GO:0030182

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Name neuron differentiation
Categary Process
Go Slim No
Go Link GO:0030182
Unique Molecular Interactions 1218
Total Molecular Interactions 1648
Total Single Events 12609
Pain Genes Associated 99

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neuron differentiation. They are ordered first by their pain relevance and then by number of times they were reported for neuron differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
2 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
3 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
4 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
5 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
6 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
7 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
8 INT289979 Binding of Helt and Negative_regulation of Maoa 1 0.00 0.17 3.14
9 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
10 INT152699 Bdnf Positive_regulation of Ltp 5 0.05 1.22 2.95
11 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
12 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
13 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
14 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
15 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
16 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
17 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37
18 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
19 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
20 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
21 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
22 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
23 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
24 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
25 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
26 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
27 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
28 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
29 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
30 INT334345 Binding of GRP and Helt 1 0.02 0 1.79
31 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79
32 INT142073 Binding of Helt and Nrm 1 0.00 0 1.74
33 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
34 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
35 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
36 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
37 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
38 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
39 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
40 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
41 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
42 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
43 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
44 INT6976 Helt Regulation of Gene_expression of St8sia1 1 0.00 0.07 1.45
45 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
46 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
47 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
48 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
49 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
50 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
51 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
52 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
53 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
54 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
55 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
56 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
57 INT96708 Bdnf Positive_regulation of Localization of SST 1 0.01 0 1.3
58 INT148778 Binding of Usf1 and Rtn1 1 0.40 0.85 1.3
59 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
60 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
61 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
62 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
63 INT50386 Bdnf Regulation of Npy 1 0.21 0.47 1.24
64 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
65 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23
66 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
67 INT298260 Binding of Runx3 and Pou4f1 1 0.52 2.08 1.22
68 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2
69 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
70 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17
71 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
72 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
73 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
74 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
75 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
76 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11
77 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
78 INT298272 Runx1 Positive_regulation of Gene_expression of Ntrk3 1 0.52 0.88 1.09
79 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09
80 INT87320 Ngf Regulation of Gene_expression of Bdnf 2 0.38 0.97 1.06
81 INT134534 Binding of Bdnf and Psds1 1 0.01 0 1.05
82 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04
83 INT224856 Binding of Bdnf and Eef2 1 0.14 0 1.02
84 INT12138 Ins1 Negative_regulation of Chat 1 0.27 0.71 1.01
85 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
86 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
87 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
88 INT180770 Gdnf Positive_regulation of Zbtb38 1 0.00 0.27 0.99
89 INT69307 Prkcq Negative_regulation of TH1L 1 0.00 0.98 0.98
90 INT56742 LIF Positive_regulation of Chat 1 0.02 0.2 0.98
91 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98
92 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
93 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
94 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
95 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
96 INT180780 Ngf Regulation of Gdnf 1 0.22 0.28 0.96
97 INT180803 Sorbs1 Regulation of Gdnf 1 0.01 0.28 0.95
98 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
99 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93
100 INT82126 CEBPB Regulation of Gene_expression of Oprd1 1 0.00 0 0.93
101 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 0.09 0.18 0.93
102 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
103 INT318461 Nnat Positive_regulation of Mapk14 1 0.05 0.97 0.92
104 INT147505 Binding of Ret and Gdnf 1 0.27 0.81 0.92
105 INT82120 IK Positive_regulation of CEBPB 1 0.00 0 0.92
106 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
107 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
108 INT180772 Bdnf Regulation of Trpv1 1 0.11 0.29 0.9
109 INT180777 Bdnf Regulation of Gene_expression of Trpv1 1 0.18 0.29 0.9
110 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89
111 INT152700 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
112 INT152701 Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
113 INT242621 Gdnf Positive_regulation of Gene_expression of Scn11a 1 0.05 0.12 0.88
114 INT318462 Nnat Positive_regulation of Nfkb1 1 0.46 0.9 0.88
115 INT152694 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
116 INT48463 Bdnf Positive_regulation of Gene_expression of Sst 1 0.25 0 0.88
117 INT326455 Runx1 Positive_regulation of Gene_expression of Trpv1 1 0.45 0 0.88
118 INT152695 Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
119 INT261783 Bdnf Regulation of Gene_expression of Slc12a5 1 0.09 0 0.87
120 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87
121 INT298295 Runx1 Negative_regulation of Gene_expression of Ntrk1 2 0.38 0.45 0.86
122 INT215596 Bdnf Positive_regulation of Negative_regulation of Slc12a5 1 0.14 0.76 0.86
123 INT251706 Chat Regulation of Gene_expression of Acot1 1 0.06 1.64 0.85
124 INT261786 Bdnf Negative_regulation of Slc12a5 1 0.14 0.05 0.85
125 INT251708 Chat Regulation of Acot1 1 0.03 1.64 0.84
126 INT12142 Ins1 Regulation of Chat 1 0.24 0.69 0.84
127 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
128 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
129 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
130 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
131 INT298279 Pou4f1 Positive_regulation of Gene_expression of Runx3 1 0.50 1.31 0.81
132 INT103331 Ngf Positive_regulation of Gdnf 1 0.01 0.57 0.8
133 INT128042 Bdnf Positive_regulation of Phosphorylation of Ephb1 1 0.22 0.2 0.8
134 INT144451 Napa Positive_regulation of Gene_expression of Nqo1 1 0.07 0.18 0.8
135 INT180782 Bdnf Positive_regulation of Calca 1 0.16 0.77 0.8
136 INT245564 Runx3 Negative_regulation of Ntrk2 3 0.61 1.61 0.79
137 INT128041 Bdnf Positive_regulation of Trib3 1 0.10 0.29 0.79
138 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78
139 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
140 INT103334 Gdnf Regulation of Gene_expression of TRPV1 1 0.02 0.53 0.77
141 INT351322 Nts Regulation of Localization of Napa 1 0.01 0.56 0.77
142 INT224281 Bdnf Regulation of Gene_expression of Gap43 1 0.36 0.4 0.77
143 INT103333 Gdnf Regulation of TRPV1 1 0.02 0.53 0.77
144 INT224283 Bdnf Regulation of Gene_expression of Calca 1 0.19 0.35 0.76
145 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
146 INT69692 Helt Regulation of Prkaca 1 0.00 0.33 0.76
147 INT18447 Binding of Ache and Chat 2 0.33 0.33 0.73
148 INT180773 Calca Regulation of Binding of Gdnf 1 0.18 0.15 0.72
149 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
150 INT334348 GRP Regulation of Helt 1 0.01 0 0.72
151 INT180765 Calca Regulation of Binding of Bdnf 1 0.15 0.15 0.72
152 INT326457 Runx1 Regulation of Mrgpra3 1 0.37 0.1 0.71
153 INT180783 Binding of Gdnf and Man2a2 1 0.00 0.52 0.71
154 INT326456 Runx1 Regulation of Pip4k2b 1 0.09 0.11 0.71
155 INT68211 Binding of Calca and Chat 1 0.37 0 0.71
156 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
157 INT180775 Binding of Gdnf and Gfra1 1 0.06 0.52 0.71
158 INT102121 Gdnf Regulation of Gene_expression of Cnr1 1 0.45 0.42 0.71
159 INT144367 Gdnf Negative_regulation of Positive_regulation of Th 1 0.11 0.77 0.7
160 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
161 INT351375 Mir470 Negative_regulation of Ntrk2 1 0.01 1.54 0.7
162 INT219035 Nkx1-1 Regulation of Gene_expression of Bdnf 1 0.13 0.88 0.7
163 INT224892 Bdnf Regulation of Localization of Ltp 1 0.03 0.17 0.69
164 INT224893 Bdnf Regulation of Ltp 1 0.03 0.17 0.69
165 INT197233 Positive_regulation of Rora Positive_regulation of Localization of Helt 1 0.00 0 0.68
166 INT161186 Bdnf Regulation of Gene_expression of Ntrk2 1 0.44 1.05 0.68
167 INT114036 Binding of Grin1 and Psd 1 0.24 0.45 0.68
168 INT152923 Aanat Positive_regulation of Helt 1 0.00 0.42 0.67
169 INT142244 Positive_regulation of Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67
170 INT180805 Bdnf Regulation of Sorbs1 1 0.01 0.14 0.67
171 INT161183 NMS Positive_regulation of Gene_expression of Bdnf 1 0.40 1.3 0.67
172 INT142243 Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67
173 INT161184 NMS Positive_regulation of Gene_expression of Ntrk2 1 0.55 1.3 0.67
174 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
175 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
176 INT82306 Bdnf Positive_regulation of Gene_expression of Fos 1 0.68 0.64 0.65
177 INT135361 Prr14 Positive_regulation of Mecp2 1 0.24 0.15 0.64
178 INT135363 Mecp2 Positive_regulation of Mbd1 1 0.50 0.15 0.64
179 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
180 INT148776 Binding of Usf2 and Rtn1 1 0.38 0.42 0.64
181 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
182 INT298262 Pou4f1 Positive_regulation of Positive_regulation of Ntrk3 1 0.36 0.79 0.63
183 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
184 INT122777 Gdnf Negative_regulation of Gene_expression of Trpv1 1 0.36 0.8 0.62
185 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
186 INT93690 Bdnf Regulation of Localization of Tacr1 1 0.10 0.28 0.61
187 INT257717 Binding of Bdnf and Vgf 1 0.25 0.86 0.61
188 INT284089 Binding of NTRK2 and SERPINE1 1 0.27 0.73 0.61
189 INT122774 Gdnf Negative_regulation of Positive_regulation of Trpv1 1 0.32 0.78 0.61
190 INT96228 COX5A Regulation of Ak1 1 0.01 0.6 0.6
191 INT271194 Binding of Bdnf and Gopc 1 0.03 0.49 0.6
192 INT90119 Ntrk2 Regulation of Gene_expression of Nfkb1 1 0.01 0.27 0.6
193 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
194 INT79740 Ntf3 Regulation of Positive_regulation of Ntrk2 1 0.28 0 0.6
195 INT54942 Rb1 Regulation of Gab1 1 0.02 0.39 0.59
196 INT164455 Ngf Negative_regulation of Bdnf 1 0.05 0.59 0.59
197 INT284790 Trpa1 Positive_regulation of Regulation of Napa 1 0.19 0 0.59
198 INT284784 Trpv1 Positive_regulation of Regulation of Napa 1 0.20 0 0.59
199 INT280895 Runx1 Positive_regulation of Gene_expression of Ret 2 0.33 0.2 0.58
200 INT242584 Gdnf Regulation of Gene_expression of Qrfp 1 0.00 0.09 0.58

Single Events

The table below shows the top 100 pain related interactions that have been reported for neuron differentiation. They are ordered first by their pain relevance and then by number of times they were reported in neuron differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1
2 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
3 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82
4 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
5 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01
6 INT67682 Localization of Bdnf 204 0.81 72.36 88.92
7 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16
8 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5
9 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06
10 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24
11 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
12 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
13 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
14 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55
15 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
16 INT60388 Gene_expression of Helt 90 0.07 19.18 41.72
17 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64
18 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
19 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49
20 INT11796 Positive_regulation of Helt 52 0.31 11.7 29.22
21 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5
22 INT47685 Positive_regulation of Positive_regulation of Bdnf 32 0.70 20.05 27.03
23 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
24 INT77793 Positive_regulation of Gdnf 54 0.70 23.76 25.08
25 INT96557 Binding of Bdnf 46 0.47 21.74 24.26
26 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
27 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
28 INT168482 Gene_expression of Nnat 45 0.77 24.01 21.53
29 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59
30 INT13244 Binding of Helt 30 0.31 4.56 18.01
31 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23
32 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
33 INT96299 Positive_regulation of Localization of Bdnf 35 0.70 15.67 16.09
34 INT6381 Negative_regulation of Chat 51 0.59 19.68 15.86
35 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
36 INT4851 Positive_regulation of Chat 53 0.70 9.21 15.11
37 INT16266 Gene_expression of Chat 80 0.67 16.14 15.01
38 INT11945 Regulation of Chat 38 0.62 7.75 14.97
39 INT11795 Negative_regulation of Helt 33 0.28 6.51 14.76
40 INT4736 Gene_expression of Chat 67 0.77 17.15 14.24
41 INT13572 Localization of Helt 31 0.36 5.85 13.41
42 INT102897 Positive_regulation of Gene_expression of Gdnf 34 0.69 11.13 13.28
43 INT47692 Negative_regulation of Positive_regulation of Bdnf 18 0.59 9.64 13.14
44 INT65172 Negative_regulation of Ntrk2 35 0.59 9.89 13.08
45 INT41728 Gene_expression of CHAT 65 0.75 42.19 12.73
46 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
47 INT245517 Positive_regulation of Gene_expression of Runx1 49 0.69 17.7 12.38
48 INT133212 Negative_regulation of Runx1 21 0.58 11.16 11.89
49 INT56048 Positive_regulation of Transcription of Bdnf 24 0.70 8.33 11.83
50 INT203473 Gene_expression of Pou4f1 69 0.76 25.94 11.36
51 INT79981 Positive_regulation of Gene_expression of Gdnf 27 0.70 12.49 10.77
52 INT82950 Positive_regulation of Gdnf 36 0.51 11.72 10.5
53 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
54 INT85844 Regulation of Gdnf 18 0.50 11.08 10.43
55 INT133210 Positive_regulation of Runx1 33 0.69 18.25 10.12
56 INT245538 Negative_regulation of Gene_expression of Runx1 20 0.58 11.68 9.97
57 INT29988 Gene_expression of Mecp2 27 0.78 5.45 9.47
58 INT98111 Negative_regulation of Gdnf 12 0.59 10.85 9.29
59 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
60 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75
61 INT26795 Gene_expression of Mtpn 44 0.62 27.66 8.62
62 INT47682 Transcription of Ntrk2 19 0.69 6.32 8.6
63 INT77795 Localization of Gdnf 26 0.81 6.29 8.55
64 INT33944 Regulation of Helt 13 0.24 2.86 8.49
65 INT318459 Positive_regulation of Gene_expression of Nnat 1 0.60 9.92 8.49
66 INT15308 Localization of Chat 29 0.81 2.35 8.47
67 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
68 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
69 INT77794 Binding of Gdnf 15 0.48 8.38 8.22
70 INT135443 Phosphorylation of Map2k1 11 0.80 2.44 8.01
71 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
72 INT135441 Positive_regulation of Map2k1 15 0.67 6.6 7.87
73 INT92003 Positive_regulation of Transcription of Gdnf 10 0.66 5.54 7.84
74 INT48314 Gene_expression of NTRK2 17 0.75 7.84 7.83
75 INT98178 Localization of Casp3 32 0.65 21.01 7.77
76 INT87546 Transcription of Gdnf 15 0.71 7.49 7.76
77 INT29583 Positive_regulation of Agtr2 30 0.45 21.47 7.04
78 INT47691 Positive_regulation of Gene_expression of Ntrk2 17 0.62 13.64 6.96
79 INT92001 Regulation of Gene_expression of Gdnf 12 0.62 6.62 6.65
80 INT2513 Binding of Napa 80 0.42 4.29 6.51
81 INT93137 Negative_regulation of Map2k1 17 0.42 4.51 6.49
82 INT50328 Positive_regulation of Vgf 8 0.70 13.98 6.37
83 INT47681 Regulation of Ntrk2 17 0.62 3.61 6.31
84 INT169596 Transcription of Runx1 12 0.71 5.55 6.27
85 INT245515 Regulation of Runx1 14 0.61 5.07 6.22
86 INT57232 Binding of Casp3 22 0.36 9.42 6.2
87 INT144539 Phosphorylation of Mecp2 3 0.82 6.18 6.2
88 INT91065 Regulation of Transcription of Bdnf 13 0.62 12.48 6.13
89 INT135359 Positive_regulation of Mecp2 4 0.70 4.35 6.05
90 INT105215 Negative_regulation of Pou4f1 16 0.53 9.42 5.97
91 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
92 INT87548 Negative_regulation of Gene_expression of Gdnf 9 0.54 5.67 5.94
93 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
94 INT115087 Negative_regulation of Gdnf 10 0.51 5.78 5.73
95 INT56047 Negative_regulation of Transcription of Bdnf 16 0.59 8.02 5.67
96 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
97 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
98 INT106552 Positive_regulation of Gene_expression of Ntrk2 19 0.68 9.72 5.51
99 INT168483 Regulation of Gene_expression of Nnat 3 0.61 5.93 5.5
100 INT42312 Negative_regulation of Chat 14 0.54 6.13 5.44
101 INT107103 Negative_regulation of Ntrk2 21 0.59 10.38 5.28
102 INT135440 Positive_regulation of Phosphorylation of Map2k1 5 0.49 1.32 5.22
103 INT110666 Phosphorylation of Bdnf 12 0.69 5.67 5.21
104 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2
105 INT123422 Gene_expression of Lmx1b 18 0.78 6.93 5.17
106 INT67681 Negative_regulation of Localization of Bdnf 12 0.50 4.37 5.07
107 INT106555 Binding of Ntrk2 15 0.48 6.31 5.05
108 INT245536 Regulation of Gene_expression of Runx1 11 0.58 6.22 4.88
109 INT203506 Positive_regulation of Pou4f1 3 0.49 6.17 4.85
110 INT203443 Gene_expression of Isl1 27 0.67 11.12 4.65
111 INT78626 Regulation of Gdnf 7 0.45 3.3 4.64
112 INT78995 Negative_regulation of Agtr2 26 0.42 13.05 4.56
113 INT65056 Binding of Ntrk2 20 0.36 3.72 4.42
114 INT17818 Gene_expression of Agtr2 24 0.56 12.96 4.41
115 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
116 INT122882 Regulation of Ntrk2 13 0.62 9.7 4.3
117 INT109219 Negative_regulation of Cdk5r1 5 0.43 1.22 4.25
118 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
119 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
120 INT47686 Regulation of Gene_expression of Ntrk2 5 0.44 5.24 4.14
121 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
122 INT72385 Phosphorylation of Shc1 11 0.52 1.62 4.1
123 INT106065 Negative_regulation of MAP2K1 27 0.57 12.69 3.97
124 INT200047 Negative_regulation of Gene_expression of Ntrk2 8 0.56 10.78 3.95
125 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
126 INT17819 Regulation of Agtr2 10 0.51 9.33 3.9
127 INT105217 Regulation of Pou4f1 8 0.60 6.15 3.88
128 INT4012 Negative_regulation of Psd 23 0.52 14.12 3.81
129 INT50295 Regulation of Mtpn 13 0.26 7.54 3.77
130 INT5782 Gene_expression of Edn3 17 0.67 3.38 3.65
131 INT134527 Phosphorylation of Ntrk2 7 0.69 3.72 3.65
132 INT48449 Regulation of Chat 11 0.61 4.24 3.64
133 INT82305 Regulation of Localization of Bdnf 10 0.40 3 3.62
134 INT318967 Gene_expression of Mecp2 9 0.77 11.52 3.55
135 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
136 INT257727 Transcription of Vgf 1 0.72 7.38 3.52
137 INT78625 Regulation of Gene_expression of Gdnf 7 0.37 2.5 3.47
138 INT132385 Gene_expression of Neurog2 12 0.73 7.03 3.44
139 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
140 INT349080 Binding of Rtn1 1 0.32 5.68 3.21
141 INT50326 Gene_expression of Vgf 11 0.78 4.41 3.2
142 INT48462 Positive_regulation of Negative_regulation of Bdnf 8 0.70 1 3.2
143 INT183212 Positive_regulation of Regulation of Bdnf 4 0.45 1.57 3.14
144 INT115301 Negative_regulation of Binding of Napa 16 0.33 0.6 3.11
145 INT29929 Gene_expression of Rb1 20 0.69 5.81 3.1
146 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
147 INT55033 Localization of Edn3 7 0.80 1.4 3.05
148 INT134470 Positive_regulation of Map2k1 74 0.49 46.07 3.02
149 INT72384 Positive_regulation of Phosphorylation of Shc1 1 0.32 0.48 2.9
150 INT209744 Transcription of Gdnf 5 0.67 1.36 2.84
151 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
152 INT142237 Phosphorylation of Ntrk2 8 0.82 2.24 2.82
153 INT133144 Localization of Mtpn 18 0.24 7.88 2.77
154 INT27207 Gene_expression of Psd 31 0.73 15.44 2.75
155 INT201632 Positive_regulation of Cdk5r1 20 0.40 21.6 2.75
156 INT215185 Localization of Nnat 7 0.69 3.62 2.75
157 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74
158 INT280459 Regulation of Gene_expression of Ntrk2 13 0.62 8.48 2.71
159 INT54938 Regulation of Rb1 6 0.44 4.41 2.69
160 INT143841 Positive_regulation of Mtpn 17 0.17 5.46 2.68
161 INT115300 Negative_regulation of Napa 7 0.23 1 2.68
162 INT119516 Positive_regulation of Phosphorylation of Bdnf 3 0.21 2.81 2.68
163 INT105598 Negative_regulation of Mtpn 15 0.16 11.83 2.65
164 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
165 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
166 INT176531 Gene_expression of SHC1 3 0.67 9.5 2.62
167 INT47386 Negative_regulation of CHAT 5 0.29 1.63 2.61
168 INT69007 Binding of Cebpb 10 0.48 2.21 2.6
169 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
170 INT132685 Negative_regulation of NTRK2 4 0.42 2.89 2.58
171 INT50325 Regulation of Vgf 2 0.62 4.4 2.58
172 INT63846 Gene_expression of Prkcq 1 0.73 1.11 2.58
173 INT98871 Regulation of Psd 8 0.42 4.55 2.57
174 INT136681 Gene_expression of Shc1 13 0.77 9.67 2.52
175 INT67621 Negative_regulation of Gene_expression of Ntrk2 7 0.41 2.71 2.52
176 INT167096 Positive_regulation of Gene_expression of Helt 10 0.05 0.89 2.49
177 INT95799 Binding of NTRK2 8 0.35 2.95 2.47
178 INT50723 Positive_regulation of Nr4a2 7 0.53 0.47 2.46
179 INT131112 Phosphorylation of Casp3 7 0.63 4.1 2.46
180 INT163544 Binding of Psen1 40 0.36 15.28 2.42
181 INT109559 Localization of Napa 16 0.61 1.3 2.42
182 INT144366 Negative_regulation of Positive_regulation of Gdnf 4 0.41 1.43 2.41
183 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36
184 INT11943 Transcription of Chat 10 0.70 1.55 2.36
185 INT101603 Positive_regulation of Cdk5r1 4 0.56 1.12 2.35
186 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31
187 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
188 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
189 INT98650 Positive_regulation of Localization of Gdnf 4 0.68 0.94 2.27
190 INT47687 Positive_regulation of Transcription of Ntrk2 5 0.45 2.42 2.24
191 INT60279 Gene_expression of VHL 70 0.78 75.21 2.21
192 INT107102 Negative_regulation of Positive_regulation of Ntrk2 6 0.54 1.61 2.21
193 INT96575 Gene_expression of Bhlhe22 5 0.65 1.97 2.21
194 INT168945 Positive_regulation of Binding of Bdnf 4 0.50 1.7 2.14
195 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
196 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
197 INT22282 Positive_regulation of Chat 8 0.67 2.82 2.12
198 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12
199 INT144364 Negative_regulation of Lmx1b 5 0.45 3.35 2.12
200 INT144580 Regulation of S1pr1 1 0.44 0.32 2.1
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