 0.07
88 INT45623 Binding of ALB and SCT 1 0.10 0.12 0.06
89 INT222544 Binding of Ucn and Crh 1 0.02 0 0.05
90 INT231834 Trip12 Positive_regulation of Positive_regulation of Cel 1 0.00 0.75 0.05
91 INT133047 TNF Positive_regulation of Gene_expression of CEL 1 0.47 0.61 0.05
92 INT177350 Binding of CEL and PLA2G2A 1 0.06 0.08 0.04
93 INT222417 Ucn Positive_regulation of Localization of Pomc 1 0.01 0 0.04
94 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
95 INT222469 Binding of Ucn and Crhr2 1 0.00 0 0.03
96 INT280601 Binding of HIVEP1 and Dbi 1 0.00 1.57 0.03
97 INT177352 Binding of CEL and PTN 1 0.01 0 0.03
98 INT352625 Trp53 Regulation of CEL 1 0.00 0.71 0
99 INT304135 Binding of CEL and Positive_regulation of CASP8 1 0.00 0.52 0
100 INT262746 Binding of Dbi and RN7SL2 1 0.00 0 0
101 INT79900 NFE2L2 Positive_regulation of Gene_expression of AQP1 1 0.03 0 0
102 INT262498 Binding of Aqp1 and Cav1 1 0.03 0.56 0
103 INT44885 Binding of CEL and MET 1 0.39 0.15 0
104 INT246536 Mag Regulation of Gene_expression of Cel 1 0.01 1.28 0
105 INT169485 Dbi Regulation of Prkca 1 0.02 0.08 0
106 INT35470 Binding of Prl and Dbi 1 0.05 0.17 0
107 INT98626 Aqp1 Positive_regulation of Aqp4 1 0.52 0 0
108 INT169484 Dbi Regulation of Oprk1 1 0.01 0.07 0
109 INT285042 Dbi Regulation of Gene_expression of Rho 1 0.01 0 0
110 INT262747 Binding of CHN1 and Dbi 1 0.01 0 0
111 INT68256 Binding of GH1 and SCT 1 0.04 0.54 0
112 INT4817 Binding of CALCA and SCT 1 0.01 0 0
113 INT183740 Dbi Negative_regulation of A230066D03Rik 1 0.00 0.69 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for pancreatic juice secretion. They are ordered first by their pain relevance and then by number of times they were reported in pancreatic juice secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2
2 INT5989 Positive_regulation of Dbi 79 0.49 24.38 32.56
3 INT5988 Localization of Dbi 74 0.81 17.52 24.09
4 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58
5 INT11762 Regulation of Dbi 40 0.62 7.83 14.48
6 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87
7 INT5512 Negative_regulation of Dbi 32 0.36 7.33 9.1
8 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83
9 INT30638 Positive_regulation of Gene_expression of Dbi 17 0.69 4.63 8.28
10 INT20343 Positive_regulation of Localization of Dbi 21 0.63 5.01 6.61
11 INT19779 Binding of Dbi 41 0.36 8.8 5.87
12 INT2132 Localization of SCT 29 0.81 8.39 5.43
13 INT23725 Gene_expression of CCKAR 14 0.55 0.14 5.3
14 INT23245 Positive_regulation of Gene_expression of CEL 19 0.69 14.81 4.92
15 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
16 INT18995 Binding of CEL 23 0.47 14.46 4.5
17 INT11708 Regulation of SCT 12 0.44 2.29 4.07
18 INT4464 Localization of CEL 21 0.80 8.09 3.88
19 INT27642 Regulation of Gene_expression of Dbi 10 0.44 2.55 3.66
20 INT2886 Gene_expression of SCT 13 0.78 4.55 3.57
21 INT23728 Negative_regulation of CCKAR 6 0.42 0.48 3.53
22 INT175442 Gene_expression of Cel 22 0.34 21.36 3.33
23 INT20344 Regulation of Localization of Dbi 8 0.49 1.97 3.31
24 INT53813 Positive_regulation of Cel 20 0.58 19.39 3.05
25 INT4820 Negative_regulation of SCT 7 0.43 4.06 3.01
26 INT85947 Regulation of Cckar 2 0.36 2.4 2.86
27 INT23534 Regulation of CCKAR 8 0.32 0.17 2.56
28 INT40505 Positive_regulation of CCKAR 3 0.40 0 2.42
29 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15
30 INT3179 Positive_regulation of SCT 15 0.50 4.79 1.98
31 INT2409 Binding of SCT 7 0.48 2.69 1.94
32 INT47628 Regulation of CEL 9 0.60 4.5 1.85
33 INT30373 Localization of CCKAR 5 0.68 0.17 1.79
34 INT32543 Negative_regulation of Gene_expression of Dbi 6 0.42 2.46 1.67
35 INT80162 Localization of Ucn 6 0.80 0.6 1.66
36 INT75694 Regulation of Gene_expression of CEL 9 0.60 6.08 1.53
37 INT54775 Binding of Cckar 1 0.34 0 1.43
38 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41
39 INT168954 Binding of CCKAR 1 0.28 0 1.36
40 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
41 INT23727 Positive_regulation of Gene_expression of CCKAR 4 0.31 0 1.34
42 INT11415 Negative_regulation of Cel 5 0.38 5.67 1.29
43 INT2741 Regulation of Localization of SCT 3 0.26 0.16 1.2
44 INT32541 Positive_regulation of Positive_regulation of Dbi 2 0.39 0.5 1.14
45 INT123554 Transcription of Dbi 5 0.72 1.13 1.13
46 INT166889 Positive_regulation of Gene_expression of AQP1 10 0.70 6.43 0.99
47 INT30942 Regulation of Regulation of Dbi 2 0.07 0.12 0.98
48 INT183362 Regulation of AQP1 3 0.23 1.49 0.92
49 INT2131 Positive_regulation of Localization of SCT 6 0.47 2.01 0.88
50 INT80159 Gene_expression of Ucn 3 0.67 0.47 0.82
51 INT23726 Positive_regulation of Negative_regulation of CCKAR 1 0.08 0 0.82
52 INT322101 Localization of Cel 2 0.29 1.11 0.76
53 INT23953 Gene_expression of Cckar 3 0.65 0.2 0.74
54 INT81622 Positive_regulation of Positive_regulation of CEL 4 0.49 3.94 0.73
55 INT76127 Transcription of CEL 5 0.71 2.02 0.7
56 INT175450 Positive_regulation of Gene_expression of Cel 4 0.25 2.69 0.68
57 INT108328 Negative_regulation of Gene_expression of CEL 6 0.57 2.56 0.63
58 INT5504 Negative_regulation of Negative_regulation of Dbi 2 0.25 0.43 0.63
59 INT32542 Negative_regulation of Positive_regulation of Dbi 2 0.17 0 0.63
60 INT168965 Negative_regulation of Binding of CCKAR 1 0.22 0 0.63
61 INT168966 Positive_regulation of Localization of CCKAR 1 0.29 0 0.62
62 INT25006 Negative_regulation of Gene_expression of CCKAR 1 0.30 0 0.62
63 INT183163 Positive_regulation of Positive_regulation of Cel 9 0.31 11.55 0.58
64 INT169489 Positive_regulation of Localization of CEL 1 0.45 0.34 0.58
65 INT80160 Negative_regulation of Ucn 2 0.58 0.29 0.56
66 INT231823 Negative_regulation of Positive_regulation of Cel 2 0.17 2.34 0.56
67 INT21882 Negative_regulation of Localization of Dbi 3 0.45 0.28 0.55
68 INT98814 Negative_regulation of Ucn 2 0.27 0.14 0.55
69 INT139780 Binding of AQP1 7 0.32 4.62 0.54
70 INT62101 Protein_catabolism of CCKAR 1 0.01 0 0.54
71 INT122186 Binding of Ucn 2 0.23 0.37 0.53
72 INT80163 Positive_regulation of Gene_expression of Ucn 1 0.50 0.41 0.52
73 INT39113 Negative_regulation of Cckar 2 0.41 0.28 0.5
74 INT185621 Positive_regulation of Gene_expression of SCT 4 0.14 2.14 0.49
75 INT19592 Localization of AQP1 4 0.81 1.09 0.44
76 INT327786 Negative_regulation of Gene_expression of AQP1 3 0.29 4.21 0.44
77 INT2740 Negative_regulation of Localization of SCT 3 0.42 0.42 0.44
78 INT53811 Regulation of Cel 4 0.23 2.1 0.43
79 INT123831 Regulation of Ucn 2 0.42 0 0.42
80 INT228731 Negative_regulation of Gene_expression of Cel 2 0.17 1.12 0.41
81 INT60601 Negative_regulation of Negative_regulation of CEL 1 0.41 0.34 0.4
82 INT65090 Negative_regulation of Positive_regulation of SCT 1 0.30 0 0.4
83 INT42288 Negative_regulation of Binding of Dbi 1 0.13 0 0.37
84 INT135069 Regulation of Localization of CEL 1 0.44 0 0.34
85 INT352167 Negative_regulation of Positive_regulation of CEL 1 0.04 1.07 0.31
86 INT59862 Phosphorylation of CEL 2 0.70 0.53 0.3
87 INT53814 Regulation of Positive_regulation of Cel 2 0.23 0.45 0.29
88 INT281746 Negative_regulation of Localization of CEL 1 0.03 0.6 0.29
89 INT280795 Positive_regulation of Ucn 1 0.31 0.06 0.27
90 INT63967 Negative_regulation of Copa 1 0.02 0 0.26
91 INT122676 Positive_regulation of Ucn 1 0.43 0.92 0.26
92 INT143391 Gene_expression of Ucn 1 0.67 0.2 0.26
93 INT175459 Binding of Cel 2 0.11 6.62 0.24
94 INT16158 Protein_catabolism of CEL 1 0.64 0 0.24
95 INT30371 Regulation of Localization of CCKAR 1 0.18 0.17 0.22
96 INT202425 Negative_regulation of Transcription of CEL 1 0.03 0.49 0.21
97 INT10042 Protein_catabolism of Cckar 1 0.08 0 0.18
98 INT19780 Protein_catabolism of Dbi 3 0.29 0.43 0.17
99 INT215814 Negative_regulation of Gene_expression of Aqp1 2 0.31 0.25 0.17
100 INT76880 Localization of Cckar 2 0.07 0.08 0.17
101 INT98625 Regulation of Aqp1 1 0.27 0.1 0.17
102 INT175454 Positive_regulation of Binding of Cel 1 0.15 0.92 0.14
103 INT215820 Negative_regulation of Aqp1 3 0.23 0.83 0.1
104 INT159343 Positive_regulation of Localization of AQP1 1 0.11 0 0.1
105 INT131055 Positive_regulation of Cckar 1 0.36 0 0.09
106 INT280766 Localization of Ucn 1 0.46 0 0.07
107 INT262510 Regulation of Gene_expression of Aqp1 1 0.33 1.18 0.07
108 INT257457 Positive_regulation of Positive_regulation of SCT 1 0.20 1.66 0.07
109 INT222594 Binding of Ucn 1 0.06 0 0.03
110 INT123553 Positive_regulation of Transcription of Dbi 2 0.69 0.52 0
111 INT262504 Positive_regulation of Aqp1 1 0.25 0.43 0
112 INT238790 Regulation of Gene_expression of Cel 1 0.07 1.27 0
113 INT286264 Positive_regulation of Negative_regulation of AQP1 1 0.01 0.79 0
114 INT262513 Negative_regulation of Binding of Aqp1 1 0.23 0.64 0
115 INT19781 Negative_regulation of Protein_catabolism of Dbi 1 0.18 0 0
116 INT262514 Binding of Aqp1 1 0.20 0.64 0
117 INT352610 Regulation of Regulation of CEL 1 0.00 0.55 0
118 INT97442 Positive_regulation of Binding of CEL 1 0.67 0 0
119 INT299193 Transcription of Aqp1 1 0.56 0.62 0
120 INT262511 Positive_regulation of Gene_expression of Aqp1 1 0.37 1.78 0
121 INT327782 Regulation of Gene_expression of AQP1 1 0.36 1.63 0
122 INT262512 Localization of Aqp1 1 0.40 0.7 0
123 INT280597 Positive_regulation of Negative_regulation of Dbi 1 0.03 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox