GO:0030165

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Name PDZ domain binding
Categary Function
Go Slim No
Go Link GO:0030165
Unique Molecular Interactions 833
Total Molecular Interactions 1283
Total Single Events 9983
Pain Genes Associated 114

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for PDZ domain binding. They are ordered first by their pain relevance and then by number of times they were reported for PDZ domain binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
2 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
3 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59
4 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9
5 INT354207 Igfbp7 Positive_regulation of Accn3 1 0.52 6.55 3.24
6 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
7 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
8 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
9 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
10 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
11 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 0.07 1.72 2.46
12 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
13 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
14 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38
15 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
16 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
17 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
18 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71
19 INT354210 Binding of Igfbp7 and Accn3 1 0.27 3.91 1.64
20 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
21 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
22 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
23 INT136255 Tff3 Regulation of GRIA1 1 0.00 0.18 1.24
24 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
25 INT147033 Positive_regulation of Binding of Sds and Accn3 1 0.13 0.73 1.23
26 INT147032 Binding of Sds and Accn3 1 0.09 0.73 1.22
27 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
28 INT105918 Binding of FUT1 and SLC9A3R2 1 0.00 0.14 1.2
29 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19
30 INT162419 Binding of Abpa and Cftr 1 0.04 1.66 1.19
31 INT169082 Binding of GRIA1 and MOCOS 2 0.07 1.23 1.17
32 INT287749 Dmbx1 Positive_regulation of Gene_expression of Lpar1 1 0.41 0.82 1.16
33 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
34 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
35 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07
36 INT296460 Binding of Gria2 and Myo18a 1 0.01 1.49 1.06
37 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
38 INT231391 Binding of Lpar1 and Rbm39 1 0.00 1.04 1.04
39 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 0.05 0 0.99
40 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
41 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95
42 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94
43 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
44 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93
45 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
46 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
47 INT196591 Binding of Lpar1 and Pax3 1 0.05 1.1 0.92
48 INT281082 Binding of Gria2 and Ltp 1 0.24 0.6 0.9
49 INT281089 Binding of Gria1 and Ltp 1 0.25 0.6 0.9
50 INT146495 Snta1 Positive_regulation of Adrbk1 1 0.14 0.68 0.85
51 INT42865 Binding of Adrb2 and Man2a2 1 0.23 1.03 0.85
52 INT42864 Regulation of Binding of Adrb2 and Man2a2 1 0.28 1.03 0.85
53 INT120820 Binding of ASIC3 and Dlg4 3 0.02 0.11 0.84
54 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.08 0.83
55 INT127545 Gria1 Positive_regulation of Gene_expression of Gnptab 1 0.00 0.7 0.83
56 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
57 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
58 INT155760 Binding of Nos1 and Dlg4 1 0.13 1.01 0.82
59 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
60 INT13428 Gabrd Regulation of Localization of Sstr2 1 0.31 0 0.79
61 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78
62 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
63 INT232621 Binding of Gria1 and Psd 1 0.10 0.29 0.77
64 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
65 INT152947 Dlg4 Regulation of Sgk1 1 0.09 0.18 0.76
66 INT332538 Binding of AD5 and Cxadr 1 0.08 0.98 0.76
67 INT152945 Dlg4 Regulation of Cap1 1 0.11 0.18 0.76
68 INT164996 Ins1 Regulation of Gria2 1 0.05 0.05 0.76
69 INT344974 Lpar1 Regulation of Gene_expression of Mag 1 0.25 0.98 0.76
70 INT152944 Dlg4 Regulation of Gpr88 1 0.12 0.18 0.75
71 INT144453 Binding of GPM6A and SSTR2 1 0.02 0 0.74
72 INT4915 Binding of Tac2 and Gipc1 1 0.01 0 0.74
73 INT311525 Binding of Gria1 and Ltp 1 0.00 0.1 0.73
74 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
75 INT33575 ADRB1 Positive_regulation of Localization of Ahsp 1 0.00 0.33 0.73
76 INT248244 Binding of IL8 and SDC2 1 0.02 1.57 0.72
77 INT351351 Prkcg Regulation of Lpar1 1 0.12 0.58 0.72
78 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
79 INT351350 Prkaca Regulation of Lpar1 1 0.04 0.58 0.72
80 INT190984 Binding of Scn2a1 and Gria1 1 0.03 0.08 0.71
81 INT51433 Gria1 Positive_regulation of Eif3g 1 0.03 0 0.7
82 INT104301 Adam17 Regulation of Negative_regulation of Sell 1 0.39 0.58 0.69
83 INT282141 Grm5 Regulation of Grip2 1 0.00 0.61 0.69
84 INT117217 Binding of Calca and Hcn2 1 0.25 0.17 0.68
85 INT98525 Binding of Accn2 and Accn3 1 0.01 0.38 0.68
86 INT170832 Cftr Regulation of Scnn1a 2 0.16 1.2 0.67
87 INT153289 Binding of Lpar1 and Gpr87 2 0.29 1.19 0.67
88 INT232622 Magi2 Regulation of Cysltr1 1 0.01 0.58 0.67
89 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66
90 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66
91 INT62250 Fdft1 Regulation of Adrb1 1 0.00 0 0.65
92 INT281083 Binding of Gria1 and Gipc1 1 0.01 0 0.65
93 INT168205 Binding of Dlg4 and Pik3cd 1 0.11 0.37 0.65
94 INT197240 Grik2 Regulation of Gene_expression of Gabrg1 1 0.08 0.13 0.64
95 INT197236 Grik2 Regulation of Gabrg1 1 0.08 0.13 0.64
96 INT339794 Sstr2 Positive_regulation of Gene_expression of Sstr5 1 0.08 0.25 0.64
97 INT113610 Binding of Nsf and Grip2 1 0.24 0.6 0.63
98 INT62249 Ghrh Regulation of Adrb1 1 0.00 0 0.62
99 INT108020 Binding of Adrb1 and Clec4d 1 0.00 1.19 0.61
100 INT281079 Binding of Nsf and Gria3 1 0.19 0.05 0.61
101 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
102 INT111184 Binding of GIPC1 and CHCHD8 1 0.00 0 0.59
103 INT296463 Binding of Gria1 and Pick1 1 0.16 0.32 0.59
104 INT287753 Lpar3 Positive_regulation of Gene_expression of Lpar1 1 0.46 0.39 0.58
105 INT287744 Lpar3 Positive_regulation of Positive_regulation of Lpar1 1 0.46 0.39 0.58
106 INT287752 Dmbx1 Positive_regulation of Positive_regulation of Lpar1 1 0.41 0.39 0.58
107 INT107523 Negative_regulation of Grm5 Negative_regulation of Gene_expression of Fos 1 0.37 0.09 0.58
108 INT177269 Binding of CXADR and NR1H4 1 0.04 0 0.58
109 INT303652 Binding of SST and SSTR2 1 0.26 0.46 0.57
110 INT112107 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2a 1 0.40 0.49 0.57
111 INT296456 Gria1 Negative_regulation of Rbm39 1 0.00 0.45 0.57
112 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57
113 INT296446 Binding of Gria2 and Gria4 1 0.13 0.55 0.57
114 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56
115 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56
116 INT170833 Cftr Negative_regulation of Slc10a2 1 0.47 0.31 0.56
117 INT77394 Binding of ARRB1 and GIPC1 1 0.01 0 0.56
118 INT112106 Negative_regulation of Dlg2 Negative_regulation of Grin2a 1 0.40 0.48 0.56
119 INT281087 Binding of Gria1 and Hmmr 1 0.04 0 0.55
120 INT343597 Gys1 Regulation of Transcription of Gria2 1 0.00 0 0.55
121 INT251141 Binding of Dlg4 and Grin2b 1 0.14 0.32 0.55
122 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55
123 INT312751 Phosphorylation of Gria1 Positive_regulation of GRIA1 1 0.18 0.22 0.55
124 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
125 INT251143 Binding of Grin2b and Dlg3 1 0.22 0.32 0.55
126 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54
127 INT350169 Binding of DMD and MRI1 1 0.11 3.08 0.54
128 INT251151 Binding of Grin2a and Dlg3 1 0.24 0.32 0.54
129 INT311521 Gnrhr Positive_regulation of Gene_expression of Gria1 1 0.00 0.54 0.54
130 INT311522 Gnrhr Positive_regulation of Transcription of Gria1 1 0.00 0.54 0.54
131 INT296485 Negative_regulation of Binding of Gria2 and GRIP1 1 0.05 0.3 0.54
132 INT291386 Cntf Regulation of Gene_expression of Gria2 1 0.11 0.13 0.53
133 INT155406 Binding of Adrb2 and Ngf 1 0.05 0.39 0.53
134 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
135 INT232618 Gene_expression of Grid2ip Regulation of Localization of Gria1 1 0.28 0.86 0.52
136 INT144130 Binding of Gja1 and Prkcg 1 0.48 0.5 0.52
137 INT349130 Phosphorylation of Gria1 Positive_regulation of Shisa9 1 0.00 0.49 0.52
138 INT69291 Cftr Positive_regulation of Localization of Slc4a8 1 0.04 0.38 0.51
139 INT117482 CFTR Negative_regulation of THRB 1 0.01 0.15 0.51
140 INT322809 Binding of GRIA3 and RS1 1 0.01 0.43 0.51
141 INT322811 Binding of GRIA1 and RS1 1 0.00 0.43 0.51
142 INT169083 Binding of GRIA3 and MOCOS 2 0.07 0.51 0.5
143 INT177981 Binding of RUNX1 and SLC22A4 1 0.08 1.04 0.5
144 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
145 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
146 INT296457 Camk2a Positive_regulation of Phosphorylation of Gria1 1 0.19 0.28 0.49
147 INT70930 Sstr2 Regulation of Localization of Gh1 1 0.15 0 0.49
148 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
149 INT259183 Gria1 Positive_regulation of Phosphorylation of Gria2 1 0.30 0.39 0.49
150 INT122070 Binding of USHBP1 and Trpv1 1 0.00 0.19 0.48
151 INT232619 Binding of Gria1 and Grid2ip 1 0.23 0.51 0.48
152 INT263746 Binding of Dlg4 and Neto1 1 0.27 0 0.48
153 INT273110 Bdnf Regulation of Positive_regulation of Gria1 1 0.43 0 0.47
154 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
155 INT291018 Binding of NSF and USE1 1 0.03 0.98 0.46
156 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
157 INT341623 Binding of CFTR and CTRC 1 0.35 1.22 0.46
158 INT198931 Binding of Dlg4 and Lrp8 1 0.06 0.23 0.46
159 INT123808 Sst Regulation of Localization of Sstr2 1 0.41 0.55 0.46
160 INT303651 Binding of SSTR2 and SSTR5 1 0.24 0.23 0.45
161 INT35167 Adrb2 Positive_regulation of Trh 1 0.05 0 0.45
162 INT341624 Binding of CFTR and PRSS1 1 0.39 1.01 0.45
163 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
164 INT220188 EC Positive_regulation of CADM1 1 0.00 1.72 0.44
165 INT332539 Regulation of Binding of AD5 and Cxadr 1 0.09 0.65 0.44
166 INT256042 Negative_regulation of Musk Negative_regulation of Ntrk1 1 0.08 0.48 0.44
167 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43
168 INT328184 Positive_regulation of Slc3a1 Positive_regulation of Nsf 1 0.00 0.15 0.43
169 INT328183 Slc3a1 Positive_regulation of Nsf 1 0.00 0.15 0.43
170 INT296477 Binding of Cacng2 and Dlg4 1 0.04 0.22 0.42
171 INT135426 Binding of APBB1 and Dlg4 1 0.00 0.17 0.42
172 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
173 INT86069 Positive_regulation of Gria1 Positive_regulation of Gene_expression of Fos 1 0.11 0.3 0.42
174 INT127543 Gria1 Positive_regulation of Gene_expression of Cryge 1 0.00 0.35 0.42
175 INT74713 Binding of Gria1 and Olr1868 1 0.00 0 0.42
176 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
177 INT354208 Arc Positive_regulation of Accn3 1 0.08 0.97 0.42
178 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
179 INT127546 Gria1 Positive_regulation of Gene_expression of Kcnab3 1 0.02 0.35 0.42
180 INT146274 Binding of Rasd1 and Nos1ap 1 0.33 0.18 0.41
181 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
182 INT160971 Gm2111 Positive_regulation of Grm7 1 0.01 0.16 0.41
183 INT145575 Binding of Adra2c and Hcn2 1 0.21 0.19 0.4
184 INT299181 Cysltr1 Regulation of Musk 1 0.08 1.21 0.4
185 INT223870 Regulation of Gria2 Positive_regulation of Gene_expression of Ltp 1 0.01 0 0.4
186 INT334665 Ltp Regulation of Gria2 1 0.23 0.22 0.4
187 INT145577 Regulation of Binding of Adra2c and Hcn2 1 0.25 0.19 0.4
188 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39
189 INT287751 Rbm39 Positive_regulation of Positive_regulation of Lpar1 1 0.01 0.48 0.39
190 INT287754 Lpar2 Positive_regulation of Gene_expression of Lpar1 1 0.44 0.48 0.39
191 INT146272 Binding of Nos1 and Nos1ap 1 0.28 0.2 0.39
192 INT287745 Rbm39 Positive_regulation of Gene_expression of Lpar1 1 0.01 0.48 0.39
193 INT287740 Lpar3 Regulation of Gene_expression of Lpar1 1 0.60 0.53 0.39
194 INT287743 Lpar2 Positive_regulation of Positive_regulation of Lpar1 1 0.44 0.48 0.39
195 INT153288 Binding of Lpar1 and Lpar6 2 0.31 0.78 0.36
196 INT120821 Dlg4 Positive_regulation of ASIC3 1 0.02 0 0.36
197 INT123807 Binding of Sst and Sstr2 1 0.33 0.3 0.36
198 INT130974 Slc9a3r1 Positive_regulation of ASIC3 1 0.08 0.29 0.36
199 INT322810 SLC12A1 Regulation of Binding of GRIA1 1 0.00 0.39 0.36
200 INT84602 Binding of Adrb1 and Avp 1 0.00 0 0.36

Single Events

The table below shows the top 100 pain related interactions that have been reported for PDZ domain binding. They are ordered first by their pain relevance and then by number of times they were reported in PDZ domain binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35
2 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
3 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
4 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
5 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
6 INT64918 Gene_expression of Gria2 108 0.74 29.95 29.67
7 INT56525 Gene_expression of Gria2 74 0.75 23.15 28.6
8 INT98522 Gene_expression of Accn3 68 0.78 26.95 28.6
9 INT51602 Gene_expression of Grm5 59 0.75 17.29 26.99
10 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9
11 INT101225 Positive_regulation of Gria2 62 0.64 28.1 23.93
12 INT100124 Gene_expression of Accn3 38 0.78 30.02 23.63
13 INT76249 Gene_expression of Gria1 67 0.75 15.07 22.78
14 INT78571 Positive_regulation of Grm5 35 0.69 11.81 22.45
15 INT103842 Gene_expression of Cftr 53 0.78 59.59 21.82
16 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
17 INT129987 Phosphorylation of Gria1 63 0.80 20.65 21.02
18 INT166115 Positive_regulation of Gene_expression of Lpar1 42 0.61 31 20.71
19 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
20 INT95930 Negative_regulation of Gria2 63 0.56 18.37 17.04
21 INT153913 Positive_regulation of Lpar1 31 0.70 33.5 16.14
22 INT62861 Regulation of Gria2 45 0.60 13.35 16.07
23 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
24 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25
25 INT143276 Phosphorylation of Gria2 42 0.80 16.07 15.2
26 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06
27 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
28 INT114510 Positive_regulation of Gria2 36 0.57 14.91 14.85
29 INT170 Negative_regulation of Adrb1 52 0.55 13.46 14.78
30 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41
31 INT97100 Negative_regulation of Dlg4 16 0.58 6.18 14.36
32 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
33 INT115071 Positive_regulation of Accn3 14 0.70 16.56 14.24
34 INT49538 Binding of Gria1 22 0.47 2.66 13.35
35 INT84307 Binding of Cftr 31 0.47 26.19 12.8
36 INT88789 Gene_expression of Dlg4 26 0.78 4.41 12.74
37 INT76428 Gene_expression of Sstr2 24 0.76 6.09 12.32
38 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23
39 INT111948 Positive_regulation of Gria1 23 0.61 7.55 12.03
40 INT107522 Regulation of Grm5 9 0.44 6.42 11.46
41 INT259165 Phosphorylation of Gria2 4 0.65 11.65 11.07
42 INT57069 Regulation of Gria2 28 0.44 10.11 11.06
43 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
44 INT238920 Positive_regulation of SLC9A3R2 44 0.50 27.86 10.51
45 INT13423 Localization of Sstr2 17 0.78 0.56 10.47
46 INT109578 Positive_regulation of Accn3 16 0.70 9.09 10.05
47 INT8072 Localization of Gria1 17 0.75 2.62 10.04
48 INT115614 Binding of Gria2 25 0.43 8.97 9.91
49 INT59 Regulation of Adrb1 25 0.42 8.32 9.78
50 INT119892 Gene_expression of Cftr 54 0.77 23.76 9.73
51 INT96298 Negative_regulation of Gria1 25 0.57 10.61 9.7
52 INT77282 Positive_regulation of Cftr 23 0.69 21.8 9.65
53 INT101891 Negative_regulation of Cftr 25 0.58 24.09 9.55
54 INT259169 Positive_regulation of Phosphorylation of Gria2 3 0.40 9.98 9.34
55 INT78570 Negative_regulation of Grm5 15 0.57 5.45 9.17
56 INT30247 Regulation of Adrb1 18 0.44 4.45 8.93
57 INT107657 Positive_regulation of Positive_regulation of Grm5 6 0.69 1.83 8.92
58 INT34544 Gene_expression of L1cam 43 0.77 5.3 8.89
59 INT228870 Negative_regulation of Lpar1 17 0.51 20.97 8.77
60 INT166119 Negative_regulation of Gene_expression of Lpar1 17 0.51 13.86 8.7
61 INT108643 Gene_expression of Dlg4 61 0.76 8.63 8.58
62 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
63 INT96 Binding of Adrb1 18 0.48 2.8 8.52
64 INT22481 Gene_expression of CADM1 28 0.65 30.26 8.5
65 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
66 INT117212 Gene_expression of Hcn2 13 0.78 5.83 8.19
67 INT112099 Negative_regulation of Dlg2 2 0.40 6.17 8.16
68 INT78766 Negative_regulation of Gria2 20 0.52 6.27 8.12
69 INT205203 Gene_expression of Lpar1 6 0.39 11.83 8.08
70 INT73544 Gene_expression of Grm7 34 0.64 31.28 8.04
71 INT26115 Gene_expression of Adrb1 14 0.64 5.13 7.78
72 INT23992 Positive_regulation of Adrb1 25 0.56 4.01 7.62
73 INT114509 Transcription of Gria2 10 0.58 0.75 7.27
74 INT327801 Positive_regulation of Gene_expression of Aqp2 6 0.44 7.67 7.24
75 INT57023 Negative_regulation of Gene_expression of Gria1 20 0.58 6.92 7.17
76 INT138802 Gene_expression of CFTR 36 0.70 18.8 7.02
77 INT97099 Positive_regulation of Dlg4 13 0.60 3.04 6.98
78 INT69289 Negative_regulation of Cftr 44 0.57 13.28 6.97
79 INT139149 Binding of Gria1 22 0.37 5.71 6.88
80 INT83952 Gene_expression of Cxadr 24 0.75 22.38 6.77
81 INT120298 Negative_regulation of Phosphorylation of Gria1 6 0.57 8.99 6.68
82 INT154773 Regulation of Accn3 7 0.62 7.09 6.63
83 INT88786 Binding of Dlg4 11 0.46 2.73 6.58
84 INT87775 Phosphorylation of Gja1 13 0.82 2.75 6.56
85 INT136496 Regulation of Accn3 5 0.45 3.72 6.53
86 INT112101 Gene_expression of Dlg2 9 0.73 5.06 6.5
87 INT130875 Gene_expression of ADAM17 13 0.78 15.46 6.41
88 INT205198 Positive_regulation of Lpar1 2 0.35 7.35 6.37
89 INT251134 Binding of Dlg2 6 0.31 4.26 5.99
90 INT94927 Transcription of Gria1 12 0.69 3.14 5.94
91 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
92 INT109577 Positive_regulation of Gene_expression of Accn3 9 0.67 4.77 5.76
93 INT86119 Regulation of Cftr 13 0.45 14.08 5.75
94 INT112102 Regulation of Gene_expression of Gria2 14 0.55 5.4 5.55
95 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45
96 INT57068 Regulation of Gene_expression of Gria2 12 0.36 3.76 5.44
97 INT163217 Transcription of Sstr2 5 0.67 0.62 5.42
98 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34
99 INT125996 Gene_expression of Nsf 7 0.75 1.73 5.3
100 INT135998 Localization of Gria2 18 0.72 3.14 5.15
101 INT259167 Negative_regulation of Phosphorylation of Gria2 2 0.34 5.24 5.13
102 INT151102 Positive_regulation of CFTR 22 0.61 15.27 5.12
103 INT13885 Positive_regulation of Adrb2 9 0.49 1.11 5.12
104 INT85946 Localization of Gria2 10 0.61 1.23 5.09
105 INT107655 Positive_regulation of Gene_expression of Grm5 6 0.67 5.09 5.06
106 INT140799 Positive_regulation of Gene_expression of Accn3 6 0.68 5.44 5.06
107 INT165490 Regulation of Lpar1 8 0.45 15.31 5.05
108 INT351354 Localization of Lpar1 1 0.40 6.93 5.05
109 INT26042 Binding of Gria2 20 0.40 4.88 5.04
110 INT89114 Binding of Cftr 13 0.37 11.29 4.99
111 INT131176 Gene_expression of Srr 8 0.64 3.29 4.81
112 INT170757 Positive_regulation of Gene_expression of Cftr 3 0.51 11.41 4.75
113 INT114511 Positive_regulation of Gene_expression of Gria2 14 0.41 3.9 4.71
114 INT88790 Negative_regulation of Gene_expression of Dlg4 6 0.59 1.53 4.66
115 INT169756 Binding of CFTR 9 0.35 9.65 4.55
116 INT79682 Gene_expression of Grm7 6 0.75 4.74 4.5
117 INT115074 Positive_regulation of GRIA1 10 0.67 2.66 4.48
118 INT24930 Binding of Adrb2 6 0.26 4.18 4.44
119 INT119203 Gene_expression of CXADR 64 0.74 11.37 4.41
120 INT104299 Negative_regulation of Adam17 18 0.47 12.03 4.39
121 INT145532 Localization of Dlg4 25 0.79 1.97 4.36
122 INT100125 Negative_regulation of Accn3 11 0.59 5.85 4.32
123 INT74815 Binding of Grm5 11 0.36 3.62 4.25
124 INT87780 Gene_expression of Gja1 22 0.77 5.84 4.24
125 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
126 INT48993 Positive_regulation of Cftr 17 0.57 6.02 4.12
127 INT48784 Gene_expression of GRIA1 12 0.78 3.25 4.11
128 INT92902 Negative_regulation of Positive_regulation of Gria1 6 0.57 1.06 4.1
129 INT88787 Transcription of Dlg4 4 0.69 0.83 4.09
130 INT465 Binding of Adrb1 14 0.35 3.04 4.07
131 INT88156 Regulation of Gria1 12 0.54 2.5 4.06
132 INT120810 Binding of Dlg4 38 0.41 3.55 4.03
133 INT89113 Regulation of Cftr 11 0.62 6.83 4.01
134 INT140542 Gene_expression of SSTR2 18 0.65 13.58 3.94
135 INT48786 Phosphorylation of GRIA1 7 0.80 1.89 3.91
136 INT131178 Positive_regulation of Srr 4 0.56 4.78 3.91
137 INT276198 Positive_regulation of Pten 1 0.52 5.02 3.88
138 INT129990 Positive_regulation of Phosphorylation of Gria1 11 0.61 3.44 3.87
139 INT151099 Negative_regulation of CFTR 12 0.59 10.28 3.79
140 INT13425 Positive_regulation of Localization of Sstr2 4 0.67 0.19 3.65
141 INT16165 Regulation of DMD 114 0.60 35.13 3.64
142 INT79680 Binding of Grm7 6 0.47 2.83 3.58
143 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54
144 INT205196 Gene_expression of Lpar2 18 0.74 12.19 3.49
145 INT40653 Gene_expression of Sstr2 6 0.54 1.28 3.43
146 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36
147 INT171998 Binding of DMD 58 0.47 38.13 3.35
148 INT84564 Regulation of Positive_regulation of Gria1 2 0.33 1.86 3.3
149 INT51427 Positive_regulation of Positive_regulation of Gria1 11 0.45 1.33 3.28
150 INT170351 Positive_regulation of Gene_expression of Gria2 13 0.67 3.67 3.27
151 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
152 INT72256 Binding of Accn3 6 0.47 2.01 3.2
153 INT144068 Binding of Nsf 9 0.48 7.67 3.16
154 INT72618 Regulation of Tcf3 5 0.44 1.48 3.16
155 INT231377 Regulation of Gene_expression of Lpar1 7 0.53 5.55 3.12
156 INT13422 Regulation of Localization of Sstr2 4 0.44 0 3.1
157 INT170343 Positive_regulation of Gene_expression of Gria1 10 0.61 2.77 3.09
158 INT192676 Binding of PTEN 14 0.46 10.58 3.06
159 INT123802 Localization of Sstr2 8 0.80 3.54 3.01
160 INT165084 Transcription of Accn3 3 0.70 3.4 3.01
161 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
162 INT276842 Positive_regulation of Transcription of Accn3 2 0.49 3.32 2.93
163 INT351355 Positive_regulation of Localization of Lpar1 1 0.25 3.94 2.87
164 INT102157 Gene_expression of Adam17 3 0.58 4.17 2.86
165 INT159770 Positive_regulation of Gene_expression of Hcn2 2 0.67 2.65 2.82
166 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8
167 INT76715 Gene_expression of Gria3 16 0.75 1.89 2.77
168 INT169323 Positive_regulation of Gene_expression of Cxadr 4 0.67 4.09 2.77
169 INT33480 Gene_expression of Adrb2 4 0.66 1.96 2.77
170 INT100126 Localization of Accn3 7 0.77 2.73 2.76
171 INT119383 Gene_expression of Pten 11 0.59 10.33 2.73
172 INT115070 Binding of Accn3 4 0.47 3.8 2.7
173 INT211733 Phosphorylation of Gipc1 2 0.01 0 2.68
174 INT169088 Gene_expression of GRIA3 7 0.76 1.32 2.67
175 INT123978 Binding of GRIA1 3 0.41 3.5 2.62
176 INT131973 Positive_regulation of Transcription of Gria1 3 0.49 0.35 2.62
177 INT114513 Negative_regulation of Gene_expression of Gria2 8 0.48 0.89 2.61
178 INT139148 Negative_regulation of Gene_expression of Gria1 6 0.51 0.89 2.56
179 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54
180 INT69290 Localization of Cftr 11 0.75 3.69 2.52
181 INT170350 Localization of Gria1 7 0.65 2.36 2.51
182 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
183 INT34545 Positive_regulation of L1cam 12 0.60 1.18 2.5
184 INT132271 Positive_regulation of Gene_expression of Nsf 1 0.45 0.51 2.46
185 INT251126 Regulation of Dlg2 1 0.40 1.56 2.46
186 INT163544 Binding of Psen1 40 0.36 15.28 2.42
187 INT173236 Binding of Sstr2 8 0.25 1.64 2.41
188 INT153733 Negative_regulation of Transcription of Gria2 1 0.47 0 2.39
189 INT107656 Regulation of Gene_expression of Grm5 4 0.26 0.84 2.38
190 INT153108 Transcription of Srr 4 0.57 1.41 2.38
191 INT25666 Negative_regulation of ADRB1 11 0.44 3.12 2.33
192 INT13421 Positive_regulation of Sstr2 5 0.54 0.46 2.32
193 INT86315 Transcription of Cftr 7 0.53 4.24 2.3
194 INT132270 Regulation of Gene_expression of Nsf 1 0.44 0.46 2.3
195 INT4495 Gene_expression of Adrb1 7 0.66 2.43 2.29
196 INT177328 Positive_regulation of CXADR 9 0.48 4.29 2.27
197 INT202522 Negative_regulation of Gene_expression of Cftr 11 0.57 5.9 2.24
198 INT251127 Regulation of Gene_expression of Dlg2 1 0.35 1.49 2.23
199 INT131177 Regulation of Gene_expression of Srr 3 0.51 0.4 2.22
200 INT113608 Positive_regulation of Nsf 2 0.39 1.03 2.22
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